azathioprine has been researched along with Tuberculosis, Multidrug-Resistant in 2 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Tuberculosis, Multidrug-Resistant: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Asymptomatic man receiving maintenance azathioprine therapy for Crohn disease whose wife had multidrug-resistant pulmonary tuberculosis." | 3.72 | Early diagnosis of subclinical multidrug-resistant tuberculosis. ( Ewer, K; Fabbri, LM; Hansell, DM; Lalvani, A; Losi, M; Richeldi, L; Roversi, P, 2004) |
| "Azathioprine was discontinued due to hematological toxicity and failure to control SLE." | 1.42 | First report of multi-drug resistant tuberculosis in a systemic lupus erythematosus patient. ( Dierberg, KL; Dorjee, K; Reingold, AL; Sadutshang, TD, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dorjee, K | 1 |
| Dierberg, KL | 1 |
| Sadutshang, TD | 1 |
| Reingold, AL | 1 |
| Richeldi, L | 1 |
| Ewer, K | 1 |
| Losi, M | 1 |
| Hansell, DM | 1 |
| Roversi, P | 1 |
| Fabbri, LM | 1 |
| Lalvani, A | 1 |
2 other studies available for azathioprine and Tuberculosis, Multidrug-Resistant
| Article | Year |
|---|---|
First report of multi-drug resistant tuberculosis in a systemic lupus erythematosus patient.
Topics: Adrenal Cortex Hormones; Antitubercular Agents; Azathioprine; Female; Femur Head Necrosis; Humans; I | 2015 |
Early diagnosis of subclinical multidrug-resistant tuberculosis.
Topics: Adult; Antigens, Bacterial; Azathioprine; Bronchoalveolar Lavage; Crohn Disease; Early Diagnosis; Fe | 2004 |