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azathioprine and Thymus Neoplasms

azathioprine has been researched along with Thymus Neoplasms in 29 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Thymus Neoplasms: Tumors or cancer of the THYMUS GLAND.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting."7.79Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013)
"To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting."3.79Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013)
" Under immunosuppressive treatment with azathioprine and steroids, the patient developed cytomegalovirus (CMV) enteritis which was triggered by therapy-induced leukopenia."3.75[A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection]. ( Baba, HA; Gerken, G; Kahraman, A; Maldonado-Lopez, E; Miller, M; Treichel, U, 2009)
" Here we report the case of a patient with myasthenia gravis receiving long-term immunosuppression with azathioprine and recurrent well-differentiated thymic carcinoma who developed CD4+ T-cell depletion and CNS cryptococcosis after multiple courses of chemotherapy and mediastinal irradiation."3.70Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis. ( Padberg, F; Schmidt, S, 1998)
"6 years after resection and postirradiation of an "asymptomatic" thymoma, myasthenia gravis developed in a 46 year old man which improved within 6 months following initiation of immunosuppressive therapy with azathioprine."3.65[Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)]. ( Fischer, K; Janzen, RW; Lachenmayer, L, 1977)
"Myasthenia gravis is caused by antibodies against acetylcholine receptors and is treated with inhibition or elimination of antibody production."2.41[A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy]. ( Inoue, Y; Matsuda, O; Takahashi, K; Takemura, T; Yoshimura, A, 2000)
"Limbic encephalitis is typically characterised by a sub-acute onset of disorientation, amnesia and seizures, but the clinical spectrum is not yet fully defined and the syndrome could be under-diagnosed."1.35Hypothermia in VGKC antibody-associated limbic encephalitis. ( Clover, L; Grubneac, A; Irani, SR; Jacob, S; Rajabally, YA; Vincent, A; Walters, RJ; Yazaki, M, 2008)
"A group of 16 patients with severe generalized myasthenia gravis (MG) (five with thymoma) that was resistant to anticholinesterases, thymectomy, and corticosteroids were treated by plasmapheresis."1.26Plasmapheresis in refractory generalized myasthenia gravis. ( Ambinder, EP; Bender, AN; Genkins, G; Goldberg, J; Kornfeld, P; Mittag, T; Papatestas, AE, 1981)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199015 (51.72)18.7374
1990's7 (24.14)18.2507
2000's4 (13.79)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pedersen, EG1
Pottegård, A1
Hallas, J1
Friis, S1
Hansen, K1
Jensen, PE1
Gaist, D1
Benjamin, B1
Zaltzman, R1
Shpitz, B1
Gordon, CR1
Avital, S1
Kahraman, A1
Miller, M1
Maldonado-Lopez, E1
Baba, HA1
Treichel, U1
Gerken, G1
Rigamonti, A1
Lauria, G1
Piamarta, F1
Fiumani, A1
Agostoni, E1
Romi, F1
Gilhus, NE1
Varhaug, JE1
Myking, A1
Aarli, JA1
Jacob, S1
Irani, SR1
Rajabally, YA1
Grubneac, A1
Walters, RJ1
Yazaki, M1
Clover, L1
Vincent, A1
Schumm, F1
Brinkmann, A1
Fateh-Moghadam, A1
Cohen, SM1
Erturk, E1
Skibba, JL1
Bryan, GT1
Kornfeld, P1
Ambinder, EP1
Mittag, T1
Bender, AN1
Papatestas, AE1
Goldberg, J1
Genkins, G1
Ito, N1
Mukaida, T1
Aoe, M1
Yamashita, M1
Date, H1
Ando, A1
Shimizu, N1
Beekman, R1
Kuks, JB1
Oosterhuis, HJ1
Schmidt, S1
Padberg, F1
Crawford, WW1
Yusin, JS1
Klaustermeyer, WB1
Takahashi, K1
Inoue, Y1
Matsuda, O1
Takemura, T1
Yoshimura, A1
Janzen, RW1
Lachenmayer, L1
Fischer, K1
Arimori, S1
Nakata, Y1
Tada, S1
Kobashi, H1
Koriyama, K1
Ichikawa, Y1
Mitsuhashi, A1
Iwasaki, I1
Hiraki, K1
Zimmermann, CW1
Lingenfelser, T1
Melms, A1
Jakober, B1
Kumagai, M1
Kondou, T1
Handa, M1
Shiraishi, Y1
Fujimura, S1
Nakata, T1
Mathieson, PW1
O'Neill, JH1
Durrant, ST1
Henderson, SJ1
Green, PJ1
Newsom-Davis, J1
Pan, CH1
Chiang, CY1
Chen, SS1
Herrmann, C1
Lindstrom, JM1
Keesey, JC1
Mulder, DG1
Krueger, GR2
O'Conor, GT1
Sussman, E1
Tralka, TS1
Casey, TP1
Ricken, D1
Heine, UI1
Marmont, A1
Gori, E1
Krüger, GR1
Böttcher, D1
Maas, D1
Wendt, F1
Schubothe, H1

Reviews

3 reviews available for azathioprine and Thymus Neoplasms

ArticleYear
[A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy].
    Nihon Jinzo Gakkai shi, 2000, Volume: 42, Issue:5

    Topics: Azathioprine; Female; Humans; Immunosuppressive Agents; Middle Aged; Myasthenia Gravis; Nephrosis, L

2000
Thymolipoma in patients with myasthenia gravis: report of two cases and review.
    Acta neurologica Scandinavica, 1988, Volume: 78, Issue:1

    Topics: Azathioprine; Female; Humans; Lipoma; Middle Aged; Myasthenia Gravis; Prednisolone; Thymus Neoplasms

1988
Myasthenia gravis--current concepts.
    The Western journal of medicine, 1985, Volume: 142, Issue:6

    Topics: Acetylcholine; Adrenal Cortex Hormones; Adult; Animals; Autoantibodies; Autoimmune Diseases; Azathio

1985

Other Studies

26 other studies available for azathioprine and Thymus Neoplasms

ArticleYear
Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark.
    European journal of neurology, 2013, Volume: 20, Issue:6

    Topics: Aged; Aged, 80 and over; Azathioprine; Case-Control Studies; Denmark; Female; Humans; Male; Middle A

2013
Presacral Mass Discovered during Pregnancy followed by Myasthenia Gravis.
    The Israel Medical Association journal : IMAJ, 2015, Volume: 17, Issue:5

    Topics: Adult; Azathioprine; Castleman Disease; Cholinesterase Inhibitors; Female; Humans; Immunosuppressive

2015
[A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection].
    Medizinische Klinik (Munich, Germany : 1983), 2009, Feb-15, Volume: 104, Issue:2

    Topics: Agammaglobulinemia; Antiviral Agents; Azathioprine; Cidofovir; Colitis, Ulcerative; Cytomegalovirus

2009
Thymoma-associated myasthenia gravis without acetylcholine receptor antibodies.
    Journal of the neurological sciences, 2011, Mar-15, Volume: 302, Issue:1-2

    Topics: Action Potentials; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Electric Stimulation; Evo

2011
Disease severity and outcome in thymoma myasthenia gravis: a long-term observation study.
    European journal of neurology, 2003, Volume: 10, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Age of Onset; Autoantibodies; Azathioprine; Combined Modality Therap

2003
Hypothermia in VGKC antibody-associated limbic encephalitis.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:2

    Topics: Aged; Atrophy; Autoantibodies; Azathioprine; Cyclosporine; Dominance, Cerebral; Epilepsy, Temporal L

2008
[Antibody-controlled cytostatic therapy of malignant thymoma with concomitant myasthenia gravis].
    Deutsche medizinische Wochenschrift (1946), 1984, Aug-17, Volume: 109, Issue:33

    Topics: Acetylcholine; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Cyclophosph

1984
Azathioprine induction of lymphomas and squamous cell carcinomas in rats.
    Cancer research, 1983, Volume: 43, Issue:6

    Topics: Animals; Azathioprine; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Lymphoma; Rats; Rats, Inbred

1983
Plasmapheresis in refractory generalized myasthenia gravis.
    Archives of neurology, 1981, Volume: 38, Issue:8

    Topics: Adult; Aged; Antibodies; Azathioprine; Cholinesterases; Female; Humans; Male; Middle Aged; Myastheni

1981
[Treatment of myasthenia gravis--pathophysiological evaluation of various forms of treatment and practical aspects of therapy (author's transl)].
    No to shinkei = Brain and nerve, 1980, Volume: 32, Issue:9

    Topics: Azathioprine; Cholinesterase Inhibitors; Evaluation Studies as Topic; Humans; Myasthenia Gravis; Pla

1980
[Four cases of thymoma associated with pure red cell aplasia].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1997, Volume: 45, Issue:1

    Topics: Adult; Aged; Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged

1997
Myasthenia gravis: diagnosis and follow-up of 100 consecutive patients.
    Journal of neurology, 1997, Volume: 244, Issue:2

    Topics: Age of Onset; Aged; Autoimmune Diseases; Azathioprine; Cholinesterase Inhibitors; Cohort Studies; Di

1997
Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis.
    Journal of the neurological sciences, 1998, May-07, Volume: 157, Issue:2

    Topics: Adult; Age Factors; Azathioprine; Carcinoma; CD4-Positive T-Lymphocytes; Female; Humans; Immunologic

1998
Nonsurgical regression of thymoma following corticosteroid/azathioprine therapy.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 83, Issue:1

    Topics: Adrenal Cortex Hormones; Agammaglobulinemia; Azathioprine; Common Variable Immunodeficiency; Humans;

1999
[Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)].
    Medizinische Klinik, 1977, Nov-11, Volume: 72, Issue:45

    Topics: Adult; Antibodies, Antinuclear; Azathioprine; Humans; Male; Middle Aged; Myasthenia Gravis; Pyridost

1977
[A case of thymoma with myasthenia gravis and pure red cell aplasia treated with thymectomy and azathioprine (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, Apr-10, Volume: 67, Issue:4

    Topics: Aged; Anemia, Aplastic; Azathioprine; Humans; Male; Myasthenia Gravis; Thymectomy; Thymoma; Thymus N

1978
[Abscess of the thyroid gland caused by Salmonella enteritidis in immunosuppressive treatment of generalized myasthenia gravis with thymoma].
    Der Nervenarzt, 1990, Volume: 61, Issue:10

    Topics: Abscess; Aged; Azathioprine; Humans; Middle Aged; Myasthenia Gravis; Opportunistic Infections; Risk

1990
[Treatment of invasive thymoma with myasthenia gravis: a case report responsive to azathioprine and methylprednisolone].
    Kyobu geka. The Japanese journal of thoracic surgery, 1990, Volume: 43, Issue:3

    Topics: Adult; Azathioprine; Drug Therapy, Combination; Humans; Male; Methylprednisolone; Myasthenia Gravis;

1990
Antibody-mediated pure neutrophil aplasia, recurrent myasthenia gravis and previous thymoma: case report and literature review.
    The Quarterly journal of medicine, 1990, Volume: 74, Issue:273

    Topics: Adult; Agranulocytosis; Antibodies; Azathioprine; Bone Marrow; Female; Humans; Immunosuppression The

1990
Ultrastructural and tissue culture studies of a thymic lymphoma induced by persistent antigenic stimulation and immunosuppression.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1973, Jun-19, Volume: 79, Issue:4

    Topics: Animals; Antigens, Neoplasm; Azathioprine; Cells, Cultured; Cross Reactions; Immunosuppression Thera

1973
Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.
    Clinical and experimental immunology, 1968, Volume: 3, Issue:4

    Topics: Albuminuria; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Coombs Test; Glomerulonephritis;

1968
[Current results of the treatment of pseudoparalytic myasthenia gravis with immunosuppressive agents].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Antibodies; Antilymphocyte Serum; Azathioprine; Cholinesterase I

1972
Morphogenesis of two immunologically induced mouse lymphomas.
    Cancer research, 1972, Volume: 32, Issue:3

    Topics: Animals; Azathioprine; Cells, Cultured; Female; Hodgkin Disease; Liver; Lung; Lymph Nodes; Mice; Mic

1972
[Pure erythroblastic aplasia associated with thymoma in an adult. Complete remission after immunodepressive therapy].
    Minerva medica, 1973, Sep-05, Volume: 64, Issue:61

    Topics: Anemia, Aplastic; Azathioprine; Cyclophosphamide; Hemangiosarcoma; Humans; Immunosuppressive Agents;

1973
Host response during the latent period and the growth of an immunologically induced mouse lymphoma.
    Beitrage zur Pathologie, 1972, Volume: 146, Issue:2

    Topics: Animals; Antibody Formation; Antigens, Neoplasm; Azathioprine; Cross Reactions; Female; Freund's Adj

1972
[Anemia caused by erythroblastopenia in adult age].
    Klinische Wochenschrift, 1970, Jan-15, Volume: 48, Issue:2

    Topics: Aged; Analgesics; Anemia, Aplastic; Azathioprine; Blood Transfusion; Female; Heart Failure; Hepatiti

1970