azathioprine has been researched along with Thymoma in 36 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Thymoma: A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting." | 7.79 | Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013) |
| "To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting." | 3.79 | Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013) |
| " Under immunosuppressive treatment with azathioprine and steroids, the patient developed cytomegalovirus (CMV) enteritis which was triggered by therapy-induced leukopenia." | 3.75 | [A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection]. ( Baba, HA; Gerken, G; Kahraman, A; Maldonado-Lopez, E; Miller, M; Treichel, U, 2009) |
| " Here we report the case of a patient with myasthenia gravis receiving long-term immunosuppression with azathioprine and recurrent well-differentiated thymic carcinoma who developed CD4+ T-cell depletion and CNS cryptococcosis after multiple courses of chemotherapy and mediastinal irradiation." | 3.70 | Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis. ( Padberg, F; Schmidt, S, 1998) |
| "6 years after resection and postirradiation of an "asymptomatic" thymoma, myasthenia gravis developed in a 46 year old man which improved within 6 months following initiation of immunosuppressive therapy with azathioprine." | 3.65 | [Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)]. ( Fischer, K; Janzen, RW; Lachenmayer, L, 1977) |
| "Myasthenia gravis is caused by antibodies against acetylcholine receptors and is treated with inhibition or elimination of antibody production." | 2.41 | [A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy]. ( Inoue, Y; Matsuda, O; Takahashi, K; Takemura, T; Yoshimura, A, 2000) |
| "Limbic encephalitis is typically characterised by a sub-acute onset of disorientation, amnesia and seizures, but the clinical spectrum is not yet fully defined and the syndrome could be under-diagnosed." | 1.35 | Hypothermia in VGKC antibody-associated limbic encephalitis. ( Clover, L; Grubneac, A; Irani, SR; Jacob, S; Rajabally, YA; Vincent, A; Walters, RJ; Yazaki, M, 2008) |
| "Only four patients with extrathymic tumors had an associated thymoma." | 1.33 | Extrathymic malignancies in patients with myasthenia gravis. ( Abramsky, O; Argov, Z; Ben Hur, T; Karussis, D; Levin, N; Lossos, A; Siegal, T, 2005) |
| " Remission, pharmacological remission, and marked improvement with reduction in drug dosage were considered good results." | 1.31 | Clinical characteristics and prognosis of myasthenia gravis in older people. ( Batocchi, AP; Di Schino, C; Evoli, A; Minisci, C; Tonali, P, 2000) |
| "Thymoma was more common in the older population; these patients did no worse than the population as a whole." | 1.28 | The relationship of age to outcome in myasthenia gravis. ( Ansher, M; Donaldson, DH; Horan, S; Ringel, SP; Rutherford, RB, 1990) |
| "The thymoma was removed: after the operation no improvement of her anaemic condition was observed and colony growth was very poor, although T-depleted narrow preparations showed a modest BFU-E formation in autologous serum." | 1.27 | Pure red cell aplasia and thymoma: demonstration of persisting inhibition of erythropoiesis after thymectomy and resolution after immune suppressive treatment. ( Dalton, R; Eridani, S; Sawyer, B; Whitehead, S, 1986) |
| "A group of 16 patients with severe generalized myasthenia gravis (MG) (five with thymoma) that was resistant to anticholinesterases, thymectomy, and corticosteroids were treated by plasmapheresis." | 1.26 | Plasmapheresis in refractory generalized myasthenia gravis. ( Ambinder, EP; Bender, AN; Genkins, G; Goldberg, J; Kornfeld, P; Mittag, T; Papatestas, AE, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (44.44) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 4 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, EG | 1 |
| Pottegård, A | 1 |
| Hallas, J | 1 |
| Friis, S | 1 |
| Hansen, K | 1 |
| Jensen, PE | 1 |
| Gaist, D | 1 |
| Benjamin, B | 1 |
| Zaltzman, R | 1 |
| Shpitz, B | 1 |
| Gordon, CR | 1 |
| Avital, S | 1 |
| Modrego, PJ | 1 |
| Arribas, J | 1 |
| Kahraman, A | 1 |
| Miller, M | 1 |
| Maldonado-Lopez, E | 1 |
| Baba, HA | 1 |
| Treichel, U | 1 |
| Gerken, G | 1 |
| Rigamonti, A | 1 |
| Lauria, G | 1 |
| Piamarta, F | 1 |
| Fiumani, A | 1 |
| Agostoni, E | 1 |
| Gogovska, L | 1 |
| Ljapcev, R | 1 |
| Polenakovic, M | 1 |
| Stojkovski, L | 1 |
| Popovska, M | 1 |
| Grcevska, L | 1 |
| Romi, F | 1 |
| Gilhus, NE | 1 |
| Varhaug, JE | 1 |
| Myking, A | 1 |
| Aarli, JA | 1 |
| Levin, N | 1 |
| Abramsky, O | 1 |
| Lossos, A | 1 |
| Karussis, D | 1 |
| Siegal, T | 1 |
| Argov, Z | 1 |
| Ben Hur, T | 1 |
| Ashraf, VV | 1 |
| Taly, AB | 1 |
| Veerendrakumar, M | 1 |
| Rao, S | 1 |
| Jacob, S | 1 |
| Irani, SR | 1 |
| Rajabally, YA | 1 |
| Grubneac, A | 1 |
| Walters, RJ | 1 |
| Yazaki, M | 1 |
| Clover, L | 1 |
| Vincent, A | 1 |
| Schumm, F | 1 |
| Brinkmann, A | 1 |
| Fateh-Moghadam, A | 1 |
| Dau, PC | 1 |
| Kornfeld, P | 1 |
| Ambinder, EP | 1 |
| Mittag, T | 1 |
| Bender, AN | 1 |
| Papatestas, AE | 1 |
| Goldberg, J | 1 |
| Genkins, G | 1 |
| Mukaida, T | 1 |
| Aoe, M | 1 |
| Yamashita, M | 1 |
| Date, H | 1 |
| Ando, A | 1 |
| Shimizu, N | 1 |
| Beekman, R | 1 |
| Kuks, JB | 1 |
| Oosterhuis, HJ | 1 |
| Schmidt, S | 1 |
| Padberg, F | 1 |
| Crawford, WW | 1 |
| Yusin, JS | 1 |
| Klaustermeyer, WB | 1 |
| Takahashi, K | 1 |
| Inoue, Y | 1 |
| Matsuda, O | 1 |
| Takemura, T | 1 |
| Yoshimura, A | 1 |
| Evoli, A | 1 |
| Batocchi, AP | 1 |
| Minisci, C | 1 |
| Di Schino, C | 1 |
| Tonali, P | 1 |
| Janzen, RW | 1 |
| Lachenmayer, L | 1 |
| Fischer, K | 1 |
| Arimori, S | 1 |
| Nakata, Y | 1 |
| Tada, S | 1 |
| Kobashi, H | 1 |
| Koriyama, K | 1 |
| Ichikawa, Y | 1 |
| Mitsuhashi, A | 1 |
| Iwasaki, I | 1 |
| Hiraki, K | 1 |
| Zimmermann, CW | 1 |
| Lingenfelser, T | 1 |
| Melms, A | 1 |
| Jakober, B | 1 |
| Kumagai, M | 1 |
| Kondou, T | 1 |
| Handa, M | 1 |
| Shiraishi, Y | 1 |
| Fujimura, S | 1 |
| Nakata, T | 1 |
| Mathieson, PW | 1 |
| O'Neill, JH | 1 |
| Durrant, ST | 1 |
| Henderson, SJ | 1 |
| Green, PJ | 1 |
| Newsom-Davis, J | 1 |
| Donaldson, DH | 1 |
| Ansher, M | 1 |
| Horan, S | 1 |
| Rutherford, RB | 1 |
| Ringel, SP | 1 |
| Smith, N | 1 |
| Boughton, BJ | 1 |
| Eridani, S | 1 |
| Whitehead, S | 1 |
| Sawyer, B | 1 |
| Dalton, R | 1 |
| Herrmann, C | 1 |
| Lindstrom, JM | 1 |
| Keesey, JC | 1 |
| Mulder, DG | 1 |
| Meier, H | 1 |
| Fox, RR | 1 |
| Casey, TP | 2 |
| Ricken, D | 1 |
| Marmont, A | 1 |
| Gori, E | 1 |
| Doll, R | 1 |
| Kinlen, L | 1 |
| Böttcher, D | 1 |
| Maas, D | 1 |
| Wendt, F | 1 |
| Schubothe, H | 1 |
| Safdar, SH | 1 |
| Krantz, SB | 1 |
| Brown, EB | 1 |
2 reviews available for azathioprine and Thymoma
| Article | Year |
|---|---|
[A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy].
Topics: Azathioprine; Female; Humans; Immunosuppressive Agents; Middle Aged; Myasthenia Gravis; Nephrosis, L | 2000 |
Myasthenia gravis--current concepts.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adult; Animals; Autoantibodies; Autoimmune Diseases; Azathio | 1985 |
34 other studies available for azathioprine and Thymoma
| Article | Year |
|---|---|
Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark.
Topics: Aged; Aged, 80 and over; Azathioprine; Case-Control Studies; Denmark; Female; Humans; Male; Middle A | 2013 |
Presacral Mass Discovered during Pregnancy followed by Myasthenia Gravis.
Topics: Adult; Azathioprine; Castleman Disease; Cholinesterase Inhibitors; Female; Humans; Immunosuppressive | 2015 |
Spontaneous resolution of a mediastinal mass in a woman with myasthenia gravis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azathioprine; Cholinesterase Inhib | 2018 |
[A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection].
Topics: Agammaglobulinemia; Antiviral Agents; Azathioprine; Cidofovir; Colitis, Ulcerative; Cytomegalovirus | 2009 |
Thymoma-associated myasthenia gravis without acetylcholine receptor antibodies.
Topics: Action Potentials; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Electric Stimulation; Evo | 2011 |
Plasmaexchange in the treatment of myasthenia gravis associated with thymoma.
Topics: Adult; Azathioprine; Cholinesterase Inhibitors; Cyclosporine; Female; Glucocorticoids; Humans; Immun | 2003 |
Disease severity and outcome in thymoma myasthenia gravis: a long-term observation study.
Topics: Adrenal Cortex Hormones; Adult; Age of Onset; Autoantibodies; Azathioprine; Combined Modality Therap | 2003 |
Extrathymic malignancies in patients with myasthenia gravis.
Topics: Adult; Age Factors; Age of Onset; Aged; Autoimmune Diseases; Azathioprine; Disease Progression; Fema | 2005 |
Myasthenia gravis in children: a longitudinal study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Distribution; Age of Onset; Azathioprine; Child; Chi | 2006 |
Hypothermia in VGKC antibody-associated limbic encephalitis.
Topics: Aged; Atrophy; Autoantibodies; Azathioprine; Cyclosporine; Dominance, Cerebral; Epilepsy, Temporal L | 2008 |
[Antibody-controlled cytostatic therapy of malignant thymoma with concomitant myasthenia gravis].
Topics: Acetylcholine; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Cyclophosph | 1984 |
The role of plasma exchange in treatment of myasthenia gravis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Autoantibodies; Azathioprine; Female; Humans; Immunoglobulin G | 1982 |
Plasmapheresis in refractory generalized myasthenia gravis.
Topics: Adult; Aged; Antibodies; Azathioprine; Cholinesterases; Female; Humans; Male; Middle Aged; Myastheni | 1981 |
[Four cases of thymoma associated with pure red cell aplasia].
Topics: Adult; Aged; Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged | 1997 |
Myasthenia gravis: diagnosis and follow-up of 100 consecutive patients.
Topics: Age of Onset; Aged; Autoimmune Diseases; Azathioprine; Cholinesterase Inhibitors; Cohort Studies; Di | 1997 |
Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis.
Topics: Adult; Age Factors; Azathioprine; Carcinoma; CD4-Positive T-Lymphocytes; Female; Humans; Immunologic | 1998 |
Nonsurgical regression of thymoma following corticosteroid/azathioprine therapy.
Topics: Adrenal Cortex Hormones; Agammaglobulinemia; Azathioprine; Common Variable Immunodeficiency; Humans; | 1999 |
Clinical characteristics and prognosis of myasthenia gravis in older people.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Cholinesterase Inhibitors; Drug The | 2000 |
[Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)].
Topics: Adult; Antibodies, Antinuclear; Azathioprine; Humans; Male; Middle Aged; Myasthenia Gravis; Pyridost | 1977 |
[A case of thymoma with myasthenia gravis and pure red cell aplasia treated with thymectomy and azathioprine (author's transl)].
Topics: Aged; Anemia, Aplastic; Azathioprine; Humans; Male; Myasthenia Gravis; Thymectomy; Thymoma; Thymus N | 1978 |
[Abscess of the thyroid gland caused by Salmonella enteritidis in immunosuppressive treatment of generalized myasthenia gravis with thymoma].
Topics: Abscess; Aged; Azathioprine; Humans; Middle Aged; Myasthenia Gravis; Opportunistic Infections; Risk | 1990 |
[Treatment of invasive thymoma with myasthenia gravis: a case report responsive to azathioprine and methylprednisolone].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Humans; Male; Methylprednisolone; Myasthenia Gravis; | 1990 |
Antibody-mediated pure neutrophil aplasia, recurrent myasthenia gravis and previous thymoma: case report and literature review.
Topics: Adult; Agranulocytosis; Antibodies; Azathioprine; Bone Marrow; Female; Humans; Immunosuppression The | 1990 |
The relationship of age to outcome in myasthenia gravis.
Topics: Adrenal Cortex Hormones; Aged; Aging; Antibodies; Autoimmune Diseases; Azathioprine; Combined Modali | 1990 |
Azathioprine as possible explanation of etiology of pure red cell aplasia in myasthenics.
Topics: Adult; Azathioprine; Female; Humans; Myasthenia Gravis; Red-Cell Aplasia, Pure; Thymoma | 1989 |
Pure red cell aplasia and thymoma: demonstration of persisting inhibition of erythropoiesis after thymectomy and resolution after immune suppressive treatment.
Topics: Antibody Formation; Azathioprine; Bone Marrow Cells; Colony-Forming Units Assay; Erythropoiesis; Fem | 1986 |
Hereditary lymphosarcoma in WH rabbits and hereditary hemolytic anemia associated with thymoma in strain X rabbits.
Topics: Anemia, Hemolytic; Animals; Antigens, Viral; Azathioprine; Complement Fixation Tests; Culture Techni | 1973 |
Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.
Topics: Albuminuria; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Coombs Test; Glomerulonephritis; | 1968 |
[Current results of the treatment of pseudoparalytic myasthenia gravis with immunosuppressive agents].
Topics: Adrenocorticotropic Hormone; Adult; Antibodies; Antilymphocyte Serum; Azathioprine; Cholinesterase I | 1972 |
[Pure erythroblastic aplasia associated with thymoma in an adult. Complete remission after immunodepressive therapy].
Topics: Anemia, Aplastic; Azathioprine; Cyclophosphamide; Hemangiosarcoma; Humans; Immunosuppressive Agents; | 1973 |
Immunosurveillance and cancer: epidemiological evidence.
Topics: Adolescent; Adult; Age Factors; Aged; Azathioprine; Chediak-Higashi Syndrome; Child; Child, Preschoo | 1970 |
[Anemia caused by erythroblastopenia in adult age].
Topics: Aged; Analgesics; Anemia, Aplastic; Azathioprine; Blood Transfusion; Female; Heart Failure; Hepatiti | 1970 |
Successful immunosuppressive treatment of erythroid aplasia appearing after thymectomy.
Topics: Anemia, Aplastic; Antibodies, Antinuclear; Azathioprine; Bone Marrow; Cyclophosphamide; Erythropoies | 1970 |
The development of lymphomas in mice with autoimmune disorders treated with azathioprine.
Topics: Animals; Autoimmune Diseases; Azathioprine; Female; Injections, Intramuscular; Lupus Erythematosus, | 1968 |