azathioprine has been researched along with Thrombopenia in 110 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A prospective randomized trial in patients with Crohn disease studied whether 6-thioguanine nucleotide (6-TGN) concentration-adapted azathioprine (AZA) therapy is clinically superior to a standard dose of 2." | 9.12 | 6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial. ( Adler, G; Armstrong, VW; Behrens, C; Bias, P; Herfarth, H; Kruis, W; Oellerich, M; Reinshagen, M; Schütz, E; Shipkova, M; Stallmach, A; Stein, J; von Ahsen, N; von Tirpitz, C, 2007) |
| "Azathioprine (AZA) is commonly used for many autoimmune disorders; however, the limitation of its clinical use is due to potential toxicities, including severe leukopenia." | 8.12 | Implementation of NUDT15 Genotyping to Prevent Azathioprine-Induced Leukopenia for Patients With Autoimmune Disorders in Chinese Population. ( Chang, CJ; Chang, YC; Chang, YT; Chen, CB; Chen, HC; Chen, WT; Chi, MH; Chung, WH; Huang, PW; Huang, YH; Hui, RC; Jan Wu, YJ; Kao, HW; Lin, YJ; Lu, CW; Ng, CY; Tsai, TF; Wang, CW; Yu, KH, 2022) |
| "We report the occurrence of scleroderma and autoimmune thrombocytopenia in a patient who took L-tryptophan as a muscle-building adjuvant." | 7.68 | Scleroderma and autoimmune thrombocytopenia associated with ingestion of L-tryptophan. ( Adams, SJ; Morgan, JM, 1993) |
| "Azathioprine, a thiopurine antimetabolite used in the treatment of immune-mediated thrombocytopenia in human beings and dogs, was used in 2 cases of immune-mediated thrombocytopenia in horses that failed to respond to corticosteroid therapy alone." | 7.68 | Azathioprine for treatment of immune-mediated thrombocytopenia in two horses. ( Beech, J; Cudd, TA; Gardner, SY; Humber, KA; Palmer, JE; Sommer, MM, 1991) |
| "danazol appears to be a useful adjunctive treatment for refractory autoimmune thrombocytopenia associated with systemic lupus erythematosus." | 7.67 | Danazol for the treatment of refractory autoimmune thrombocytopenia in systemic lupus erythematosus. ( Johnson, SC; West, SG, 1988) |
| "Azathioprine treatment benefited 19 (66%) out of 29 patients suffering from severe psoriasis." | 7.65 | Treatment of psoriasis with azathioprine. ( Du Vivier, A; Munro, DD; Verbov, J, 1974) |
| "Treatment with prednisone alone results in fewer infections and better survival than prednisone and azathioprine in standard-risk chronic GVHD." | 6.66 | Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation. ( Appelbaum, FR; Dahlberg, S; Deeg, HJ; Doney, KC; Flournoy, N; Sanders, JE; Storb, R; Sullivan, KM; Weiden, P; Witherspoon, RP, 1988) |
| "Antinuclear antibody (ANA)-positive immune thrombocytopenia (ITP) patients have an unsatisfactory prognosis due to the more severe conditions of these patients and poor response to first-line glucocorticoids (GCs)." | 5.91 | Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study. ( Chen, X; Dong, Z; Ma, L; Su, J; Wang, Q; Xiao, P; Xu, M, 2023) |
| "Azathioprine treatment for AAMT is low risk, convenient, and cost-effective." | 5.37 | Successful treatment of amegakaryocytic thrombocytopenia with azathioprine. ( Chang, H; Tang, TC, 2011) |
| "Neutropenia was ameliorated with use of granulocyte colony-stimulating factor." | 5.37 | Infliximab- and azathioprine-related severe neutropenia and thrombocytopenia in a case with Crohn's disease. ( Alkim, C; Alkim, H; Altinkaya, E; Boğa, S; Buğdaci, MS; Köksal, AR; Özdoğan, O; Sökmen, M, 2011) |
| "A prospective randomized trial in patients with Crohn disease studied whether 6-thioguanine nucleotide (6-TGN) concentration-adapted azathioprine (AZA) therapy is clinically superior to a standard dose of 2." | 5.12 | 6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial. ( Adler, G; Armstrong, VW; Behrens, C; Bias, P; Herfarth, H; Kruis, W; Oellerich, M; Reinshagen, M; Schütz, E; Shipkova, M; Stallmach, A; Stein, J; von Ahsen, N; von Tirpitz, C, 2007) |
| "Azathioprine (AZA) is commonly used for many autoimmune disorders; however, the limitation of its clinical use is due to potential toxicities, including severe leukopenia." | 4.12 | Implementation of NUDT15 Genotyping to Prevent Azathioprine-Induced Leukopenia for Patients With Autoimmune Disorders in Chinese Population. ( Chang, CJ; Chang, YC; Chang, YT; Chen, CB; Chen, HC; Chen, WT; Chi, MH; Chung, WH; Huang, PW; Huang, YH; Hui, RC; Jan Wu, YJ; Kao, HW; Lin, YJ; Lu, CW; Ng, CY; Tsai, TF; Wang, CW; Yu, KH, 2022) |
| " In univariate analysis, older age at PM/DM onset, anemia, thrombocytopenia, leukopenia, diabetes mellitus, ILD, cancer, and non-use of azathioprine were associated with higher mortality (p = 0." | 3.77 | Survival analysis of patients with dermatomyositis and polymyositis: analysis of 192 Chinese cases. ( Chang, HC; Chen, IJ; Ho, HH; Kuo, CF; Luo, SF; See, LC; Shen, YM; Wu, YJ; Yu, KH, 2011) |
| " They developed leukopenia or thrombocytopenia during azathioprine or 6-mercaptopurine treatment." | 3.70 | Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy. ( Bonaz, B; Broly, F; Catala, P; Colombel, JF; Debuysere, H; Ferrari, N; Gendre, JP; Libersa, C; Marteau, P; Modigliani, R; Soulé, JC; Touze, Y, 2000) |
| " Both patients had been treated with azathioprine and prednisolone for 6 years and 4 months and for 4 years and 7 months, respectively, and presented with splenomegaly and thrombocytopenia suggesting hypersplenism." | 3.69 | Idiopathic portal hypertension in renal transplant recipients: report of two cases. ( Kobashi, T; Kohnosu, H; Ohmori, Y; Oka, T; Yasumura, T; Yoshimura, N, 1994) |
| "Azathioprine, a thiopurine antimetabolite used in the treatment of immune-mediated thrombocytopenia in human beings and dogs, was used in 2 cases of immune-mediated thrombocytopenia in horses that failed to respond to corticosteroid therapy alone." | 3.68 | Azathioprine for treatment of immune-mediated thrombocytopenia in two horses. ( Beech, J; Cudd, TA; Gardner, SY; Humber, KA; Palmer, JE; Sommer, MM, 1991) |
| "We report the occurrence of scleroderma and autoimmune thrombocytopenia in a patient who took L-tryptophan as a muscle-building adjuvant." | 3.68 | Scleroderma and autoimmune thrombocytopenia associated with ingestion of L-tryptophan. ( Adams, SJ; Morgan, JM, 1993) |
| "danazol appears to be a useful adjunctive treatment for refractory autoimmune thrombocytopenia associated with systemic lupus erythematosus." | 3.67 | Danazol for the treatment of refractory autoimmune thrombocytopenia in systemic lupus erythematosus. ( Johnson, SC; West, SG, 1988) |
| "Azathioprine treatment benefited 19 (66%) out of 29 patients suffering from severe psoriasis." | 3.65 | Treatment of psoriasis with azathioprine. ( Du Vivier, A; Munro, DD; Verbov, J, 1974) |
| "Treatment with prednisone alone results in fewer infections and better survival than prednisone and azathioprine in standard-risk chronic GVHD." | 2.66 | Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation. ( Appelbaum, FR; Dahlberg, S; Deeg, HJ; Doney, KC; Flournoy, N; Sanders, JE; Storb, R; Sullivan, KM; Weiden, P; Witherspoon, RP, 1988) |
| "Azathioprine (AZA) is a purine analogue which has been used in the treatment of multiple sclerosis (MS) for over 30 years." | 2.46 | [Oral cladribine for relapsing-remitting multiple sclerosis: another purine analogue or a genuine therapeutic innovation?]. ( Schmidt, S, 2010) |
| "Antinuclear antibody (ANA)-positive immune thrombocytopenia (ITP) patients have an unsatisfactory prognosis due to the more severe conditions of these patients and poor response to first-line glucocorticoids (GCs)." | 1.91 | Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study. ( Chen, X; Dong, Z; Ma, L; Su, J; Wang, Q; Xiao, P; Xu, M, 2023) |
| " Medications included chronic use of prednisone, methotrexate, abatacept, cyclophosphamide, mycophenolate mofetil, rituximab, tofacitinib, and sildenafil." | 1.72 | Nodular Regenerative Hyperplasia of the liver in Juvenile Dermatomyositis. ( Heller, T; Kleiner, DE; Lanis, A; Rider, LG; Shenoi, S; Vittal, A; Volochayev, R, 2022) |
| "Treatment of thrombocytopenia in systemic lupus erythematosus (SLE) is considered in cases of current bleeding, severe bruising, or a platelet count below 50,000/µL." | 1.39 | Two cases of refractory thrombocytopenia in systemic lupus erythematosus that responded to intravenous low-dose cyclophosphamide. ( Chung, SJ; Kang, MI; Kang, Y; Lee, SK; Lee, SW; Park, HJ; Park, YB, 2013) |
| "Neutropenia was ameliorated with use of granulocyte colony-stimulating factor." | 1.37 | Infliximab- and azathioprine-related severe neutropenia and thrombocytopenia in a case with Crohn's disease. ( Alkim, C; Alkim, H; Altinkaya, E; Boğa, S; Buğdaci, MS; Köksal, AR; Özdoğan, O; Sökmen, M, 2011) |
| "Azathioprine treatment for AAMT is low risk, convenient, and cost-effective." | 1.37 | Successful treatment of amegakaryocytic thrombocytopenia with azathioprine. ( Chang, H; Tang, TC, 2011) |
| "Two patients developed acute pancreatitis." | 1.34 | Thiopurine metabolite monitoring in paediatric inflammatory bowel disease. ( Bohane, TD; Day, AS; Lee, D; Naidoo, D; Ooi, CY, 2007) |
| "The diagnostic criteria for systemic lupus erythematosus (SLE) were not fulfilled either." | 1.32 | Late puerperal thrombohemorrhagic complications in a patient with antiphospholipid syndrome. ( Bladt, V; d'Amore, F; Laursen, B; Petersen, OB; Poulsen, LH; Steengaard-Pedersen, K, 2004) |
| " Before thiopurine dosage adjustments, TPMT-deficient patients experienced more frequent hospitalization, more platelet transfusions, and more missed doses of chemotherapy." | 1.31 | Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. ( Bomgaars, L; Coutre, S; Evans, WE; Holdsworth, M; Hon, YY; Janco, R; Kalwinsky, D; Keller, F; Khatib, Z; Kornegay, N; Krynetski, EY; Margolin, J; Murray, J; Quinn, J; Ravindranath, Y; Relling, MV; Ritchey, K; Roberts, W; Rogers, ZR; Schiff, D; Steuber, C; Tucci, F, 2001) |
| "(4) Sirolimus has numerous adverse effects, including hyperlipidemia, thrombocytopenia, hepatic disorders and opportunistic infections." | 1.31 | Sirolimus: new preparation. No tangible advance in renal transplantation. ( , 2002) |
| "One dog developed lymphocytic thyroiditis and serum antinuclear antibody at day 691 after initial presentation, and two cases developed disease consistent with autoimmune thrombocytopenia (AITP) at 365 and 618 days post initial presentation." | 1.29 | Serial monitoring of clinical, haematological and immunological parameters in canine autoimmune haemolytic anaemia. ( Day, MJ, 1996) |
| "Isolated thrombocytopenia was never clinically severe." | 1.29 | Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience. ( Connell, WR; Kamm, MA; Lennard-Jones, JE; Ritchie, JK, 1993) |
| "Azathioprine treatment played only a minor role in the development of thrombocytopenia but patients with low (100-200 mio." | 1.29 | Bone marrow function during quadruple immunosuppressive therapy after renal transplantation. ( Heaf, J, 1993) |
| " Four weeks after discontinuation of azathioprine, 1 treated cat again was given azathioprine at a lower dosage (1." | 1.28 | Systemic toxicosis associated with azathioprine administration in domestic cats. ( Altman, D; Beale, KM; Bolon, B; Clemmons, RR, 1992) |
| "Prednisone was administered to 134 patients (90 per cent) in whom a peak platelet count occurred at a median of eight days, at which time four distinct patterns of response became evident: 20 patients (15 per cent) achieved complete remission with platelet counts greater than 200 X 10(9)/I, and of these 13 relapsed; 46 (34 per cent) had incomplete remission with platelet counts between 100 and 200 X 10(9)/I, and of these 38 relapsed; 22 (17 per cent) had a partial remission with platelet counts between 50 and 100 X 10(9)/I, and 14 have relapsed; the remaining 46 (34 per cent) failed to respond to prednisone." | 1.27 | Results of treatment in immune thrombocytopenia. ( Dent, DM; Jacobs, P; Wood, L, 1986) |
| "Fourteen patients with systemic lupus erythematosus had splenectomies done between 1960 and 1982 for treatment of severe thrombocytopenia." | 1.27 | Splenectomy does not cure the thrombocytopenia of systemic lupus erythematosus. ( Greipp, PR; Hall, S; McCormick, JL; McKenna, CH; Michet, CJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (55.45) | 18.7374 |
| 1990's | 14 (12.73) | 18.2507 |
| 2000's | 15 (13.64) | 29.6817 |
| 2010's | 17 (15.45) | 24.3611 |
| 2020's | 3 (2.73) | 2.80 |
| Authors | Studies |
|---|---|
| Lanis, A | 1 |
| Volochayev, R | 1 |
| Kleiner, DE | 1 |
| Vittal, A | 1 |
| Heller, T | 1 |
| Rider, LG | 1 |
| Shenoi, S | 1 |
| Wang, CW | 1 |
| Chi, MH | 1 |
| Tsai, TF | 1 |
| Yu, KH | 2 |
| Kao, HW | 1 |
| Chen, HC | 1 |
| Chen, CB | 1 |
| Lu, CW | 1 |
| Chen, WT | 1 |
| Chang, YC | 1 |
| Chang, CJ | 2 |
| Chang, YT | 1 |
| Jan Wu, YJ | 1 |
| Huang, YH | 1 |
| Ng, CY | 1 |
| Huang, PW | 1 |
| Lin, YJ | 1 |
| Hui, RC | 1 |
| Chung, WH | 1 |
| Su, J | 1 |
| Xu, M | 1 |
| Dong, Z | 1 |
| Wang, Q | 1 |
| Ma, L | 1 |
| Xiao, P | 1 |
| Chen, X | 1 |
| Park, HJ | 1 |
| Kang, MI | 1 |
| Kang, Y | 1 |
| Chung, SJ | 1 |
| Lee, SW | 1 |
| Park, YB | 1 |
| Lee, SK | 1 |
| Ahmed, WM | 1 |
| Khalaf, AA | 1 |
| Moselhy, WA | 1 |
| Safwat, GM | 1 |
| Bain, BJ | 1 |
| Weiler, S | 1 |
| Aellig, N | 1 |
| Fauchère, I | 1 |
| Jetter, A | 1 |
| Corti, N | 1 |
| Goh, KG | 1 |
| Ong, SG | 1 |
| Coenen, MJ | 1 |
| de Jong, DJ | 1 |
| van Marrewijk, CJ | 1 |
| Derijks, LJ | 1 |
| Vermeulen, SH | 1 |
| Wong, DR | 1 |
| Klungel, OH | 1 |
| Verbeek, AL | 1 |
| Hooymans, PM | 1 |
| Peters, WH | 1 |
| te Morsche, RH | 1 |
| Newman, WG | 1 |
| Scheffer, H | 1 |
| Guchelaar, HJ | 1 |
| Franke, B | 1 |
| Sanderson, JD | 1 |
| Hsu, WY | 1 |
| Chiou, SS | 1 |
| Liao, YM | 1 |
| Shu, HL | 1 |
| Zeng, YS | 1 |
| Wong, CC | 1 |
| Lin, PC | 1 |
| González-Naranjo, LA | 1 |
| Betancur, OM | 1 |
| Alarcón, GS | 1 |
| Ugarte-Gil, MF | 1 |
| Jaramillo-Arroyave, D | 1 |
| Wojdyla, D | 1 |
| Pons-Estel, GJ | 1 |
| Rondón-Herrera, F | 1 |
| Vásquez-Duque, GM | 1 |
| Quintana-López, G | 1 |
| Da Silva, NA | 1 |
| Tavares Brenol, JC | 1 |
| Reyes-Llerena, G | 1 |
| Pascual-Ramos, V | 1 |
| Amigo, MC | 1 |
| Massardo, L | 1 |
| Alfaro-Lozano, J | 1 |
| Segami, MI | 1 |
| Esteva-Spinetti, MH | 1 |
| Iglesias-Gamarra, A | 1 |
| Pons-Estel, BA | 1 |
| Goggs, R | 1 |
| Boag, AK | 1 |
| Chan, DL | 1 |
| Lewis, JD | 1 |
| Abramson, O | 1 |
| Pascua, M | 1 |
| Liu, L | 1 |
| Asakura, LM | 1 |
| Velayos, FS | 1 |
| Hutfless, SM | 1 |
| Alison, JE | 1 |
| Herrinton, LJ | 1 |
| Schmidt, S | 1 |
| Salama, A | 1 |
| Levine, AB | 1 |
| Erkan, D | 1 |
| Chang, H | 1 |
| Tang, TC | 1 |
| Wu, YJ | 1 |
| Kuo, CF | 1 |
| See, LC | 1 |
| Shen, YM | 1 |
| Chang, HC | 1 |
| Luo, SF | 1 |
| Ho, HH | 1 |
| Chen, IJ | 1 |
| Jung, KD | 1 |
| Kim, PS | 1 |
| Park, HY | 1 |
| Kim, CR | 1 |
| Byun, JY | 1 |
| Lee, DY | 1 |
| Lee, JH | 1 |
| Yang, JM | 1 |
| Lee, ES | 1 |
| Dircks, B | 1 |
| Schuberth, HJ | 1 |
| Mischke, R | 1 |
| Köksal, AR | 1 |
| Alkim, C | 1 |
| Altinkaya, E | 1 |
| Buğdaci, MS | 1 |
| Özdoğan, O | 1 |
| Boğa, S | 1 |
| Alkim, H | 1 |
| Sökmen, M | 1 |
| Thomas, RV | 1 |
| Bessos, H | 1 |
| Turner, ML | 1 |
| Horn, EH | 1 |
| Ludlam, CA | 1 |
| Aviña-Zubieta, JA | 1 |
| Galindo-Rodrìguez, G | 1 |
| Robledo, I | 1 |
| Vela-Ojeda, J | 1 |
| Vadillo-Buenfil, M | 1 |
| Rosas-Cabral, A | 1 |
| Salazar-Exaire, D | 1 |
| Ucci, G | 1 |
| Ferrando, P | 1 |
| Valentini, D | 1 |
| Zavallone, L | 1 |
| RICHMOND, J | 1 |
| WOODRUFF, MF | 1 |
| CUMMING, RA | 1 |
| DONALD, KW | 1 |
| McGurrin, MK | 1 |
| Arroyo, LG | 1 |
| Bienzle, D | 1 |
| Buchheidt, D | 1 |
| Hummel, M | 1 |
| Diehl, S | 1 |
| Hehlmann, R | 1 |
| Bladt, V | 1 |
| Steengaard-Pedersen, K | 1 |
| Poulsen, LH | 1 |
| Petersen, OB | 1 |
| Laursen, B | 1 |
| d'Amore, F | 1 |
| Tamori, A | 1 |
| Shinzaki, M | 1 |
| Kosaka, S | 1 |
| Hayashi, T | 1 |
| Iwai, S | 1 |
| Enomoto, M | 1 |
| Habu, D | 1 |
| Sakaguchi, H | 1 |
| Kawada, N | 1 |
| Hino, M | 1 |
| Shiomi, S | 1 |
| Nishiguchi, S | 1 |
| Ooi, CY | 1 |
| Bohane, TD | 1 |
| Lee, D | 1 |
| Naidoo, D | 1 |
| Day, AS | 1 |
| Mosca, M | 1 |
| Tani, C | 1 |
| Bombardieri, S | 1 |
| Rubin, L | 1 |
| Urowitz, MB | 1 |
| Pruzanski, W | 1 |
| Hauer, RW | 1 |
| Möller, B | 1 |
| Malchus, R | 1 |
| Hopf, U | 1 |
| Bradley, PP | 1 |
| Warden, GD | 1 |
| Maxwell, JG | 1 |
| Rothstein, G | 1 |
| Mulshine, J | 1 |
| Lucas, FV | 1 |
| Clough, JD | 1 |
| Kopec, I | 1 |
| Słomkowski, M | 1 |
| Puzyna, W | 1 |
| Maslanka, K | 1 |
| Maj, S | 2 |
| Yoshimura, N | 1 |
| Oka, T | 1 |
| Ohmori, Y | 1 |
| Yasumura, T | 1 |
| Kohnosu, H | 1 |
| Kobashi, T | 1 |
| Najean, Y | 1 |
| Rain, JD | 1 |
| Connell, WR | 1 |
| Kamm, MA | 1 |
| Ritchie, JK | 1 |
| Lennard-Jones, JE | 1 |
| Heaf, J | 1 |
| Morgan, JM | 1 |
| Adams, SJ | 1 |
| Rinkardt, NE | 1 |
| Kruth, SA | 1 |
| Day, MJ | 1 |
| Colombel, JF | 1 |
| Ferrari, N | 1 |
| Debuysere, H | 1 |
| Marteau, P | 1 |
| Gendre, JP | 1 |
| Bonaz, B | 1 |
| Soulé, JC | 1 |
| Modigliani, R | 1 |
| Touze, Y | 1 |
| Catala, P | 1 |
| Libersa, C | 1 |
| Broly, F | 1 |
| Evans, WE | 1 |
| Hon, YY | 1 |
| Bomgaars, L | 1 |
| Coutre, S | 1 |
| Holdsworth, M | 1 |
| Janco, R | 1 |
| Kalwinsky, D | 1 |
| Keller, F | 1 |
| Khatib, Z | 1 |
| Margolin, J | 1 |
| Murray, J | 1 |
| Quinn, J | 1 |
| Ravindranath, Y | 1 |
| Ritchey, K | 1 |
| Roberts, W | 1 |
| Rogers, ZR | 1 |
| Schiff, D | 1 |
| Steuber, C | 1 |
| Tucci, F | 1 |
| Kornegay, N | 1 |
| Krynetski, EY | 1 |
| Relling, MV | 1 |
| Landis, TF | 1 |
| von Felten, A | 1 |
| Berchtold, H | 1 |
| Hill, HF | 1 |
| Braun, HH | 1 |
| Henning, H | 1 |
| Probst, P | 1 |
| Kaplan, BS | 1 |
| Chassot, PG | 1 |
| Knaack, J | 1 |
| Morehouse, D | 1 |
| Beaudoin, JG | 1 |
| Guttmann, RD | 1 |
| Bzowy, B | 1 |
| Wermut, W | 1 |
| Chintu, C | 1 |
| McClure, P | 1 |
| Boratyńska, M | 1 |
| Szepietowski, T | 1 |
| Szewczyk, Z | 1 |
| Szydłowski, Z | 1 |
| Beale, KM | 1 |
| Altman, D | 1 |
| Clemmons, RR | 1 |
| Bolon, B | 1 |
| Humber, KA | 1 |
| Beech, J | 1 |
| Cudd, TA | 1 |
| Palmer, JE | 1 |
| Gardner, SY | 1 |
| Sommer, MM | 1 |
| Amore, M | 1 |
| Montanari, M | 1 |
| Cerisoli, M | 1 |
| Dan, K | 1 |
| Inokuchi, K | 1 |
| An, E | 1 |
| Nomura, T | 1 |
| DeJong, DJ | 1 |
| Sayler, DJ | 1 |
| Sullivan, KM | 1 |
| Witherspoon, RP | 1 |
| Storb, R | 1 |
| Weiden, P | 1 |
| Flournoy, N | 1 |
| Dahlberg, S | 1 |
| Deeg, HJ | 1 |
| Sanders, JE | 1 |
| Doney, KC | 1 |
| Appelbaum, FR | 1 |
| García Buey, L | 1 |
| Moreno Otero, R | 1 |
| García Sánchez, A | 1 |
| González Estecha, A | 1 |
| Pajares, JM | 1 |
| West, SG | 1 |
| Johnson, SC | 1 |
| Jacobs, P | 1 |
| Wood, L | 1 |
| Dent, DM | 1 |
| First, LR | 1 |
| Smith, BR | 1 |
| Lipton, J | 1 |
| Nathan, DG | 1 |
| Parkman, R | 1 |
| Rappeport, JM | 1 |
| Hall, S | 1 |
| McCormick, JL | 1 |
| Greipp, PR | 1 |
| Michet, CJ | 1 |
| McKenna, CH | 1 |
| Magyar, I | 2 |
| Kovacs, A | 1 |
| Sheil, AG | 1 |
| Mears, D | 1 |
| Kelly, GE | 1 |
| Stewart, JH | 1 |
| Johnson, JR | 1 |
| Tiller, D | 1 |
| Gallery, ED | 1 |
| Duggin, GG | 1 |
| Lorenzen, I | 1 |
| Brun, C | 1 |
| Videbaek, A | 1 |
| Mee, AD | 1 |
| Evans, DB | 1 |
| Goebel, KM | 1 |
| Goebel, FD | 1 |
| Gassel, WD | 1 |
| Mueller, K | 1 |
| Scheiffarth, F | 1 |
| Warnatz, H | 1 |
| Sánchez-Fayos, J | 2 |
| Outeirino, J | 1 |
| Serrano, J | 1 |
| Calabuig, MT | 1 |
| Paniagua, G | 1 |
| Cooper, MR | 1 |
| Hansen, KS | 1 |
| Maynard, CD | 1 |
| Elrod, IW | 1 |
| Spurr, CL | 1 |
| Gynn, TN | 1 |
| Messmore, HL | 1 |
| Friedman, IA | 1 |
| Brodehl, J | 1 |
| Rhodes, J | 1 |
| Wallnöfer, H | 1 |
| Hanusch, M | 1 |
| Ku, G | 1 |
| Varghese, Z | 1 |
| Fernando, ON | 1 |
| Baillod, R | 1 |
| Hopewell, JP | 1 |
| Moorhead, JF | 1 |
| George, CR | 1 |
| Tremann, JA | 1 |
| Quadracci, LJ | 1 |
| Striker, GE | 1 |
| Marchioro, TL | 1 |
| Breidenbach, H | 1 |
| Krosse, C | 1 |
| Schuster, W | 1 |
| Potel, S | 1 |
| Seyfried, H | 1 |
| Górska, B | 1 |
| Sylwestrowicz, T | 1 |
| Giles, CM | 1 |
| Goldsmith, KL | 1 |
| Miescher, PA | 1 |
| Dale, I | 1 |
| Aberg, H | 1 |
| Levander, H | 1 |
| Westerberg, KE | 1 |
| Du Vivier, A | 1 |
| Munro, DD | 1 |
| Verbov, J | 1 |
| Leiba, H | 1 |
| Wasuki, R | 1 |
| Ahn, YS | 1 |
| Harrington, WJ | 1 |
| Seelman, RC | 1 |
| Eytel, CS | 1 |
| Keitel, W | 1 |
| Kleine, FD | 1 |
| Werner, R | 1 |
| Lichtman, MA | 1 |
| Hoyer, LW | 1 |
| Sears, DA | 1 |
| Woodruff, M | 1 |
| Deodhar, SD | 1 |
| Konomi, K | 1 |
| Nakamoto, S | 1 |
| Kuruvila, KC | 1 |
| Dormont, J | 1 |
| Schwarzenberg, L | 1 |
| Ikkala, E | 1 |
| Suhonen, O | 1 |
| Baserga, A | 1 |
| Stieglitz, R | 1 |
| Nelius, D | 1 |
| Stobbe, H | 1 |
| Baer, I | 1 |
| Schumacher, K | 1 |
| Hoensch, H | 1 |
| Hartwich, G | 1 |
| Schott, G | 1 |
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| Schulz, K | 1 |
| Preussner, S | 1 |
| Frick, G | 1 |
| Kämpfen, P | 1 |
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| Vandenbroucke, J | 1 |
| Schwenke, H | 1 |
| Helbig, W | 1 |
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| Dietrich, M | 1 |
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| Winckelmann, G | 1 |
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| von Ahsen, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacogenetic Testing in the Clinical Setting: is Screening for TPMT Genotype a Cost-effective Treatment Strategy? - The First Prospective Randomized Controlled Trial Within the Dutch Health Care System.[NCT00521950] | 853 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
| Cyclophosphamide and Hydroxychloroquine for the Treatment of Severe Thrombocytopenia in Systemic Lupus Erythematosus[NCT02444728] | Phase 3 | 50 participants (Actual) | Interventional | 2015-07-31 | Terminated (stopped due to Because of insufficient enrollement) | ||
| Phase II Trial of Belumosudil and Rituximab for the Primary Treatment of Extensive Chronic Graft-versus-host Disease[NCT06046248] | Phase 2 | 25 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| Azacitidine (AZA) Combined With N-Acetyl-L-cysteine (NAC) for Prolonged Isolated Thrombocytopenia (PIT) After Hematopoietic Stem Cell Transplantation (HSCT)[NCT05126004] | Phase 2 | 100 participants (Anticipated) | Interventional | 2021-12-01 | Not yet recruiting | ||
| A Prospective Study of Patients With Isolated Thrombocytopenia Following Hematopoietic Stem Cell Transplantation[NCT02487563] | Phase 3 | 97 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The total number of megakaryocytes as well as the platelet-shedding megakaryocytes of bone marrow smears (per cm2) was counted and cross-checked by blinded observers. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment
| Intervention | cells/cm^2 (Median) |
|---|---|
| Experimental Group 1 | 6.7 |
| Experimental Group 2 | 7.5 |
| Control Group | 3.3 |
Platelet response refers to a sustained increase (stable or increasing level) of at least 30×10E9/L independent of transfusion for 3 days. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| Experimental Group 1 | 20 |
| Experimental Group 2 | 22 |
| Control Group | 6 |
10 reviews available for azathioprine and Thrombopenia
| Article | Year |
|---|---|
[Oral cladribine for relapsing-remitting multiple sclerosis: another purine analogue or a genuine therapeutic innovation?].
Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Animals; Azathioprine; Cladribine; Cl | 2010 |
Current treatment options for primary immune thrombocytopenia.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Azathioprine; Benzoates; Humans; Hydr | 2011 |
Clinical assessment and management of cytopenias in lupus patients.
Topics: Anemia; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Glucocorticoids; Humans; Immunoglobuli | 2011 |
A case of undifferentiated connective tissue disease: is it a distinct clinical entity?
Topics: Adrenal Cortex Hormones; Adult; Antimalarials; Antirheumatic Agents; Azathioprine; Diagnosis, Differ | 2008 |
[Liver disease caused by azathioprine: clinical case and review of the literature].
Topics: Aged; Azathioprine; Chemical and Drug Induced Liver Injury; Humans; Leukopenia; Liver Diseases; Male | 1988 |
[Long-term therapy of immunologic diseases with special reference to the use of immunosuppressive agents].
Topics: Adrenocorticotropic Hormone; Alkylating Agents; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents | 1969 |
Drug-induced thrombocytopenia.
Topics: Aged; Agglutination Tests; Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Anticonvulsants; Ant | 1972 |
[Immunosuppressive therapy of the nephrotic syndrome in childhood].
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Cystitis; Drug Resistance; Humans; Immunosuppre | 1972 |
[Pathophysiology of immunological processes. 3. Therapeutic influencing].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Antibody Formation; Antigen-Antibody Reactions; Arthritis, Rheu | 1968 |
Immunosuppression and its complications.
Topics: Adrenal Cortex Hormones; Adult; Animals; Antibody Formation; Antigens; Antilymphocyte Serum; Autoimm | 1969 |
7 trials available for azathioprine and Thrombopenia
| Article | Year |
|---|---|
Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Dosage Calcu | 2015 |
Treatment of rheumatoid arthritis with penicillamine.
Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dru | 1977 |
Prednisone and azathioprine compared with prednisone and placebo for treatment of chronic graft-v-host disease: prognostic influence of prolonged thrombocytopenia after allogeneic marrow transplantation.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Child; Child, Preschool; Chronic Disea | 1988 |
Azathioprine in the treatment of Crohn's disease.
Topics: Azathioprine; Clinical Trials as Topic; Colic; Crohn Disease; Humans; Leukopenia; Lymphoma; Placebos | 1972 |
[Treatment of chronic hepatitis with immunosuppressive agents and D-penicillamine].
Topics: Agranulocytosis; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Hypersensitivity; Fem | 1973 |
Clinical experience with antilymphocyte globulin (ALG) in renal transplantation.
Topics: Anaphylaxis; Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Drug Synergism; Graft Rej | 1971 |
6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Crohn Disease; Dose-Response Relati | 2007 |
93 other studies available for azathioprine and Thrombopenia
| Article | Year |
|---|---|
Nodular Regenerative Hyperplasia of the liver in Juvenile Dermatomyositis.
Topics: Abatacept; Adolescent; Arthritis; Autoantibodies; Azathioprine; Calcinosis; Child; Cyclophosphamide; | 2022 |
Implementation of NUDT15 Genotyping to Prevent Azathioprine-Induced Leukopenia for Patients With Autoimmune Disorders in Chinese Population.
Topics: Autoimmune Diseases; Azathioprine; Genotype; Humans; Immunosuppressive Agents; Leukopenia; Methyltra | 2022 |
Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study.
Topics: Antibodies, Antinuclear; Azathioprine; Humans; Immunosuppressive Agents; Prednisone; Purpura, Thromb | 2023 |
Two cases of refractory thrombocytopenia in systemic lupus erythematosus that responded to intravenous low-dose cyclophosphamide.
Topics: Azathioprine; Bone Marrow; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Immunosuppre | 2013 |
Royal jelly attenuates azathioprine induced toxicity in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Anemia; Animals; Antimetabolites, Antineoplastic; Aspart | 2014 |
Prominent Howell-Jolly bodies when megaloblastic anemia develops in a hyposplenic patient.
Topics: Anemia, Hemolytic, Autoimmune; Anemia, Megaloblastic; Azathioprine; Erythrocyte Inclusions; Female; | 2014 |
Treatment of gout in a renal transplant patient leading to severe thrombocytopenia.
Topics: Aged; Allopurinol; Azathioprine; Diagnosis, Differential; Female; Gout; Gout Suppressants; Humans; I | 2014 |
Recurrent spontaneous subdural hematoma secondary to immune thrombocytopenia in a patient with overlap syndrome.
Topics: Anti-Inflammatory Agents; Azathioprine; Cyclophosphamide; Female; Hematoma, Subdural; Humans; Immuno | 2015 |
TPMT Testing Before Starting Azathioprine or Mercaptopurine: Surely Just Do It?
Topics: Anti-Inflammatory Agents; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female; Gastrointestinal | 2015 |
Successful management of multilineage autoimmune cytopenia complicated with severe infection and deep vein thrombosis in a patient with Hodgkin lymphoma post-autologous hematopoietic stem cell transplantation.
Topics: Adolescent; Autoimmune Diseases; Azathioprine; Bone Marrow Transplantation; Cell Lineage; Cyclophosp | 2016 |
Features associated with hematologic abnormalities and their impact in patients with systemic lupus erythematosus: Data from a multiethnic Latin American cohort.
Topics: Adolescent; Adult; Age Factors; Anemia, Hemolytic; Antibodies, Antinuclear; Antibodies, Antiphosphol | 2016 |
Concurrent immune-mediated haemolytic anaemia and severe thrombocytopenia in 21 dogs.
Topics: Anemia, Hemolytic, Autoimmune; Animals; Antineoplastic Agents, Phytogenic; Azathioprine; Dog Disease | 2008 |
Timing of myelosuppression during thiopurine therapy for inflammatory bowel disease: implications for monitoring recommendations.
Topics: Adult; Aged; Antimetabolites; Azathioprine; Bone Marrow; Cohort Studies; Drug Monitoring; Female; Hu | 2009 |
Successful treatment of amegakaryocytic thrombocytopenia with azathioprine.
Topics: Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Megakaryocytes; Thrombocytopenia | 2011 |
Survival analysis of patients with dermatomyositis and polymyositis: analysis of 192 Chinese cases.
Topics: Adult; Aged; Antirheumatic Agents; Azathioprine; Dermatomyositis; Diabetes Complications; Female; Fo | 2011 |
Dermatomyositis associated with generalized subcutaneous edema and Evans syndrome.
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Dermatomyositis; Edema; Female; Glucocorticoids; Humans | 2012 |
[Clinical and laboratory-diagnosed parameters in 21 dogs with primary immune-mediated thrombocytopenia].
Topics: Animals; Azathioprine; Dog Diseases; Dogs; Female; Glucocorticoids; Immunosuppressive Agents; Male; | 2011 |
Infliximab- and azathioprine-related severe neutropenia and thrombocytopenia in a case with Crohn's disease.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Crohn | 2011 |
The successful use of plasma exchange and immunosuppression in the management of acquired Glanzmann's thrombasthenia.
Topics: Anticoagulants; Azathioprine; Combined Modality Therapy; Female; Gastrointestinal Hemorrhage; Hepari | 2002 |
Sirolimus: new preparation. No tangible advance in renal transplantation.
Topics: Azathioprine; Clinical Trials as Topic; Cyclosporine; Drug Approval; Drug Therapy, Combination; Euro | 2002 |
Long-term effectiveness of danazol corticosteroids and cytotoxic drugs in the treatment of hematologic manifestations of systemic lupus erythematosus.
Topics: Adult; Anemia, Hemolytic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathio | 2003 |
A case of Evans' syndrome in a patient with ulcerative colitis.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Azathioprine; Colitis, Ulcerative; Humans; Male; Methylprednis | 2003 |
A case of idiopathic thrombocytopenia and autoimmune hemolytic anemia treated with thymic irradiation and by administration of imuran and actinomycin-C.
Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Azathioprine; Dactinomycin; H | 1963 |
Flow cytometric detection of platelet-bound antibody in three horses with immune-mediated thrombocytopenia.
Topics: Animals; Autoantibodies; Azathioprine; Blood Platelets; Female; Flow Cytometry; Glucocorticoids; Hor | 2004 |
Fatal cerebral involvement in systemic aspergillosis: a rare complication of steroid-treated autoimmune bicytopenia.
Topics: Adult; Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Autoimmune Diseases; | 2004 |
Late puerperal thrombohemorrhagic complications in a patient with antiphospholipid syndrome.
Topics: Abortion, Habitual; Activated Protein C Resistance; Adult; Anticoagulants; Antiphospholipid Syndrome | 2004 |
Thiopurine S-methyltransferase gene polymorphism in Japanese patients with autoimmune liver diseases.
Topics: Adult; Aged; Agranulocytosis; Asian People; Azathioprine; Bone Marrow; Female; Gastrointestinal Dise | 2007 |
Thiopurine metabolite monitoring in paediatric inflammatory bowel disease.
Topics: Adolescent; Azathioprine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Hype | 2007 |
Systemic lupus erythematosus with paraproteinemia.
Topics: Adult; Aged; Antibodies, Antinuclear; Azathioprine; Female; Glomerulonephritis; Glycoproteins; HLA A | 1984 |
[Immune thrombocytopenia in rectal cancer. Case report].
Topics: Aged; Azathioprine; Blood Platelets; Female; Glucocorticoids; Humans; Rectal Neoplasms; Thrombocytop | 1984 |
Neutropenia and thrombocytopenia in renal allograft recipients treated with trimethoprim-sulfamethoxazole.
Topics: Adult; Agranulocytosis; Azathioprine; Bone Marrow; Drug Combinations; Drug Synergism; Humans; Kidney | 1980 |
Platelet-bound IgG in systemic lupus erythematosus with and without thrombocytopenia.
Topics: Antigen-Antibody Complex; Azathioprine; Binding Sites, Antibody; Blood Platelets; Humans; Immunoglob | 1981 |
[Autoimmune thrombocytopenia in pregnant women: diagnosis, treatment and prevention of complications in children].
Topics: Adrenal Cortex Hormones; Adult; Autoimmune Diseases; Azathioprine; Female; Humans; Immunoglobulins, | 1994 |
Idiopathic portal hypertension in renal transplant recipients: report of two cases.
Topics: Adult; Angiography; Azathioprine; Catheterization; Celiac Artery; Endoscopy; Esophageal and Gastric | 1994 |
The mechanism of thrombocytopenia in patients with HIV infection.
Topics: Adolescent; Adult; Azathioprine; Blood Platelets; Cell Survival; Female; HIV Infections; Humans; Kin | 1994 |
Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Diseases; Female; Humans; Inflammatory Bow | 1993 |
Bone marrow function during quadruple immunosuppressive therapy after renal transplantation.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Female; Humans; Immunosuppression Therapy; | 1993 |
Scleroderma and autoimmune thrombocytopenia associated with ingestion of L-tryptophan.
Topics: Adult; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Azathioprine; Drug Therapy, Com | 1993 |
Azathioprine-induced bone marrow toxicity in four dogs.
Topics: Anemia, Hemolytic; Animals; Azathioprine; Bone Marrow; Bone Marrow Diseases; Dog Diseases; Dogs; Fem | 1996 |
Serial monitoring of clinical, haematological and immunological parameters in canine autoimmune haemolytic anaemia.
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Blood Transfusion; Bl | 1996 |
Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Azathioprine; Bone Marrow; Crohn Disease; DNA M | 2000 |
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Azathioprine; Child; Child, Preschool; Female; G | 2001 |
Thrombocytopenic episodes in patients with well-functioning renal allografts. Inverse relationship between platelet count and platelet size pointing to intermittent platelet destruction.
Topics: Autoantibodies; Azathioprine; Blood Cell Count; Blood Platelets; Cadaver; Cell Survival; Creatinine; | 1979 |
[Thrombocytopenia in hepatitis-B-antigenemia (author's transl)].
Topics: Azathioprine; Blood Cell Count; Blood Platelets; Female; Hepatitis; Hepatitis B Antigens; Humans; Li | 1976 |
Extensive intraglomerular fibrin deposition after renal transplantation: recovery without anticoagulation.
Topics: Acute Kidney Injury; Azathioprine; Biopsy, Needle; Cadaver; Cyclophosphamide; Fibrin; Graft Rejectio | 1975 |
[Idiopathic chronic thrombocytopenia treated with immunosuppressive agents].
Topics: Adult; Azathioprine; Chronic Disease; Drug Therapy, Combination; Female; Humans; Middle Aged; Predni | 1975 |
Idiopathic thrombocytopenic purpura in two children with Graves disease.
Topics: Azathioprine; Child; Female; Graves Disease; Humans; Prednisone; Propylthiouracil; Purpura; Purpura, | 1975 |
Antilymphocyte globulin with a small dose of cyclosporine A and prednisone as the induction of immunosuppression in renal allograft recipients.
Topics: Acute Disease; Acute Kidney Injury; Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Drug Th | 1992 |
Systemic toxicosis associated with azathioprine administration in domestic cats.
Topics: Animals; Azathioprine; Bone Marrow; Cat Diseases; Cats; Female; Leukocyte Count; Male; Neutropenia; | 1992 |
Azathioprine for treatment of immune-mediated thrombocytopenia in two horses.
Topics: Animals; Autoimmune Diseases; Azathioprine; Dexamethasone; Drug Therapy, Combination; Female; Horse | 1991 |
Severe immune thrombocytopenia induced by neuroleptics.
Topics: Adult; Azathioprine; Female; Haloperidol; Humans; Methotrimeprazine; Platelet Count; Psychotic Disor | 1991 |
Cell-mediated cyclic thrombocytopenia treated with azathioprine.
Topics: Azathioprine; Bone Marrow; Cell Count; Colony-Forming Units Assay; Hematopoietic Stem Cells; Humans; | 1991 |
Possible cyclosporine-associated thrombocytopenia.
Topics: Aged; Azathioprine; Cyclosporins; Humans; Male; Thrombocytopenia | 1990 |
Danazol for the treatment of refractory autoimmune thrombocytopenia in systemic lupus erythematosus.
Topics: Adult; Aged; Antigen-Antibody Complex; Autoimmune Diseases; Azathioprine; Blood Platelets; Combined | 1988 |
Results of treatment in immune thrombocytopenia.
Topics: Adolescent; Adult; Aged; Azathioprine; Cyclophosphamide; Female; Humans; Immune System Diseases; Mal | 1986 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Splenectomy does not cure the thrombocytopenia of systemic lupus erythematosus.
Topics: Adult; Aged; Autoimmune Diseases; Azathioprine; Female; Humans; Immunosuppressive Agents; Lupus Eryt | 1985 |
[Treatment of chronic hepatitis by immunodepressors].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Biopsy; Blood Protein Disorders; Fem | 1969 |
A controlled trial antilymphocyte globulin therapy (ALG) in man.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Dactinomycin; Goats; Graft Rejection; Heparin; Histocom | 1972 |
Treatment of immunologic diseases with cytostatics.
Topics: Anemia; Anemia, Hemolytic, Autoimmune; Asthma; Autoimmune Diseases; Azathioprine; Dyspepsia; gamma-G | 1969 |
Antilymphocyte-serum preparations in treatment of renal-allograft rejection.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cadaver; Female; gamma-Globulins; Histocompatibility; Hum | 1970 |
Immune response in patients with autoimmune thrombocytopenia and autoimmune haemolytic anaemia receiving azathioprine.
Topics: Anemia, Hemolytic, Autoimmune; Animals; Antibodies; Antibody Formation; Autoantibodies; Autoimmune D | 1974 |
[Immunosuppressive agents in hematology].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Agranulocytosis; Anemia, Hemolytic, Autoimmune | 1970 |
[Immunosuppressive agents in hematology].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Agranulocytosis; Anemia, He | 1970 |
Platelet survival and sequestration patterns in thrombocytopenic disorders.
Topics: Adult; Aged; Azathioprine; Blood Platelets; Cell Survival; Chloramphenicol; Chromium Isotopes; Dexam | 1972 |
Serum IgG and renal transplantation.
Topics: Adult; Azathioprine; Creatinine; Escherichia coli Infections; Female; Graft Rejection; Hematocrit; H | 1973 |
The spleen in chronic renal failure and renal transplantation.
Topics: Adolescent; Adult; Anemia; Azathioprine; Bone Marrow Cells; Child; Female; Hemosiderin; Humans; Kidn | 1972 |
[Therapy of autoimmune thrombocytopenia in childhood].
Topics: Agranulocytosis; Autoimmune Diseases; Azathioprine; Child; Cushing Syndrome; Humans; Prednisone; Spl | 1972 |
Apparent depression of antigens of the Kell blood group system associated with autoimmune acquired haemolytic anaemia.
Topics: Adolescent; Agranulocytosis; Anemia, Hemolytic, Autoimmune; Azathioprine; Blood Group Antigens; Bloo | 1972 |
[Immunosuppressive therapy in immuno-hematologic diseases].
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Humans; Immunosuppressive Agents; Mercaptopurine; Throm | 1972 |
The treatment of rheumatoid arthritis with azathioprine.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Male; Nausea | 1972 |
Mydriasis of unusual cause in a thrombocytopenic, anemic woman with temporary amaurosis.
Topics: Adult; Anemia; Azathioprine; Blindness; Blood Cell Count; Blood Platelets; Curettage; Dexamethasone; | 1973 |
Treatment of psoriasis with azathioprine.
Topics: Alcohol Drinking; Anemia; Azathioprine; Biopsy; Blood Cell Count; Chemical and Drug Induced Liver In | 1974 |
[Azathioprine in chronic thrombocytopenia].
Topics: Azathioprine; Chronic Disease; Humans; Hyperbilirubinemia; Remission, Spontaneous; Thrombocytopenia | 1974 |
Vincristine therapy of idiopathic and secondary thrombocytopenias.
Topics: Adult; Aged; Azathioprine; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Child; Cyclophos | 1974 |
Erythrocyte deformation and hemolytic anemia coincident with the microvascular disease of rejecting renal homotransplants.
Topics: Adult; Anemia, Hemolytic; Azathioprine; Erythrocytes; Female; Humans; Kidney Transplantation; Male; | 1968 |
[Immunosuppressive treatment for heterologous cardiac transplantation. Its possible efficacy in a rejection crisis].
Topics: Animals; Azathioprine; Betamethasone; Dexamethasone; Glucocorticoids; Graft Rejection; Heart Transpl | 1969 |
Circulating megakaryocytes in immune thrombocytopenias.
Topics: Adolescent; Adult; Aged; Azathioprine; Blood Cell Count; Blood Platelets; Chromium Isotopes; Female; | 1972 |
[Conclusive observations on clinical and nosographic problems of thrombopenic disorders].
Topics: Azathioprine; Female; Humans; Italy; Male; Platelet Adhesiveness; Prednisone; Thrombocytopenia | 1972 |
[Position of immunosuppressive agents in the therapy of idiopathic thrombocytopenia].
Topics: Adolescent; Adult; Aged; Azathioprine; Female; Humans; Male; Mercaptopurine; Middle Aged; Splenectom | 1972 |
[Recommendations for immunosuppressive therapy of autoimmune haemolytic anaemia and idiopathic thrombocytopenic purpura].
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Azathioprine; Child; Coombs Test; Diagnosis, | 1972 |
[Pancytopenia and bone-marrow changes in chronic active hepatitis].
Topics: Adult; Aged; Anemia, Aplastic; Azathioprine; Bone Marrow Examination; Chronic Disease; Female; Hepat | 1972 |
[Immunosuppressive therapy of thrombopenias].
Topics: Adult; Aged; Azathioprine; Blood Platelets; Female; Humans; Immunosuppressive Agents; Middle Aged; T | 1971 |
The treatment of cryptogenic fibrosing alveolitis with immunosuppressant drugs.
Topics: Adult; Agglutination Tests; Antibodies, Antinuclear; Azathioprine; Chlorambucil; Complement Fixation | 1971 |
[Results of immunosuppressive treatment of visceral lupus erythematosus].
Topics: Adolescent; Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agen | 1969 |
[Thrombocyte survival time in thrombocytopenias].
Topics: Azathioprine; Blood Platelets; Chromium Isotopes; Diagnosis, Differential; Female; Humans; Hypersple | 1970 |
[Treatment of chronic glomerulonephritis with imuran].
Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Blood Sedimentation; Child; Chronic Disease; Colic; D | 1970 |
[Long-term therapy of chronic hepatitis].
Topics: Adolescent; Adult; Aged; Antacids; Azathioprine; Child; Child, Preschool; Chronic Disease; Diet Ther | 1970 |
[Immunosuppressive treatment of chronic hepatitis].
Topics: Adolescent; Adult; Aged; Azathioprine; Blood Proteins; Chronic Disease; Depression, Chemical; Dexame | 1970 |
[Immunosuppressive therapy in autoimmune diseases].
Topics: Anemia, Hemolytic; Antineoplastic Agents; Autoimmune Diseases; Azathioprine; Collagen Diseases; Huma | 1971 |
Methotrexate and the platelet count.
Topics: Antineoplastic Agents; Azathioprine; Blood Cell Count; Blood Platelets; Fluorouracil; Humans; Leukop | 1968 |
[Azathioprine treatment of panmyelopathy with severe amegakaryocytic thrombocytopenia in children].
Topics: Anemia, Myelophthisic; Azathioprine; Child, Preschool; Female; Humans; Thrombocytopenia | 1968 |
A circulating anticoagulant directed against antihaemophilic globulin (factor 8) combined with thrombocytopenia. Report of a case successfully treated by an immunosuppressive agent.
Topics: Animals; Antibodies; Anticoagulants; Antigens; Azathioprine; Blood Coagulation Disorders; Blood Coag | 1968 |