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azathioprine and Thromboembolism

azathioprine has been researched along with Thromboembolism in 15 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.

Research Excerpts

ExcerptRelevanceReference
"Azathioprine was the probable causative agent of warfarin resistance according to the Naranjo probability scale, and a possible causative agent according to the Drug Interaction Probability Scale."1.35Azathioprine-induced warfarin resistance. ( Pendleton, RC; Rondina, MT; Vazquez, SR, 2008)
"Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare disorder characterized by a bleeding tendency due to factor II deficiency associated with the presence of lupus anticoagulant (LAC) autoantibodies."1.33Thromboembolism complicating the treatment of lupus anticoagulant hypoprothrombinemia syndrome. ( Rich, E; Senécal, JL; Vinet, E, 2006)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's4 (26.67)18.2507
2000's3 (20.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Vroey, B1
Colombel, JF1
Gregory, CR1
Kyles, AE1
Bernsteen, L1
Mehl, M1
Vinet, E1
Rich, E1
Senécal, JL1
Vazquez, SR1
Rondina, MT1
Pendleton, RC1
Kronenberg, F2
Königsrainer, A2
Lhotta, K2
Margreiter, R1
Dieplinger, H1
König, P2
Hestin, D1
Legrand, E1
Mertes, M1
Renoult, E1
Kessler, M1
Edwards, CM1
Morgan, JD1
Donnelly, PK1
Vanrenterghem, Y1
Roels, L1
Lerut, T1
Gruwez, J1
Michielsen, P1
Gresele, P1
Deckmyn, H1
Colucci, M1
Arnout, J1
Vermylen, J1
Gruber, SA3
Pescovitz, M1
Simmons, RL3
Najarian, JS3
Ascher, NL3
Payne, WD3
Sutherland, DE3
Elick, B1
Fryd, DS3
Vercellotti, G1
Dunn, DL1
Pescovitz, MD1
Kawana, S1
Katori, M1
Ohta, M1
Nishiyama, S1
Stummvoll, HK1
Pinggera, WF1
Oppolzer, R1
Singer, F1
Wolf, A1
Bennett, WM1
Boileau, M1
Barry, JM1
Lawson, RK1
Hodges, CV1

Reviews

1 review available for azathioprine and Thromboembolism

ArticleYear
IBD in 2010: optimizing treatment and minimizing adverse events.
    Nature reviews. Gastroenterology & hepatology, 2011, Volume: 8, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Gastrointestinal Agents; Hu

2011

Trials

5 trials available for azathioprine and Thromboembolism

ArticleYear
Cyclosporine-related hypercoagulability: fact or fiction?
    Transplantation proceedings, 1992, Volume: 24, Issue:6

    Topics: Adolescent; Adult; Aged; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Drug Administ

1992
Thromboembolic complications after renal transplantation: results from the randomized trial of cyclosporine v azathioprine-antilymphocyte globulin.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 2

    Topics: Antilymphocyte Serum; Azathioprine; Cardiovascular Diseases; Cyclosporins; Humans; Kidney Transplant

1987
Erythrocytosis and thromboembolic complications after renal transplantation: results from a randomized trial of cyclosporine versus azathioprine-antilymphocyte globulin.
    Transplantation proceedings, 1988, Volume: 20, Issue:3 Suppl 3

    Topics: Antilymphocyte Serum; Azathioprine; Cyclosporins; Humans; Kidney Transplantation; Polycythemia; Pros

1988
Thromboembolic complications in renal allograft recipients. A report from the prospective randomized study of cyclosporine versus azathioprine-antilymphocyte globulin.
    Transplantation, 1987, Volume: 44, Issue:6

    Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Cyclosporins; Diabe

1987
[Large intravenous doses of cortisone in renal transplantation].
    Wiener medizinische Wochenschrift (1946), 1974, Volume: 124, Issue:15

    Topics: Adolescent; Adult; Azathioprine; Child; Diabetes Mellitus; Gastrointestinal Hemorrhage; Graft vs Hos

1974

Other Studies

9 other studies available for azathioprine and Thromboembolism

ArticleYear
Results of clinical renal transplantation in 15 dogs using triple drug immunosuppressive therapy.
    Veterinary surgery : VS, 2006, Volume: 35, Issue:2

    Topics: Animals; Azathioprine; Cyclosporine; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Graft Re

2006
Thromboembolism complicating the treatment of lupus anticoagulant hypoprothrombinemia syndrome.
    The Journal of rheumatology, 2006, Volume: 33, Issue:10

    Topics: Adrenal Cortex Hormones; Antiphospholipid Syndrome; Azathioprine; Central Nervous System Diseases; C

2006
Azathioprine-induced warfarin resistance.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:7

    Topics: Adult; Anticoagulants; Azathioprine; Contraindications; Drug Interactions; Drug Resistance; Female;

2008
Conversion from cyclosporin to azathioprine after kidney transplantation.
    Lancet (London, England), 1995, Jun-10, Volume: 345, Issue:8963

    Topics: Apolipoproteins A; Azathioprine; Cardiovascular Diseases; Cyclosporine; Drug Therapy, Combination; H

1995
Renal artery thromboembolism and immunosuppressive therapy.
    Nephron, 1996, Volume: 72, Issue:1

    Topics: Azathioprine; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Tran

1996
[Polycythemia after kidney transplantation].
    Presse medicale (Paris, France : 1983), 1992, Dec-02, Volume: 21, Issue:41

    Topics: Adult; Azathioprine; Erythropoietin; Female; Humans; Kidney Transplantation; Male; Middle Aged; Poly

1992
Thromboembolic complications and haemostatic changes in cyclosporin-treated cadaveric kidney allograft recipients.
    Lancet (London, England), 1985, May-04, Volume: 1, Issue:8436

    Topics: Azathioprine; Blood Coagulation Factors; Blood Coagulation Tests; Cyclosporins; Hemostasis; Humans;

1985
Microcirculatory changes during skin allograft rejection and prolongation of survival time by antiplatelet agents.
    International journal of tissue reactions, 1986, Volume: 8, Issue:2

    Topics: Acrylates; Animals; Arterioles; Azathioprine; Blood Platelets; Capillaries; Graft Occlusion, Vascula

1986
Role of splenectomy in renal transplantation.
    Urology, 1973, Volume: 2, Issue:5

    Topics: Analysis of Variance; Antilymphocyte Serum; Azathioprine; Cadaver; Creatinine; Graft Rejection; Huma

1973