azathioprine has been researched along with T-Cell Lymphoma in 17 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the first 2 cases of hepatosplenic T-cell lymphoma in adolescents diagnosed with autoimmune hepatitis under long-term treatment with azathioprine." | 3.83 | Two Cases of Hepatosplenic T-Cell Lymphoma in Adolescents Treated for Autoimmune Hepatitis. ( Arrenberg, P; Brinkert, F; Grabhorn, E; Krech, T; Lohse, A; Schramm, C, 2016) |
| "All azathioprine treated mice showed signs of drug-associated toxicity such as weight loss and development of splenic T-cell lymphomas." | 3.80 | Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis. ( D'Haens, GR; Heijmans, J; Jansen, M; Levin, AD; Muncan, V; Rosekrans, SL; Schukking, M; van den Brink, GR; van Lidth de Jeude, JF; Wielenga, MC, 2014) |
| "A 47-year-old man with dermatomyositis and interstitial pneumonia had been treated with prednisolone since May, 1992, and with azathioprine since April, 1993." | 3.69 | [Primary pulmonary non-Hodgkin's lymphoma in a patient with dermatomyositis]. ( Arima, N; Kawamata, N; Kohyama, T; Mori, H; Tanaka, H; Terashi, K; Yamada, H; Yamaguchi, A, 1997) |
| "Pediatric ulcerative colitis tends to present with more severe and more extensive involvement than in adults." | 2.44 | IBD in children: lessons for adults. ( Haller, CA; Markowitz, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Rastogi, P | 1 |
| Nada, R | 1 |
| Akome, J | 1 |
| Kotobuki, Y | 1 |
| Maeda, T | 1 |
| Nojima, S | 1 |
| Shimada, N | 1 |
| Nakagawa, Y | 1 |
| Yamaoka, T | 1 |
| Kiyohara, E | 1 |
| Katayama, I | 1 |
| Wataya-Kaneda, M | 1 |
| Fujimoto, M | 1 |
| Mavilia, M | 1 |
| McAuliffe, A | 1 |
| Hafeez, S | 1 |
| Vaziri, H | 1 |
| Wielenga, MC | 1 |
| van Lidth de Jeude, JF | 1 |
| Rosekrans, SL | 1 |
| Levin, AD | 1 |
| Schukking, M | 1 |
| D'Haens, GR | 1 |
| Heijmans, J | 1 |
| Jansen, M | 1 |
| Muncan, V | 1 |
| van den Brink, GR | 1 |
| Begun, J | 1 |
| Brinkert, F | 1 |
| Arrenberg, P | 1 |
| Krech, T | 1 |
| Grabhorn, E | 1 |
| Lohse, A | 1 |
| Schramm, C | 1 |
| van de Meeberg, MM | 1 |
| Derikx, LA | 1 |
| Sinnige, HA | 1 |
| Nooijen, P | 1 |
| Schipper, DL | 1 |
| Nissen, LH | 1 |
| Moran, G | 1 |
| Dillon, J | 1 |
| Green, J | 1 |
| Ochenrider, MG | 1 |
| Patterson, DJ | 1 |
| Aboulafia, DM | 1 |
| Rashidi, A | 1 |
| Lee, ME | 1 |
| Fisher, SI | 1 |
| Deepak, P | 1 |
| Sifuentes, H | 1 |
| Sherid, M | 1 |
| Stobaugh, D | 1 |
| Sadozai, Y | 1 |
| Ehrenpreis, ED | 1 |
| Bašić Kinda, S | 1 |
| Duraković, N | 1 |
| Dotlić, S | 1 |
| Serventi Seiwerth, R | 1 |
| Davidović Mrsić, S | 1 |
| Dubravčić, K | 1 |
| Aurer, I | 1 |
| Medlicott, SA | 1 |
| Coderre, S | 1 |
| Horne, G | 1 |
| Panaccione, R | 1 |
| Haller, CA | 1 |
| Markowitz, J | 1 |
| Mori, H | 1 |
| Yamada, H | 1 |
| Terashi, K | 1 |
| Kohyama, T | 1 |
| Kawamata, N | 1 |
| Yamaguchi, A | 1 |
| Arima, N | 1 |
| Tanaka, H | 1 |
| Olesen, LL | 1 |
| Mølby, L | 1 |
| Kotlyar, DS | 1 |
| Blonski, W | 1 |
| Diamond, RH | 1 |
| Wasik, M | 1 |
| Lichtenstein, GR | 1 |
3 reviews available for azathioprine and T-Cell Lymphoma
| Article | Year |
|---|---|
Hepatosplenic T-cell lymphoma in a young man with Crohn's disease: case report and literature review.
Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Ag | 2010 |
IBD in children: lessons for adults.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; An | 2007 |
Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality.
Topics: Chromosome Disorders; Humans; Inflammatory Bowel Diseases; Lymphoma, T-Cell; Mercaptopurine; Splenic | 2010 |
14 other studies available for azathioprine and T-Cell Lymphoma
| Article | Year |
|---|---|
How Does It Look in an Autopsy? Hepatosplenic T-Cell Lymphoma in a Patient with Crohn’s Disease on Azathioprine
Topics: Adult; Antimetabolites, Antineoplastic; Azathioprine; Crohn Disease; Humans; Lymphoma, T-Cell; Male | 2020 |
Case of hepatosplenic T-cell lymphoma in a patient with dermatomyositis treated with prednisolone and azathioprine.
Topics: Azathioprine; Dermatomyositis; Humans; Lymphoma, T-Cell; Prednisolone | 2021 |
Hepatosplenic T cell lymphoma: a unifying entity in a patient with hemolytic anemia, massive splenomegaly, and liver dysfunction.
Topics: Adult; Anemia, Hemolytic; Azathioprine; Biopsy; Chronic Disease; Colitis, Ulcerative; Fatal Outcome; | 2018 |
Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Azathioprine; Female; Genes, APC; Lymp | 2014 |
Inflammatory bowel disease in the clinic: Escalation and de-escalation of therapy: A longitudinal case-based discussion.
Topics: Adolescent; Azathioprine; Crohn Disease; Drug Substitution; Drug Therapy, Combination; Enteral Nutri | 2016 |
Two Cases of Hepatosplenic T-Cell Lymphoma in Adolescents Treated for Autoimmune Hepatitis.
Topics: Adolescent; Azathioprine; Female; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver Neo | 2016 |
Hepatosplenic T-cell lymphoma in a 47-year-old Crohn's disease patient on thiopurine monotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Biopsy; Crohn Disease; Drug Administra | 2016 |
Crohn's disease, hepatosplenic T-cell lymphoma and no biological therapy: are we barking up the wrong tree?
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Glucocorticoids; Humans | 2009 |
Hepatosplenic αβ T-cell lymphoma associated with azathioprine therapy.
Topics: Azathioprine; Female; Humans; Immunosuppressive Agents; Liver Neoplasms; Lupus Erythematosus, System | 2012 |
T-cell non-Hodgkin's lymphomas reported to the FDA AERS with tumor necrosis factor-alpha (TNF-α) inhibitors: results of the REFURBISH study.
Topics: Adalimumab; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anti-Inflammato | 2013 |
Hepatosplenic αβ T-cell lymphoma arising after long-term azathioprine therapy successfully treated with allogeneic bone marrow transplant.
Topics: Azathioprine; Bone Marrow Transplantation; Crohn Disease; Humans; Immunosuppressive Agents; Liver Ne | 2013 |
Multimodal immunosuppressant therapy in steroid-refractory common variable immunodeficiency sprue: a case report complicating cytomegalovirus infection.
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Antiviral Agents; Azathioprine; Celiac Disease; Com | 2006 |
[Primary pulmonary non-Hodgkin's lymphoma in a patient with dermatomyositis].
Topics: Azathioprine; Dermatomyositis; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Lung N | 1997 |
[Malignant T-cell neoplasia during treatment with azathioprine and prednisone after kidney transplantation].
Topics: Azathioprine; Humans; Kidney Transplantation; Lymphoma, T-Cell; Male; Middle Aged; Prednisone; Time | 1991 |