Page last updated: 2024-10-23

azathioprine and Stunted Growth

azathioprine has been researched along with Stunted Growth in 19 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Guidelines for treatment of ulcerative colitis in children have been created by the working group of the Japanese Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Japanese Society for Pediatric Inflammatory Bowel Disease."2.43[Guidelines for treatment of ulcerative colitis in children]. ( Tomomasa, T, 2005)
"Diagnostic criteria for CD, ulcerative colitis (UC), and indeterminate colitis (IC) were defined."1.33Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease. ( Bonova, O; Dedek, P; Frühauf, P; Havlickova, A; Janatova, T; Jimramovsky, F; Klimova, L; Klusacek, D; Kocourkova, D; Kolek, A; Kotalova, R; Maly, J; Marx, D; Nevoral, J; Petro, R; Petru, O; Plasilova, I; Pozler, O; Schreierova, I; Seidl, Z; Sekyrova, I; Semendak, N; Stanek, J; Sulakova, A; Sykora, J; Toukalkova, L; Travnickova, R; Volf, V; Zahradnicek, L; Zenisková, I, 2006)
" CsA dosage remained unchanged in the range of 200 mg/m2/day; CsA whole blood trough level was 120 to 130 ng/mL throughout the years."1.28Long-term results of cyclosporin A therapy in children. ( Bökenkamp, A; Brodehl, J; Hoyer, PF; Offner, G, 1992)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's6 (31.58)18.2507
2000's3 (15.79)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Verkasalo, M1
Tomomasa, T1
Pozler, O1
Maly, J1
Bonova, O1
Dedek, P1
Frühauf, P1
Havlickova, A1
Janatova, T1
Jimramovsky, F1
Klimova, L1
Klusacek, D1
Kocourkova, D1
Kolek, A1
Kotalova, R1
Marx, D1
Nevoral, J1
Petro, R1
Petru, O1
Plasilova, I1
Seidl, Z1
Sekyrova, I1
Semendak, N1
Schreierova, I1
Stanek, J1
Sykora, J1
Sulakova, A1
Toukalkova, L1
Travnickova, R1
Volf, V1
Zahradnicek, L1
Zenisková, I1
Burren, CP1
Jones, CL1
Francis, DM1
Powell, HR1
Walker, RG1
Hokken-Koelega, AC1
Van Zaal, MA1
de Ridder, MA1
Wolff, ED1
De Jong, MC1
Donckerwolcke, RA1
De Muinck Keizer-Schrama, SM1
Drop, SL1
Markowitz, J1
Grancher, K1
Rosa, J1
Aiges, H1
Daum, F1
Sarna, S1
Sipilä, I1
Rönnholm, K1
Koistinen, R1
Holmberg, C1
Potter, DE1
Holliday, MA1
Wilson, CJ1
Salvatierra, O1
Belzer, FO1
Kasper, H1
Offner, G3
Brandis, M1
Brodehl, J3
Krohn, HP1
Pichlmayr, R1
Tidow, G1
Scott, JR1
Bökenkamp, A1
Hoyer, PF1
Aschendorff, C1
Schrago, R1
Miescher, PA1
Williams, GM1
Lee, HM1
Hume, DM1
Cicognani, A1
Mei, V1
Pirazzoli, P1
Tassoni, P1
Collina, A1
Tazzari, R1
Cacciari, E1
Saenger, P1
Wiedemann, E1
Schwartz, E1
Korth-Schutz, S1
Lewy, JE1
Riggio, RR1
Rubin, AL1
Stenzel, KH1
New, MI1
Bell, MJ1
Martin, LW1
Gonzales, LL1
McEnery, PT1
West, CD1
Rinawi, F1
Rosenbach, Y1
Assa, A1
Shamir, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nutritional Status and Body Composition in Children With Inflammatory Bowel Disease: A Prospective Cohort Study[NCT02704026]72 participants (Actual)Observational2015-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for azathioprine and Stunted Growth

ArticleYear
[Drug therapy and nutrition therapy of a young patient with Crohn disease].
    Duodecim; laaketieteellinen aikakauskirja, 2003, Volume: 119, Issue:7

    Topics: Adjuvants, Immunologic; Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal

2003
[Guidelines for treatment of ulcerative colitis in children].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63, Issue:5

    Topics: Azathioprine; Child; Colitis, Ulcerative; Contraindications; Cyclosporins; Growth Disorders; Humans;

2005

Trials

1 trial available for azathioprine and Stunted Growth

ArticleYear
Recombinant human growth hormone improves growth in children receiving glucocorticoid treatment after liver transplantation.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:4

    Topics: Azathioprine; Child; Cyclosporine; Drug Monitoring; Drug Therapy, Combination; Female; Follow-Up Stu

1996

Other Studies

16 other studies available for azathioprine and Stunted Growth

ArticleYear
Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 42, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Aminosalicylic Acids; Azathioprine; Child; Child,

2006
Renal transplantation in young children.
    Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:2

    Topics: Azathioprine; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies;

1995
Growth after renal transplantation in prepubertal children: impact of various treatment modalities.
    Pediatric research, 1994, Volume: 35, Issue:3

    Topics: Azathioprine; Body Height; Child; Child, Preschool; Cyclosporine; Drug Administration Schedule; Fema

1994
Growth failure in pediatric inflammatory bowel disease.
    Journal of pediatric gastroenterology and nutrition, 1993, Volume: 16, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Anthropometry; Azathioprine; Body Height; Child; Colitis, Ulcer

1993
Alternate-day steroids in children after renal transplantation.
    Transplantation proceedings, 1975, Volume: 7, Issue:1

    Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Child; Dactinomycin; Graft Rejection; Growth Disorde

1975
[Enteritis regionalis (Crohn's disease) (proceedings)].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1976, Issue:12

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Amyloidosis; Arthritis; Azathioprine; Child; Child

1976
[Kidney transplantation in children at Hannover from 1970 to 1977 (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1979, Mar-16, Volume: 104, Issue:11

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Female; Growth Disorders; Humans; Kidney Transpla

1979
Fetal growth retardation associated with maternal administration of immunosuppressive drugs.
    American journal of obstetrics and gynecology, 1977, Jul-15, Volume: 128, Issue:6

    Topics: Animals; Azathioprine; Body Weight; Cyclophosphamide; Depression, Chemical; Female; Fetal Diseases;

1977
Long-term results of cyclosporin A therapy in children.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:12 Suppl

    Topics: Adolescent; Antihypertensive Agents; Azathioprine; Child; Child, Preschool; Cyclosporine; Female; Fo

1992
Growth after renal transplantation: an update.
    Pediatric nephrology (Berlin, Germany), 1991, Volume: 5, Issue:4

    Topics: Adolescent; Azathioprine; Body Height; Bone Development; Child; Child, Preschool; Cyclosporine; Fema

1991
[The treatment of dermatomyositis].
    Schweizerische medizinische Wochenschrift, 1974, Sep-21, Volume: 104, Issue:38

    Topics: Adolescent; Adrenocorticotropic Hormone; Alpha-Globulins; Antibodies, Antinuclear; Antimetabolites;

1974
Renal transplants in children.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Azathioprine; Child; Epiphyses, Slipped; F

1969
[Body height increase and secretion of somatotropin in children with variously treated hephrotic syndromes].
    Minerva pediatrica, 1973, Apr-14, Volume: 25, Issue:13

    Topics: Adrenocorticotropic Hormone; Azathioprine; Body Height; Child; Child, Preschool; Chronic Disease; Fe

1973
Somatomedin and growth after renal transplantation.
    Pediatric research, 1974, Volume: 8, Issue:3

    Topics: Adolescent; Age Determination by Skeleton; Azathioprine; Body Height; Bone Development; Child; Gluco

1974
Alternate-day single-dose prednisone therapy: a method of reducing steroid toxicity.
    Journal of pediatric surgery, 1972, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Bacterial Infections; Bone Diseases; Cataract; Child; Child, Presch

1972
Ustekinumab for Resistant Pediatric Crohn Disease.
    Journal of pediatric gastroenterology and nutrition, 2016, Volume: 62, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Crohn Disease; Drug Administration Schedule; Drug Mo

2016