azathioprine has been researched along with Still's Disease, Adult-Onset in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Still's Disease, Adult-Onset: Systemic-onset rheumatoid arthritis in adults. It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalized lymphadenopathy and hepatosplenomegaly are more prominent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is characterized by high interindividual differences in bioavailability and metabolization." | 1.31 | Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine. ( Decaux, G; Desager, JP; Horsmans, Y; Prospert, F, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeh, HM | 1 |
| Liu, MF | 1 |
| Chang, KK | 1 |
| Liu, SM | 1 |
| Chen, CH | 1 |
| Nordström, D | 1 |
| Knight, A | 1 |
| Luukkainen, R | 1 |
| van Vollenhoven, R | 1 |
| Rantalaiho, V | 1 |
| Kajalainen, A | 1 |
| Brun, JG | 1 |
| Proven, A | 1 |
| Ljung, L | 1 |
| Kautiainen, H | 1 |
| Pettersson, T | 1 |
| Krzossok, S | 1 |
| Benck, U | 1 |
| van der Woude, FJ | 1 |
| Braun, C | 1 |
| Cefle, A | 1 |
| Cheema, GS | 1 |
| Quismorio, FP | 1 |
| Decaux, G | 1 |
| Prospert, F | 1 |
| Horsmans, Y | 1 |
| Desager, JP | 1 |
| Crétel, E | 1 |
| Richard, MA | 1 |
| Jean, R | 1 |
| Durand, JM | 1 |
| Hatz, HJ | 1 |
| Löffler, W | 1 |
| Mohr, M | 1 |
| Lindlbauer, R | 1 |
| Helmke, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open, Randomized Study Treating Refractory Adult-onset Still's Disease With Interleukin-1 Receptor Antagonist Anakinra (Kineret), Compared to an Established, Single Anti-rheumatic Drug Treatment[NCT01033656] | Phase 2 | 23 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Still's Disease, Adult-Onset
| Article | Year |
|---|---|
Pulmonary involvement in adult-onset Still's disease.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Chronic Disease; Cyclophosphamide; Humans; Immunoglobu | 1999 |
1 trial available for azathioprine and Still's Disease, Adult-Onset
| Article | Year |
|---|---|
Beneficial effect of interleukin 1 inhibition with anakinra in adult-onset Still's disease. An open, randomized, multicenter study.
Topics: Adult; Antirheumatic Agents; Azathioprine; Female; Humans; Interleukin 1 Receptor Antagonist Protein | 2012 |
6 other studies available for azathioprine and Still's Disease, Adult-Onset
| Article | Year |
|---|---|
Adult-onset Still's disease complicated with hemophagocytic syndrome.
Topics: Azathioprine; Bone Marrow; Drug Therapy, Combination; Female; Fever; Glucocorticoids; Humans; Immuno | 2010 |
[Disseminated intravascular coagulation, perimyocarditis and bilateral pleural empyema in adult Still's disease].
Topics: Adult; Azathioprine; Disseminated Intravascular Coagulation; Electrocardiography; Empyema, Pleural; | 2004 |
Leflunomide and azathioprine combination in refractory adult-onset Still's disease.
Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Still's Dis | 2005 |
Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine.
Topics: Adult; Azathioprine; Biological Availability; Churg-Strauss Syndrome; Erythrocyte Indices; Erythrocy | 2000 |
Still's-like disease, breast prosthesis, and collagen implants.
Topics: Azathioprine; Breast; Breast Implants; Collagen; Female; Ferritins; Glucocorticoids; Glycosylation; | 2001 |
[Therapy strategies for Still's syndrome of adults (AOSD)].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic | 1991 |