Page last updated: 2024-10-23

azathioprine and Stiff-Person Syndrome

azathioprine has been researched along with Stiff-Person Syndrome in 2 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Stiff-Person Syndrome: A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)

Research Excerpts

ExcerptRelevanceReference
"A 54-year-old woman with type 1 diabetes of about 2 years' duration developed painful cramps in the muscles of the abdominal wall, the back and the thighs."2.41[The stiff-man syndrome with diabetes mellitus type 1 and autoimmune thyroiditis]. ( Beischer, W; Gardill, K; Göppert, D; Wiethölter, H, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ajili, F1
McKeon, A1
Najeh, B1
Leila, M1
Imen, G1
Bassem, L1
Salah, O1
Göppert, D1
Gardill, K1
Beischer, W1
Wiethölter, H1

Reviews

1 review available for azathioprine and Stiff-Person Syndrome

ArticleYear
[The stiff-man syndrome with diabetes mellitus type 1 and autoimmune thyroiditis].
    Deutsche medizinische Wochenschrift (1946), 2000, Jul-07, Volume: 125, Issue:27

    Topics: Azathioprine; Chronic Disease; Diabetes Mellitus, Type 1; Diagnosis, Differential; Drug Therapy, Com

2000

Other Studies

1 other study available for azathioprine and Stiff-Person Syndrome

ArticleYear
[A low back pain revealing a stiff-man syndrome].
    The Pan African medical journal, 2013, Volume: 16

    Topics: Azathioprine; Diagnosis, Differential; Diazepam; Humans; Low Back Pain; Male; Middle Aged; Stiff-Per

2013