Page last updated: 2024-10-23

azathioprine and Stevens-Johnson Syndrome

azathioprine has been researched along with Stevens-Johnson Syndrome in 9 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burke, PA1
Malebranche, L1
Gakhal, M1
Rahman, E1
Saltzberg, M1
Dogra, S1
Saini, AG1
Suri, D1
Rawat, A1
Sodhi, KS1
Singh, S1
Vázquez-Sanabria, IL1
Mercado-Seda, R1
Varela-Rosario, N1
Vilá, LM1
Lateef, A1
Tan, KB1
Lau, TC1
Cisneros, CG1
Romiti, R1
Santi, CG1
Aoki, V1
Valente, NY1
Nico, MM1
Gervasini, A1
Krumlovsky, FA1
Del Greco, F1
Herdson, PB1
Lazar, P1
Schmidt, JG1
Lischka, G1
Bünger, P1
Delventhal, G1

Other Studies

9 other studies available for azathioprine and Stevens-Johnson Syndrome

ArticleYear
Sustained improvement of cardiac function with immunosuppressive therapy in a case of acute lymphocytic myocarditis secondary to allopurinol induced Stevens-Johnson syndrome.
    Delaware medical journal, 2012, Volume: 84, Issue:12

    Topics: Adrenal Cortex Hormones; Aged; Allopurinol; Antimetabolites; Azathioprine; Drug Therapy, Combination

2012
Bronchiolitis obliterans associated with Stevens-Johnson syndrome and response to azathioprine.
    Indian journal of pediatrics, 2014, Volume: 81, Issue:7

    Topics: Azathioprine; Bronchiolitis Obliterans; Child; Humans; Immunosuppressive Agents; Male; Remission Ind

2014
Efficacy of intravenous immunoglobulins in a patient with systemic lupus erythematosus presenting with Stevens-Johnson syndrome.
    BMJ case reports, 2015, Jul-22, Volume: 2015

    Topics: Adult; Azathioprine; Female; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Lupus E

2015
Acute generalized exanthematous pustulosis and toxic epidermal necrolysis induced by hydroxychloroquine.
    Clinical rheumatology, 2009, Volume: 28, Issue:12

    Topics: Aged; Antirheumatic Agents; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Drug Thera

2009
Toxic epidermal necrolysis-like cutaneous lupus erythematosus: A series of three patients.
    Acta dermato-venereologica, 2010, Volume: 90, Issue:2

    Topics: Adolescent; Azathioprine; Chloroquine; Diagnosis, Differential; Drug Therapy, Combination; Female; H

2010
[Case of Behcet's syndrome].
    Minerva medica, 1977, Feb-04, Volume: 68, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Arthritis, Reactive; Azathioprine; Behcet Syndrome; Cicatrix; Diagnosi

1977
Renal disease associated with toxic epidermal necrolysis (Lyell's disease).
    The American journal of medicine, 1974, Volume: 57, Issue:5

    Topics: Adult; Azathioprine; Biopsy; Blood Urea Nitrogen; Cholesterol; Creatinine; Female; Glomerulonephriti

1974
[Ophthalmological symptomatology, therapy and prognosis of Fuch's and Lyell's syndromes].
    Klinische Monatsblatter fur Augenheilkunde, 1970, Volume: 157, Issue:3

    Topics: Adult; Azathioprine; Body Weight; Corneal Opacity; Cortisone; Diagnosis, Differential; Entropion; Er

1970
[Azathioprine therapy in a severe case of "Lyell's syndrome"].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1968, Oct-15, Volume: 43, Issue:20

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Stevens-Johnson Syndrome

1968