Page last updated: 2024-10-23

azathioprine and Skin Ulcer

azathioprine has been researched along with Skin Ulcer in 18 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Skin Ulcer: An ULCER of the skin and underlying tissues.

Research Excerpts

ExcerptRelevanceReference
" Gradual reduction in prednisone dosage to 5 mg daily has coincided with a period of clinical resolution and modest improvement in lymphocyte reactivity."5.26Idiopathic pyoderma gangrenosum and impaired lymphocyte function: failure of azathioprine and corticosteroid therapy. ( Breathnach, SM; Valdimarsson, H; Wells, GC, 1981)
"In patients with systemic sclerosis or mixed connective tissue disease (MCTD) acral ulcers are considered as frequent manifestations that may lead to amputation and loss of function, respectively, as a result of secondary Raynaud's phenomenon."1.36[Treatment options of acral ulcers in MCTD]. ( Girndt, M; Herink, AK; Keysser, G; Köthe, L, 2010)
"A first case of Reiter's syndrome developing a severe systemic necrotising vasculitis is reported."1.30Systemic vasculitis associated with seronegative spondylarthropathy (Reiter's syndrome). ( Boehni, U; Christen, B; Greminger, P; Michel, BA, 1997)
" Gradual reduction in prednisone dosage to 5 mg daily has coincided with a period of clinical resolution and modest improvement in lymphocyte reactivity."1.26Idiopathic pyoderma gangrenosum and impaired lymphocyte function: failure of azathioprine and corticosteroid therapy. ( Breathnach, SM; Valdimarsson, H; Wells, GC, 1981)
"Treatment with azathioprine resulted in a progressive improvement in her condition."1.26A case of pulmonary veno-occlusive disease respondong to treatment with azathioprine. ( Hendry, AT; Sanderson, JE; Spiro, SG; Turner-Warwick, M, 1977)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199011 (61.11)18.7374
1990's1 (5.56)18.2507
2000's1 (5.56)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Ritter, CG1
de David Cruz, C1
Zamboni, S1
Busato, VB1
da Silveira, RG1
Provenzi, VO1
Bredemeier, M1
Chua, EP1
Mallett, RB1
Dahiya, S1
Matnani, R1
Peker, D1
Herink, AK1
Köthe, L1
Girndt, M1
Keysser, G1
McGinness, JL1
Spicknall, KE1
Mutasim, DF1
Tsanadis, GD1
Chouliara, ST1
Voulgari, PV1
Makrydimas, GV1
Drosos, AA1
Curtis, JJ1
Diethelm, AG1
Herrera, GA1
Crowell, WT1
Whelchel, JD1
Breathnach, SM1
Wells, GC1
Valdimarsson, H1
Boehni, U1
Christen, B1
Greminger, P1
Michel, BA1
Sanderson, JE1
Spiro, SG1
Hendry, AT1
Turner-Warwick, M1
Haim, S1
Friedman-Birnbaum, R1
Wallis, SM1
Walker-Smith, J1
Brachtel, R1
Lemmel, EM1
Mackay, IR1
Wall, AJ1
Menninger, H1
Sultan, N1
Müller, R1
Javett, SL1
Kavin, H1
Bremner, CG1
Schneider, J1
Levine, E1
Hinder, RA1
Salomon, MI1
Mandel, EH1
Gallo, G1
Schöpf, E1
Schulz, HJ1
Schulz, KH1

Other Studies

18 other studies available for azathioprine and Skin Ulcer

ArticleYear
EBV-positive mucocutaneous ulcer in a patient with systemic lupus erythematosus.
    Rheumatology (Oxford, England), 2020, 04-01, Volume: 59, Issue:4

    Topics: Azathioprine; Conservative Treatment; Deprescriptions; Epstein-Barr Virus Infections; Facial Dermato

2020
Cogan's syndrome with pyoderma gangrenosum: management of two uncommon disorders with aggressive presentation in a patient.
    BMJ case reports, 2018, Jun-19, Volume: 2018

    Topics: Administration, Intravenous; Azathioprine; Biopsy; Cogan Syndrome; Cyclophosphamide; Cyclosporine; D

2018
Azathioprine induced Epstein Barr virus-positive mucocutaneous ulcer arising in perianal fistula and abscess associated with Crohn's disease.
    Journal of Crohn's & colitis, 2014, Volume: 8, Issue:12

    Topics: Abscess; Anus Diseases; Azathioprine; Crohn Disease; Herpesvirus 4, Human; Humans; Immunosuppressive

2014
[Treatment options of acral ulcers in MCTD].
    Medizinische Klinik (Munich, Germany : 1983), 2010, Volume: 105, Issue:11

    Topics: Adult; Amides; Analgesia, Patient-Controlled; Angiography, Digital Subtraction; Autonomic Nerve Bloc

2010
Azathioprine-induced EBV-positive mucocutaneous ulcer.
    Journal of cutaneous pathology, 2012, Volume: 39, Issue:3

    Topics: Aged; Antigens, CD20; Antimetabolites, Antineoplastic; Azathioprine; B-Lymphocytes; Epstein-Barr Vir

2012
Outcome of pregnancy in a patient with relapsing polychondritis and pyoderma gangrenosum.
    Clinical rheumatology, 2002, Volume: 21, Issue:6

    Topics: Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Methylprednisolone; Necrosis; Polycho

2002
Recurrence of Wegener's granulomatosis in a cadaver renal allograft.
    Transplantation, 1983, Volume: 36, Issue:4

    Topics: Azathioprine; Cyclophosphamide; Glomerulonephritis; Granulomatosis with Polyangiitis; Humans; Kidney

1983
Idiopathic pyoderma gangrenosum and impaired lymphocyte function: failure of azathioprine and corticosteroid therapy.
    The British journal of dermatology, 1981, Volume: 104, Issue:5

    Topics: Azathioprine; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunity, Cellular; Lymphocyte A

1981
Systemic vasculitis associated with seronegative spondylarthropathy (Reiter's syndrome).
    Clinical rheumatology, 1997, Volume: 16, Issue:6

    Topics: Adult; Arthritis, Reactive; Azathioprine; Cyclophosphamide; Humans; Immunosuppressive Agents; Radiog

1997
A case of pulmonary veno-occlusive disease respondong to treatment with azathioprine.
    Thorax, 1977, Volume: 32, Issue:2

    Topics: Alopecia; Arthritis; Azathioprine; Female; Humans; Middle Aged; Pulmonary Veins; Raynaud Disease; Sk

1977
Pyoderma gangrenosum in immunosuppressed patients.
    Dermatologica, 1976, Volume: 153, Issue:1

    Topics: Adult; Azathioprine; Humans; Immunosuppression Therapy; Male; Methotrexate; Middle Aged; Penis; Pred

1976
An unusual case of Crohn's disease in a West Indian child.
    Acta paediatrica Scandinavica, 1976, Volume: 65, Issue:6

    Topics: Adolescent; Azathioprine; Child; Crohn Disease; Female; Humans; Hypertrophy; Perineum; Prednisolone;

1976
[Chronic vegetating pyodermia in cellular immune deficiency].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1976, Volume: 27, Issue:10

    Topics: Aged; Azathioprine; Blood Transfusion; Chronic Disease; Humans; Immunologic Deficiency Syndromes; Ma

1976
Azathioprine terapy of ulcerative colitis.
    The American journal of digestive diseases, 1968, Volume: 13, Issue:9

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Azathioprine; Colitis, Ulcerative; Female; Humans; M

1968
[Clinical aspects of Wegener's granulomatosis].
    Munchener medizinische Wochenschrift (1950), 1972, Sep-29, Volume: 114, Issue:39

    Topics: Azathioprine; Female; Granulomatosis with Polyangiitis; Humans; Mercaptopurine; Middle Aged; Oral Ma

1972
Some aspects of Crohn's disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Aug-11, Volume: 47, Issue:31

    Topics: Adult; Aged; Anus Diseases; Azathioprine; Colitis; Colitis, Ulcerative; Colonic Diseases; Crohn Dise

1973
Degos' disease associated with a "spontaneous cure" of diabetes.
    Journal of the American Geriatrics Society, 1971, Volume: 19, Issue:11

    Topics: Azathioprine; Diabetes Complications; Diabetes Mellitus; Female; Gastrointestinal Diseases; Glucocor

1971
[Azathioprine treatment of ulcerative dermatitis (pyoderma gangrenosum)].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1969, Volume: 20, Issue:12

    Topics: Aged; Azathioprine; Female; Humans; Pyoderma; Skin Ulcer

1969