Page last updated: 2024-10-23

azathioprine and Sinusitis

azathioprine has been researched along with Sinusitis in 8 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Sinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.

Research Excerpts

ExcerptRelevanceReference
" This study was undertaken to determine whether the addition of azathioprine (AZA) to glucocorticoids could achieve a higher sustained remission rate of newly diagnosed nonsevere eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA), microscopic polyangiitis (MPA), or polyarteritis nodosa (PAN)."9.24Adding Azathioprine to Remission-Induction Glucocorticoids for Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Microscopic Polyangiitis, or Polyarteritis Nodosa Without Poor Prognosis Factors: A Randomized, Controlled Trial. ( Agard, C; Baron, G; Bienvenu, B; Bourgarit, A; Cohen, P; Crestani, B; Delbrel, X; Diot, E; Geffray, L; Godmer, P; Groh, M; Guillevin, L; Le Guern, V; Le Jeunne, C; Lifermann, F; Limal, N; Liozon, E; Mékinian, A; Mouthon, L; Néel, A; Pagnoux, C; Papo, T; Puéchal, X; Quémeneur, T; Ravaud, P; Ruivard, M; Ruppert, AM; Sailler, L; Saraux, JL; Terrier, B, 2017)
" This study was undertaken to determine whether the addition of azathioprine (AZA) to glucocorticoids could achieve a higher sustained remission rate of newly diagnosed nonsevere eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA), microscopic polyangiitis (MPA), or polyarteritis nodosa (PAN)."5.24Adding Azathioprine to Remission-Induction Glucocorticoids for Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Microscopic Polyangiitis, or Polyarteritis Nodosa Without Poor Prognosis Factors: A Randomized, Controlled Trial. ( Agard, C; Baron, G; Bienvenu, B; Bourgarit, A; Cohen, P; Crestani, B; Delbrel, X; Diot, E; Geffray, L; Godmer, P; Groh, M; Guillevin, L; Le Guern, V; Le Jeunne, C; Lifermann, F; Limal, N; Liozon, E; Mékinian, A; Mouthon, L; Néel, A; Pagnoux, C; Papo, T; Puéchal, X; Quémeneur, T; Ravaud, P; Ruivard, M; Ruppert, AM; Sailler, L; Saraux, JL; Terrier, B, 2017)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Puéchal, X2
Pagnoux, C2
Baron, G2
Quémeneur, T2
Néel, A2
Agard, C2
Lifermann, F2
Liozon, E1
Ruivard, M2
Godmer, P1
Limal, N2
Mékinian, A1
Papo, T1
Ruppert, AM1
Bourgarit, A1
Bienvenu, B1
Geffray, L2
Saraux, JL2
Diot, E1
Crestani, B1
Delbrel, X1
Sailler, L1
Cohen, P2
Le Guern, V1
Terrier, B2
Groh, M1
Le Jeunne, C2
Mouthon, L2
Ravaud, P2
Guillevin, L2
Milczarek-Banach, J1
Brodzińska, K1
Jankowska, A1
Ambroziak, U1
Szczepankiewicz, B1
Nałęcz-Janik, J1
Miśkiewicz, P1
Wislez, M1
Cottin, V1
Aouba, A1
Bonnotte, B1
Joswig, H1
Flueckiger, C1
Infanger, A1
Tettenborn, B1
Felbecker, A1
Tsuji, RK1
Bittencourt, AG1
Arai, MH1
Santiago Gebrim, EM1
McMahon, NS1
Cooper, M1
Iorember, F1
English, R1
Lehmann, H1
Struve, C1
Fauci, AS1
Wolff, SM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of a New Treatment Strategy for Patients With Microscopic Polyangiitis, Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) Without Poor Prognosis Factors[NCT00647166]Phase 3114 participants (Actual)Interventional2008-05-31Completed
Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901]Phase 260 participants Interventional1999-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for azathioprine and Sinusitis

ArticleYear
Adding Azathioprine to Remission-Induction Glucocorticoids for Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Microscopic Polyangiitis, or Polyarteritis Nodosa Without Poor Prognosis Factors: A Randomized, Controlled Trial.
    Arthritis & rheumatology (Hoboken, N.J.), 2017, Volume: 69, Issue:11

    Topics: Adult; Aged; Asthma; Azathioprine; Churg-Strauss Syndrome; Disease Progression; Double-Blind Method;

2017

Other Studies

7 other studies available for azathioprine and Sinusitis

ArticleYear
[IgG4-related disease - a case report].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2017, Sep-29, Volume: 43, Issue:255

    Topics: Adult; Autoimmune Diseases; Azathioprine; Drug Therapy, Combination; Female; Hashimoto Disease; Hepa

2017
Non-severe eosinophilic granulomatosis with polyangiitis: long-term outcomes after remission-induction trial.
    Rheumatology (Oxford, England), 2019, 12-01, Volume: 58, Issue:12

    Topics: Adult; Aged; Asthma; Azathioprine; Churg-Strauss Syndrome; Disease Progression; Disease-Free Surviva

2019
Recurring meningoencephalitis in sinusitis-associated acute posterior multifocal placoid pigment epitheliopathy under prednisone tapering.
    BMJ case reports, 2011, May-10, Volume: 2011

    Topics: Anti-Inflammatory Agents; Azathioprine; Diagnosis, Differential; Fundus Oculi; Humans; Immunosuppres

2011
Cochleovestibular nerve involvement in multifocal fibrosclerosis.
    The Journal of laryngology and otology, 2012, Volume: 126, Issue:9

    Topics: Azathioprine; Biopsy; Diagnosis, Differential; Disease Progression; Female; Glucocorticoids; Humans;

2012
Just chronic sinusitis?
    Clinical pediatrics, 2012, Volume: 51, Issue:11

    Topics: Adolescent; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Biomarkers; Biopsy; Chronic Diseas

2012
[Liver changes in Wegener's granulomatosis (author's transl)].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1981, Volume: 134, Issue:5

    Topics: Azathioprine; Female; Glucocorticoids; Granulomatosis with Polyangiitis; Humans; Liver; Lung; Middle

1981
Wegener's granulomatosis: studies in eighteen patients and a review of the literature.
    Medicine, 1973, Volume: 52, Issue:6

    Topics: Adult; Aged; Azathioprine; Biopsy; Corneal Ulcer; Cyclophosphamide; Diagnosis, Differential; Ear Dis

1973