Page last updated: 2024-10-23

azathioprine and Shingles

azathioprine has been researched along with Shingles in 25 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Our experience with azathioprine in the treatment of rheumatoid arthritis covers ten years, during which 91 rheumatoid patients (66 female and 25 male) received this drug, with a median treatment period of 36 months."7.66Side-effects of azathioprine treatment in rheumatoid arthritis: analysis of 10 years of experience. ( Boerbooms, AM; Kruijsen, MW; Speerstra, F; van Beusekom, HJ; van de Putte, LB; Vandenbroucke, JP, 1982)
"We have described a 60-year-old woman with polymyalgia rheumatica treated initially with prednisone but ultimately with azathioprine and cyclophosphamide."3.67Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation. ( Canter, HG; Manz, HJ; Melton, J, 1986)
"Our experience with azathioprine in the treatment of rheumatoid arthritis covers ten years, during which 91 rheumatoid patients (66 female and 25 male) received this drug, with a median treatment period of 36 months."3.66Side-effects of azathioprine treatment in rheumatoid arthritis: analysis of 10 years of experience. ( Boerbooms, AM; Kruijsen, MW; Speerstra, F; van Beusekom, HJ; van de Putte, LB; Vandenbroucke, JP, 1982)
" Prednisolone dosage was gradually tapered to 10 mg/d at 6 months, when cyclophosphamide was replaced by azathioprine (2 mg/kg/d p."2.69Treatment of membranous lupus nephritis with nephrotic syndrome by sequential immunosuppression. ( Chan, KW; Chan, TM; Hao, WK; Lai, KN; Li, FK; Lui, SL; Tang, S, 1999)
" Cases (1555 patients with SLE who developed HZ) and controls (3049 age- and sex-matched patients with SLE but without HZ) were analyzed for use of various immunosuppressive medications in the preceding 3-month period, and dose-response relationships were determined."1.43Immunosuppressive medication use and risk of herpes zoster (HZ) in patients with systemic lupus erythematosus (SLE): A nationwide case-control study. ( Chen, GS; Hu, SC; Lin, CL; Lin, YC; Wang, TN; Yen, FL, 2016)
"Two patients presented cutaneous varicella complicated by pneumonia and esophagitis respectively, one patient had cutaneous herpes zoster and the other had fatal pneumonia possibly caused by the Herpesvirus."1.32[Opportunistic infections in patients with inflammatory bowel disease undergoing immunosuppressive therapy]. ( Bernal, I; Cabré, E; Domènech, E; García-Planella, E; Gassull, MA, 2003)
"We present the case of a patient with Crohn's disease under immunosuppressive therapy who developed a spontaneous covered spleen rupture in the course of a septic shock with DIG due to a Varizella zoster infection."1.32[Functional asplenia after severe varicella zoster-infection diagnosis by colour Doppler ultrasound]. ( Arnold, R; Diedrich, J; Eissele, R; Görg, C, 2003)
"Herpes zoster was observed in 76 of the 704 patients included in the study."1.30Varicella and zoster in children after kidney transplantation: long-term results of vaccination. ( Broyer, M; Gagnadoux, MF; Guest, G; Rouzioux, C; Tete, MJ, 1997)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199010 (40.00)18.7374
1990's3 (12.00)18.2507
2000's5 (20.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Jiang, N1
Jin, S1
Yu, C1
Zhao, J1
Wang, Q1
Tian, X1
Li, M1
Zeng, X1
Zisman, D1
Bitterman, H1
Shalom, G1
Feldhamer, I1
Comanesther, D1
Batat, E1
Greenberg-Dotan, S1
Cohen, S1
Cohen, AD1
Nimmrich, S1
Horneff, G1
Hu, SC1
Yen, FL1
Wang, TN1
Lin, YC1
Lin, CL1
Chen, GS1
Elliott, TR1
Miller, C1
Macrae, FA1
Hartley, A1
Pyne, D1
Bickerstaff, M1
Sifuentes Giraldo, WA1
de la Puente Bujidos, C1
de Blas Beorlegui, G1
López San Román, A1
Peña Arrebola, A1
Bernal, I1
Domènech, E1
García-Planella, E1
Cabré, E1
Gassull, MA1
Diedrich, J1
Görg, C1
Eissele, R1
Arnold, R1
Lemyze, M1
Tavernier, JY1
Chevalon, B1
Lamblin, C1
Manrique, J1
Rossich, E1
Hernández Sierra, A1
Speerstra, F1
Boerbooms, AM1
van de Putte, LB1
van Beusekom, HJ1
Kruijsen, MW1
Vandenbroucke, JP1
Plumb, R1
Doolittle, GC1
Broyer, M1
Tete, MJ1
Guest, G1
Gagnadoux, MF1
Rouzioux, C1
Chan, TM1
Li, FK1
Hao, WK1
Chan, KW1
Lui, SL1
Tang, S1
Lai, KN1
Vergara, M1
Brullet, E1
Campo, R1
Calvet, X1
Blanch, L1
Canavese, JC1
Spencer, ES2
Andersen, HK2
Manz, HJ1
Canter, HG1
Melton, J1
Lopez, C1
Simmons, RL1
Park, BH1
Najarian, JS1
Good, RA1
Forbes, MJ1
Sinclair, L1
Hersh, EM1
Freireich, EJ1
Currey, HL1
Rifkind, D1

Reviews

3 reviews available for azathioprine and Shingles

ArticleYear
Efficacy and safety of immunosuppressive agents for adults with lupus nephritis: a systematic review and network meta-analysis.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Adult; Azathioprine; Bone Marrow Diseases; Cyclophosphamide; Glucocorticoids; Herpes Zoster; Humans;

2023
[Lupus erythematosus, modern aspects (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1977, May-10, Volume: 66, Issue:19

    Topics: Antacids; Antibodies, Antinuclear; Antigen-Antibody Complex; Azathioprine; Chlorambucil; Cyclophosph

1977
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
    Transactions of the St. John's Hospital Dermatological Society, 1970, Volume: 56, Issue:2

    Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine;

1970

Trials

2 trials available for azathioprine and Shingles

ArticleYear
Treatment of membranous lupus nephritis with nephrotic syndrome by sequential immunosuppression.
    Lupus, 1999, Volume: 8, Issue:7

    Topics: Adult; Alopecia; Anti-Inflammatory Agents; Azathioprine; Cohort Studies; Cyclophosphamide; Drug Ther

1999
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
    Transactions of the St. John's Hospital Dermatological Society, 1970, Volume: 56, Issue:2

    Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine;

1970

Other Studies

21 other studies available for azathioprine and Shingles

ArticleYear
Psoriatic arthritis treatment and the risk of herpes zoster.
    Annals of the rheumatic diseases, 2016, Volume: 75, Issue:1

    Topics: Adalimumab; Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Azathioprine; Cyclosporine; Dru

2016
Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.
    Rheumatology international, 2015, Volume: 35, Issue:3

    Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Ag

2015
Immunosuppressive medication use and risk of herpes zoster (HZ) in patients with systemic lupus erythematosus (SLE): A nationwide case-control study.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Adrenal Cortex Hormones; Adult; Azathioprine; Cas

2016
Severe perianal shingles during azathioprine and budesonide treatment for Crohn's disease-preventable with zoster vaccine?
    BMJ case reports, 2016, Jul-20, Volume: 2016

    Topics: Adult; Animals; Azathioprine; Budesonide; Crohn Disease; Glucocorticoids; Herpes Zoster; Herpes Zost

2016
A near miss.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:3

    Topics: Abdominal Pain; Acyclovir; Adult; Antiviral Agents; Azathioprine; Connective Tissue Diseases; Female

2011
Herpes zoster motor neuropathy in a patient with previous motor paresis secondary to Vogt-Koyanagi-Harada disease.
    American journal of physical medicine & rehabilitation, 2013, Volume: 92, Issue:4

    Topics: Adult; Azathioprine; Colitis, Ulcerative; Disease Progression; Electromyography; Female; Herpes Zost

2013
[Opportunistic infections in patients with inflammatory bowel disease undergoing immunosuppressive therapy].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Acyclovir; Adult; Aged; Antiviral Agents; Azathioprine; Chickenpox; Crohn Disease; Disease Susceptib

2003
[Functional asplenia after severe varicella zoster-infection diagnosis by colour Doppler ultrasound].
    Zeitschrift fur Gastroenterologie, 2003, Volume: 41, Issue:4

    Topics: Adult; Atrophy; Azathioprine; Crohn Disease; Drug Therapy, Combination; Follow-Up Studies; Herpes Zo

2003
[Severe varicella zoster pneumonia during the course of treatment with azathioprine for Crohn's disease].
    Revue des maladies respiratoires, 2003, Volume: 20, Issue:5 Pt 1

    Topics: Adolescent; Azathioprine; Crohn Disease; Female; Herpes Zoster; Herpesvirus 3, Human; Humans; Immuno

2003
[Multiple complications after renal transplantation].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3

    Topics: Adult; Azathioprine; Cataract; Cholecystitis; Choledocholithiasis; Cyclosporine; Femur Head Necrosis

2004
Side-effects of azathioprine treatment in rheumatoid arthritis: analysis of 10 years of experience.
    Annals of the rheumatic diseases, 1982, Volume: 41 Suppl 1

    Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Bacterial Infections; Bone Marrow; Cardiovascular Disease

1982
Paraneoplastic pemphigus in a patient with non-Hodgkin's lymphoma.
    American journal of hematology, 1996, Volume: 52, Issue:1

    Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined Modality Thera

1996
Varicella and zoster in children after kidney transplantation: long-term results of vaccination.
    Pediatrics, 1997, Volume: 99, Issue:1

    Topics: Adrenal Cortex Hormones; Azathioprine; Chickenpox; Chickenpox Vaccine; Child; Child, Preschool; Enzy

1997
[Fulminant infection caused by varicella herpes zoster in patient with Crohn disease undergoing treatment with azathioprine].
    Gastroenterologia y hepatologia, 2001, Volume: 24, Issue:1

    Topics: Adult; Azathioprine; Crohn Disease; Fatal Outcome; Female; Herpes Zoster; Humans; Immunosuppressive

2001
Viral infections in renal allograft recipients treated with long-term immunosuppression.
    British medical journal, 1979, Oct-06, Volume: 2, Issue:6194

    Topics: Adult; Azathioprine; Cytomegalovirus Infections; Female; Follow-Up Studies; Herpes Zoster; Humans; K

1979
Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation.
    Southern medical journal, 1986, Volume: 79, Issue:8

    Topics: Azathioprine; Cranial Nerve Diseases; Cyclophosphamide; Drug Therapy, Combination; Female; Herpes Zo

1986
Clinically evident, non-terminal infections with herpesviruses and the wart virus in immunosuppressed renal allograft recipients.
    British medical journal, 1970, Aug-01, Volume: 3, Issue:5717

    Topics: Adolescent; Adult; Azathioprine; Child; Complement Fixation Tests; Cytomegalovirus Infections; Femal

1970
Cell-mediated and humoral immune responses or renal transplant recipients with cytomegalovirus infections.
    Clinical and experimental immunology, 1974, Volume: 16, Issue:4

    Topics: Antibody Formation; Azathioprine; Complement Fixation Tests; Cytomegalovirus Infections; Herpes Simp

1974
Lupus nephritis: response to azathioprine.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:8

    Topics: Adolescent; Azathioprine; Edema; Female; Glomerular Filtration Rate; Glomerulonephritis; Hematuria;

1974
Editorial: Focus on cutaneous host-defense failure in transplant recipients.
    JAMA, 1974, Jul-22, Volume: 229, Issue:4

    Topics: Azathioprine; Graft Rejection; Herpes Simplex; Herpes Zoster; Humans; Immunity, Cellular; Immunosupp

1974
The activation of varicella-zoster virus infections by immunosuppressive therapy.
    The Journal of laboratory and clinical medicine, 1966, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Chromatography, Gel; Complement Fixation Tests; Female

1966