azathioprine has been researched along with Rheumatoid Nodule in 5 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Rheumatoid Nodule: Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To obtain information on the occurrence of accelerated nodulosis during methotrexate (MTX) for rheumatoid arthritis (RA), localization, size and presence in heart and lungs of these nodules, predisposing factors, relationship with other extraarticular manifestations (EAM) and their histological features." | 9.07 | Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. An analysis of ten cases. ( Assmann, KJ; Boerbooms, AM; Fast, JH; Jeurissen, ME; Kerstens, PJ; van de Putte, LB, 1992) |
| "To obtain information on the occurrence of accelerated nodulosis during methotrexate (MTX) for rheumatoid arthritis (RA), localization, size and presence in heart and lungs of these nodules, predisposing factors, relationship with other extraarticular manifestations (EAM) and their histological features." | 5.07 | Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. An analysis of ten cases. ( Assmann, KJ; Boerbooms, AM; Fast, JH; Jeurissen, ME; Kerstens, PJ; van de Putte, LB, 1992) |
| "The etiology of rheumatoid nodules is still unknown." | 1.34 | Etanercept-related extensive pulmonary nodulosis in a patient with rheumatoid arthritis. ( Creemers, MC; den Broeder, A; van Ede, A; van Riel, P; Wagenaar, M, 2007) |
| "Retroperitoneal fibrosis is a disorder in which the retroperitoneal fat is the site of a subacute and chronic inflammatory reaction and is subsequently replaced by dense fibrotic tissue." | 1.30 | [Retroperitoneal fibrosis and arthritis--a manifestation of the same illness]. ( Stierle, HE; Störkel, S; Thiele, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Ede, A | 1 |
| den Broeder, A | 1 |
| Wagenaar, M | 1 |
| van Riel, P | 1 |
| Creemers, MC | 1 |
| Thiele, A | 1 |
| Störkel, S | 1 |
| Stierle, HE | 1 |
| Kerstens, PJ | 1 |
| Boerbooms, AM | 1 |
| Jeurissen, ME | 1 |
| Fast, JH | 1 |
| Assmann, KJ | 1 |
| van de Putte, LB | 1 |
| Langevitz, P | 1 |
| Maguire, L | 1 |
| Urowitz, M | 1 |
| Jayson, MI | 1 |
| Jones, DE | 1 |
2 trials available for azathioprine and Rheumatoid Nodule
| Article | Year |
|---|---|
Accelerated nodulosis during low dose methotrexate therapy for rheumatoid arthritis. An analysis of ten cases.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Dose-Response Relationship, Drug; Doub | 1992 |
Accelerated nodulosis during azathioprine therapy.
Topics: Arthritis, Rheumatoid; Azathioprine; Double-Blind Method; Female; Humans; Middle Aged; Rheumatoid No | 1991 |
3 other studies available for azathioprine and Rheumatoid Nodule
| Article | Year |
|---|---|
Etanercept-related extensive pulmonary nodulosis in a patient with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, C | 2007 |
[Retroperitoneal fibrosis and arthritis--a manifestation of the same illness].
Topics: Arthritis, Rheumatoid; Azathioprine; Diagnosis, Differential; Humans; Immunosuppressive Agents; Knee | 1998 |
Scleritis and rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Age Factors; Arteritis; Arthritis, Rheumatoid; Azathioprine; Betamethas | 1971 |