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azathioprine and Rheumatism

azathioprine has been researched along with Rheumatism in 62 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"To discuss the relationship between the genotype of thiopurine methyltransferase (TPMT) and azathioprine tolerance in the patients with rheumatic diseases."7.74[Association between metabolic enzyme genotype of azathioprine and drug tolerance in patients with rheumatic diseases]. ( Huang, M; Li, H; Liang, LQ; Wang, YX; Yang, XY; Zhan, ZP, 2007)
"We report 14 cases of secondary myelodysplastic syndromes (sMDS) following treatment with azathioprine for non-malignant disorders."7.73Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7. ( Gattermann, N; Germing, U; Haas, R; Hildebrandt, B; Knipp, S; Richter, J, 2005)
" Methotrexate, azathioprine, mycophenolate mofetil, cyclosporin cyclophosphamide, chlorambucil, and other related drugs have potential benefits in the treatment of severe and/or recalcitrant rheumatic skin diseases."4.81Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders. ( Callen, JP, 2001)
"Azathioprine is a useful immunosuppressive agent in Beçhet's disease."3.77Immunosuppressive drug therapy for rheumatic disease. ( Bayliss, GE; McCune, WJ, 1991)
"To discuss the relationship between the genotype of thiopurine methyltransferase (TPMT) and azathioprine tolerance in the patients with rheumatic diseases."3.74[Association between metabolic enzyme genotype of azathioprine and drug tolerance in patients with rheumatic diseases]. ( Huang, M; Li, H; Liang, LQ; Wang, YX; Yang, XY; Zhan, ZP, 2007)
"We report 14 cases of secondary myelodysplastic syndromes (sMDS) following treatment with azathioprine for non-malignant disorders."3.73Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7. ( Gattermann, N; Germing, U; Haas, R; Hildebrandt, B; Knipp, S; Richter, J, 2005)
"We describe a 67-year-old white man with Wegener's granulomatosis who was treated with cyclophosphamide, then with azathioprine, and who subsequently developed cytomegalovirus retinitis."3.67Cytomegalovirus retinitis in rheumatic disease: a case report. ( Finan, MJ; Pressly, T; Roberts, R; Winkler, A, 1987)
" During treatment with the basic drugs: gold, D-penicillamine and chloroquine, pregnancy should be avoided."3.65[Problems of rheumatic therapy in pregnancy (author's transl)]. ( Bischof, P, 1976)
" In IBD, conventional weight-based dosing with thiopurines leads to an inadequate response in many patients."2.50The role of thiopurine metabolites in inflammatory bowel disease and rheumatological disorders. ( Friedman, AB; Gibson, PR; Sparrow, MP, 2014)
" TB risk was higher when anti-TNF agents were combined with methotrexate or azathioprine as compared with either controls (24/4241 versus 0/4673; OR 54; 95% CI 5."2.50Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents: a systematic review of randomized controlled trials. ( Armuzzi, A; Bruzzese, V; Diamanti, AP; Gatta, L; Hassan, C; Laganà, B; Lorenzetti, R; Migliore, A; Ridola, L; Zullo, A, 2014)
"Azathioprine is a valuable alternative to slow-acting antirheumatic drugs in older patients with rheumatoid arthritis."2.38Azathioprine, cyclophosphamide and chlorambucil. ( Bacon, PA; Luqmani, RA; Palmer, RG, 1990)
"Infection and disease exacerbation are the leading reasons for ICU admission in systemic rheumatic diseases."1.72Determination of the main causes, outcome, and prognostic factors of patients with rheumatologic diseases admitted to the medical intensive care unit in Southern Iran. ( Arjmand, M; Fallahi, MJ; Shahriarirad, R; Shenavandeh, S, 2022)
"As sarcoidosis is a mimicking disease, a good differential diagnosis should be made to avoid misdiagnosis and in order not to be late in diagnosis and treatment."1.72Perspective of sarcoidosis in terms of rheumatology: a single-center rheumatology clinic experience. ( Duruöz, MT; Esen, İ; Gezer, HH; Karabulut, Y; Öz, N, 2022)
"Short episodes of corticosteroids seem to be safe in HBV carriers, even in the presence of DMARDs, but lamivudine prophylaxis should be considered for patients exposed to biologicals or cyclophosphamide."1.43Safety of Corticosteroid Treatment in Rheumatologic Patients With Markers of Hepatitis B Viral Infection: Pilot Evaluation Study. ( Balbir-Gurman, A; Braun, M; Braun-Moscovici, Y; Markovits, D; Nahir, MA; Saadi, T, 2016)
"Azathioprine (AZA) is a commonly used drug for the management of various rheumatologic disorders."1.36Outcome of patients on azathioprine: a need for a better pre-treatment assessment and dosing guideline. ( Gow, PJ; Jabin, D; Kumar, S, 2010)
" Polymerase chain reaction (PCR) tests provide a sensitive, specific means of prospectively identifying these patients before AZA therapy and minimizing toxicity through dosage reduction."1.31Practical pharmacogenetics: the cost effectiveness of screening for thiopurine s-methyltransferase polymorphisms in patients with rheumatological conditions treated with azathioprine. ( Anis, AH; Esdaile, JM; Marra, CA, 2002)
"In addition to any increased risk of malignancy that may be conferred by individual rheumatic diseases, there is a further risk of specific types of malignancy that is related to the duration of exposure to immunosuppressive drugs."1.30Risk of developing certain malignancies is related to duration of immunosuppressive drug exposure in patients with rheumatic diseases. ( Asten, P; Barrett, J; Symmons, D, 1999)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199021 (33.87)18.7374
1990's12 (19.35)18.2507
2000's15 (24.19)29.6817
2010's10 (16.13)24.3611
2020's4 (6.45)2.80

Authors

AuthorsStudies
Arjmand, M1
Shahriarirad, R1
Shenavandeh, S1
Fallahi, MJ1
Karabulut, Y1
Öz, N1
Gezer, HH1
Esen, İ1
Duruöz, MT1
Yang, J1
Wang, P1
Qin, Z1
Jia, M1
Zhang, C1
Tian, X1
Zheng, Y1
Zhang, A1
Zhang, X1
Liu, S1
Broen, JCA1
van Laar, JM1
Su, SS1
Lin, YF1
Zhou, H1
Polk, BI1
Becker, ML2
Xuan, D1
Yu, Y1
Shao, L1
Wang, J1
Zhang, W1
Zou, H1
Friedman, AB1
Sparrow, MP1
Gibson, PR1
Lorenzetti, R1
Zullo, A1
Ridola, L1
Diamanti, AP1
Laganà, B1
Gatta, L1
Migliore, A1
Armuzzi, A1
Hassan, C1
Bruzzese, V1
Braun-Moscovici, Y1
Braun, M1
Saadi, T1
Markovits, D1
Nahir, MA1
Balbir-Gurman, A1
Mimori, T1
Jabin, D1
Kumar, S1
Gow, PJ1
Matsumoto, I1
Miller, AV1
Ranatunga, SK1
Siva, C1
Yokoyama, WM1
McLeod, HL3
Seidman, EG1
Furst, DE1
Marra, CA1
Esdaile, JM1
Anis, AH1
Mayer, DF1
Kushwaha, SS1
Mitnick, H1
Jacobowitz, G1
Krinsky, G1
Eberle, M1
Rosenzweig, B1
Willis, D1
Rockman, C1
Riles, T1
Knipp, S1
Hildebrandt, B1
Richter, J1
Haas, R1
Germing, U1
Gattermann, N1
Zhan, ZP2
Yang, XY2
Liang, LQ2
Wang, YX2
Huang, M2
Lian, F1
Payne, K1
Newman, W1
Fargher, E1
Tricker, K1
Bruce, IN1
Ollier, WE1
Glück, T1
Müller-Ladner, U1
Li, H1
Vroom, F1
van Roon, EN1
van den Berg, PB1
Brouwers, JR1
de Jong-van den Berg, LT1
Turner, RA1
Johnson, JA1
Semble, EL1
Jones, SM1
Calin, A1
Solinger, AM1
Hess, EV1
Bermas, BL1
Hill, JA1
Ramsey-Goldman, R1
Schilling, E1
McCune, J1
Singer, NG1
Black, AJ1
Capell, HA1
Powrie, RH1
Matowe, LK1
Pritchard, SC1
Collie-Duguid, ES1
Reid, DM1
Asten, P1
Barrett, J1
Symmons, D1
Ishioka, S1
Hiyama, K1
Sato, H1
Yamanishi, Y1
Kumagai, K1
Maeda, H1
Yamakido, M1
Ichikawa, Y1
Pickenpack, A1
Straub, RH1
Distler, O1
Hammond, A1
Oellerich, M1
Schölmerich, J1
Lang, B1
Schütz, E1
Balakrishnan, C1
Mangat, G1
Kalke, S1
Desai, D1
Joshi, A1
Deshpande, RB1
Joshi, VR1
Callen, JP1
Pirofsky, B1
Bardana, EJ1
Faust-Tinnefeldt, G1
Brinkrolf, H1
Mathies, H1
Evens, RP1
Bischof, P1
James, DG1
Friedmann, AI1
Graham, E1
McCune, WJ2
Friedman, AW1
Bayliss, GE1
Luqmani, RA1
Palmer, RG1
Bacon, PA1
Clements, PJ1
Davis, J1
O'Callaghan, JW1
Brooks, PM1
Winkler, A1
Finan, MJ1
Pressly, T1
Roberts, R1
Dugowson, CE1
Gilliland, BC1
Ostensen, M1
Husby, G1
Tsokos, GC1
Balow, JE1
Huskisson, EC1
Meadow, SR1
Glasgow, EF1
White, RH1
Moncrieff, MW1
Cameron, JS1
Ogg, CS1
Klein, G1
Fellner, S1
Fellner, R1
Rothermich, NO1
Mayr, E1
Kahn, MF1
Krampac, I1
Pavkovceková, O1
Démant, F1
Tischler, V1
Mydlík, M1
Jurkovic, I1
Prekop, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
he Efficacy and Safety of Combining Mycophenolate Mofetil With Methimazole on Remission of Newly Diagnosis Graves' Disease (3M-RGD Trial): an Open-label, Randomized Trial[NCT06068179]Phase 2/Phase 3205 participants (Anticipated)Interventional2023-10-08Not yet recruiting
Effectiveness of Mycophenolate Mofetil Combined With Tacrolimus for Steroid Tapering in Systemic Lupus Erythematosus: A Prospective, Random Control, Open-label, Single Center Clinical Trial[NCT05916781]Phase 4220 participants (Anticipated)Interventional2023-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

29 reviews available for azathioprine and Rheumatism

ArticleYear
Mycophenolate mofetil, azathioprine and tacrolimus: mechanisms in rheumatology.
    Nature reviews. Rheumatology, 2020, Volume: 16, Issue:3

    Topics: Antirheumatic Agents; Azathioprine; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Immunosupp

2020
Mycophenolate mofetil, azathioprine and tacrolimus: mechanisms in rheumatology.
    Nature reviews. Rheumatology, 2020, Volume: 16, Issue:3

    Topics: Antirheumatic Agents; Azathioprine; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Immunosupp

2020
Mycophenolate mofetil, azathioprine and tacrolimus: mechanisms in rheumatology.
    Nature reviews. Rheumatology, 2020, Volume: 16, Issue:3

    Topics: Antirheumatic Agents; Azathioprine; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Immunosupp

2020
Mycophenolate mofetil, azathioprine and tacrolimus: mechanisms in rheumatology.
    Nature reviews. Rheumatology, 2020, Volume: 16, Issue:3

    Topics: Antirheumatic Agents; Azathioprine; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Immunosupp

2020
Pharmacogenomics in childhood rheumatic disorders: a foundation for future individualized therapy.
    Discovery medicine, 2013, Volume: 16, Issue:90

    Topics: Antirheumatic Agents; Azathioprine; Biological Products; Biomarkers; Child; Genome, Human; Genotype;

2013
Hepatitis reactivation in patients with rheumatic diseases after immunosuppressive therapy--a report of long-term follow-up of serial cases and literature review.
    Clinical rheumatology, 2014, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Aged; Antiviral Agents; Arthritis, Rheumatoid; Azathioprine; Cohort Studies; Derm

2014
The role of thiopurine metabolites in inflammatory bowel disease and rheumatological disorders.
    International journal of rheumatic diseases, 2014, Volume: 17, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Drug Interactions; Gastrointestinal Agents; Humans;

2014
Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents: a systematic review of randomized controlled trials.
    Annals of medicine, 2014, Volume: 46, Issue:7

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Certolizumab Pe

2014
[Immunosuppressants].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:3

    Topics: Azathioprine; Calcineurin Inhibitors; Collagen Diseases; Cyclophosphamide; Cyclosporine; Humans; Imm

2009
[Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 4. Azathioprine].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2011, Oct-10, Volume: 100, Issue:10

    Topics: Azathioprine; Collagen Diseases; Humans; Immunosuppressive Agents; Rheumatic Diseases

2011
Immunotherapies in rheumatologic disorders.
    The Medical clinics of North America, 2012, Volume: 96, Issue:3

    Topics: Abatacept; Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monocl

2012
Pharmacogenomics in pediatric rheumatology.
    Current opinion in rheumatology, 2012, Volume: 24, Issue:5

    Topics: Antimetabolites; Antirheumatic Agents; Azathioprine; Biological Products; Child; Humans; Methotrexat

2012
Pharmacogenetics in rheumatology: the prospects and limitations of an emerging field.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:11

    Topics: Analgesics, Opioid; Antirheumatic Agents; Azathioprine; Drug Design; Drug Interactions; Drug-Related

2002
Pharmacogenetics for the individualization of treatment of rheumatic disorders using azathioprine.
    The Journal of rheumatology, 2002, Volume: 29, Issue:12

    Topics: Antirheumatic Agents; Azathioprine; Drug Monitoring; Genotype; Humans; Methyltransferases; Pharmacog

2002
Transplant immunosuppressant agents and their role in autoimmune rheumatic diseases.
    Current opinion in rheumatology, 2003, Volume: 15, Issue:3

    Topics: Autoimmune Diseases; Azathioprine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug

2003
[Do DMARDs contibute to impaired healing after surgery? Should they be discontinued before surgery?].
    Deutsche medizinische Wochenschrift (1946), 2007, Volume: 132, Issue:37

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Azathioprine; Biological Pro

2007
Effects of immunosuppressive drugs during pregnancy.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:12

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Azathioprine; Chlorambucil; Cyclophos

1995
Immunosuppressive drug use during pregnancy.
    Rheumatic diseases clinics of North America, 1997, Volume: 23, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Azathioprine; Chlorambucil; Cyclophosphamide; Cyclosporine; Female

1997
Immunosuppressive drug treatment.
    Current opinion in rheumatology, 1997, Volume: 9, Issue:3

    Topics: Azathioprine; Cyclophosphamide; Humans; Immunization; Immunocompromised Host; Immunosuppressive Agen

1997
Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders.
    Seminars in cutaneous medicine and surgery, 2001, Volume: 20, Issue:1

    Topics: Adult; Alkylating Agents; Antimetabolites; Azathioprine; Child; Chlorambucil; Cladribine; Cyclophosp

2001
Immunosuppressive therapy in rheumatic disease.
    The Medical clinics of North America, 1977, Volume: 61, Issue:2

    Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Dermatomyositis; Gr

1977
Immunosuppressive drug therapy for rheumatic disease.
    Current opinion in rheumatology, 1992, Volume: 4, Issue:3

    Topics: Azathioprine; Chlorambucil; Cyclosporine; Humans; Immunosuppressive Agents; Rheumatic Diseases

1992
Immunosuppressive drug therapy for rheumatic disease.
    Current opinion in rheumatology, 1991, Volume: 3, Issue:3

    Topics: Azathioprine; Cyclophosphamide; Cyclosporins; Humans; Immunosuppressive Agents; Mechlorethamine; Rhe

1991
Azathioprine, cyclophosphamide and chlorambucil.
    Bailliere's clinical rheumatology, 1990, Volume: 4, Issue:3

    Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Connective Tissue Diseases; Cyclophosphamide; Hum

1990
Cytotoxic drugs: their clinical application to the rheumatic diseases.
    Seminars in arthritis and rheumatism, 1986, Volume: 15, Issue:4

    Topics: Arthritis; Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Cell Division; Chemica

1986
Disease-modifying agents and immunosuppressive drugs in the elderly.
    Clinics in rheumatic diseases, 1986, Volume: 12, Issue:1

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cyclophosphami

1986
Management of rheumatoid arthritis.
    Disease-a-month : DM, 1986, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc

1986
Antirheumatic drug treatment during pregnancy and lactation.
    Scandinavian journal of rheumatology, 1985, Volume: 14, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Azathioprine; Chloroquine; Cyc

1985
Immunosuppressive agents and plasmapheresis in immunological disorders.
    Journal of immunopharmacology, 1985, Volume: 7, Issue:1

    Topics: Animals; Antigen-Antibody Complex; Autoantibodies; Azathioprine; Cyclophosphamide; Glucocorticoids;

1985
An updated look at antirheumatic drugs.
    The Medical clinics of North America, 1967, Volume: 51, Issue:5

    Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Azathioprine; Chloroquine; Cyclophosphamide; Gluco

1967
[Antirheumatics. 40].
    Pharmazeutische Praxis, 1969, Volume: 12

    Topics: Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Chlorambucil; Female; Humans; Immunosu

1969
[The immunodepressive agents. II. Immunodepressive agents in rheumatic diseases].
    La Presse medicale, 1967, May-13, Volume: 75, Issue:23

    Topics: Azathioprine; Chlorambucil; Humans; Immunosuppressive Agents; Rheumatic Diseases; Thiotepa

1967

Trials

5 trials available for azathioprine and Rheumatism

ArticleYear
Safety and efficacy of an intravenous loading dose of azathioprine for treatment of non-TPMT-deficient patients with rheumatic diseases.
    Rheumatology (Oxford, England), 2000, Volume: 39, Issue:12

    Topics: Antirheumatic Agents; Azathioprine; Dose-Response Relationship, Drug; Drug Administration Schedule;

2000
Immunosuppressive therapy in rheumatic disease.
    The Medical clinics of North America, 1977, Volume: 61, Issue:2

    Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Dermatomyositis; Gr

1977
[Azathioprine in long-term therapy of inflammatory rheumatic diseases. Variability of laboratory chemical parameters].
    Die Medizinische Welt, 1978, Feb-24, Volume: 29, Issue:8

    Topics: Alkaline Phosphatase; Azathioprine; Blood Cell Count; Blood Sedimentation; gamma-Glutamyltransferase

1978
Immunosuppressive drug therapy for rheumatic disease.
    Current opinion in rheumatology, 1991, Volume: 3, Issue:3

    Topics: Azathioprine; Cyclophosphamide; Cyclosporins; Humans; Immunosuppressive Agents; Mechlorethamine; Rhe

1991
[Indomethacin in rheumatic diseases with special reference to ophthalmologic studies].
    Medizinische Klinik, 1972, Feb-25, Volume: 67, Issue:8

    Topics: Allopurinol; Arthritis, Rheumatoid; Azathioprine; Blood Cells; Capsules; Clinical Trials as Topic; E

1972

Other Studies

30 other studies available for azathioprine and Rheumatism

ArticleYear
Determination of the main causes, outcome, and prognostic factors of patients with rheumatologic diseases admitted to the medical intensive care unit in Southern Iran.
    Clinical rheumatology, 2022, Volume: 41, Issue:12

    Topics: Arthritis, Rheumatoid; Azathioprine; Disease Progression; Dyspnea; Female; Hospital Mortality; Human

2022
Perspective of sarcoidosis in terms of rheumatology: a single-center rheumatology clinic experience.
    Rheumatology international, 2022, Volume: 42, Issue:12

    Topics: Adrenal Cortex Hormones; Ambulatory Care Facilities; Anti-Inflammatory Agents, Non-Steroidal; Arthri

2022
    Genetic testing and molecular biomarkers, 2019, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Alleles; Asian People; Azathioprine; Biomarkers; Child; Female; Genetic Pre

2019
Association of thiopurine S-methyltransferase and NUDT15 polymorphisms with azathioprine-induced myelotoxicity in Chinese patients with rheumatological disease.
    Chinese medical journal, 2020, Apr-20, Volume: 133, Issue:8

    Topics: Adolescent; Adult; Asian People; Azathioprine; Humans; Immunosuppressive Agents; Methyltransferases;

2020
Safety of Corticosteroid Treatment in Rheumatologic Patients With Markers of Hepatitis B Viral Infection: Pilot Evaluation Study.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2016, Volume: 22, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Aged; Alanine Transaminase; Antirheumatic Agents; Azathioprine; Cycl

2016
Outcome of patients on azathioprine: a need for a better pre-treatment assessment and dosing guideline.
    The New Zealand medical journal, 2010, Oct-15, Volume: 123, Issue:1324

    Topics: Antirheumatic Agents; Azathioprine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Follo

2010
Practical pharmacogenetics: the cost effectiveness of screening for thiopurine s-methyltransferase polymorphisms in patients with rheumatological conditions treated with azathioprine.
    The Journal of rheumatology, 2002, Volume: 29, Issue:12

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cost-Benefit Analysis; Decision Support T

2002
Periaortitis: gadolinium-enhanced magnetic resonance imaging and response to therapy in four patients.
    Annals of vascular surgery, 2004, Volume: 18, Issue:1

    Topics: Aged; Anti-Inflammatory Agents; Arteriosclerosis; Azathioprine; Contrast Media; Female; Gadolinium D

2004
Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7.
    Haematologica, 2005, Volume: 90, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Cell Transformation, Neoplastic;

2005
[The profile and clinical significance of azathioprine metabolic enzymes activity in rheumatological patients].
    Zhonghua nei ke za zhi, 2006, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow; Drug Tolerance; Erythrocytes; Female; Follow-Up Studie

2006
TPMT testing in rheumatology: any better than routine monitoring?
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:5

    Topics: Antirheumatic Agents; Azathioprine; Drug Administration Schedule; Drug Monitoring; Humans; Immunosup

2007
[Association between metabolic enzyme genotype of azathioprine and drug tolerance in patients with rheumatic diseases].
    Zhonghua yi xue za zhi, 2007, Jul-03, Volume: 87, Issue:25

    Topics: Adolescent; Adult; Analysis of Variance; Azathioprine; Drug Resistance; Female; Gene Frequency; Geno

2007
Prescribing of sulfasalazine, azathioprine and methotrexate round pregnancy--a descriptive study.
    Pharmacoepidemiology and drug safety, 2008, Volume: 17, Issue:1

    Topics: Antirheumatic Agents; Azathioprine; Databases, Factual; Drug Prescriptions; Drug Therapy, Combinatio

2008
Antirheumatic drug effects on neutrophil response to chemotactic factors: a comparison of analytical techniques.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1983, Volume: 173, Issue:2

    Topics: Aspirin; Azathioprine; Chemotactic Factors; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug;

1983
The monitoring of patients on disease-modifying antirheumatoid drugs.
    British journal of rheumatology, 1993, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents; Azathioprine; Cyclophosphamide; Humans; Methotrexate; Rheumatic Diseases

1993
Rheumatic diseases and AIDS--is the association real?
    The Journal of rheumatology, 1993, Volume: 20, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Azathioprine; Female; Humans; Male; Muscular Diseases; Pa

1993
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine.
    Annals of internal medicine, 1998, Nov-01, Volume: 129, Issue:9

    Topics: Adult; Antirheumatic Agents; Azathioprine; Female; Hematologic Diseases; Heterozygote; Humans; Male;

1998
Risk of developing certain malignancies is related to duration of immunosuppressive drug exposure in patients with rheumatic diseases.
    The Journal of rheumatology, 1999, Volume: 26, Issue:8

    Topics: Aged; Aged, 80 and over; Azathioprine; Europe; Female; Follow-Up Studies; Humans; Immunosuppressive

1999
Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese.
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:12

    Topics: Azathioprine; Genotype; Humans; Immunosuppressive Agents; Japan; Methyltransferases; Mutation; Rheum

1999
Single nucleotide polymorphism to disclose severe side-effects or proper dosage for each patient.
    Internal medicine (Tokyo, Japan), 2000, Volume: 39, Issue:7

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Methyltransferases; Mutation; Polymorphism, Single N

2000
The spectrum of chronic autoimmune hepatitis.
    The Journal of the Association of Physicians of India, 1998, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Autoantibodies; Azathioprine; Biopsy, Needle; Chronic Disease; Female; Hepatitis

1998
[Azathioprine in rheumatology].
    Fortschritte der Medizin, 1979, Dec-20, Volume: 97, Issue:48

    Topics: Arthritis, Rheumatoid; Azathioprine; Chromosome Aberrations; Humans; Immunosuppression Therapy; Lupu

1979
Antirheumatic agents.
    The Journal of the Maine Medical Association, 1979, Volume: 70, Issue:4

    Topics: Adrenal Cortex Hormones; Antimalarials; Aspirin; Azathioprine; Chloroquine; Cyclophosphamide; Gold;

1979
[Problems of rheumatic therapy in pregnancy (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, Oct-08, Volume: 118, Issue:41

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Azathioprine; Chloroquine; Female; Fetal Diseases

1976
Uveitis. A series of 368 patients.
    Transactions of the ophthalmological societies of the United Kingdom, 1976, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Aged; Antigen-Antibody Complex; Autoantibodies; Azathioprine; Child; Child, Presc

1976
Cytomegalovirus retinitis in rheumatic disease: a case report.
    Arthritis and rheumatism, 1987, Volume: 30, Issue:1

    Topics: Adult; Azathioprine; Cyclophosphamide; Cytomegalovirus Infections; Granulomatosis with Polyangiitis;

1987
Recent drugs and the rheumatic diseases.
    Reports on rheumatic diseases, 1974, Issue:54

    Topics: Acetaminophen; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-

1974
Schönlein-Henoch nephritis.
    The Quarterly journal of medicine, 1972, Volume: 41, Issue:163

    Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Biopsy; Child; Child, Preschool; Cyclophosphamide

1972
[Positive and negative effects of cytostatic therapy in rheumatic patients].
    Reumatizam, 1970, Volume: 17, Issue:2

    Topics: Antineoplastic Agents; Azathioprine; Chlorambucil; Cyclophosphamide; Humans; Mercaptopurine; Methotr

1970
[Immunosuppressive therapy of kidney lesio in Schönlein-Henoch purpura].
    Casopis lekaru ceskych, 1970, Volume: 109, Issue:50

    Topics: Azathioprine; Child; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Purpura; Rheum

1970