Page last updated: 2024-10-23

azathioprine and Respiratory Tract Diseases

azathioprine has been researched along with Respiratory Tract Diseases in 10 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Respiratory Tract Diseases: Diseases involving the RESPIRATORY SYSTEM.

Research Excerpts

ExcerptRelevanceReference
"Eighty-five patients with Wegener's granulomatosis were studied for 21 years at the National Institutes of Health."3.75Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. ( Fauci, AS; Haynes, BF; Katz, P; Wolff, SM, 1983)
"Since relapses are frequent, these patients should be evaluated frequently."1.31Wegener granulomatosis in children and young adults. A case study of ten patients. ( Gothefors, L; Malmer, B; Müller Wiefel, DE; Nilsson, K; Stegmayr, BG; Sundelin, B, 2000)
"In the azathioprine group, respiratory infections accounted for 24 of 60 (40%) infections."1.27Respiratory complications of cardiac transplantation. ( Drusin, R; Enson, Y; Reemtsma, K; Rose, EA; Schulman, LL; Smith, CR, 1988)
"20 patients with myasthenia gravis (MG), refractory to anticholinesterase and steroid therapy, underwent plasma exchange therapy combined with immunosuppressive drugs and lymphocytapheresis."1.26Plasma exchange combined with cytotoxic drugs and lymphocytapheresis for myasthenia gravis. ( Cornelio, F; Forlani, G; Garelli, S; Pelucchetti, D; Valbonesi, M; Zerbi, D, 1982)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Shimizu, J1
Yamano, Y1
Kawahata, K1
Suzuki, N1
Lynch, JP1
Tazelaar, H1
Fauci, AS2
Haynes, BF1
Katz, P1
Wolff, SM2
Valbonesi, M1
Garelli, S1
Zerbi, D1
Forlani, G1
Cornelio, F1
Pelucchetti, D1
Shumway, SJ1
Hertz, MI1
Maynard, R1
Kshettry, VR1
Bolman, RM1
Stegmayr, BG1
Gothefors, L1
Malmer, B1
Müller Wiefel, DE1
Nilsson, K1
Sundelin, B1
Schulman, LL1
Smith, CR1
Drusin, R1
Rose, EA1
Enson, Y1
Reemtsma, K1
Horn, RG1
Dale, DC1
Harrison, DF1
Hagedorn, M1
Maas, D1
Bilger, R1
Mittermayer, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901]Phase 260 participants Interventional1999-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for azathioprine and Respiratory Tract Diseases

ArticleYear
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
    Annals of internal medicine, 1983, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati

1983

Trials

1 trial available for azathioprine and Respiratory Tract Diseases

ArticleYear
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
    Annals of internal medicine, 1983, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati

1983

Other Studies

9 other studies available for azathioprine and Respiratory Tract Diseases

ArticleYear
Nationwide cross-sectional survey of patients with relapsing polychondritis in 2019 demonstrates reduction of airway involvement compared with that in 2009.
    Scientific reports, 2022, 01-10, Volume: 12, Issue:1

    Topics: Adult; Azathioprine; Cross-Sectional Studies; Cyclophosphamide; Female; Humans; Immunosuppressive Ag

2022
Wegener granulomatosis (granulomatosis with polyangiitis): evolving concepts in treatment.
    Seminars in respiratory and critical care medicine, 2011, Volume: 32, Issue:3

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Cy

2011
Plasma exchange combined with cytotoxic drugs and lymphocytapheresis for myasthenia gravis.
    Vox sanguinis, 1982, Volume: 43, Issue:3

    Topics: Azathioprine; Cell Separation; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Leukapher

1982
Airway complications after lung and heart-lung transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Antilymphocyte Serum; Azathioprine; Cyclosporine; Heart-Lung Transplantation; Humans; Immunosuppress

1993
Wegener granulomatosis in children and young adults. A case study of ten patients.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Antigen-Antibody Reactions; Azathioprine; Child; Cyclophosphamide; Disease Progre

2000
Respiratory complications of cardiac transplantation.
    The American journal of the medical sciences, 1988, Volume: 296, Issue:1

    Topics: Adult; Azathioprine; Cyclosporins; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; P

1988
Wegener's granulomatosis.
    Annals of internal medicine, 1974, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Diagnosis, Differe

1974
Non-healing granulomata of the upper respiratory tract.
    British medical journal, 1974, Oct-26, Volume: 4, Issue:5938

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Blood Sedimentation; Child; Female;

1974
[Papulosis atrophicans maligna (Köhlmeier-Degos) and Wegener's granulomatosis in a sister and brother (author's transl)].
    Medizinische Klinik, 1974, May-24, Volume: 69, Issue:21

    Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Cyclophosphamide; Diet Therapy; Female; Glutens; Granul

1974