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azathioprine and Reperfusion Injury

azathioprine has been researched along with Reperfusion Injury in 8 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"They were subjected to spinal cord ischemia by clamping the abdominal aorta for 45 min."5.32Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury. ( Ak, K; Akgun, S; Arsan, S; Civelek, A; Isbir, SC; Kurtkaya, O; Sav, A; Tekeli, A, 2004)
"They were subjected to spinal cord ischemia by clamping the abdominal aorta for 45 min."1.32Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury. ( Ak, K; Akgun, S; Arsan, S; Civelek, A; Isbir, SC; Kurtkaya, O; Sav, A; Tekeli, A, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Askar, I1
Bozkurt, M1
Akgun, S1
Tekeli, A1
Kurtkaya, O1
Civelek, A1
Isbir, SC1
Ak, K1
Arsan, S1
Sav, A1
Lang-Lazdunski, L1
Kawano, K3
Kim, YI3
Ono, M2
Goto, S2
Kai, T2
Kobayashi, M3
Matsuda, T1
Yamaguchi, Y1
Matsumura, F1
Akizuki, E1
Okabe, K1
Liang, J1
Ohshiro, H1
Ichiguchi, O1
Yamada, S1
Mori, K1
Ogawa, M1
Ishii, T1
Tatsuma, T1
Akimaru, K1
Shouji, T1
Iwao, Y1

Other Studies

8 other studies available for azathioprine and Reperfusion Injury

ArticleYear
Protective effects of immunosuppressants and steroids against ischemia-reperfusion injury in cremaster muscle flap at microcirculatory level.
    Microsurgery, 2002, Volume: 22, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Cyclosporine; Dexamethasone; Disease Models, Animal

2002
Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 25, Issue:1

    Topics: Animals; Azathioprine; Carnitine; Drug Therapy, Combination; Immunohistochemistry; Immunosuppressive

2004
About the neuroprotective effects of FK-506, l-carnitine and azathioprine on spinal cord ischemia-reperfusion injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 25, Issue:6

    Topics: Animals; Azathioprine; Carnitine; Neuroprotective Agents; Rats; Reperfusion Injury; Spinal Cord Isch

2004
Evidence that both cyclosporin and azathioprine prevent warm ischemia reperfusion injury to the rat liver.
    Transplant international : official journal of the European Society for Organ Transplantation, 1993, Volume: 6, Issue:6

    Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Azathioprine; Cycl

1993
Immunosuppressants decrease neutrophil chemoattractant and attenuate ischemia/reperfusion injury of the liver in rats.
    The Journal of trauma, 1998, Volume: 44, Issue:3

    Topics: Animals; Azathioprine; Cyclosporine; Drug Evaluation, Preclinical; Immunosuppressive Agents; Interle

1998
Immunodepressants ameliorate normothermic ischemia injury to the rat liver by down-regulating tumor necrosis factor, not by alleviation of lipid peroxidative injury.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1

    Topics: Alanine Transaminase; Animals; Azathioprine; Cyclosporine; Female; Immunosuppressive Agents; Ischemi

1994
[Pathology of the grafted liver].
    Nihon Ika Daigaku zasshi, 1992, Volume: 59, Issue:5

    Topics: Azathioprine; Cyclosporine; Graft Rejection; Hepatitis, Viral, Human; Humans; Liver; Liver Transplan

1992
Amelioration of 3.5-hour warm ischemia time for pig livers by cyclosporine pretherapy, compared with azathioprine.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 1

    Topics: Animals; Azathioprine; Cyclosporins; Drug Administration Schedule; Female; Liver Circulation; Liver

1991