azathioprine has been researched along with Purpura, Thrombotic Thrombocytopenic in 11 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Purpura, Thrombotic Thrombocytopenic: An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of thrombotic thrombocytopenic purpura (TTP) with plasma exchange has reduced mortality rates from 90% in untreated cases to less than 20%." | 2.41 | Frequently relapsing thrombotic thrombocytopenic purpura treated with cytotoxic immunosuppressive therapy. ( Allan, DS; Clark, WF; Kovacs, MJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bichard, C | 1 |
| Mancini, I | 1 |
| Agosti, P | 1 |
| Capecchi, M | 1 |
| De Leo, P | 1 |
| Arcudi, S | 1 |
| Ferrari, B | 1 |
| Trisolini, SM | 1 |
| Longu, F | 1 |
| Fozza, C | 1 |
| Artoni, A | 1 |
| Peyvandi, F | 1 |
| Shirai, T | 1 |
| Ishii, T | 1 |
| Watanabe, R | 1 |
| Tajima, Y | 1 |
| Fujii, H | 1 |
| Takasawa, N | 1 |
| Sato, H | 1 |
| Harigae, H | 1 |
| Ozdogu, H | 1 |
| Boga, C | 1 |
| Kizilkilic, E | 1 |
| Yeral, M | 1 |
| Kozanoglu, I | 1 |
| Karatas, M | 1 |
| Kapfhammer, HP | 1 |
| Heigl, F | 1 |
| Bell, WR | 1 |
| Allan, DS | 1 |
| Kovacs, MJ | 1 |
| Clark, WF | 1 |
| Humblot, S | 1 |
| Martin, T | 1 |
| Pasquali, JL | 1 |
| Korganow, AS | 1 |
| Moake, JL | 1 |
| Rudy, CK | 1 |
| Troll, JH | 1 |
| Schafer, AI | 1 |
| Weinstein, MJ | 1 |
| Colannino, NM | 1 |
| Hong, SL | 1 |
| Goebel, KM | 1 |
| Gassel, WD | 1 |
| Goebel, FD | 1 |
| Cameron, JS | 1 |
| Ogg, CS | 1 |
| Taglioretti, D | 1 |
| Giangrande, A | 1 |
1 review available for azathioprine and Purpura, Thrombotic Thrombocytopenic
| Article | Year |
|---|---|
Frequently relapsing thrombotic thrombocytopenic purpura treated with cytotoxic immunosuppressive therapy.
Topics: Adult; Azathioprine; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Middle Aged; Platel | 2001 |
10 other studies available for azathioprine and Purpura, Thrombotic Thrombocytopenic
| Article | Year |
|---|---|
Efficacy and safety of azathioprine during remission of immune-mediated thrombotic thrombocytopenic purpura.
Topics: ADAM Proteins; ADAMTS13 Protein; Azathioprine; Humans; Purpura, Thrombotic Thrombocytopenic | 2022 |
Thrombotic microangiopathy presenting with a considerable accumulation of ascites: a case report.
Topics: Ascites; Azathioprine; Blood Transfusion; Cyclophosphamide; Humans; Immunosuppressive Agents; Kidney | 2011 |
A dramatic response to rituximab in a patient with resistant thrombotic thrombocytopenic purpura (TTP) who developed acute stroke.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Azathio | 2007 |
[Bipolar affective disorder and neuropsychiatric complications in a chronic course of thrombotic thrombocytopenic purpura. A case report].
Topics: Adult; Azathioprine; Bipolar Disorder; Combined Modality Therapy; Female; Humans; Neurocognitive Dis | 1993 |
Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome relapse: frequency, pathogenesis, and meaning.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Blood Transfusion; Female; Hematocrit; Hemoglobins; He | 1997 |
Blood coagulation disorders during primary cytomegalovirus infection.
Topics: Adult; Azathioprine; Blood Coagulation Tests; Colitis, Ulcerative; Cytomegalovirus Infections; Disse | 2001 |
Therapy of chronic relapsing thrombotic thrombocytopenic purpura with prednisone and azathioprine.
Topics: Azathioprine; Chronic Disease; Drug Therapy, Combination; Female; Humans; Middle Aged; Prednisone; P | 1985 |
Evaluation of azathioprine in autoimmune thrombocytopenia and lupus erythematosus.
Topics: Adult; Autoimmune Diseases; Azathioprine; Blood Cell Count; Female; Humans; Immunity, Cellular; Immu | 1973 |
Rapidly progressive glomerulonephritis with extensive crescents.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anticoagulants; Azathioprine; Child; Child, Presch | 1973 |
Azathioprine in myeloproliferative and autoimmune disorders.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Azathioprine; Colitis, | 1968 |