azathioprine has been researched along with Purpura, Thrombocytopenic, Idiopathic in 43 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Purpura, Thrombocytopenic, Idiopathic: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A diagnosis of autoimmune thrombocytopenia was made." | 6.44 | [Successful treatment with azathioprine for autoimmune thrombocytopenia developing after autologous peripheral blood stem cell transplantation]. ( Fujita, H; Hashimoto, H; Kurata, M; Maeda, A; Mastusita, A; Mori, M; Nagai, K; Nagai, Y; Tabata, S; Takahashi, T; Togami, K, 2007) |
| "First-line AZA plus prednisone realizes a better hematological response and relapse-free duration with acceptable adverse events compared to prednisone alone in ANA-positive ITP patients." | 5.91 | Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study. ( Chen, X; Dong, Z; Ma, L; Su, J; Wang, Q; Xiao, P; Xu, M, 2023) |
| "We report on four cases (three women, one man, age at diagnosis 26-61 years) with severe autoimmune thrombocytopenia (AITP) who were refractory to initial steroid therapy (n = 4), to subsequent splenectomy (n = 2), azathioprine (n = 1), and cyclosporine (n = 1)." | 3.74 | Late spontaneous remissions in severe adult autoimmune thrombocytopenia. ( Lechner, K; Pabinger, I; Panzer, S; Simanek, R, 2007) |
| "Only few cases of vaccine-induced immune thrombocytopenia or immune hemolysis have been reported so far." | 3.01 | Relapse of Evans syndrome following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine: case report and literature review. ( Cvetković, M; Mitrović, M; Pantić, N; Pravdić, Z; Sabljić, N; Suvajdžić-Vuković, N; Virijević, M, 2023) |
| "Patients with severe immune thrombocytopenic purpura (ITP) may require an acute increase in the platelet count for surgery or ongoing hemorrhage as well as long-term maintenance treatment." | 2.73 | Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP). ( Boruchov, DM; Bussel, JB; Driscoll, MC; Gururangan, S, 2007) |
| "A diagnosis of autoimmune thrombocytopenia was made." | 2.44 | [Successful treatment with azathioprine for autoimmune thrombocytopenia developing after autologous peripheral blood stem cell transplantation]. ( Fujita, H; Hashimoto, H; Kurata, M; Maeda, A; Mastusita, A; Mori, M; Nagai, K; Nagai, Y; Tabata, S; Takahashi, T; Togami, K, 2007) |
| "First-line AZA plus prednisone realizes a better hematological response and relapse-free duration with acceptable adverse events compared to prednisone alone in ANA-positive ITP patients." | 1.91 | Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study. ( Chen, X; Dong, Z; Ma, L; Su, J; Wang, Q; Xiao, P; Xu, M, 2023) |
| "Selection of patients with chronic immune thrombocytopenia from the French national prospective cohort of pediatric autoimmune cytopenia OBS'CEREVANCE and VIGICAIRE study, treated by splenectomy, hydroxychloroquine, azathioprine, or rituximab as a first second-line treatment." | 1.62 | Prospective Evaluation of the First Option, Second-Line Therapy in Childhood Chronic Immune Thrombocytopenia: Splenectomy or Immunomodulation. ( Abou Chahla, W; Aladjidi, N; Armari-Alla, C; Barlogis, V; Bayart, S; Bertrand, Y; Cheikh, N; Ducassou, S; Fernandes, H; Guitton, C; Kherfellah, D; Laghouati, S; Leblanc, T; Leverger, G; Pasquet, M; Pellier, I; Savel, H; Thiébaut, R; Thomas, C; Vassal, G, 2021) |
| "Severe immune thrombocytopenia complicating pregnancy may require treatment beyond first-line medications (intravenous immunoglobulins or corticosteroids), but there is a paucity of literature on the use of such second-line agents in pregnancy." | 1.56 | Multidrug Therapy for Refractory Immune Thrombocytopenia in Pregnancy. ( Chan, R; Chon, AH; Kwong, K; Lee, RH; Weitz, IC; Wertheimer, FB, 2020) |
| "Azathioprine (AZA) is a commonly used immunosuppressant in patients with autoimmune diseases." | 1.56 | NUDT15 polymorphism explains serious toxicity to azathioprine in Indian patients with chronic immune thrombocytopenia and autoimmune hemolytic anemia: a case series. ( Balasubramanian, P; Devasia, AJ; George, B; Illangeswaran, RSS; Raj, IX, 2020) |
| "Many patients with immune thrombocytopenia (ITP) may require special attention and long-term treatment." | 1.48 | Efficacy and tolerability of old and new drugs used in the treatment of immune thrombocytopenia: Results from a long-term observation in clinical practice. ( Aboud, N; Depré, F; Mayer, B; Salama, A, 2018) |
| "Interstitial lung disease is a rare but recognised complication of rituximab but has been rarely reported in the setting of ITP." | 1.38 | Rituximab-induced interstitial lung disease in a patient with immune thrombocytopenia purpura. ( Berkahn, L; Child, N; O'Carroll, M, 2012) |
| "Patients with primary immune thrombocytopenia (ITP) may require treatment to reduce the risk of serious bleeding if platelets remain consistently below 30 × 10(9)/L." | 1.36 | Should medical treatment options be exhausted before splenectomy is performed in adult ITP patients? A debate. ( Newland, A; Pabinger, I; Stasi, R; Thornton, P, 2010) |
| "Acute interstitial pneumonitis is the main pulmonary side effect during MTX treatment." | 1.35 | [Pneumonitis associated to methotrexate]. ( Marquina Barcos, A; Monón Ballarín, S; Mozota Duarte, J; Ruiz-Ruiz, FJ; Sáenz Abad, D, 2008) |
| "One patient had immune thrombocytopenia and neutropenia." | 1.33 | Rituximab chimeric anti-CD20 monoclonal antibody treatment for adult refractory idiopathic thrombocytopenic purpura. ( Andersen, I; Andersen, TM; Birgens, HS; Bjerrum, OW; Braendstrup, P; Clausen, NT; Hansen, PB; Hasselbalch, HC; Jensen, BA; Nielsen, OJ; Pedersen, BB; Peterslund, NA; Plesner, T; Schmidt, K, 2005) |
| "Sarcoidosis is a chronic granulomatous disorder characterized by multisystem involvement, however, symptomatic thrombocytopenia as a presenting manifestation is rare." | 1.31 | Thrombocytopenia as the presenting manifestation of sarcoidosis. ( Agarwal, A; Agarwal, V; Gupta, RK; Mishra, R; Pal, S, 2002) |
| "Autopsy revealed that the cervical cancer was the primary origin of the liver tumors." | 1.30 | [Rapidly progressive irradiated cervical cancer that metastasized to the liver during therapy for idiopathic thrombocytopenic purpura]. ( Kariya, K; Kawamura, S; Munakata, A; Nakahata, R; Takami, H; Tamai, Y; Tsushima, K; Yoshimura, T, 1999) |
| "A young patient developed chronic idiopathic thrombocytopenic purpura." | 1.28 | Defect of platelet aggregation and adhesion induced by autoantibodies against platelet glycoprotein IIIa. ( Balduini, CL; Bellotti, V; Bertolino, G; Mazzini, G; Noris, P; Piovella, F; Samaden, A; Sinigaglia, F; Torti, M, 1992) |
| "The treatment with azathioprine and prednisolone after IVIG appears to be effective in maintenance of platelet counts." | 1.28 | [Effects of maintenance treatment after high-dose intravenous gamma-globulin for idiopathic thrombocytopenic purpura]. ( Fujitake, H; Im, T; Kageyama, T; Kawagoe, H; Kokawa, T; Nomura, S; Ohyabu, H; Park, K; Tatsumi, N; Yasunaga, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.33) | 18.7374 |
| 1990's | 4 (9.30) | 18.2507 |
| 2000's | 17 (39.53) | 29.6817 |
| 2010's | 12 (27.91) | 24.3611 |
| 2020's | 9 (20.93) | 2.80 |
| Authors | Studies |
|---|---|
| Mahajna, H | 3 |
| Verstockt, B | 3 |
| Bergemalm, D | 3 |
| Castiglione, F | 3 |
| Rodríguez-Moranta, F | 3 |
| Savarino, E | 3 |
| Hoentjen, F | 3 |
| Bessissow, T | 3 |
| Pokryszka, J | 3 |
| Cremer, A | 3 |
| Eder, P | 3 |
| Truyens, M | 3 |
| Yerushalmy-Feler, A | 3 |
| García, MJ | 3 |
| Kopylov, U | 3 |
| Su, J | 1 |
| Xu, M | 1 |
| Dong, Z | 1 |
| Wang, Q | 1 |
| Ma, L | 1 |
| Xiao, P | 1 |
| Chen, X | 1 |
| Cvetković, M | 1 |
| Pantić, N | 1 |
| Virijević, M | 1 |
| Pravdić, Z | 1 |
| Sabljić, N | 1 |
| Mitrović, M | 1 |
| Suvajdžić-Vuković, N | 1 |
| Velayos Jiménez, B | 1 |
| Cuello García, R | 1 |
| Del Olmo Martínez, L | 1 |
| Macho Conesa, A | 1 |
| Fernández Salazar, L | 1 |
| Bm, S | 1 |
| Toshniwal, M | 1 |
| Bhattacharya, M | 1 |
| Jakkal, D | 1 |
| Chon, AH | 1 |
| Chan, R | 1 |
| Lee, RH | 1 |
| Kwong, K | 1 |
| Wertheimer, FB | 1 |
| Weitz, IC | 1 |
| Devasia, AJ | 1 |
| Illangeswaran, RSS | 1 |
| Raj, IX | 1 |
| George, B | 1 |
| Balasubramanian, P | 1 |
| Fanouriakis, A | 1 |
| Tziolos, N | 1 |
| Bertsias, G | 1 |
| Boumpas, DT | 1 |
| Ducassou, S | 1 |
| Fernandes, H | 1 |
| Savel, H | 1 |
| Bertrand, Y | 1 |
| Leblanc, T | 1 |
| Abou Chahla, W | 1 |
| Pasquet, M | 1 |
| Leverger, G | 1 |
| Barlogis, V | 1 |
| Thomas, C | 1 |
| Bayart, S | 1 |
| Pellier, I | 1 |
| Armari-Alla, C | 1 |
| Guitton, C | 1 |
| Cheikh, N | 1 |
| Kherfellah, D | 1 |
| Vassal, G | 1 |
| Thiébaut, R | 1 |
| Laghouati, S | 1 |
| Aladjidi, N | 1 |
| Brunet, E | 1 |
| Martínez de Sola, M | 1 |
| Garcia-Iglesias, P | 1 |
| Calvet, X | 1 |
| Depré, F | 1 |
| Aboud, N | 1 |
| Mayer, B | 1 |
| Salama, A | 1 |
| Mizuno, S | 1 |
| Naganuma, M | 1 |
| Kanai, T | 1 |
| Chang, H | 1 |
| Tang, TC | 1 |
| Hung, YS | 1 |
| Li, PL | 1 |
| Kuo, MC | 1 |
| Wu, JH | 1 |
| Wang, PN | 1 |
| Lougaris, V | 1 |
| Baronio, M | 1 |
| Gazzurelli, L | 1 |
| Lorenzini, T | 1 |
| Fuoti, M | 1 |
| Moratto, D | 1 |
| Bozzola, A | 1 |
| Ricci, C | 1 |
| Bondioni, MP | 1 |
| Ravelli, A | 1 |
| Villanacci, V | 1 |
| Plebani, A | 1 |
| Kumwenda, JJ | 1 |
| Hsiao, CH | 1 |
| Tseng, KC | 1 |
| Tseng, CW | 1 |
| Tung, CH | 1 |
| Fan, Y | 1 |
| Chang, NB | 1 |
| Xing, BL | 1 |
| Li, YM | 1 |
| Pei, L | 1 |
| Li, JT | 1 |
| Sabnani, I | 1 |
| Tsang, P | 1 |
| Valdivieso, R | 1 |
| Cevallos, F | 1 |
| Caballero, MT | 1 |
| Quirce, S | 1 |
| Arnold, DM | 1 |
| Nazi, I | 1 |
| Santos, A | 1 |
| Chan, H | 1 |
| Heddle, NM | 1 |
| Warkentin, TE | 1 |
| Kelton, JG | 1 |
| McDonald, EJ | 1 |
| Butler, A | 1 |
| Stasi, R | 1 |
| Newland, A | 1 |
| Thornton, P | 1 |
| Pabinger, I | 2 |
| Child, N | 1 |
| O'Carroll, M | 1 |
| Berkahn, L | 1 |
| Uygur-Bayramiçli, O | 1 |
| Aydin, D | 1 |
| Ak, O | 1 |
| Karadayi, N | 1 |
| RICHMOND, J | 1 |
| WOODRUFF, MF | 1 |
| CUMMING, RA | 1 |
| DONALD, KW | 1 |
| Imbach, P | 1 |
| Tsai, CL | 1 |
| Lu, TC | 1 |
| Chen, WJ | 1 |
| Knecht, H | 1 |
| Baumberger, M | 1 |
| Tobòn, A | 1 |
| Steck, A | 1 |
| Treppendahl, MB | 1 |
| Nielsen, OJ | 2 |
| Braendstrup, P | 1 |
| Bjerrum, OW | 1 |
| Jensen, BA | 1 |
| Clausen, NT | 1 |
| Hansen, PB | 1 |
| Andersen, I | 1 |
| Schmidt, K | 1 |
| Andersen, TM | 1 |
| Peterslund, NA | 1 |
| Birgens, HS | 1 |
| Plesner, T | 1 |
| Pedersen, BB | 1 |
| Hasselbalch, HC | 1 |
| Simanek, R | 1 |
| Panzer, S | 1 |
| Lechner, K | 1 |
| Reale, LD | 1 |
| Besa, EC | 1 |
| Boruchov, DM | 1 |
| Gururangan, S | 1 |
| Driscoll, MC | 1 |
| Bussel, JB | 1 |
| Fujita, H | 1 |
| Togami, K | 1 |
| Mori, M | 1 |
| Hashimoto, H | 1 |
| Nagai, K | 1 |
| Nagai, Y | 1 |
| Tabata, S | 1 |
| Kurata, M | 1 |
| Mastusita, A | 1 |
| Maeda, A | 1 |
| Takahashi, T | 1 |
| Sáenz Abad, D | 1 |
| Ruiz-Ruiz, FJ | 1 |
| Monón Ballarín, S | 1 |
| Mozota Duarte, J | 1 |
| Marquina Barcos, A | 1 |
| Fukuda, M | 1 |
| Horibe, K | 1 |
| Miyajima, Y | 1 |
| Matsumoto, K | 1 |
| Kozaki, T | 1 |
| Komiyama, A | 1 |
| Yoshimura, T | 1 |
| Tamai, Y | 1 |
| Takami, H | 1 |
| Kariya, K | 1 |
| Nakahata, R | 1 |
| Tsushima, K | 1 |
| Munakata, A | 1 |
| Kawamura, S | 1 |
| Ohmine, K | 1 |
| Izumi, T | 1 |
| Muroi, K | 1 |
| Shimizu, R | 1 |
| Imagawa, S | 1 |
| Komatsu, N | 1 |
| Sasaki, R | 1 |
| Hatake, K | 1 |
| Miura, Y | 1 |
| Ozawa, K | 1 |
| Agarwal, V | 1 |
| Pal, S | 1 |
| Agarwal, A | 1 |
| Gupta, RK | 1 |
| Mishra, R | 1 |
| Balduini, CL | 1 |
| Bertolino, G | 1 |
| Noris, P | 1 |
| Piovella, F | 1 |
| Sinigaglia, F | 1 |
| Bellotti, V | 1 |
| Samaden, A | 1 |
| Torti, M | 1 |
| Mazzini, G | 1 |
| Yasunaga, K | 1 |
| Kokawa, T | 1 |
| Fujitake, H | 1 |
| Nomura, S | 1 |
| Kageyama, T | 1 |
| Ohyabu, H | 1 |
| Tatsumi, N | 1 |
| Im, T | 1 |
| Park, K | 1 |
| Kawagoe, H | 1 |
| Sousa, FC | 1 |
| Pinto Medeiros, J | 1 |
| Marques, R | 1 |
| Marques-Neves, C | 1 |
| Matsubara, K | 1 |
| Nigami, H | 1 |
| Harigaya, H | 1 |
| Tanaka, T | 1 |
| Yura, K | 1 |
| Nozaki, H | 1 |
| Iwata, A | 1 |
| Fukaya, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033] | 120 participants (Anticipated) | Interventional | 2022-08-15 | Enrolling by invitation | |||
| "French National Cohort of Patients With Pediatric-onset of Autoimmune Cytopenia (OBS'CEREVANCE Cohort)"[NCT05937828] | 3,500 participants (Anticipated) | Observational [Patient Registry] | 2010-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for azathioprine and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Relapse of Evans syndrome following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine: case report and literature review.
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Bilirubin; BNT162 Vaccine; Chronic Disease; COVID-19; C | 2023 |
Update οn the diagnosis and management of systemic lupus erythematosus.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc | 2021 |
Immune thrombocytopenic purpura associated with Crohn's disease with complete response to infliximab.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Azathioprine; Benzoates; Crohn Disease; Humans; Hydra | 2019 |
Refractory idiopathic immune thrombocytopenic purpura in children: current and future treatment options.
Topics: Adult; Antibodies, Monoclonal; Antineoplastic Agents; Azathioprine; Child; Child, Preschool; Cycloph | 2003 |
Rituximab in autoimmune pancytopenia: a case report and review of literature.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived | 2007 |
[Successful treatment with azathioprine for autoimmune thrombocytopenia developing after autologous peripheral blood stem cell transplantation].
Topics: Aged; Azathioprine; Humans; Immunosuppressive Agents; Male; Peripheral Blood Stem Cell Transplantati | 2007 |
3 trials available for azathioprine and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura.
Topics: Azathioprine; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppre | 2010 |
Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Child; Child, Pr | 2007 |
[Low-dose prednisolone therapy for idiopathic thrombocytopenic purpura].
Topics: Anti-Inflammatory Agents; Azathioprine; Combined Modality Therapy; Humans; Immunosuppressive Agents; | 2000 |
34 other studies available for azathioprine and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur | 2023 |
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur | 2023 |
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur | 2023 |
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur | 2023 |
Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study.
Topics: Antibodies, Antinuclear; Azathioprine; Humans; Immunosuppressive Agents; Prednisone; Purpura, Thromb | 2023 |
Immune thrombocytopenic purpura associated with inactive ulcerative colitis in chronic treatment with adalimumab.
Topics: Adalimumab; Anti-Inflammatory Agents; Azathioprine; Blood Transfusion; Colitis, Ulcerative; Female; | 2020 |
Combination Therapy of Azathioprine+ Dapsone as Effective Second Line Agents for the Treatment of Chronic Immune Thrombocytopenic Purpura.
Topics: Anti-Infective Agents; Azathioprine; Combined Modality Therapy; Dapsone; Humans; Immunosuppressive A | 2020 |
Multidrug Therapy for Refractory Immune Thrombocytopenia in Pregnancy.
Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Pregnancy; | 2020 |
NUDT15 polymorphism explains serious toxicity to azathioprine in Indian patients with chronic immune thrombocytopenia and autoimmune hemolytic anemia: a case series.
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Genotype; Humans; Leukopenia; Methyltransferases; Purpu | 2020 |
Prospective Evaluation of the First Option, Second-Line Therapy in Childhood Chronic Immune Thrombocytopenia: Splenectomy or Immunomodulation.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chronic Disease; Female; Humans; Hydroxychloroqui | 2021 |
Efficacy and tolerability of old and new drugs used in the treatment of immune thrombocytopenia: Results from a long-term observation in clinical practice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Benzoates; Child; Child, Preschool; Combin | 2018 |
Idiopathic Thrombocytopenic Purpura Responsive to Surgery for Crohn's Disease.
Topics: Adult; Azathioprine; Crohn Disease; Humans; Immunosuppressive Agents; Male; Prognosis; Purpura, Thro | 2019 |
Immune thrombocytopenia: Effectiveness of frontline steroids and comparison of azathioprine, splenectomy, and rituximab as second-line treatment.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Biomarkers; Combined Modality Therapy; Female; Humans; | 2018 |
A de novo monoallelic CTLA-4 deletion causing pediatric onset CVID with recurrent autoimmune cytopenias and severe enteropathy.
Topics: Adalimumab; Adolescent; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Autoimmune Diseases | 2018 |
A woman with recurrent anaemia and the Malawian health system.
Topics: Anemia, Hemolytic; Antibodies, Antinuclear; Azathioprine; Clinical Laboratory Services; Coombs Test; | 2013 |
Late-Onset Immune Thrombocytopenic Purpura After Withdrawal of Interferon Treatment for Chronic Hepatitis C Infection: A Case Report.
Topics: Age of Onset; Antiviral Agents; Azathioprine; Glucocorticoids; Hepatitis C, Chronic; Humans; Immunos | 2015 |
[A clinical study of 103 idiopathic thrombocytopenic purpura].
Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Azathioprine; China; Cyclophosphamide; Cyc | 2008 |
Therapeutic implications of T-cell clonopathy of unknown significance in chronic immune thrombocytopenic purpura.
Topics: Adult; Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Purpura, Thr | 2009 |
Chronic urticaria caused by folic acid.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Drug Hypersensitivity; Female; Folic Acid; Humans | 2009 |
Immune thrombocytopaenia in adults: a single-centre retrospective review of patients presenting over 7 years.
Topics: Adult; Antibodies, Antinuclear; Antineoplastic Agents, Phytogenic; Azathioprine; Biopsy, Fine-Needle | 2010 |
Should medical treatment options be exhausted before splenectomy is performed in adult ITP patients? A debate.
Topics: Adrenal Cortex Hormones; Azathioprine; Danazol; Humans; Purpura, Thrombocytopenic, Idiopathic; Recep | 2010 |
Rituximab-induced interstitial lung disease in a patient with immune thrombocytopenia purpura.
Topics: Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Combined Modality Therapy; | 2012 |
Hyperprolactinemia caused by azathioprine.
Topics: Adult; Azathioprine; Female; Hepatitis, Autoimmune; Humans; Hyperprolactinemia; Immunosuppressive Ag | 2003 |
A case of idiopathic thrombocytopenia and autoimmune hemolytic anemia treated with thymic irradiation and by administration of imuran and actinomycin-C.
Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Azathioprine; Dactinomycin; H | 1963 |
Spontaneous retroperitoneal bleeding in a patient with Evans syndrome.
Topics: Adult; Anemia, Hemolytic; Angiography; Anti-Inflammatory Agents; Antimetabolites; Azathioprine; Fema | 2004 |
Sustained remission of CIDP associated with Evans syndrome.
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclon | 2004 |
[Idiopathic thrombocytopenic purpura. A retrospective evaluation of 68 patients].
Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Azathioprine; Cyclophospha | 2004 |
Rituximab chimeric anti-CD20 monoclonal antibody treatment for adult refractory idiopathic thrombocytopenic purpura.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-D | 2005 |
Late spontaneous remissions in severe adult autoimmune thrombocytopenia.
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cohort Studies; Cyclosporine; Female; Humans; Im | 2007 |
[Pneumonitis associated to methotrexate].
Topics: Adrenal Cortex Hormones; Azathioprine; Diagnosis, Differential; Female; Humans; Immunosuppressive Ag | 2008 |
[Chronic myelomonocytic leukemia developed 9 years after the diagnosis of idiopathic thrombocytopenic purpura in a child].
Topics: Adolescent; Azathioprine; Combined Modality Therapy; Female; Humans; Leukemia, Myelomonocytic, Chron | 1994 |
[Rapidly progressive irradiated cervical cancer that metastasized to the liver during therapy for idiopathic thrombocytopenic purpura].
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Disease Progression; Female; Humans; Immunosuppressiv | 1999 |
Thrombocytopenia as the presenting manifestation of sarcoidosis.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Purpura, Thr | 2002 |
Defect of platelet aggregation and adhesion induced by autoantibodies against platelet glycoprotein IIIa.
Topics: Adult; Autoantibodies; Azathioprine; Blood Platelet Disorders; Female; Humans; Platelet Adhesiveness | 1992 |
[Effects of maintenance treatment after high-dose intravenous gamma-globulin for idiopathic thrombocytopenic purpura].
Topics: Adolescent; Adult; Aged; Azathioprine; Child; Combined Modality Therapy; Female; gamma-Globulins; Hu | 1991 |
Spontaneous retrobulbar haemorrhage in idiopathic thrombocytopenic purpura.
Topics: Adrenal Cortex Hormones; Aged, 80 and over; Humans; Intraocular Pressure; Male; Mercaptopurine; Purp | 2017 |
[Combination therapy with low-dose cyclosporin A, azathiopurine, and prednisolone for a child with refractory chronic idiopathic thrombocytopenic purpura].
Topics: Child, Preschool; Chronic Disease; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combina | 2007 |