azathioprine has been researched along with Pulmonary Sarcoidosis in 15 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sarcoidosis is a systemic inflammatory disease, characterised by granuloma formation upon an unknown trigger in genetically predisposed individuals." | 1.72 | Sarcoidosis - a multisystem disease. ( Böni, C; Brutsche, M; Daccord, C; Distler, O; Elsener, D; Franzen, DP; Funke-Chambour, M; Gruner, C; Hayward-Könnecke, H; Hostettler, KE; Kolios, AGA; Kündig, T; Nilsson, J; Ribi, C; Seebach, JD; Seeger, H; Vrugt, B, 2022) |
| "Steroids remain the first-choice therapeutic in sarcoidosis; however, long-term use is associated with toxicity." | 1.39 | Methotrexate vs azathioprine in second-line therapy of sarcoidosis. ( Deneer, VHM; Grutters, JC; Thomeer, M; van Moorsel, CHM; Veltkamp, M; Vorselaars, ADM; Vorselaars, VMM; Wuyts, WA; Zanen, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Franzen, DP | 1 |
| Brutsche, M | 1 |
| Nilsson, J | 1 |
| Böni, C | 1 |
| Daccord, C | 1 |
| Distler, O | 1 |
| Elsener, D | 1 |
| Funke-Chambour, M | 1 |
| Gruner, C | 1 |
| Hayward-Könnecke, H | 1 |
| Hostettler, KE | 1 |
| Kündig, T | 1 |
| Ribi, C | 1 |
| Seebach, JD | 1 |
| Seeger, H | 1 |
| Vrugt, B | 1 |
| Kolios, AGA | 1 |
| Lee, HN | 1 |
| Kim, JI | 1 |
| Won, K | 1 |
| Song, R | 1 |
| Vorselaars, ADM | 1 |
| Wuyts, WA | 1 |
| Vorselaars, VMM | 1 |
| Zanen, P | 1 |
| Deneer, VHM | 1 |
| Veltkamp, M | 1 |
| Thomeer, M | 1 |
| van Moorsel, CHM | 1 |
| Grutters, JC | 1 |
| Kotze, PG | 1 |
| de Barcelos, IF | 1 |
| da Silva Kotze, LM | 1 |
| Korsten, P | 1 |
| Mirsaeidi, M | 1 |
| Sweiss, NJ | 2 |
| Franzen, D | 1 |
| Mathys, C | 1 |
| Vesper, J | 1 |
| Malzkorn, B | 1 |
| Bohlen, H | 1 |
| Seitz, RJ | 1 |
| Bolat, S | 1 |
| Berding, G | 1 |
| Dengler, R | 1 |
| Stangel, M | 1 |
| Trebst, C | 1 |
| Skowasch, D | 1 |
| Pabst, S | 1 |
| Wilhelm, K | 1 |
| Grohé, C | 1 |
| Baughman, RP | 3 |
| Nunes, H | 1 |
| Lower, EE | 2 |
| Jindal, SK | 1 |
| Kirsten, D | 1 |
| Lewis, SJ | 1 |
| Ainslie, GM | 1 |
| Bateman, ED | 1 |
| Müller-Quernheim, J | 1 |
| Kienast, K | 1 |
| Held, M | 1 |
| Pfeifer, S | 1 |
| Costabel, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Endobronchial Mucosal Biopsy in Patients With Suspected Pulmonary Sarcoidosis[NCT04904939] | 20 participants (Actual) | Interventional | 2020-05-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for azathioprine and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Nonsteroidal therapy of sarcoidosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biological Products; Humans; Immunosuppressiv | 2013 |
Established and experimental medical therapy of pulmonary sarcoidosis.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Clinical Trials | 2013 |
Therapeutic options for sarcoidosis: new and old.
Topics: Adjuvants, Immunologic; Anti-Bacterial Agents; Azathioprine; Disease Progression; Glucocorticoids; H | 2002 |
Practical issues and challenges in the diagnosis and treatment of pulmonary sarcoidosis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Azathioprine; Cyclophosphamide; Humans; Immunosup | 2007 |
1 trial available for azathioprine and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Treatment of chronic sarcoidosis with an azathioprine/prednisolone regimen.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Bronchoalveolar Lavage Fluid; Drug Therapy, Combinati | 1999 |
10 other studies available for azathioprine and Pulmonary Sarcoidosis
| Article | Year |
|---|---|
Sarcoidosis - a multisystem disease.
Topics: Azathioprine; Humans; Immunosuppressive Agents; Quality of Life; Sarcoidosis; Sarcoidosis, Pulmonary | 2022 |
Atypical CT findings of pulmonary sarcoidosis: A case report.
Topics: Azathioprine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Lymphadenopathy; Middle Age | 2018 |
Methotrexate vs azathioprine in second-line therapy of sarcoidosis.
Topics: Azathioprine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Forced Expiratory Volume; | 2013 |
Sarcoidosis during therapy with adalimumab in a Crohn's disease patient: a paradoxical effect.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Biopsy, Needle; Colectomy; Crohn | 2013 |
[Progressive multifocal leukoencephalopathy following azathioprine and steroid treatment of pulmonary sarcoid disease].
Topics: Azathioprine; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multifocal; Male; M | 2015 |
Fluorodeoxyglucose positron emission tomography (FDG-PET) is useful in the diagnosis of neurosarcoidosis.
Topics: Anti-Inflammatory Agents; Azathioprine; Diagnosis, Differential; Encephalitis; Fluorodeoxyglucose F1 | 2009 |
[Diabetes insipidus due to neurosarcoidosis].
Topics: Adult; Anti-Inflammatory Agents; Antidiuretic Agents; Azathioprine; Biopsy; Central Nervous System D | 2011 |
[Sarcoidosis in Germany. Analysis of a questionnaire survey in 1992 of patients of the German Sarcoidosis Group].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Cortisone; Diagnosis, Differential; | 1995 |
Efficacy of azathioprine as second-line treatment in pulmonary sarcoidosis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Dose-Response Relationship, Drug; Female; Humans | 1999 |
New treatment for sarcoidosis: where's the proof?
Topics: Anti-Inflammatory Agents; Azathioprine; Clinical Trials as Topic; Glucocorticoids; Humans; Immunosup | 1999 |