azathioprine has been researched along with Primary Ovarian Insufficiency in 3 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Primary Ovarian Insufficiency: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To present a case of fertility restored by azathioprine treatment in a woman with autoimmune premature ovarian failure, Addison's disease, and ulcerative colitis, and to study the genetic background of the three autoimmune diseases." | 7.77 | Pregnancy after azathioprine therapy for ulcerative colitis in a woman with autoimmune premature ovarian failure and Addison's disease: HLA haplotype characterization. ( Cannavò, S; Ferraù, F; Gangemi, S; Trimarchi, F; Vita, G, 2011) |
| "To present a case of fertility restored by azathioprine treatment in a woman with autoimmune premature ovarian failure, Addison's disease, and ulcerative colitis, and to study the genetic background of the three autoimmune diseases." | 3.77 | Pregnancy after azathioprine therapy for ulcerative colitis in a woman with autoimmune premature ovarian failure and Addison's disease: HLA haplotype characterization. ( Cannavò, S; Ferraù, F; Gangemi, S; Trimarchi, F; Vita, G, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tuin, J | 1 |
| Sanders, JS | 1 |
| van Beek, AP | 1 |
| Hoek, A | 1 |
| Stegeman, CA | 1 |
| Ferraù, F | 1 |
| Gangemi, S | 1 |
| Vita, G | 1 |
| Trimarchi, F | 1 |
| Cannavò, S | 1 |
| McDermott, EM | 1 |
| Powell, RJ | 1 |
3 other studies available for azathioprine and Primary Ovarian Insufficiency
| Article | Year |
|---|---|
Brief Report: Menopause and Primary Ovarian Insufficiency in Women Treated for Antineutrophil Cytoplasmic Antibody-Associated Vasculitides.
Topics: Adult; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Azathioprine; Case-Control Studie | 2016 |
Pregnancy after azathioprine therapy for ulcerative colitis in a woman with autoimmune premature ovarian failure and Addison's disease: HLA haplotype characterization.
Topics: Addison Disease; Adult; Autoimmunity; Azathioprine; Colitis, Ulcerative; Female; Fertility; Haplotyp | 2011 |
Incidence of ovarian failure in systemic lupus erythematosus after treatment with pulse cyclophosphamide.
Topics: Adolescent; Adult; Age Factors; Azathioprine; Cohort Studies; Cyclophosphamide; Drug Administration | 1996 |