Page last updated: 2024-10-23

azathioprine and Primary Myelofibrosis

azathioprine has been researched along with Primary Myelofibrosis in 9 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Primary Myelofibrosis: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.

Research Excerpts

ExcerptRelevanceReference
"Primary myelofibrosis was diagnosed because of bone marrow fibrosis and extramedullary hematopoiesis of the spleen."5.29[Hematological remission of primary myelofibrosis with antiphospholipid antibody following treatment of azathioprine]. ( Kawamura, Y; Niki, T, 1995)
"Primary myelofibrosis was diagnosed because of bone marrow fibrosis and extramedullary hematopoiesis of the spleen."1.29[Hematological remission of primary myelofibrosis with antiphospholipid antibody following treatment of azathioprine]. ( Kawamura, Y; Niki, T, 1995)
"A female patient showed signs of osteomyelofibrosis after being treated for 70 months."1.26[Progressive systemic sclerosis - long-term treatment with azathioprin (author's transl)]. ( Jäckle, B; Maas, D; Raif, W; Schramm, A; Schubothe, H, 1979)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Narazaki, T1
Shiratsuchi, M1
Tsuda, M1
Tsukamoto, Y1
Muta, H1
Masuda, T1
Kimura, D1
Takamatsu, A1
Nakanishi, R1
Oki, E1
Fujiwara, M1
Oda, Y1
Nakashima, Y1
Ogawa, Y1
Ito, A1
Umeda, M1
Koike, T1
Naruse, S1
Fujita, N1
Domysławska, I1
Ciołkiewicz, M1
Kowal-Bielecka, O1
Lewszuk, A1
Klimiuk, PA1
Sierakowski, S1
Niki, T1
Kawamura, Y1
Mey, U1
Franke, A1
Fuchs, R1
Maas, D1
Schramm, A1
Jäckle, B1
Raif, W1
Schubothe, H1
Foley-Nolan, D1
Martin, MF1
Rowbotham, D1
McVerry, A1
Gooi, HC1
Engelmann, C1
Schulz, K1
Nowotny, P1
Konrad, H1
Hauswaldt, C1
Hunseein, W1
Kaboth, U1
Lattermann, W1

Other Studies

9 other studies available for azathioprine and Primary Myelofibrosis

ArticleYear
Intestinal Behçet's Disease with Primary Myelofibrosis Involving Trisomy 8.
    Acta haematologica, 2019, Volume: 142, Issue:4

    Topics: Azathioprine; Behcet Syndrome; Chromosomes, Human, Pair 8; Female; Humans; Infliximab; Intestinal Pe

2019
[A case of dermatomyositis associated with chronic idiopathic myelofibrosis].
    Rinsho shinkeigaku = Clinical neurology, 2006, Volume: 46, Issue:3

    Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Chronic Disease; Dermatomyositis; Drug Therapy, Combin

2006
[Coexistence of scleroderma-like syndrome and idiopathic myelofibrosis in a 54-year-old female patient: case report].
    Polskie Archiwum Medycyny Wewnetrznej, 2007, Volume: 117, Issue:8

    Topics: Antineoplastic Agents; Azathioprine; Female; Glucocorticoids; Humans; Hydroxyurea; Immunosuppressive

2007
[Hematological remission of primary myelofibrosis with antiphospholipid antibody following treatment of azathioprine].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:2

    Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Azathioprine; Female; Humans; Middle Aged;

1995
[Acute mature myelocytic leukemia as a form of the myeloproliferative syndrome].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1979, Sep-15, Volume: 34, Issue:18

    Topics: Acute Disease; Adult; Azathioprine; Bone Marrow Examination; Fetal Hemoglobin; Hematopoietic Stem Ce

1979
[Progressive systemic sclerosis - long-term treatment with azathioprin (author's transl)].
    Immunitat und Infektion, 1979, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Azathioprine; Female; Humans; Male; Middle Aged; P

1979
Systemic lupus erythematosus presenting with myelofibrosis.
    The Journal of rheumatology, 1992, Volume: 19, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Biopsy; Bone Marrow; Diagnosis, Differential; Dose-Res

1992
[Indications for cytostatic treatment of patients with osteomyelosclerosis of osteomyelofibrosis].
    Das Deutsche Gesundheitswesen, 1972, Dec-14, Volume: 27, Issue:50

    Topics: Adult; Aged; Antineoplastic Agents; Azathioprine; Busulfan; Female; Humans; Male; Mannitol; Mercapto

1972
[Animal experimental production of bone marrow fibroses using repeated injections of foreign protein and their medicamentous influencing through azathioprine and prednisolone].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1969, Volume: 75

    Topics: Animals; Azathioprine; Ovalbumin; Prednisolone; Primary Myelofibrosis; Rabbits

1969