azathioprine has been researched along with Preterm Birth in 14 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to describe prescription patterns for azathioprine and corticosteroids for pregnant women with inflammatory bowel diseases (IBD) before, during, and after pregnancy and to describe pregnancy outcomes." | 7.83 | Use of azathioprine and corticosteroids during pregnancy and birth outcome in women diagnosed with inflammatory bowel disease. ( Garne, E; Hansen, AV; Plauborg, AV, 2016) |
| "The objective of this study was to evaluate the risk of adverse fetal outcome in systemic lupus erythematosus (SLE) women exposed to azathioprine during pregnancy." | 7.81 | Azathioprine during pregnancy in systemic lupus erythematosus patients is not associated with poor fetal outcome. ( Ángeles, U; Jara, LJ; Morales, S; Saavedra, MÁ; Sánchez, A, 2015) |
| "The aim of this study was to describe prescription patterns for azathioprine and corticosteroids for pregnant women with inflammatory bowel diseases (IBD) before, during, and after pregnancy and to describe pregnancy outcomes." | 3.83 | Use of azathioprine and corticosteroids during pregnancy and birth outcome in women diagnosed with inflammatory bowel disease. ( Garne, E; Hansen, AV; Plauborg, AV, 2016) |
| "The objective of this study was to evaluate the risk of adverse fetal outcome in systemic lupus erythematosus (SLE) women exposed to azathioprine during pregnancy." | 3.81 | Azathioprine during pregnancy in systemic lupus erythematosus patients is not associated with poor fetal outcome. ( Ángeles, U; Jara, LJ; Morales, S; Saavedra, MÁ; Sánchez, A, 2015) |
| " Before conception and in early pregnancy, azathioprine and prednisone were administered in 48." | 3.75 | Follow-up of pregnant women with autoimmune hepatitis: the disease behavior along with maternal and fetal outcomes. ( Abrantes-Lemos, CP; Cançado, EL; Carrilho, FJ; Terrabuio, DR, 2009) |
| "Pregnancy in a woman with systemic lupus erythematosus (SLE) can be complicated by both lupus activity and pregnancy mishaps." | 2.44 | Lupus activity in pregnancy. ( Clowse, ME, 2007) |
| "Our primary aim was to assess infection rate and our secondary aims were to assess adverse reactions to vaccinations, growth, autoimmune diseases and malignancies." | 1.62 | Health outcomes of 1000 children born to mothers with inflammatory bowel disease in their first 5 years of life. ( Beukers, R; Bodelier, A; de Boer, N; de Lima, A; Depla, ACTM; Dijkstra, G; Erler, N; Escher, JC; Gilissen, L; Hoentjen, F; Jansen, JM; Kanis, SL; Kuyvenhoven, J; Mahmmod, N; Mallant-Hent, RC; Modderman, S; Noruzi, A; Oldenburg, B; Oostenbrug, LE; Pierik, M; Romberg-Camps, M; Ter Borg, PCJ; Thijs, W; van der Meulen-de Jong, AE; van der Woude, CJ; van Dijk, ARM; West, R, 2021) |
| "The outcomes were congenital abnormalities (CAs), preterm birth and small for gestational age (SGA)." | 1.46 | Reassuring results on birth outcomes in children fathered by men treated with azathioprine/6-mercaptopurine within 3 months before conception: a nationwide cohort study. ( Friedman, S; Larsen, MD; Magnussen, B; Nørgård, BM, 2017) |
| "Preterm birth was seen in 26." | 1.37 | The effects of azathioprine on birth outcomes in women with inflammatory bowel disease (IBD). ( Eslick, GD; Murray, H; Shim, L; Simring, AA; Weltman, MD, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Reynolds, JA | 1 |
| Gayed, M | 1 |
| Khamashta, MA | 1 |
| Leone, F | 1 |
| Toescu, V | 1 |
| Bruce, IN | 1 |
| Giles, I | 1 |
| Teh, LS | 1 |
| McHugh, N | 1 |
| Akil, M | 1 |
| Edwards, CJ | 1 |
| Gordon, C | 1 |
| Zhang, Y | 1 |
| Li, D | 1 |
| Guo, H | 1 |
| Wang, W | 1 |
| Li, X | 1 |
| Shen, S | 1 |
| Hammad, I | 1 |
| Porter, TF | 1 |
| Chehab, G | 1 |
| Krüssel, J | 1 |
| Fehm, T | 1 |
| Fischer-Betz, R | 1 |
| Schneider, M | 1 |
| Germeyer, A | 1 |
| Suerdieck, MB | 1 |
| Kreuzer, V | 1 |
| Liebenthron, J | 1 |
| Saavedra, MÁ | 1 |
| Sánchez, A | 1 |
| Morales, S | 1 |
| Ángeles, U | 1 |
| Jara, LJ | 1 |
| Plauborg, AV | 1 |
| Hansen, AV | 1 |
| Garne, E | 1 |
| Nørgård, BM | 1 |
| Magnussen, B | 1 |
| Larsen, MD | 1 |
| Friedman, S | 1 |
| Terrabuio, DR | 1 |
| Abrantes-Lemos, CP | 1 |
| Carrilho, FJ | 1 |
| Cançado, EL | 1 |
| Shim, L | 1 |
| Eslick, GD | 1 |
| Simring, AA | 1 |
| Murray, H | 1 |
| Weltman, MD | 1 |
| Akbari, M | 1 |
| Shah, S | 1 |
| Velayos, FS | 1 |
| Mahadevan, U | 1 |
| Cheifetz, AS | 1 |
| Hutson, JR | 1 |
| Matlow, JN | 1 |
| Moretti, ME | 1 |
| Koren, G | 2 |
| Clowse, ME | 1 |
| Goldstein, LH | 1 |
| Dolinsky, G | 1 |
| Greenberg, R | 1 |
| Schaefer, C | 1 |
| Cohen-Kerem, R | 1 |
| Diav-Citrin, O | 1 |
| Malm, H | 1 |
| Reuvers-Lodewijks, ME | 1 |
| Rost van Tonningen-van Driel, MM | 1 |
| Arnon, J | 1 |
| Ornoy, A | 1 |
| Clementi, M | 1 |
| Di Gianantonio, E | 1 |
| Braunstein, R | 1 |
| Berkovitch, M | 1 |
| Kanis, SL | 1 |
| Modderman, S | 1 |
| Escher, JC | 1 |
| Erler, N | 1 |
| Beukers, R | 1 |
| de Boer, N | 1 |
| Bodelier, A | 1 |
| Depla, ACTM | 1 |
| Dijkstra, G | 1 |
| van Dijk, ARM | 1 |
| Gilissen, L | 1 |
| Hoentjen, F | 1 |
| Jansen, JM | 1 |
| Kuyvenhoven, J | 1 |
| Mahmmod, N | 1 |
| Mallant-Hent, RC | 1 |
| van der Meulen-de Jong, AE | 1 |
| Noruzi, A | 1 |
| Oldenburg, B | 1 |
| Oostenbrug, LE | 1 |
| Ter Borg, PCJ | 1 |
| Pierik, M | 1 |
| Romberg-Camps, M | 1 |
| Thijs, W | 1 |
| West, R | 1 |
| de Lima, A | 1 |
| van der Woude, CJ | 1 |
5 reviews available for azathioprine and Preterm Birth
| Article | Year |
|---|---|
Association between Thiopurines Use and Pregnancy Outcomes in Female Patients with Inflammatory Bowel Disease: A Meta-Analysis.
Topics: Azathioprine; Colitis; Female; Humans; Infant, Newborn; Inflammatory Bowel Diseases; Pregnancy; Preg | 2021 |
An Update on Biologic Agents During Pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humani | 2020 |
Systematic review and meta-analysis on the effects of thiopurines on birth outcomes from female and male patients with inflammatory bowel disease.
Topics: Azathioprine; Congenital Abnormalities; Female; Humans; Immunosuppressive Agents; Infant, Low Birth | 2013 |
The fetal safety of thiopurines for the treatment of inflammatory bowel disease in pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Azathioprine; Birth Weight; Case-Contro | 2013 |
Lupus activity in pregnancy.
Topics: Adult; Animals; Azathioprine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Lupus Eryth | 2007 |
1 trial available for azathioprine and Preterm Birth
| Article | Year |
|---|---|
Pregnancy outcome of women exposed to azathioprine during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Case-Control Studies; Female; Gestational Age; H | 2007 |
8 other studies available for azathioprine and Preterm Birth
| Article | Year |
|---|---|
Outcomes of children born to mothers with systemic lupus erythematosus exposed to hydroxychloroquine or azathioprine.
Topics: Adolescent; Antirheumatic Agents; Azathioprine; Child; Female; Humans; Hydroxychloroquine; Lupus Ery | 2023 |
Successful conception in a 34-year-old lupus patient following spontaneous pregnancy after autotransplantation of cryopreserved ovarian tissue.
Topics: Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Cryopreservation; Cyclophosphamide; Female; | 2019 |
Azathioprine during pregnancy in systemic lupus erythematosus patients is not associated with poor fetal outcome.
Topics: Abortion, Spontaneous; Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Infant, Newbor | 2015 |
Use of azathioprine and corticosteroids during pregnancy and birth outcome in women diagnosed with inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Denmark; Female; Humans; Infant, Low Birth Weight; Inf | 2016 |
Reassuring results on birth outcomes in children fathered by men treated with azathioprine/6-mercaptopurine within 3 months before conception: a nationwide cohort study.
Topics: Adult; Azathioprine; Case-Control Studies; Cohort Studies; Congenital Abnormalities; Denmark; Female | 2017 |
Follow-up of pregnant women with autoimmune hepatitis: the disease behavior along with maternal and fetal outcomes.
Topics: Abortion, Spontaneous; Adolescent; Adult; Azathioprine; Congenital Abnormalities; Female; Hepatitis, | 2009 |
The effects of azathioprine on birth outcomes in women with inflammatory bowel disease (IBD).
Topics: Adult; Azathioprine; Female; Gestational Age; Humans; Immunosuppressive Agents; Infant, Low Birth We | 2011 |
Health outcomes of 1000 children born to mothers with inflammatory bowel disease in their first 5 years of life.
Topics: Adalimumab; Adult; Anti-Bacterial Agents; Autoimmune Diseases; Cesarean Section; Child Development; | 2021 |