Page last updated: 2024-10-23

azathioprine and Precancerous Conditions

azathioprine has been researched along with Precancerous Conditions in 11 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chanda, JJ1
Callen, JP1
Nyberg, G1
Eriksson, O1
Westberg, NG1
Benfield, JR1
Shors, EC1
Okita, M1
Matsumura, K1
Cohen, AH1
Zóltowska, A1
Taylor, AE1
Shuster, S1
Shuttleworth, D1
Marks, R1
Griffin, PJ1
Salaman, JR1
Krickeberg, H1
Marshall, V1
Gupta, PK1
Pinn, VM1
Taft, PD1
Krüger, GR1
Schuppli, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Clinical Trial Evaluating the Immunological Response of Vaccination Against Infection by Human Papillomavirus (HPV) 6, 11, 16, 18 in Girls Receiving Immunosuppressive Therapy.[NCT01687192]Phase 237 participants (Anticipated)Interventional2012-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for azathioprine and Precancerous Conditions

ArticleYear
Necrotizing vasculitis (angiitis) with granulomatosis.
    International journal of dermatology, 1984, Volume: 23, Issue:2

    Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Granuloma, Lethal Midline; Gr

1984
Increased incidence of cervical atypia in women with systemic lupus erythematosus treated with chemotherapy.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:5

    Topics: Adult; Aged; Azathioprine; Cervix Uteri; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged;

1981
Effects of localized chemical carcinogenesis and immunosuppression upon bronchial preneoplasia in the dog.
    The Journal of thoracic and cardiovascular surgery, 1977, Volume: 74, Issue:5

    Topics: Animals; Azathioprine; Benzopyrenes; Bronchial Neoplasms; Carcinogens; Disease Models, Animal; Dogs;

1977
Lymphoreticular tissue lesions in mice after immunization with typhoid fever vaccine and immunosuppression with azathioprine.
    Beitrage zur Pathologie, 1975, Volume: 156, Issue:3

    Topics: Animals; Atrophy; Azathioprine; Female; Hyperplasia; Immunization Schedule; Immunosuppression Therap

1975
Skin cancer after renal transplantation: the causal role of azathioprine.
    Acta dermato-venereologica, 1992, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Aged; Azathioprine; Cocarcinogenesis; Female; Humans; Immunosuppression Therapy;

1992
Epidermal dysplasia and cyclosporine therapy in renal transplant patients: a comparison with azathioprine.
    The British journal of dermatology, 1989, Volume: 120, Issue:4

    Topics: Adolescent; Adult; Aged; Azathioprine; Cyclosporins; Drug Eruptions; Humans; Kidney Transplantation;

1989
[Development of multiple precancerous conditions and malignant skin tumors in immunosuppressive therapy].
    Zeitschrift fur Hautkrankheiten, 1988, Sep-15, Volume: 63, Issue:9

    Topics: Azathioprine; Fluocortolone; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Trans

1988
Premalignant and malignant skin tumours in immunosuppressed patients.
    Transplantation, 1974, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Azathioprine; Cadaver; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyc

1974
Cervical dysplasia associated with azathioprine (Imuran) therapy.
    Acta cytologica, 1969, Volume: 13, Issue:7

    Topics: Adult; Azathioprine; Cervix Uteri; Cytodiagnosis; Female; Humans; Kidney Failure, Chronic; Kidney Tr

1969
Host response during the latent period and the growth of an immunologically induced mouse lymphoma.
    Beitrage zur Pathologie, 1972, Volume: 146, Issue:2

    Topics: Animals; Antibody Formation; Antigens, Neoplasm; Azathioprine; Cross Reactions; Female; Freund's Adj

1972
[Practical use of immunosuppressive and cytostatic drugs in dermatological diseases].
    Minerva medica, 1970, Jul-11, Volume: 61, Issue:55

    Topics: Antineoplastic Agents; Azathioprine; Condylomata Acuminata; Fluorouracil; Humans; Immunosuppressive

1970