Page last updated: 2024-10-23

azathioprine and Pre-Eclampsia

azathioprine has been researched along with Pre-Eclampsia in 12 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

Research Excerpts

ExcerptRelevanceReference
" The last drug was substituted with azathioprine in prevision of pregnancy."4.91Pregnancies in women receiving renal transplant for lupus nephritis: description of nine pregnancies and review of the literature. ( Campise, M; Giglio, E; Messa, P; Moroni, G; Trespidi, L, 2015)
"Adequate pregnancy care of women with systemic lupus erythematosus (SLE) rests on three pillars: a coordinated medical-obstetrical care, an agreed and well-defined management protocol and a good neonatal unit."2.47Lupus and pregnancy: integrating clues from the bench and bedside. ( Khamashta, MA; Ruiz-Irastorza, G, 2011)
"Pregnancy in a woman with systemic lupus erythematosus (SLE) can be complicated by both lupus activity and pregnancy mishaps."2.44Lupus activity in pregnancy. ( Clowse, ME, 2007)
"One patient developed Kaposi sarcoma of the cervix."2.40[Pregnancy after heart and heart-lung transplantation. Apropos of 10 cases and review of the literature]. ( Fernandez, H; Frydman, R; Troché, V; Ville, Y, 1997)
"Pregnancy hypertension was found in three pregnancies, one of which progressed to pre-eclampsia."1.91Pregnancy after kidney transplantation: Ibn Sina Rabat University hospital experience ( Azzouzi, A; Bayahia, R; Benamar, L; Bouattar, T; Driouch, L; Ouzeddoun, N, 2023)
"Pregnancy hypertension was found in three pregnancies, one of which progressed to pre-eclampsia."1.91Pregnancy after kidney transplantation: Ibn Sina Rabat University hospital experience ( Azzouzi, A; Bayahia, R; Benamar, L; Bouattar, T; Driouch, L; Ouzeddoun, N, 2023)
"Pregnancy is associated with specific immunological tolerance to fetal antigens suggesting that immunoregulatory processes during pregnancy can induce specific immunological unresponsiveness."1.29Specific immune tolerance during pregnancy after renal transplantation. ( Barenbrock, M; Fischer, T; Schobel, H, 1996)
"Then a sudden and rapidly worsening preeclampsia led to admission and delivery."1.28Pregnancy and postpartum after kidney transplantation and cyclosporin therapy--review of the literature adding a new case. ( Bung, P; Molitor, D, 1991)
"Most frequent are preeclampsia, premature labour, foetal maldevelopment and flare-ups of the underlying disease."1.28[Systemic lupus erythematosus and pregnancy. Clinical aspects, serology and management]. ( DuBois, A; Hillemanns, HG; Kerl, J; Quaas, L; Röther, E; Runge, HM, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Driouch, L2
Azzouzi, A2
Ouzeddoun, N2
Benamar, L2
Bayahia, R2
Bouattar, T2
Brännström, M1
Johannesson, L1
Bokström, H1
Kvarnström, N1
Mölne, J1
Dahm-Kähler, P1
Enskog, A1
Milenkovic, M1
Ekberg, J1
Diaz-Garcia, C1
Gäbel, M1
Hanafy, A1
Hagberg, H1
Olausson, M1
Nilsson, L1
Campise, M1
Giglio, E1
Trespidi, L1
Messa, P1
Moroni, G1
Ruiz-Irastorza, G1
Khamashta, MA1
Korkmaz, C1
Kabukcuoğlu, S1
Isiksoy, S1
Yalçin, AU1
Clowse, ME1
TambyRaja, RL1
Fischer, T1
Schobel, H1
Barenbrock, M1
Troché, V1
Ville, Y1
Frydman, R1
Fernandez, H1
Bung, P1
Molitor, D1
Runge, HM1
Röther, E1
Kerl, J1
DuBois, A1
Quaas, L1
Hillemanns, HG1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
First Clinical Live-Donor Uterus Transplantation Trial In Egypt[NCT03284073]11 participants (Anticipated)Interventional2021-09-01Not yet recruiting
Feasibility Study of Uterine Transplantation From Living Donors in Terms of Efficacy and Safety in Patients With Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH)[NCT03689842]20 participants (Anticipated)Interventional2017-12-14Recruiting
Prospective Case Series of Human Uterus Transplantation From Live Donor[NCT01844362]9 participants (Actual)Interventional2012-09-30Completed
Uterine Transplantation and Pregnancy Induction in Women Affected by Absolute Uterine Factor Infertility[NCT02656550]20 participants (Anticipated)Interventional2015-11-11Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for azathioprine and Pre-Eclampsia

ArticleYear
Pregnancies in women receiving renal transplant for lupus nephritis: description of nine pregnancies and review of the literature.
    Lupus, 2015, Volume: 24, Issue:11

    Topics: Abortion, Spontaneous; Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antihypertensive Ag

2015
Lupus and pregnancy: integrating clues from the bench and bedside.
    European journal of clinical investigation, 2011, Volume: 41, Issue:6

    Topics: Abortion, Spontaneous; Antibodies, Antiphospholipid; Anticoagulants; Aspirin; Azathioprine; Counseli

2011
Lupus activity in pregnancy.
    Rheumatic diseases clinics of North America, 2007, Volume: 33, Issue:2

    Topics: Adult; Animals; Azathioprine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Lupus Eryth

2007
[Pregnancy after heart and heart-lung transplantation. Apropos of 10 cases and review of the literature].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1997, Volume: 26, Issue:6

    Topics: Adrenal Cortex Hormones; Azathioprine; Birth Weight; Cardiomyopathy, Hypertrophic; Cesarean Section;

1997

Other Studies

8 other studies available for azathioprine and Pre-Eclampsia

ArticleYear
Pregnancy after kidney transplantation: Ibn Sina Rabat University hospital experience
    Nephrologie & therapeutique, 2023, 03-15, Volume: 19, Issue:1

    Topics: Azathioprine; Cesarean Section; Child; Child, Preschool; Creatinine; Female; Graft Rejection; Hospit

2023
Pregnancy after kidney transplantation: Ibn Sina Rabat University hospital experience
    Nephrologie & therapeutique, 2023, 04-26, Volume: 19, Issue:2

    Topics: Azathioprine; Cesarean Section; Child; Child, Preschool; Creatinine; Female; Graft Rejection; Hospit

2023
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Livebirth after uterus transplantation.
    Lancet (London, England), 2015, Feb-14, Volume: 385, Issue:9968

    Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa

2015
Renal involvement in primary antiphospholipid syndrome and its response to immunosuppressive therapy.
    Lupus, 2003, Volume: 12, Issue:10

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Azathioprine; Female; Glomeruloscler

2003
Fetal salvage in maternal systemic lupus erythematosus.
    Annals of the Academy of Medicine, Singapore, 1993, Volume: 22, Issue:4

    Topics: Abortion, Spontaneous; Adult; Azathioprine; Female; Fetal Death; Humans; Infant, Newborn; Kidney Fun

1993
Specific immune tolerance during pregnancy after renal transplantation.
    European journal of obstetrics, gynecology, and reproductive biology, 1996, Dec-27, Volume: 70, Issue:2

    Topics: Adult; Azathioprine; Female; Fetal Membranes, Premature Rupture; Graft Rejection; Humans; Immune Tol

1996
Pregnancy and postpartum after kidney transplantation and cyclosporin therapy--review of the literature adding a new case.
    Journal of perinatal medicine, 1991, Volume: 19, Issue:5

    Topics: Adult; Azathioprine; Cesarean Section; Cyclosporine; Female; Humans; Immunosuppression Therapy; Kidn

1991
[Systemic lupus erythematosus and pregnancy. Clinical aspects, serology and management].
    Geburtshilfe und Frauenheilkunde, 1990, Volume: 50, Issue:7

    Topics: Antibodies, Antinuclear; Azathioprine; Female; Fetal Death; Humans; Infant, Newborn; Lupus Erythemat

1990