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azathioprine and Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

azathioprine has been researched along with Polyradiculoneuropathy, Chronic Inflammatory Demyelinating in 29 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating: A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)

Research Excerpts

ExcerptRelevanceReference
"We sought randomised and quasi-randomised trials of all immunosuppressive agents such as azathioprine, cyclophosphamide, methotrexate, ciclosporin A, mycophenolate mofetil, and rituximab and all immunomodulatory agents such as interferon alfa and interferon beta in participants fulfilling standard diagnostic criteria for chronic inflammatory demyelinating polyradiculoneuropathy."4.86Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy. ( Hughes, RA; Mahdi-Rogers, M; Swan, AV; van Doorn, PA, 2010)
"We sought randomised and quasi-randomised trials of all immunosuppressive agents such as azathioprine, cyclophosphamide, methotrexate, cyclosporin A, mycophenolate mofetil, and rituximab and all immunomodulatory agents such as alpha interferon and beta interferon in participants fulfilling standard diagnostic criteria for chronic inflammatory demyelinating polyradiculoneuropathy."4.82Cytotoxic drugs and interferons for chronic inflammatory demyelinating polyradiculoneuropathy. ( Hughes, RA; Swan, AV; van Doorn, PA, 2003)
"We sought randomised and quasi-randomised trials of all immunosuppressive agents such as azathioprine, cyclophosphamide, methotrexate, cyclosporin A, mycophenolate mofetil, and rituximab and all immunomodulatory agents such as alpha interferon and beta interferon in participants fulfilling standard diagnostic criteria for chronic inflammatory demyelinating polyradiculoneuropathy."4.82Cytotoxic drugs and interferons for chronic inflammatory demyelinating polyradiculoneuropathy. ( Hughes, RA; Swan, AV; van Doorn, PA, 2004)
"Eighteen of them also had monoclonal gammopathy of undetermined significance (MGUS)."2.69Chronic inflammatory demyelinating polyradiculoneuropathy: long-term course and treatment of 60 patients. ( Ciano, C; Fallica, E; Mariotti, C; Pareyson, D; Sghirlanzoni, A; Solari, A, 2000)
"In addition, patients with typical CIDP were divided into two groups according to the first-line treatment modalities (group 1: IVIg only, group 2: IVIg + steroid)."1.91Pediatric-Onset Chronic Inflammatory Demyelinating Polyneuropathy: A Multicenter Study. ( Acar Arslan, E; Aksoy, A; Aksoy, E; Aliyeva, N; Ayanoğlu, M; Bektaş, Ö; Bodur, M; Canpolat, M; Çobanoğulları Direk, M; Gençpınar, P; Güleç, A; Gümüş, H; Gürkaş, E; Hız Kurul, S; Kanmaz, S; Keskin Yılmaz, S; Kızılırmak, AB; Kömür, M; Okuyaz, Ç; Olgaç Dündar, N; Öz Tuncer, G; Öztoprak, Ü; Öztürk, S; Per, H; Sarıkaya Uzan, G; Teber, S; Tekgül, H; Tosun, A; Ünalp, A; Ünay, B; Vural, A; Yıldırım, Ç; Yılmaz, Ü; Yiş, U; Yousefi, M; Yüksel, D, 2023)
"IR-CAP could well be 'axonal CIDP' in view of clinical similarity, but not proven as yet."1.56Chronic inflammatory axonal polyneuropathy. ( Alsharabati, M; King, P; Lu, L; Morgan, MB; Oh, SJ, 2020)
"Childhood chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare condition, and the optimal treatment strategy is not well established, especially in refractory cases."1.51Chronic inflammatory demyelinating polyneuropathy: Plasmapheresis or cyclosporine can be good treatment options in refractory cases. ( Chae, JH; Choi, J; Choi, SA; Hwang, H; Kim, H; Kim, KJ; Kim, SY; Kim, W; Lim, BC; Shim, YK, 2019)
"Sixty-three CIDP patients were identified."1.46Clinical Characteristics and Treatment Response of Chronic Inflammatory Demyelinating Polyradiculoneuropathy. ( Hanchaiphiboolkul, S; Suanprasert, N, 2017)
"Acute-onset CIDP resembles Guillain-Barre syndrome (GBS), a rapidly progressive disorder, and follows a chronic course."1.43Acute-onset chronic inflammatory demyelinating polyneuropathy in hantavirus and hepatitis B virus coinfection: A case report. ( Choi, EH; Lim, JY; Lim, YH, 2016)
"Azathioprine was started."1.42CIDP variants in diabetes: measuring treatment response with a small nerve fiber test. ( Névoret, ML; Vinik, AI, 2015)
"To describe 31 children presenting a CIDP; to compare patients with rapid-onset disease vs."1.42Childhood CIDP: Study of 31 patients and comparison between slow and rapid-onset groups. ( Boulay, C; Cabasson, S; Meunier, A; Pedespan, JM; Rouanet-Larriviere, MF; Tardieu, M, 2015)
"In conclusion, CIDP is a clinically heterogeneous disorder."1.34Chronic inflammatory demyelinating polyneuropathy: a 6-year retrospective clinical study of a hospital-based population. ( Anyfanti, C; Ioannou, M; Kaponi, A; Pandis, D; Rentzos, M; Vassilopoulos, D, 2007)
"We present 4 patients with CIDP who required respiratory assistance and mechanical ventilation."1.33Chronic inflammatory demyelinating polyneuropathy and respiratory failure. ( Henderson, RD; Sandroni, P; Wijdicks, EF, 2005)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (44.83)29.6817
2010's10 (34.48)24.3611
2020's6 (20.69)2.80

Authors

AuthorsStudies
Kim, S1
Lee, EK1
Sohn, E1
Sarıkaya Uzan, G1
Vural, A1
Yüksel, D1
Aksoy, E1
Öztoprak, Ü1
Canpolat, M1
Öztürk, S1
Yıldırım, Ç1
Güleç, A1
Per, H1
Gümüş, H1
Okuyaz, Ç1
Çobanoğulları Direk, M1
Kömür, M1
Ünalp, A1
Yılmaz, Ü1
Bektaş, Ö1
Teber, S1
Aliyeva, N1
Olgaç Dündar, N1
Gençpınar, P1
Gürkaş, E1
Keskin Yılmaz, S1
Kanmaz, S1
Tekgül, H1
Aksoy, A1
Öz Tuncer, G1
Acar Arslan, E1
Tosun, A1
Ayanoğlu, M1
Kızılırmak, AB1
Yousefi, M1
Bodur, M1
Ünay, B1
Hız Kurul, S1
Yiş, U1
Mehreen, S1
Iftikhar, S1
Muhammad, A1
Aatif Siddique, R1
Shahid, S1
Kim, W1
Shim, YK1
Choi, SA1
Kim, SY1
Kim, H1
Lim, BC1
Hwang, H1
Choi, J1
Kim, KJ1
Chae, JH1
Muley, SA1
Jacobsen, B1
Parry, G1
Usman, U1
Ortega, E1
Walk, D1
Allen, J1
Pasnoor, M1
Varon, M1
Dimachkie, MM1
George, IC1
Kvalsund, M1
Saylor, D1
Oh, SJ1
Lu, L1
Alsharabati, M1
Morgan, MB1
King, P1
Mahdi-Rogers, M3
Brassington, R1
Gunn, AA1
van Doorn, PA5
Hughes, RA6
Suanprasert, N1
Hanchaiphiboolkul, S1
Névoret, ML1
Vinik, AI1
Cabasson, S1
Tardieu, M1
Meunier, A1
Rouanet-Larriviere, MF1
Boulay, C1
Pedespan, JM1
Lim, JY1
Lim, YH1
Choi, EH1
Oaklander, AL1
Lunn, MP1
van Schaik, IN1
Frost, C1
Chalk, CH1
Otto, F1
Neuen-Jacob, E1
Arendt, G1
Stüve, O1
Hartung, HP1
Swan, AV3
Cocito, D1
Grimaldi, S1
Paolasso, I1
Falcone, Y1
Antonini, G1
Benedetti, L1
Briani, C1
Fazio, R1
Jann, S1
Matà, S1
Sabatelli, M1
Nobile-Orazio, E1
Pavesi, G1
Cattaneo, L1
Marbini, A1
Gemignani, F1
Mancia, D1
Haq, RU1
Pendlebury, WW1
Fries, TJ1
Tandan, R1
Knecht, H1
Baumberger, M1
Tobòn, A1
Steck, A1
França, MC1
de Castro, R1
de Oliveira, MF1
Garibaldi, SG1
Nucci, A1
de Souza Queiroz, L1
Kraemer, MH1
Henderson, RD1
Sandroni, P1
Wijdicks, EF1
Rentzos, M1
Anyfanti, C1
Kaponi, A1
Pandis, D1
Ioannou, M1
Vassilopoulos, D1
Rossignol, E1
D'Anjou, G1
Lapointe, N1
Haddad, E1
Vanasse, M1
Pedersen, K1
Pandolfo, M1
Mavroudakis, N1
Reményi, P1
Masszi, T1
Borbényi, Z1
Soós, J1
Siklós, L1
Engelhardt, JI1
Sghirlanzoni, A1
Solari, A1
Ciano, C1
Mariotti, C1
Fallica, E1
Pareyson, D1

Reviews

6 reviews available for azathioprine and Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

ArticleYear
Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy.
    The Cochrane database of systematic reviews, 2017, 05-08, Volume: 5

    Topics: Anti-Inflammatory Agents; Azathioprine; Humans; Immunoglobulins, Intravenous; Immunologic Factors; I

2017
Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy.
    The Cochrane database of systematic reviews, 2013, Jun-14, Issue:6

    Topics: Anti-Inflammatory Agents; Azathioprine; Humans; Immunologic Factors; Immunosuppressive Agents; Inter

2013
Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews.
    The Cochrane database of systematic reviews, 2017, 01-13, Volume: 1

    Topics: Adrenal Cortex Hormones; Azathioprine; Dexamethasone; Humans; Immunoglobulins, Intravenous; Immunosu

2017
Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy.
    The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11

    Topics: Anti-Inflammatory Agents; Azathioprine; Humans; Immunologic Factors; Immunosuppressive Agents; Inter

2010
Cytotoxic drugs and interferons for chronic inflammatory demyelinating polyradiculoneuropathy.
    The Cochrane database of systematic reviews, 2003, Issue:1

    Topics: Anti-Inflammatory Agents; Azathioprine; Cyclophosphamide; Cyclosporine; Humans; Immunologic Factors;

2003
Cytotoxic drugs and interferons for chronic inflammatory demyelinating polyradiculoneuropathy.
    The Cochrane database of systematic reviews, 2004, Oct-18, Issue:4

    Topics: Anti-Inflammatory Agents; Azathioprine; Cyclophosphamide; Cyclosporine; Humans; Immunologic Factors;

2004

Trials

1 trial available for azathioprine and Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

ArticleYear
Chronic inflammatory demyelinating polyradiculoneuropathy: long-term course and treatment of 60 patients.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2000, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Child; Cyclophosphamide; Electrophy

2000

Other Studies

22 other studies available for azathioprine and Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

ArticleYear
Two Case Reports of Chronic Inflammatory Demyelinating Polyneuropathy After COVID-19 Vaccination.
    Journal of Korean medical science, 2023, Feb-27, Volume: 38, Issue:8

    Topics: 2019-nCoV Vaccine mRNA-1273; Ad26COVS1; Aged; Azathioprine; COVID-19; COVID-19 Vaccines; Guillain-Ba

2023
Pediatric-Onset Chronic Inflammatory Demyelinating Polyneuropathy: A Multicenter Study.
    Pediatric neurology, 2023, Volume: 145

    Topics: Azathioprine; Child; Female; Humans; Immunoglobulins, Intravenous; Male; Methotrexate; Polyradiculon

2023
Efficacy of azathioprine and methotrexate in patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:4(Special)

    Topics: Adolescent; Adult; Azathioprine; Humans; Immunosuppressive Agents; Methotrexate; Polyradiculoneuropa

2023
Chronic inflammatory demyelinating polyneuropathy: Plasmapheresis or cyclosporine can be good treatment options in refractory cases.
    Neuromuscular disorders : NMD, 2019, Volume: 29, Issue:9

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Cyclosporine; Disease Progression; Female; Glucoc

2019
Rituximab in refractory chronic inflammatory demyelinating polyneuropathy.
    Muscle & nerve, 2020, Volume: 61, Issue:5

    Topics: Adult; Aged; Azathioprine; Canes; Cyclophosphamide; Female; Foot Orthoses; Glucocorticoids; Humans;

2020
A case of combined central and peripheral demyelination in Zambia.
    Multiple sclerosis and related disorders, 2020, Volume: 40

    Topics: Adult; Azathioprine; Comorbidity; Demyelinating Diseases; Developing Countries; Glucocorticoids; Hum

2020
Chronic inflammatory axonal polyneuropathy.
    Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:11

    Topics: Adolescent; Adult; Aged; Autoimmune Diseases of the Nervous System; Axons; Azathioprine; Biopsy; Chi

2020
Clinical Characteristics and Treatment Response of Chronic Inflammatory Demyelinating Polyradiculoneuropathy.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2017, Volume: 100, Issue:3

    Topics: Adult; Aged; Azathioprine; Drug Therapy, Combination; Female; Humans; Immunization, Passive; Immunos

2017
CIDP variants in diabetes: measuring treatment response with a small nerve fiber test.
    Journal of diabetes and its complications, 2015, Volume: 29, Issue:2

    Topics: Autonomic Nervous System; Azathioprine; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diabet

2015
Childhood CIDP: Study of 31 patients and comparison between slow and rapid-onset groups.
    Brain & development, 2015, Volume: 37, Issue:10

    Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Child; Child, Preschool; Disease Progression; Ear

2015
Acute-onset chronic inflammatory demyelinating polyneuropathy in hantavirus and hepatitis B virus coinfection: A case report.
    Medicine, 2016, Volume: 95, Issue:49

    Topics: Acute Disease; Adult; Azathioprine; Carrier State; Coinfection; Exercise Therapy; Follow-Up Studies;

2016
A 69-year-old man with left hemispheric necrotizing mass lesion.
    Brain pathology (Zurich, Switzerland), 2009, Volume: 19, Issue:3

    Topics: Aged; Azathioprine; Brain; Brain Stem; Encephalitis, Viral; Epstein-Barr Virus Infections; Humans; I

2009
Immunosuppressive treatment in refractory chronic inflammatory demyelinating polyradiculoneuropathy. A nationwide retrospective analysis.
    European journal of neurology, 2011, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Axons; Azathioprine; Child; Cycloph

2011
Long-term efficacy of interferon-alpha in chronic inflammatory demyelinating polyneuropathy.
    Journal of neurology, 2002, Volume: 249, Issue:6

    Topics: Axons; Azathioprine; Cyclophosphamide; Disease Progression; Drug Administration Schedule; Female; Hu

2002
Chronic inflammatory demyelinating polyradiculoneuropathy in diabetic patients.
    Muscle & nerve, 2003, Volume: 27, Issue:4

    Topics: Adjuvants, Immunologic; Adult; Azathioprine; Diabetic Neuropathies; Female; Humans; Immunoglobulins,

2003
Sustained remission of CIDP associated with Evans syndrome.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclon

2004
Long-standing idiopathic hypoparathyroidism masking coexistent chronic inflammatory demyelinating polyneuropathy.
    Journal of the peripheral nervous system : JPNS, 2004, Volume: 9, Issue:4

    Topics: Adolescent; Azathioprine; Calcium; Humans; Hypoparathyroidism; Immunoglobulins, Intravenous; Immunos

2004
Chronic inflammatory demyelinating polyneuropathy and respiratory failure.
    Journal of neurology, 2005, Volume: 252, Issue:10

    Topics: Aged; Azathioprine; Biopsy; Coma; Cyclophosphamide; Electromyography; Female; Follow-Up Studies; Hum

2005
Chronic inflammatory demyelinating polyneuropathy: a 6-year retrospective clinical study of a hospital-based population.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2007, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Biopsy; Demyelinating Diseases; Female; Gr

2007
Evolution and treatment of childhood chronic inflammatory polyneuropathy.
    Pediatric neurology, 2007, Volume: 36, Issue:2

    Topics: Acute Disease; Adolescent; Azathioprine; Child; Child, Preschool; Disease Progression; Female; Gluco

2007
Chronic inflammatory demyelinating polyneuropathy in a diabetic patient: deterioration after intravenous immunoglobulins treatment and favorable response to steroid treatment.
    Acta neurologica Belgica, 2007, Volume: 107, Issue:1

    Topics: Azathioprine; Diabetic Neuropathies; Disease Progression; Female; Humans; Immunoglobulins, Intraveno

2007
CIDP cured by allogeneic hematopoietic stem cell transplantation.
    European journal of neurology, 2007, Volume: 14, Issue:8

    Topics: Adult; Alopecia; Anemia, Aplastic; Azathioprine; Cyclophosphamide; Female; Graft vs Host Disease; He

2007