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azathioprine and Polyneuropathies

azathioprine has been researched along with Polyneuropathies in 24 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.

Research Excerpts

ExcerptRelevanceReference
"IR-CAP could well be 'axonal CIDP' in view of clinical similarity, but not proven as yet."1.56Chronic inflammatory axonal polyneuropathy. ( Alsharabati, M; King, P; Lu, L; Morgan, MB; Oh, SJ, 2020)
"Acute transverse myelitis (ATM) is an inflammatory process involving a restricted area of the spinal cord."1.33A case of Sjögren's syndrome with acute transverse myelitis and polyneuropathy in a patient free of sicca symptoms. ( Tristano, AG, 2006)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's5 (20.83)18.2507
2000's4 (16.67)29.6817
2010's2 (8.33)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Hari, G1
Skeik, N1
Oh, SJ1
Lu, L1
Alsharabati, M1
Morgan, MB1
King, P1
Henes, J1
Horger, M1
Kanz, L1
Kötter, I1
Sokumbi, O1
Wetter, DA1
Makol, A1
Warrington, KJ1
Sifuentes Giraldo, WA1
de la Puente Bujidos, C1
de Blas Beorlegui, G1
López San Román, A1
Peña Arrebola, A1
Hinrichs, R1
Schneider, LA1
Ozdemir, C1
Staib, G1
Scharffetter- Kochanek, K1
Tristano, AG1
Shio, K1
Kobayashi, H1
Ikeda, T1
Fukaya, E1
Iwadate, H1
Hikichi, T1
Sekine, H1
Watanabe, H1
Obara, K1
Sato, Y1
Pentland, B1
Adams, GG1
Mawdsley, C1
Trautmann, F1
Krämer, G1
Poralla, T1
Eckhardt, R1
Arnold, W1
Meyer zum Büschenfelde, KH1
Farthing, MJ1
Coxon, AY1
Sheaff, PC1
Pedrazzi, P1
Deruaz, JP1
Regli, F1
Mancuso, A1
Ardita, FV1
Leonardi, J1
Scuderi, M1
Börnke, C1
Przuntek, H1
Postert, T1
Schwechheimer, K1
Büttner, T1
Ullrich, J1
Rosenberger, K1
Sivaram, CA1
Kapur, S1
Rao, NS1
Chopra, JS1
Baba, M1
Matsunaga, M1
Riedel, RR1
Schmitt, A1
de Jonge, JP1
Hartmann, A1
Engelhardt, A1
Thron, C1
Glötzner, FL1
Neundörfer, B1
Wiethölter, H1
Yuill, GM1
Swinburn, WR1
Liversedge, LA1
Schilling, F1
Fossati, P1
Racadot, A1
Lefebvre, J1
Decoulx, M1
Linquette, M1

Reviews

2 reviews available for azathioprine and Polyneuropathies

ArticleYear
Digital ischemia in Behçet's disease: case-based review.
    Rheumatology international, 2020, Volume: 40, Issue:1

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Aspirin; Azathioprine; Behcet Syndrome; Colchicine;

2020
[Chronic inflammatory demyelinating polyneuropathy: multifocal demyelinating neuropathy].
    No to shinkei = Brain and nerve, 1992, Volume: 44, Issue:8

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Chronic Disease; Demyelinating Diseases; Female; Human

1992

Other Studies

22 other studies available for azathioprine and Polyneuropathies

ArticleYear
Chronic inflammatory axonal polyneuropathy.
    Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:11

    Topics: Adolescent; Adult; Aged; Autoimmune Diseases of the Nervous System; Axons; Azathioprine; Biopsy; Chi

2020
[56-year-old patient with leg paresis, pulmonary infiltrates, and eosinophilia--Case 08/2009].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:44

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Azathioprine; Churg-Strauss Syndrom

2009
Vasculitis associated with tumor necrosis factor-α inhibitors.
    Mayo Clinic proceedings, 2012, Volume: 87, Issue:8

    Topics: Adalimumab; Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, H

2012
Herpes zoster motor neuropathy in a patient with previous motor paresis secondary to Vogt-Koyanagi-Harada disease.
    American journal of physical medicine & rehabilitation, 2013, Volume: 92, Issue:4

    Topics: Adult; Azathioprine; Colitis, Ulcerative; Disease Progression; Electromyography; Female; Herpes Zost

2013
Azathioprine hypersensitivity in a patient with peripheral demyelinating polyneuropathy.
    The British journal of dermatology, 2003, Volume: 148, Issue:5

    Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Methyltransfera

2003
A case of Sjögren's syndrome with acute transverse myelitis and polyneuropathy in a patient free of sicca symptoms.
    Clinical rheumatology, 2006, Volume: 25, Issue:1

    Topics: Acute Disease; Adult; Azathioprine; Biopsy; Cyclophosphamide; Drug Therapy, Combination; Female; Hum

2006
[Nonsystemic vasculitic neuropathy treated with steroid and azathioprine].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2005, Jul-10, Volume: 94, Issue:7

    Topics: Aged; Azathioprine; Fever of Unknown Origin; Humans; Immunosuppressive Agents; Male; Peripheral Nerv

2005
Chronic idiopathic polyneuropathy treated with azathioprine.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:10

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Azathioprine; Chronic Disease; Dose-Response Relatio

1982
[Systemic lupus erythematosus. Brown-Sequard syndrome, spinal ataxia and peripheral polyneuropathy as the sole manifestations].
    Deutsche medizinische Wochenschrift (1946), 1984, Jun-29, Volume: 109, Issue:26

    Topics: Aged; Antibodies, Antinuclear; Ataxia; Autoantibodies; Azathioprine; DNA; Female; Humans; Liver Cirr

1984
Polyneuritis associated with azathioprine sensitivity reaction.
    British medical journal, 1980, Feb-09, Volume: 280, Issue:6211

    Topics: Adult; Azathioprine; Crohn Disease; Humans; Male; Polyneuropathies

1980
[Neuritis of multiple cranial nerves in idiopathic focal pachymeningitis].
    Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985), 1995, Volume: 146, Issue:6

    Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Biopsy; Cranial Nerve Diseases; Diagnostic Imaging; Hum

1995
Interferon alpha-2a therapy and pregnancy. Report of a case of chronic inflammatory demyelinating polyneuropathy.
    Acta obstetricia et gynecologica Scandinavica, 1998, Volume: 77, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Chronic Disease; Demyelinating Diseases; Female; Human

1998
Atypical multiple sclerosis presenting as chronic-progressive encephalomyelitis with polyneuritis and recurrent aseptic meningitis.
    Journal of neurology, 1999, Volume: 246, Issue:2

    Topics: Ataxia; Autoimmune Diseases; Azathioprine; Biopsy; Brain; Encephalomyelitis; Gliosis; Humans; Immuno

1999
[Treatment of periarteriitis nodosa with azathioprine - story of a case (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1975, Volume: 32, Issue:11

    Topics: Azathioprine; Humans; Male; Middle Aged; Polyarteritis Nodosa; Polyneuropathies; Syndrome

1975
[Vascular polyneuropathy in rheumatoid arthritis (author's transl)].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1977, Volume: 45, Issue:10

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Azathioprine; Humans; Male; Middle Aged; Penicillami

1977
Infective polyneuritis treated with azathioprine (a case report).
    Neurology India, 1975, Volume: 23, Issue:2

    Topics: Azathioprine; Female; Humans; Middle Aged; Polyneuropathies

1975
Gastrointestinal type 1 hypersensitivity to azathioprine.
    Klinische Wochenschrift, 1990, Jan-04, Volume: 68, Issue:1

    Topics: Azathioprine; Drug Hypersensitivity; Edema; Eosinophilia; Gastroenteritis; Humans; Intestinal Mucosa

1990
[Polyneuropathy in Churg-Strauss syndrome].
    Deutsche medizinische Wochenschrift (1946), 1989, Jun-09, Volume: 114, Issue:23

    Topics: Aged; Asthma; Azathioprine; Biopsy; Blood Sedimentation; Chronic Disease; Churg-Strauss Syndrome; Dr

1989
[Therapy of polyneuritis].
    Deutsche medizinische Wochenschrift (1946), 1986, Mar-14, Volume: 111, Issue:11

    Topics: Adrenal Cortex Hormones; Azathioprine; Humans; Plasmapheresis; Polyneuropathies; Polyradiculoneuropa

1986
Treatment of polyneuropathy with azathioprine.
    Lancet (London, England), 1970, Oct-24, Volume: 2, Issue:7678

    Topics: Acute Disease; Adult; Azathioprine; Chronic Disease; Female; Humans; Immunosuppressive Agents; Leuko

1970
["Rheumatoid" polyneuropathia].
    Deutsche medizinische Wochenschrift (1946), 1972, Dec-08, Volume: 97, Issue:49

    Topics: Arthritis, Rheumatoid; Azathioprine; Humans; Polyneuropathies

1972
[Action of azathioprine on a biological syndrome of alcoholic liver disease].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1968, Volume: 13, Issue:8

    Topics: Adult; Alcoholism; Azathioprine; Female; Hepatomegaly; Humans; Polyneuropathies

1968