azathioprine has been researched along with Polymyalgia Rheumatica in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Polymyalgia Rheumatica: A syndrome in the elderly characterized by proximal joint and muscle pain, high erythrocyte sedimentation rate, and a self-limiting course. Pain is usually accompanied by evidence of an inflammatory reaction. Women are affected twice as commonly as men and Caucasians more frequently than other groups. The condition is frequently associated with GIANT CELL ARTERITIS and some theories pose the possibility that the two diseases arise from a single etiology or even that they are the same entity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ability of azathioprine to reduce the maintenance prednisolone requirement of 31 patients with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA), or both, was tested in a double-blind placebo controlled study over one year." | 9.06 | Azathioprine in giant cell arteritis/polymyalgia rheumatica: a double-blind study. ( De Silva, M; Hazleman, BL, 1986) |
| "The ability of azathioprine to reduce the maintenance prednisolone requirement of 31 patients with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA), or both, was tested in a double-blind placebo controlled study over one year." | 5.06 | Azathioprine in giant cell arteritis/polymyalgia rheumatica: a double-blind study. ( De Silva, M; Hazleman, BL, 1986) |
| "We have described a 60-year-old woman with polymyalgia rheumatica treated initially with prednisone but ultimately with azathioprine and cyclophosphamide." | 3.67 | Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation. ( Canter, HG; Manz, HJ; Melton, J, 1986) |
| "Polymyalgia rheumatica (PMR)/temporal arteritis (TA) frequently causes significant morbidity in patients older than 50 years of age." | 2.41 | Polymyalgia rheumatica/temporal arteritis: recent advances. ( Barilla-LaBarca, ML; Brasington, RD; Lenschow, DJ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barilla-LaBarca, ML | 1 |
| Lenschow, DJ | 1 |
| Brasington, RD | 1 |
| Lovschall, S | 1 |
| Roig López de los Mozos, A | 1 |
| Calvo Catalá, J | 1 |
| Hortelano Martínez, E | 1 |
| Liñana Santafé, JJ | 1 |
| González-Cruz Cervellera, MI | 1 |
| Ballester Belda, JE | 1 |
| Reinhardt, U | 1 |
| De Silva, M | 1 |
| Hazleman, BL | 1 |
| Manz, HJ | 1 |
| Canter, HG | 1 |
| Melton, J | 1 |
| Lorenzen, I | 1 |
| Videbaek, A | 1 |
| Kaiser, H | 1 |
1 review available for azathioprine and Polymyalgia Rheumatica
| Article | Year |
|---|---|
Polymyalgia rheumatica/temporal arteritis: recent advances.
Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Cyclophosphamide; Dose-Response Relationship, Drug; Dru | 2002 |
1 trial available for azathioprine and Polymyalgia Rheumatica
| Article | Year |
|---|---|
Azathioprine in giant cell arteritis/polymyalgia rheumatica: a double-blind study.
Topics: Aged; Azathioprine; Clinical Trials as Topic; Double-Blind Method; Female; Giant Cell Arteritis; Hum | 1986 |
6 other studies available for azathioprine and Polymyalgia Rheumatica
| Article | Year |
|---|---|
[Azathioprine in the treatment of temporal arteritis and polymyalgia rheumatica].
Topics: Aged; Azathioprine; Back Pain; Drug Evaluation; Drug Therapy, Combination; Female; Fractures, Sponta | 1977 |
[Immunosuppressor treatment in temporal arteritis of long-term evolution].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chronic Disease; Female; Giant Cell Art | 1992 |
[Azathioprine therapy in polymyalgia rheumatica].
Topics: Aged; Azathioprine; Female; Humans; Polymyalgia Rheumatica; Prednisolone; Psychoses, Substance-Induc | 1989 |
Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation.
Topics: Azathioprine; Cranial Nerve Diseases; Cyclophosphamide; Drug Therapy, Combination; Female; Herpes Zo | 1986 |
Treatment of collagen diseases with cytostatics.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anemia, Hemolytic, Autoimmune; Arthritis, Rheumatoid; Asthma; | 1965 |
[Polymyalgia rheumatica].
Topics: Age Factors; Aged; Autoimmune Diseases; Azathioprine; Biopsy; Female; Giant Cell Arteritis; Humans; | 1974 |