azathioprine has been researched along with Peripheral Nervous System Diseases in 16 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A woman, aged 58, who had undergone prolonged treatment with corticosteroids for generalized necrotizing vasculitis, and had received azathioprine (Imurel) for 18 months, 4 years after discontinuing the latter treatment, developed peripheral neuropathy and a rapidly progressing cerebral disorder suggesting a basal meningeal process." | 3.66 | Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression. ( Jellinger, K; Kothbauer, P; Sunder-Plassmann, E; Weiss, R, 1979) |
| "When unrecognized and therefore untreated, vasculitis of the nervous system leads to pervasive injury and disability making this a disorder of paramount importance to all clinicians." | 2.42 | Vasculitis of the nervous system. ( Younger, DS, 2004) |
| "A man with multicentric angiofollicular lymph node hyperplasia and a polyclonal gammopathy developed a debilitating sensory-motor peripheral neuropathy that resolved with plasma-pheresis and immunosuppressive therapy." | 2.38 | Angiofollicular lymph node hyperplasia and peripheral neuropathy. Case report and literature review. ( May, E; Scherokman, B; Vukelja, SJ, 1991) |
| "Hydroxychloroquine was most frequently used (88." | 1.62 | Clinical features and outcomes from the Singapore Sjögren's syndrome study. ( Charan, N; Kam, JK; Leong, RW; Loh, ZW; Thong, BY, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (56.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Kam, JK | 1 |
| Charan, N | 1 |
| Leong, RW | 1 |
| Loh, ZW | 1 |
| Thong, BY | 1 |
| Filosto, M | 1 |
| Cavallaro, T | 1 |
| Pasolini, G | 1 |
| Broglio, L | 1 |
| Tentorio, M | 1 |
| Cotelli, M | 1 |
| Ferrari, S | 1 |
| Padovani, A | 1 |
| Younger, DS | 1 |
| Shio, K | 1 |
| Kobayashi, H | 1 |
| Ikeda, T | 1 |
| Fukaya, E | 1 |
| Iwadate, H | 1 |
| Hikichi, T | 1 |
| Sekine, H | 1 |
| Watanabe, H | 1 |
| Obara, K | 1 |
| Sato, Y | 1 |
| Campellone, JV | 1 |
| Hageboutros, A | 1 |
| Cohen, RD | 1 |
| Conn, DL | 1 |
| Ilstrup, DM | 1 |
| Hughes, RA | 1 |
| Cameron, JS | 1 |
| Hall, SM | 1 |
| Heaton, J | 1 |
| Payan, J | 1 |
| Teoh, R | 1 |
| Pentland, B | 1 |
| Streib, EW | 1 |
| Sun, SF | 1 |
| Jellinger, K | 1 |
| Kothbauer, P | 1 |
| Weiss, R | 1 |
| Sunder-Plassmann, E | 1 |
| Miller, RG | 1 |
| Scherokman, B | 1 |
| Vukelja, SJ | 1 |
| May, E | 1 |
| Yuill, GM | 1 |
| Swinburn, WR | 1 |
| Liversedge, LA | 1 |
| Heathfield, K | 1 |
| Dallos, V | 1 |
| Gye, RS | 1 |
| Hargrave, JC | 1 |
| Loewenthal, J | 1 |
| McLeod, JG | 1 |
| Pollard, JD | 1 |
| Booth, GC | 1 |
| Marmor, L | 1 |
3 reviews available for azathioprine and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Vasculitis of the nervous system.
Topics: Azathioprine; Connective Tissue Diseases; Cyclophosphamide; Diagnosis, Differential; Giant Cell Arte | 2004 |
Neuropathies and myopathies complicating HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Action Potentials; Adult; Antiviral Agents; Azathioprine; Combin | 1991 |
Angiofollicular lymph node hyperplasia and peripheral neuropathy. Case report and literature review.
Topics: Aged; Azathioprine; Castleman Disease; Humans; Immunosuppression Therapy; Male; Peripheral Nervous S | 1991 |
13 other studies available for azathioprine and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Clinical features and outcomes from the Singapore Sjögren's syndrome study.
Topics: Adult; Arthralgia; Azathioprine; Female; Humans; Hydroxychloroquine; Keratoconjunctivitis Sicca; Mal | 2021 |
Idiopathic hypocomplementemic urticarial vasculitis-linked neuropathy.
Topics: Anti-Inflammatory Agents; Axons; Azathioprine; Biopsy; Complement System Proteins; Drug Therapy, Com | 2009 |
[Nonsystemic vasculitic neuropathy treated with steroid and azathioprine].
Topics: Aged; Azathioprine; Fever of Unknown Origin; Humans; Immunosuppressive Agents; Male; Peripheral Nerv | 2005 |
Adie's pupils in paraneoplastic ganglionopathy with ANNA-1.
Topics: Aged; Antibodies, Neoplasm; Autonomic Nervous System Diseases; Azathioprine; Carcinoma, Small Cell; | 2006 |
Clinical features, prognosis, and response to treatment in polyarteritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cyclophosphamide; Female; Follow-Up | 1980 |
Multiple mononeuropathy as the initial presentation of systemic lupus erythematosus--nerve biopsy and response to plasma exchange.
Topics: Azathioprine; Biopsy; Diagnosis, Differential; Extremities; Female; Humans; Lupus Erythematosus, Sys | 1982 |
Azathioprine in chronic relapsing idiopathic polyneuropathy.
Topics: Adult; Azathioprine; Chronic Disease; Female; Humans; Peripheral Nervous System Diseases | 1980 |
Acquired demyelinative polyneuropathy: diagnosis and treatment with special reference to immunosuppressive therapy.
Topics: Adult; Azathioprine; Demyelinating Diseases; Female; Humans; Immunosuppressive Agents; Male; Middle | 1984 |
Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression.
Topics: Azathioprine; Brain Neoplasms; Female; Humans; Immunosuppressive Agents; Lymphoma; Middle Aged; Necr | 1979 |
Treatment of polyneuropathy with azathioprine.
Topics: Acute Disease; Adult; Azathioprine; Chronic Disease; Female; Humans; Immunosuppressive Agents; Leuko | 1970 |
Treatment of polyneuropathy with azathioprine.
Topics: Azathioprine; Female; Humans; Middle Aged; Peripheral Nervous System Diseases | 1970 |
Use of immunosuppressive agents in human nerve grafting.
Topics: Adolescent; Adult; Azathioprine; Humans; Leprosy; Median Nerve; Methods; Peripheral Nerve Injuries; | 1972 |
Nerve grafting in peripheral nerve.
Topics: Animals; Azathioprine; Female; Graft Rejection; Humans; Immunosuppression Therapy; Male; Peripheral | 1972 |