Page last updated: 2024-10-23

azathioprine and Peripheral Nerve Diseases

azathioprine has been researched along with Peripheral Nerve Diseases in 16 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"A woman, aged 58, who had undergone prolonged treatment with corticosteroids for generalized necrotizing vasculitis, and had received azathioprine (Imurel) for 18 months, 4 years after discontinuing the latter treatment, developed peripheral neuropathy and a rapidly progressing cerebral disorder suggesting a basal meningeal process."3.66Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression. ( Jellinger, K; Kothbauer, P; Sunder-Plassmann, E; Weiss, R, 1979)
"When unrecognized and therefore untreated, vasculitis of the nervous system leads to pervasive injury and disability making this a disorder of paramount importance to all clinicians."2.42Vasculitis of the nervous system. ( Younger, DS, 2004)
"A man with multicentric angiofollicular lymph node hyperplasia and a polyclonal gammopathy developed a debilitating sensory-motor peripheral neuropathy that resolved with plasma-pheresis and immunosuppressive therapy."2.38Angiofollicular lymph node hyperplasia and peripheral neuropathy. Case report and literature review. ( May, E; Scherokman, B; Vukelja, SJ, 1991)
"Hydroxychloroquine was most frequently used (88."1.62Clinical features and outcomes from the Singapore Sjögren's syndrome study. ( Charan, N; Kam, JK; Leong, RW; Loh, ZW; Thong, BY, 2021)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's2 (12.50)18.2507
2000's4 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Kam, JK1
Charan, N1
Leong, RW1
Loh, ZW1
Thong, BY1
Filosto, M1
Cavallaro, T1
Pasolini, G1
Broglio, L1
Tentorio, M1
Cotelli, M1
Ferrari, S1
Padovani, A1
Younger, DS1
Shio, K1
Kobayashi, H1
Ikeda, T1
Fukaya, E1
Iwadate, H1
Hikichi, T1
Sekine, H1
Watanabe, H1
Obara, K1
Sato, Y1
Campellone, JV1
Hageboutros, A1
Cohen, RD1
Conn, DL1
Ilstrup, DM1
Hughes, RA1
Cameron, JS1
Hall, SM1
Heaton, J1
Payan, J1
Teoh, R1
Pentland, B1
Streib, EW1
Sun, SF1
Jellinger, K1
Kothbauer, P1
Weiss, R1
Sunder-Plassmann, E1
Miller, RG1
Scherokman, B1
Vukelja, SJ1
May, E1
Yuill, GM1
Swinburn, WR1
Liversedge, LA1
Heathfield, K1
Dallos, V1
Gye, RS1
Hargrave, JC1
Loewenthal, J1
McLeod, JG1
Pollard, JD1
Booth, GC1
Marmor, L1

Reviews

3 reviews available for azathioprine and Peripheral Nerve Diseases

ArticleYear
Vasculitis of the nervous system.
    Current opinion in neurology, 2004, Volume: 17, Issue:3

    Topics: Azathioprine; Connective Tissue Diseases; Cyclophosphamide; Diagnosis, Differential; Giant Cell Arte

2004
Neuropathies and myopathies complicating HIV infection.
    Journal of clinical apheresis, 1991, Volume: 6, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Action Potentials; Adult; Antiviral Agents; Azathioprine; Combin

1991
Angiofollicular lymph node hyperplasia and peripheral neuropathy. Case report and literature review.
    Archives of internal medicine, 1991, Volume: 151, Issue:4

    Topics: Aged; Azathioprine; Castleman Disease; Humans; Immunosuppression Therapy; Male; Peripheral Nervous S

1991

Other Studies

13 other studies available for azathioprine and Peripheral Nerve Diseases

ArticleYear
Clinical features and outcomes from the Singapore Sjögren's syndrome study.
    Lupus, 2021, Volume: 30, Issue:2

    Topics: Adult; Arthralgia; Azathioprine; Female; Humans; Hydroxychloroquine; Keratoconjunctivitis Sicca; Mal

2021
Idiopathic hypocomplementemic urticarial vasculitis-linked neuropathy.
    Journal of the neurological sciences, 2009, Sep-15, Volume: 284, Issue:1-2

    Topics: Anti-Inflammatory Agents; Axons; Azathioprine; Biopsy; Complement System Proteins; Drug Therapy, Com

2009
[Nonsystemic vasculitic neuropathy treated with steroid and azathioprine].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2005, Jul-10, Volume: 94, Issue:7

    Topics: Aged; Azathioprine; Fever of Unknown Origin; Humans; Immunosuppressive Agents; Male; Peripheral Nerv

2005
Adie's pupils in paraneoplastic ganglionopathy with ANNA-1.
    Clinical neurology and neurosurgery, 2006, Volume: 108, Issue:7

    Topics: Aged; Antibodies, Neoplasm; Autonomic Nervous System Diseases; Azathioprine; Carcinoma, Small Cell;

2006
Clinical features, prognosis, and response to treatment in polyarteritis.
    Mayo Clinic proceedings, 1980, Volume: 55, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cyclophosphamide; Female; Follow-Up

1980
Multiple mononeuropathy as the initial presentation of systemic lupus erythematosus--nerve biopsy and response to plasma exchange.
    Journal of neurology, 1982, Volume: 228, Issue:4

    Topics: Azathioprine; Biopsy; Diagnosis, Differential; Extremities; Female; Humans; Lupus Erythematosus, Sys

1982
Azathioprine in chronic relapsing idiopathic polyneuropathy.
    Postgraduate medical journal, 1980, Volume: 56, Issue:660

    Topics: Adult; Azathioprine; Chronic Disease; Female; Humans; Peripheral Nervous System Diseases

1980
Acquired demyelinative polyneuropathy: diagnosis and treatment with special reference to immunosuppressive therapy.
    The Nebraska medical journal, 1984, Volume: 69, Issue:3

    Topics: Adult; Azathioprine; Demyelinating Diseases; Female; Humans; Immunosuppressive Agents; Male; Middle

1984
Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression.
    Journal of neurology, 1979, Jan-05, Volume: 220, Issue:4

    Topics: Azathioprine; Brain Neoplasms; Female; Humans; Immunosuppressive Agents; Lymphoma; Middle Aged; Necr

1979
Treatment of polyneuropathy with azathioprine.
    Lancet (London, England), 1970, Oct-24, Volume: 2, Issue:7678

    Topics: Acute Disease; Adult; Azathioprine; Chronic Disease; Female; Humans; Immunosuppressive Agents; Leuko

1970
Treatment of polyneuropathy with azathioprine.
    Lancet (London, England), 1970, Nov-14, Volume: 2, Issue:7681

    Topics: Azathioprine; Female; Humans; Middle Aged; Peripheral Nervous System Diseases

1970
Use of immunosuppressive agents in human nerve grafting.
    Lancet (London, England), 1972, Mar-25, Volume: 1, Issue:7752

    Topics: Adolescent; Adult; Azathioprine; Humans; Leprosy; Median Nerve; Methods; Peripheral Nerve Injuries;

1972
Nerve grafting in peripheral nerve.
    The Surgical clinics of North America, 1972, Volume: 52, Issue:5

    Topics: Animals; Azathioprine; Female; Graft Rejection; Humans; Immunosuppression Therapy; Male; Peripheral

1972