Page last updated: 2024-10-23

azathioprine and Pericarditis

azathioprine has been researched along with Pericarditis in 23 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Pericarditis: Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.

Research Excerpts

ExcerptRelevanceReference
"It is believed that pericarditis is yet another potential manifestation of hypersensitivity to this drug."5.30Azathioprine-induced pericarditis in a patient with ulcerative colitis. ( Simpson, CD, 1997)
"Recurrent pericarditis is a common and troublesome complication that affects 15%-30% of patients with a previous episode of pericarditis."3.01New Developments in the Management of Recurrent Pericarditis. ( Andreis, A; Collini, V; De Biasio, M; Franchin, L; Imazio, M; Mardigyan, V, 2023)
"Pericarditis is the most common form of pericardial disease and may be associated with significant morbidity and mortality."2.66Managing acute and recurrent idiopathic pericarditis. ( Cornelio, CK; Epperson, TM; Schwier, NC, 2020)
"Azathioprine was associated with more than half of patients becoming recurrence free; however, many patients required a restart of corticosteroids due to recurrence."2.55Treatment of Adults with Idiopathic Recurrent Pericarditis: Novel Use of Immunotherapy. ( Davies, ML; Hale, GM; Schwier, NC, 2017)
"Recurrent pericarditis is one of the most common and troublesome complications after an episode of pericarditis, and affects 20-50% of patients treated for pericarditis."2.53Recurrent pericarditis: new and emerging therapeutic options. ( Brucato, A; Gaita, F; Imazio, M; Lazaros, G, 2016)
"Recurrent pericarditis is one of the most troublesome complications of pericarditis occurring in about one third of patients with a previous attack of pericarditis."2.53Recurrent Pericarditis: Modern Approach in 2016. ( Adler, Y; Charron, P; Imazio, M, 2016)
"Meningococcal meningitis is itself uncommon, with a morbidity of approximately 1."1.31[Secondary immunologically-caused myocarditis, pericarditis and exudative pleuritis due to meningococcal meningitis]. ( Berwing, K; Damaschke, HJ; Stange, K, 2001)
"It is believed that pericarditis is yet another potential manifestation of hypersensitivity to this drug."1.30Azathioprine-induced pericarditis in a patient with ulcerative colitis. ( Simpson, CD, 1997)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19907 (30.43)18.7374
1990's3 (13.04)18.2507
2000's4 (17.39)29.6817
2010's5 (21.74)24.3611
2020's4 (17.39)2.80

Authors

AuthorsStudies
Imazio, M3
Mardigyan, V1
Andreis, A1
Franchin, L1
De Biasio, M1
Collini, V1
Schwier, NC2
Cornelio, CK1
Epperson, TM1
Fanouriakis, A1
Tziolos, N1
Bertsias, G1
Boumpas, DT1
Hammami, AS1
Jellazi, M1
Arfa, S1
Daada, S1
Ben Hamda, K1
Achour, A1
Ouali, S1
Lazaros, G1
Brucato, A1
Gaita, F1
Adler, Y1
Charron, P1
Hale, GM1
Davies, ML1
Vianello, F1
Cinetto, F1
Cavraro, M1
Battisti, A1
Castelli, M1
Imbergamo, S1
Marcolongo, R1
Daumas, A1
Bernard, F1
Jacquier, A1
Rossi, P1
Francès, Y1
Granel, B1
DEPASQUALE, NP1
BURCH, GE1
PENA, E1
REEMTSMA, K1
Krzossok, S1
Benck, U1
van der Woude, FJ1
Braun, C1
Kato, T1
Shiratori, K1
Kobashigawa, T1
Hidaka, Y1
Stratta, P1
Cremona, R1
Lazzarich, E1
Quaglia, M1
Fenoglio, R1
Canavese, C1
Hosenpud, JD1
Montanaro, A1
Hart, MV1
Haines, JE1
Specht, HD1
Bennett, RM1
Kloster, FE1
Meyer, T1
Verwiebe, R1
Lorch, H1
Kreuzer, H1
Figulla, HR1
Maisch, B1
Simpson, CD1
Stange, K1
Damaschke, HJ1
Berwing, K1
Dobek, E1
Zaleska, T1
Jayson, MI1
Jones, DE1
Degeorges, M1
Passa, P1
Varin, G1
Godeau, P1
Herreman, G1
Ben Ismail, M1
Levassor, M1
Metzger, JP1
Asplen, CH1
Levine, HD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033]120 participants (Anticipated)Interventional2022-08-15Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for azathioprine and Pericarditis

ArticleYear
New Developments in the Management of Recurrent Pericarditis.
    The Canadian journal of cardiology, 2023, Volume: 39, Issue:8

    Topics: Adrenal Cortex Hormones; Azathioprine; Colchicine; Humans; Immunoglobulins, Intravenous; Pericarditi

2023
Managing acute and recurrent idiopathic pericarditis.
    JAAPA : official journal of the American Academy of Physician Assistants, 2020, Volume: 33, Issue:1

    Topics: Acute Disease; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azathiopri

2020
Update οn the diagnosis and management of systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc

2021
Recurrent pericarditis: new and emerging therapeutic options.
    Nature reviews. Cardiology, 2016, Volume: 13, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Azathioprine; Colchicine; Gl

2016
Recurrent Pericarditis: Modern Approach in 2016.
    Current cardiology reports, 2016, Volume: 18, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azathioprine; Colchicine; Drug Therapy, Combinatio

2016
Treatment of Adults with Idiopathic Recurrent Pericarditis: Novel Use of Immunotherapy.
    Pharmacotherapy, 2017, Volume: 37, Issue:3

    Topics: Adult; Azathioprine; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents

2017

Other Studies

17 other studies available for azathioprine and Pericarditis

ArticleYear
Getting to the heart of the matter: diagnostic tools and therapeutic approach to cardiac involvement in Behçet syndrome A Tunisian case series.
    Reumatismo, 2021, Apr-19, Volume: 73, Issue:1

    Topics: Adult; Azathioprine; Behcet Syndrome; Female; Humans; Male; Pericarditis; Retrospective Studies; Thr

2021
Azathioprine in isolated recurrent pericarditis: a single centre experience.
    International journal of cardiology, 2011, Mar-17, Volume: 147, Issue:3

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Female; Humans; Male; Middle Aged; Pericarditis; Retro

2011
[Eosinophilic myopericarditis revealing a Churg-Strauss syndrome].
    La Revue de medecine interne, 2011, Volume: 32, Issue:5

    Topics: Azathioprine; Churg-Strauss Syndrome; Cyclophosphamide; Diagnosis, Differential; Drug Therapy, Combi

2011
ELECTROCARDIOGRAPHIC STUDIES IN HOMOLOGOUS CANINE HEART TRANSPLANTATIONS.
    Circulation research, 1965, Volume: 16

    Topics: Animals; Azathioprine; Dogs; Electrocardiography; Heart; Heart Transplantation; Hydrocortisone; Kidn

1965
[Disseminated intravascular coagulation, perimyocarditis and bilateral pleural empyema in adult Still's disease].
    Deutsche medizinische Wochenschrift (1946), 2004, Nov-19, Volume: 129, Issue:47

    Topics: Adult; Azathioprine; Disseminated Intravascular Coagulation; Electrocardiography; Empyema, Pleural;

2004
Systemic lupus erythematosus with organic brain syndrome: serial electroencephalograms accurately evaluate therapeutic efficacy.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:2

    Topics: Azathioprine; Cerebrospinal Fluid; Cyclophosphamide; Disorders of Excessive Somnolence; Electroencep

2006
Life-threatening systemic flare-up of systemic lupus erythematosus following influenza vaccination.
    Lupus, 2008, Volume: 17, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Female; Humans; Immunosuppressive Agents; Influenza Vac

2008
Myocardial perfusion abnormalities in asymptomatic patients with systemic lupus erythematosus.
    The American journal of medicine, 1984, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Cicatrix; Coronary Disease; Exercise Test; Female; Heart; Humans; L

1984
[Involvement of the pericardium in Churg-Strauss syndrome].
    Zeitschrift fur Kardiologie, 1994, Volume: 83, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Churg-Strauss Syndrome; Cyclophosphamide; Drug Therapy

1994
[Comments on the contribution by M. Stille-Siegener et al. Myocarditis].
    Der Internist, 1994, Volume: 35, Issue:1

    Topics: Azathioprine; Biopsy; Combined Modality Therapy; Drug Therapy, Combination; Endocardium; Humans; Myo

1994
Azathioprine-induced pericarditis in a patient with ulcerative colitis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1997, Volume: 11, Issue:3

    Topics: Adult; Antimetabolites; Azathioprine; Colitis, Ulcerative; Diagnosis, Differential; Echocardiography

1997
[Secondary immunologically-caused myocarditis, pericarditis and exudative pleuritis due to meningococcal meningitis].
    Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Anticoagulants; Azathioprine; Diuretics, Osmotic; Echocardiogr

2001
[Posttraumatic recurrent pericarditis].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1977, Aug-08, Volume: 32, Issue:32

    Topics: Accidents, Traffic; Adult; Azathioprine; Humans; Male; Pericarditis; Recurrence

1977
Scleritis and rheumatoid arthritis.
    Annals of the rheumatic diseases, 1971, Volume: 30, Issue:4

    Topics: Adrenocorticotropic Hormone; Age Factors; Arteritis; Arthritis, Rheumatoid; Azathioprine; Betamethas

1971
[Dressler's syndrome relapsing during corticotherapy but cured with immunosuppressive agents].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Mar-14, Volume: 48, Issue:13

    Topics: Azathioprine; Humans; Indomethacin; Male; Middle Aged; Myocardial Infarction; Pericarditis; Pleurisy

1972
[Behcet's syndrome: pericardial and pulmonary lesions].
    La Nouvelle presse medicale, 1972, Feb-05, Volume: 1, Issue:6

    Topics: Adult; Azathioprine; Behcet Syndrome; Blood Coagulation Disorders; Electrocardiography; Female; Huma

1972
Azathioprine therapy of steroid-responsive pericarditis.
    American heart journal, 1970, Volume: 80, Issue:1

    Topics: Adult; Azathioprine; Electrocardiography; Female; Humans; Male; Middle Aged; Pericarditis; Prednison

1970