Page last updated: 2024-10-23

azathioprine and Pemphigoid

azathioprine has been researched along with Pemphigoid in 62 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"To investigate the safety and efficacy of oral methylprednisolone combined with azathioprine sodium or mycophenolate mofetil for the treatment of bullous pemphigoid."9.12A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid. ( Beissert, S; Böhm, M; Bonsmann, G; Frieling, U; Gollnick, H; Hunzelmann, N; Junghans, V; Luger, TA; Meurer, M; Pillekamp, H; Ruzicka, T; Rzany, B; Stadler, R; Sticherling, M; Werfel, T; Zillikens, D, 2007)
"We conclude that neither azathioprine nor plasma exchange is effective enough to be used routinely as an adjuvant to corticosteroids in the management of bullous pemphigoid."9.07Controlled trial of azathioprine and plasma exchange in addition to prednisolone in the treatment of bullous pemphigoid. ( Bernard, P; Foldès-Pauwels, C; Guillaume, JC; Guillot, B; Joly, P; Labeille, B; Picard, C; Prigent, F; Prost, C; Vaillant, L, 1993)
"Current treatment of bullous pemphigoid (BP) is based on the long-term use of topical and/or systemic corticosteroids, which are associated with a high rate of adverse events and increased mortality."6.84An open, multicentre, randomized clinical study in patients with bullous pemphigoid comparing methylprednisolone and azathioprine with methylprednisolone and dapsone. ( Aberer, E; Franke, A; Gläser, R; Hertl, M; Pfeiffer, C; Rzany, B; Schmidt, E; Schneider, S; Shimanovich, I; Sticherling, M; Werfel, T; Wilczek, A; Zillikens, D, 2017)
"Clobetasol propionate cream applied over the whole body is probably similarly effective as, and may cause less mortality than, oral prednisone for treating bullous pemphigoid."5.41Interventions for bullous pemphigoid. ( Anchan, VN; Boyle, RJ; Chi, CC; Kirtschig, G; Murrell, DF; Singh, S; Taghipour, K, 2023)
"To investigate the safety and efficacy of oral methylprednisolone combined with azathioprine sodium or mycophenolate mofetil for the treatment of bullous pemphigoid."5.12A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid. ( Beissert, S; Böhm, M; Bonsmann, G; Frieling, U; Gollnick, H; Hunzelmann, N; Junghans, V; Luger, TA; Meurer, M; Pillekamp, H; Ruzicka, T; Rzany, B; Stadler, R; Sticherling, M; Werfel, T; Zillikens, D, 2007)
"We conclude that neither azathioprine nor plasma exchange is effective enough to be used routinely as an adjuvant to corticosteroids in the management of bullous pemphigoid."5.07Controlled trial of azathioprine and plasma exchange in addition to prednisolone in the treatment of bullous pemphigoid. ( Bernard, P; Foldès-Pauwels, C; Guillaume, JC; Guillot, B; Joly, P; Labeille, B; Picard, C; Prigent, F; Prost, C; Vaillant, L, 1993)
"Preliminary data suggest a possible association between the use of azathioprine, cyclophosphamide, and cyclosporine and increased susceptibility to cancer in patients with pemphigus and pemphigoid."4.86Association between cancer and immunosuppressive therapy--analysis of selected studies in pemphigus and pemphigoid. ( Ahmed, AR; Christen, WG; Gürcan, HM; Keskin, DB; Mabrouk, D, 2010)
"Azathioprine has an important role in treatment of many inflammatory dermatoses."3.69Azathioprine in dermatology: a survey of current practice in the U.K. ( English, JS; Gawkrodger, DJ; Lear, JT; Tan, BB, 1997)
" We report two cases where multifocal Kaposi's sarcoma developed following iatrogenic immunosuppression with prednisolone and azathioprine for bullous pemphigoid."3.69Kaposi's sarcoma associated with immunosuppression for bullous pemphigoid. ( Cerio, R; Halpern, SM; Kirby, JT; Parslew, R; Sharpe, GR, 1997)
"Severe cases of pemphigus vulgaris should be treated with prednisone in high dosage (180-360 mg daily)."3.67[Therapy of pemphigus and pemphigoid]. ( Schaumburg-Lever, G, 1986)
"Current treatment of bullous pemphigoid (BP) is based on the long-term use of topical and/or systemic corticosteroids, which are associated with a high rate of adverse events and increased mortality."2.84An open, multicentre, randomized clinical study in patients with bullous pemphigoid comparing methylprednisolone and azathioprine with methylprednisolone and dapsone. ( Aberer, E; Franke, A; Gläser, R; Hertl, M; Pfeiffer, C; Rzany, B; Schmidt, E; Schneider, S; Shimanovich, I; Sticherling, M; Werfel, T; Wilczek, A; Zillikens, D, 2017)
"Bullous pemphigoid is the most common autoimmune bullous disease in the West."2.43Interventions for bullous pemphigoid. ( Hollis, S; Khumalo, N; Kirtschig, G; Middleton, P; Murrell, D; Wojnarowska, F, 2005)
"Bullous pemphigoid is an autoimmune skin blistering disorder that can present with several different degrees of severity."2.43Bullous pemphigoid treatment review. ( Korman, NJ; Patton, T, 2006)
"Bullous pemphigoid is the most common autoimmune bullous disease in the West."2.42Interventions for bullous pemphigoid. ( Hollis, S; Khumalo, N; Kirtschig, G; Middleton, P; Murrell, D; Wojnarowska, F, 2003)
"Azathioprine has been available for 30 years and is used in a variety of dermatologic conditions."2.38Azathioprine in dermatology. ( Colver, GB; Harris, DW; Younger, IR, 1991)
"Bullous pemphigoid is a rare, autoimmune blistering disease."1.38"Half-half" blisters in bullous pemphigoid successfully treated with adjuvant high-dose intravenous immunoglobulin. ( Filipe, P; Lopes, L; Marques, MS; Pacheco, D; Soares-Almeida, L, 2012)
"Several variants of bullous pemphigoid have been reported including pemphigoid nodularis."1.37Pemphigoid nodularis: a case report. ( Kalaaji, AN; Lehman, JS; Rogers, RS; Stone, RA, 2011)
"Bullous pemphigoid is the most frequent autoimmune blistering skin disease."1.31[Bullous pemphigoid, primary biliary cirrhosis and vitiligo: a multiple autoimmune syndrome?]. ( Géniaux, M; Marcet, B; Sibaud, V; Taieb, A, 2002)
" All patients went into remission with a lower daily dosage of oral prednisone at 3 and 6 months postplasmapheresis."1.31Plasmapheresis as a steroid saving procedure in bullous pemphigoid. ( Egan, CA; Meadows, KP; Zone, JJ, 2000)
"We describe the clinical presentation, treatment of Kaposi's sarcoma skin lesions in an immunosuppressed patient with bullous pemphigoid."1.30Identification of HHV-8 DNA in the skin lesions of Kaposi's sarcoma in an immunosuppressed patient with bullous pemphigoid. ( Gaspari, AA; Marchese, S; Powell, D; Rady, PL; Tyring, SK, 1997)
"Bullous pemphigoid is a clinically heterogeneous disease although little is known of the factors affecting its course and outcome."1.28Lack of predictive factors for the clinical course of bullous pemphigoid. ( Venning, VA; Wojnarowska, F, 1992)
"Bullous pemphigoid is an autoimmune bullous dermatosis that can be preceded by a prodromal phase, usually lasting weeks to months, during which the cutaneous changes are dermatitic rather than bullous."1.27The prodrome of bullous pemphigoid. ( Amato, DA; Silverstein, J; Zitelli, J, 1988)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199011 (17.74)18.7374
1990's13 (20.97)18.2507
2000's19 (30.65)29.6817
2010's15 (24.19)24.3611
2020's4 (6.45)2.80

Authors

AuthorsStudies
Yaïci, R1
Roth, M1
Juergens, L1
Nawaiseh, SA1
Burkhard, D1
Besgen, V1
Fuest, M1
Girbardt, C1
Hampel, U1
Heichel, J1
Heiligenhaus, A1
Herwig-Carl, MC1
Kakkassery, V1
Kontopoulou, K1
Löffler, KU1
Maier, PC1
Nölle, B1
Pach, J1
Paul, S1
Pleyer, U1
Pöllmann, M1
Saeger, M1
Schmidt, E4
Siebelmann, S1
Sokolenko, E1
Strudel, L1
Stübiger, N1
Tarhan, M1
Theuersbacher, J1
van Oterendorp, C1
Walker, M1
Wiecha, C1
Wykrota, AA1
Geerling, G1
Hsieh, CY1
Tsai, TF1
Singh, S1
Kirtschig, G5
Anchan, VN1
Chi, CC1
Taghipour, K1
Boyle, RJ1
Murrell, DF4
Holtsche, MM1
Hammers, CM1
Chakievska, L1
Ludwig, RJ1
Thaci, D1
Zillikens, D4
Sticherling, M2
Franke, A1
Aberer, E1
Gläser, R1
Hertl, M1
Pfeiffer, C1
Rzany, B2
Schneider, S1
Shimanovich, I1
Werfel, T2
Wilczek, A1
Kakuta, R1
Yamagami, J1
Funakoshi, T1
Takahashi, H1
Ohyama, M1
Amagai, M1
Patsatsi, A1
Kyriakou, A1
Werth, VP1
Cruz, MJ1
Santos, P1
Morais, P1
Barreto, F1
Azevedo, F1
Imbernón-Moya, A1
Aguilar, A1
Burgos, F1
Gallego, MÁ1
Yamashita, C1
Nakamizo, S1
Honda, Y1
Dainichi, T1
Kabashima, K1
Bystryn, JC1
Recke, A1
Rose, C1
Bröcker, EB1
Sitaru, C1
Mabrouk, D1
Gürcan, HM1
Keskin, DB1
Christen, WG1
Ahmed, AR2
Middleton, P3
Bennett, C1
Wojnarowska, F5
Khumalo, NP2
Kusajima, E1
Akiyama, M1
Sato, M1
Natsuga, K1
Shimizu, H1
Bernard, P2
Charneux, J1
Daniel, BS1
Borradori, L1
Hall, RP1
Guilabert, A1
Lozano, F1
Iranzo, P1
Suárez-Casasús, B1
Martinez-De Pablo, I1
Julià, M1
Mascaró, JM1
Lehman, JS1
Kalaaji, AN1
Rogers, RS1
Stone, RA1
Nigam, R1
Levitt, J1
Pacheco, D1
Lopes, L1
Soares-Almeida, L1
Marques, MS1
Filipe, P1
Zachariae, CO1
Marcet, B1
Sibaud, V1
Géniaux, M1
Taieb, A1
Erbagci, Z1
Khumalo, N2
Hollis, S2
Murrell, D2
Burnett, PE1
Sakuma-Oyama, Y1
Powell, AM1
Albert, S1
Oyama, N1
Bhogal, BS1
Black, MM1
Kreuter, A1
Harati, A1
Breuckmann, F1
Appelhans, C1
Altmeyer, P1
Hofmann, SC1
Bruckner-Tuderman, L1
Patton, T1
Korman, NJ1
Beissert, S1
Frieling, U1
Böhm, M1
Stadler, R1
Hunzelmann, N1
Meurer, M1
Gollnick, H1
Ruzicka, T1
Pillekamp, H1
Junghans, V1
Bonsmann, G1
Luger, TA1
Leonard, N1
Biswas, A1
Hickey, S1
Bell, H1
Montag, H1
Gendler, E1
Levene, GM1
Olmos, L1
de Diego, V1
Foster, CS1
Wilson, LA1
Ekins, MB1
Jones, JJ1
Ashworth, J1
Anstey, A1
Guillaume, JC1
Vaillant, L1
Picard, C1
Prost, C1
Labeille, B1
Guillot, B1
Foldès-Pauwels, C1
Prigent, F1
Joly, P1
Tan, BB1
Lear, JT1
Gawkrodger, DJ1
English, JS1
Krunic, AL1
Kokai, D1
Bacetic, B1
Kesic, V1
Nikolic, MM1
Petkovic, S1
Clark, RE1
Halpern, SM1
Parslew, R1
Cerio, R1
Kirby, JT1
Sharpe, GR1
Gaspari, AA1
Marchese, S1
Powell, D1
Rady, PL1
Tyring, SK1
Primka, EJ1
Camisa, C1
Tavadia, SM1
Mydlarski, PR1
Reis, MD1
Mittmann, N1
Pinkerton, PH1
Shear, N1
Sauder, DN1
Egan, CA2
Meadows, KP1
Zone, JJ1
Yancey, KB1
Burgess, MJ1
Fivenson, DP1
Goulon, M1
Combes, A1
Chesneau, AM1
Bournérias, I1
Yamada, H1
Ogawa, H1
Venning, VA1
Younger, IR1
Harris, DW1
Colver, GB1
Rupprecht, M1
Stäbler, A1
Hornstein, OP1
Collison, DW1
Dahlberg, PJ1
Hogan, JD1
Bandemir, W1
Krëger, E1
Prasad, KK1
Chen, L1
Jeffes, EW1
Amato, DA1
Silverstein, J1
Zitelli, J1
Schaumburg-Lever, G1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of add-on Dapsone Versus add-on Methotrexate in Patients With Bullous Pemphigoid: A Randomized Controlled Trial[NCT05984381]Phase 462 participants (Anticipated)Interventional2023-08-01Recruiting
An Open Randomized Comparative Trial of Four Different Dressings for Cutaneous Coverage in Pemphigus and Pemphigoid[NCT02365675]12 participants (Anticipated)Interventional2015-01-31Recruiting
A Comparison of Oral Methylprednisolone Plus Azathioprine or Mycophenolate Mofetil for the Treatment of Bullous Pemphigoid[NCT00431119]Phase 270 participants Interventional1997-10-31Completed
Rituximab in the Treatment of Patients With Bullous Pemphigoid[NCT00286325]Phase 1/Phase 28 participants (Actual)Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

B Cell Number at Week 24

Peripheral blood B cell number at week 24 compared to B cell number at week 0 (NCT00286325)
Timeframe: Week 0 and at 24 weeks

InterventionB cells per microliter (Median)
Treated3.99

IgG Anti Bullous Pemphigoid (BP) 180 Measured in Units by ELISA at Week 24.

IgG antibodies against BP 180 measured in units (by ELISA) for each participant at week 0 compared to value at week 24, (NCT00286325)
Timeframe: Week 0 and at 24 weeks

InterventionElisa Units (Median)
Treated40.5

Number of Days to Cessation of New Blister

The first study visit in which patient reported and was confirmed to have no new blister or lesion formation . (NCT00286325)
Timeframe: 1 year

InterventionDays (Median)
Treated57

Systemic Corticosteroid Dose of 25% of Starting Dose or 10 mg/Day by Week 24

Subject systemic corticosteroid dosage at week 24 was 25% of starting dose or 10 mg/day of prednisone or less (NCT00286325)
Timeframe: 24 weeks

Interventionparticipants (Number)
Treated7

Primary Safety Endpoint

The primary safety endpoint is the occurrence of treatment emergent adverse events including infections, infusion reactions and disease progression. These were determined by clinical evaluation and laboratory questions. Disease progression is defined as development of new blisters despite therapy. These are reported as the number of participants with a study related SAE. (NCT00286325)
Timeframe: 1 year

Interventionparticipants (Number)
Treatment emergent adverse eventsInfusion reactionsDisease Progression
Treated001

Reviews

16 reviews available for azathioprine and Pemphigoid

ArticleYear
Management of Coexisting Bullous Pemphigoid and Psoriasis: A Review.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:6

    Topics: Acitretin; Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Biological Factors; Biologi

2022
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2023, 08-11, Volume: 8

    Topics: Azathioprine; Clobetasol; Dapsone; Doxycycline; Humans; Methylprednisolone; Niacinamide; Pemphigoid,

2023
Bullous pemphigoid in adolescence.
    Pediatric dermatology, 2019, Volume: 36, Issue:2

    Topics: Adolescent; Anti-Infective Agents; Azathioprine; Child; Dapsone; Female; Glucocorticoids; Humans; Im

2019
Erythema Multiforme-Like Bullous Pemphigoid.
    Actas dermo-sifiliograficas, 2016, Volume: 107, Issue:8

    Topics: Adult; Autoantibodies; Autoantigens; Azathioprine; Biopsy; Collagen Type XVII; Diagnosis, Differenti

2016
Transition from pemphigus foliaceus to bullous pemphigoid: intermolecular B-cell epitope spreading without IgG subclass shifting.
    Journal of the American Academy of Dermatology, 2009, Volume: 61, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Autoantibodies; Azathioprine; Biomarkers; Biopsy, Needle; Combined Mo

2009
Association between cancer and immunosuppressive therapy--analysis of selected studies in pemphigus and pemphigoid.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:11

    Topics: Azathioprine; Cyclophosphamide; Cyclosporine; Humans; Immunosuppressive Agents; Neoplasms; Pemphigoi

2010
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10

    Topics: Azathioprine; Clobetasol; Combined Modality Therapy; Drug Therapy, Combination; Drugs, Chinese Herba

2010
[Bullous pemphigoid: a review].
    Annales de dermatologie et de venereologie, 2011, Volume: 138, Issue:3

    Topics: Aged; Azathioprine; Clobetasol; Combined Modality Therapy; Dapsone; Dose-Response Relationship, Drug

2011
Evidence-based management of bullous pemphigoid.
    Dermatologic clinics, 2011, Volume: 29, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Autoantibodies; Azathioprine; Clinical Trials as Top

2011
Where does rituximab fit in the treatment of autoimmune mucocutaneous blistering skin disease?
    Journal of drugs in dermatology : JDD, 2012, Volume: 11, Issue:5

    Topics: Antibodies, Monoclonal, Murine-Derived; Azathioprine; Glucocorticoids; Humans; Immunologic Factors;

2012
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2003, Issue:3

    Topics: Azathioprine; Glucocorticoids; Humans; Immunosuppressive Agents; Niacinamide; Pemphigoid, Bullous; P

2003
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Azathioprine; Glucocorticoids; Humans; Immunosuppressive Agents; Niacinamide; Pemphigoid, Bullous; P

2005
Bullous pemphigoid treatment review.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:17

    Topics: Administration, Topical; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Cyclophosph

2006
The treatment of pemphigus and pemphigoid.
    Clinical and experimental dermatology, 1982, Volume: 7, Issue:6

    Topics: Aged; Azathioprine; Cosyntropin; Drug Therapy, Combination; Humans; Methylprednisolone; Pemphigoid,

1982
A systematic review of treatments for bullous pemphigoid.
    Archives of dermatology, 2002, Volume: 138, Issue:3

    Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Humans;

2002
A systematic review of treatments for bullous pemphigoid.
    Archives of dermatology, 2002, Volume: 138, Issue:3

    Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Humans;

2002
A systematic review of treatments for bullous pemphigoid.
    Archives of dermatology, 2002, Volume: 138, Issue:3

    Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Humans;

2002
A systematic review of treatments for bullous pemphigoid.
    Archives of dermatology, 2002, Volume: 138, Issue:3

    Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucocorticoids; Humans;

2002
Azathioprine in dermatology.
    Journal of the American Academy of Dermatology, 1991, Volume: 25, Issue:2 Pt 1

    Topics: Azathioprine; Drug Interactions; Eczema; Humans; Leukopenia; Pemphigoid, Bullous; Pemphigus; Skin Di

1991

Trials

4 trials available for azathioprine and Pemphigoid

ArticleYear
An open, multicentre, randomized clinical study in patients with bullous pemphigoid comparing methylprednisolone and azathioprine with methylprednisolone and dapsone.
    The British journal of dermatology, 2017, Volume: 177, Issue:5

    Topics: Administration, Oral; Adrenal Cortex Hormones; Aged; Azathioprine; Dapsone; Dermatologic Agents; Dru

2017
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid.
    Archives of dermatology, 2007, Volume: 143, Issue:12

    Topics: Administration, Oral; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Azathioprine; Dose-Response

2007
Controlled trial of azathioprine and plasma exchange in addition to prednisolone in the treatment of bullous pemphigoid.
    Archives of dermatology, 1993, Volume: 129, Issue:9

    Topics: Azathioprine; Combined Modality Therapy; Humans; Methyltransferases; Pemphigoid, Bullous; Plasma Exc

1993
Controlled trial of azathioprine and plasma exchange in addition to prednisolone in the treatment of bullous pemphigoid.
    Archives of dermatology, 1993, Volume: 129, Issue:1

    Topics: Aged; Azathioprine; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Male; Pemp

1993

Other Studies

42 other studies available for azathioprine and Pemphigoid

ArticleYear
On the Current Care Situation and Treatment of Ocular Mucous Membrane Pemphigoid in Germany.
    Klinische Monatsblatter fur Augenheilkunde, 2023, Volume: 240, Issue:9

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Mucous Membrane; Pemphigoid, Benign Mucous Membrane;

2023
Adjuvant treatment with secukinumab induced long term remission in a patient with severe bullous pemphigoid.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2020, Volume: 18, Issue:12

    Topics: Adjuvants, Immunologic; Antibodies, Monoclonal, Humanized; Azathioprine; Humans; Pemphigoid, Bullous

2020
Azathioprine monotherapy in autoimmune blistering diseases: A feasible option for mild to moderate cases.
    The Journal of dermatology, 2018, Volume: 45, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Feasibility Studies; Female; Humans; Immunosuppressive

2018
Refractory bullous pemphigoid with fatal outcome in a young patient.
    International journal of dermatology, 2013, Volume: 52, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Drug Resistan

2013
Combination therapy of prednisolone and i.v. immunoglobulin treatment decreases circulating interleukin-5 and eosinophils in a patient with bullous pemphigoid.
    The Journal of dermatology, 2017, Volume: 44, Issue:1

    Topics: Administration, Intravenous; Autoantibodies; Autoantigens; Azathioprine; Biopsy; Collagen Type XVII;

2017
Comparative effectiveness of azathioprine or mycophenolate mofetil as an adjuvant for the treatment of bullous pemphigoid.
    Archives of dermatology, 2008, Volume: 144, Issue:7

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Mycophenolic Acid; Pemphigoid, Bullous; Randomized C

2008
Type XVII collagen ELISA indices significantly decreased after bullous pemphigoid remission.
    International journal of dermatology, 2011, Volume: 50, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Azathioprine; Cohort Studies; Collagen

2011
A case of aggressive bullous pemphigoid associated with the defective functional variant of Fc gamma receptor IIb: implications for pathogenesis?
    Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:5

    Topics: Aged; Alleles; Autoantibodies; Autoantigens; Azathioprine; Collagen Type XVII; Cyclophosphamide; Dap

2011
Pemphigoid nodularis: a case report.
    Cutis, 2011, Volume: 88, Issue:5

    Topics: Aged; Antimetabolites; Azathioprine; Diagnosis, Differential; Female; Fluorescent Antibody Technique

2011
"Half-half" blisters in bullous pemphigoid successfully treated with adjuvant high-dose intravenous immunoglobulin.
    Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2012, Volume: 21, Issue:3

    Topics: Azathioprine; Blister; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Immunologic Factors; M

2012
Gabapentin-induced bullous pemphigoid.
    Acta dermato-venereologica, 2002, Volume: 82, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Azathioprine; Cyclohexanecarboxylic Acids; Drug Therapy, Combinat

2002
[Bullous pemphigoid, primary biliary cirrhosis and vitiligo: a multiple autoimmune syndrome?].
    Annales de medecine interne, 2002, Volume: 153, Issue:5

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Dermatologic Ag

2002
Childhood bullous pemphigoid following hepatitis B immunization.
    The Journal of dermatology, 2002, Volume: 29, Issue:12

    Topics: Adrenal Cortex Hormones; Azathioprine; Biopsy, Needle; Child; Drug Therapy, Combination; Female; Fol

2002
Bullous pemphigoid and psoriasis vulgaris.
    Dermatology online journal, 2003, Volume: 9, Issue:4

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Male; Middle Aged; Pemphigoid, Bullous; Psoriasis

2003
Lichen planus pemphigoides evolving into pemphigoid nodularis.
    Clinical and experimental dermatology, 2003, Volume: 28, Issue:6

    Topics: Autoantigens; Azathioprine; Carrier Proteins; Collagen Type XVII; Cytoskeletal Proteins; Dystonin; E

2003
Intravenous immune globulin in the treatment of persistent pemphigoid gestationis.
    Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:6

    Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Immunoglobulins, Intravenous; Immuno

2004
[Bullous pemphigoid: diagnostics and new therapeutic strategies].
    Deutsche medizinische Wochenschrift (1946), 2006, Feb-24, Volume: 131, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Biopsy

2006
Eosinophilic spongiosis in a case of lichen sclerosus: a marker for superimposed bullous pemphigoid?
    Histopathology, 2008, Volume: 52, Issue:7

    Topics: Aged; Azathioprine; Drug Therapy, Combination; Eosinophilia; Female; Glucocorticoids; Humans; Immuno

2008
[Azathioprine and its side effects].
    Zeitschrift fur Hautkrankheiten, 1984, Dec-01, Volume: 59, Issue:23

    Topics: Aged; Azathioprine; Gastrectomy; Hepatic Encephalopathy; Humans; Jaundice; Male; Methylprednisolone;

1984
Azathioprine for use in dermatology.
    The Journal of dermatologic surgery and oncology, 1984, Volume: 10, Issue:6

    Topics: Azathioprine; Behcet Syndrome; Humans; Pemphigoid, Bullous; Pemphigus; Pityriasis Rubra Pilaris; Pso

1984
[Psoriasis and pemphigoid (author's transl)].
    Dermatologica, 1981, Volume: 163, Issue:1

    Topics: Adult; Aged; Azathioprine; Female; Humans; Male; Methylprednisolone; Middle Aged; Pemphigoid, Bullou

1981
Immunosuppressive therapy for progressive ocular cicatricial pemphigoid.
    Ophthalmology, 1982, Volume: 89, Issue:4

    Topics: Adult; Aged; Azathioprine; Cicatrix; Conjunctival Diseases; Corneal Diseases; Cyclophosphamide; Drug

1982
Azathioprine-induced shock in dermatology patients.
    Journal of the American Academy of Dermatology, 1993, Volume: 29, Issue:5 Pt 1

    Topics: Aged; Anaphylaxis; Azathioprine; Female; Humans; Male; Middle Aged; Pemphigoid, Bullous; Polyarterit

1993
Azathioprine in dermatology: a survey of current practice in the U.K.
    The British journal of dermatology, 1997, Volume: 136, Issue:3

    Topics: Azathioprine; Bone Marrow; Dermatitis, Atopic; Dermatology; Drug Administration Schedule; Health Car

1997
Retroperitoneal round-cell liposarcoma associated with paraneoplastic pemphigus presenting as lichen planus pemphigoides-like eruption.
    International journal of dermatology, 1997, Volume: 36, Issue:7

    Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Azathioprine; Diagnosis, Differential; Fe

1997
Kaposi's sarcoma associated with immunosuppression for bullous pemphigoid.
    The British journal of dermatology, 1997, Volume: 137, Issue:1

    Topics: Aged; Aged, 80 and over; Azathioprine; Humans; Immunosuppressive Agents; Leg; Male; Pemphigoid, Bull

1997
Identification of HHV-8 DNA in the skin lesions of Kaposi's sarcoma in an immunosuppressed patient with bullous pemphigoid.
    Journal of the American Academy of Dermatology, 1997, Volume: 37, Issue:5 Pt 2

    Topics: Aged; Aged, 80 and over; Azathioprine; DNA, Viral; Female; Herpesvirus 8, Human; Humans; Immunosuppr

1997
Psoriasis and bullous pemphigoid treated with azathioprine.
    Journal of the American Academy of Dermatology, 1998, Volume: 39, Issue:1

    Topics: Aged; Aged, 80 and over; Azathioprine; Basement Membrane; Complement C3c; Female; Fluorescent Antibo

1998
Screening for azathioprine toxicity: a pharmacoeconomic analysis based on a target case.
    Journal of the American Academy of Dermatology, 2000, Volume: 42, Issue:4

    Topics: Adult; Azathioprine; Costs and Cost Analysis; Female; Genetic Testing; Homozygote; Humans; Immunosup

2000
Plasmapheresis as a steroid saving procedure in bullous pemphigoid.
    International journal of dermatology, 2000, Volume: 39, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Autoantigens; Azathioprine; Carrier Protei

2000
Pemphigoid: clinical, histologic, immunopathologic, and therapeutic considerations.
    JAMA, 2000, Jul-19, Volume: 284, Issue:3

    Topics: Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Basement Membrane; Female; Glucocortic

2000
Generalization of cicatricial pemphigoid during azathioprine therapy.
    Archives of dermatology, 2000, Volume: 136, Issue:10

    Topics: Aged; Azathioprine; Cicatrix; Female; Humans; Immunosuppressive Agents; Pemphigoid, Bullous

2000
[Polyradiculopathy associated with bullous pemphigoid (author's transl)].
    La Nouvelle presse medicale, 1979, Jan-27, Volume: 8, Issue:5

    Topics: Aged; Azathioprine; Dermatitis Herpetiformis; Diagnosis, Differential; Humans; Male; Pemphigoid, Bul

1979
[Plasma exchange therapy of dermatosis].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Betamethasone; Female; Humans; Middle Aged; Pemphigoid

1992
Lack of predictive factors for the clinical course of bullous pemphigoid.
    Journal of the American Academy of Dermatology, 1992, Volume: 26, Issue:4

    Topics: Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Dapsone; Drug Therapy, Combination; Fema

1992
[Genital mucous membrane manifestation of localized bullous pemphigoid].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1991, Volume: 42, Issue:3

    Topics: Aged; Azathioprine; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Humans; Immun

1991
Azathioprine hypersensitivity in bullous pemphigoid.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:1

    Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Fever; Headache; Humans; Pemphigoid, Bullous; Ski

1990
[Therapeutic use of plasmapheresis in a patient with bullous pemphigoid].
    Vestnik dermatologii i venerologii, 1989, Issue:2

    Topics: Aged; Aged, 80 and over; Azathioprine; Humans; Male; Pemphigoid, Bullous; Plasmapheresis; Skin Disea

1989
Anesthetic management of a patient with bullous pemphigoid.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:4

    Topics: Anesthesia, Spinal; Azathioprine; Female; Humans; Injections, Spinal; Middle Aged; Pemphigoid, Bullo

1989
Adjuvant therapy of bullous pemphigoid with dapsone.
    Clinical and experimental dermatology, 1989, Volume: 14, Issue:2

    Topics: Adult; Aged; Azathioprine; Dapsone; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pe

1989
The prodrome of bullous pemphigoid.
    International journal of dermatology, 1988, Volume: 27, Issue:8

    Topics: Aged; Azathioprine; Biopsy; Dermatitis; Female; Fluorescent Antibody Technique; Humans; Middle Aged;

1988
[Therapy of pemphigus and pemphigoid].
    Zeitschrift fur Hautkrankheiten, 1986, Jun-01, Volume: 61, Issue:11

    Topics: Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Humans; Methotrexate; Pemphigoid, Bullous

1986