azathioprine has been researched along with Pemphigoid, Benign Mucous Membrane in 24 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Pemphigoid, Benign Mucous Membrane: A chronic blistering disease with predilection for mucous membranes and less frequently the skin, and with a tendency to scarring. It is sometimes called ocular pemphigoid because of conjunctival mucous membrane involvement.
Excerpt | Relevance | Reference |
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"Azathioprine was moderately effective as a single corticosteroid-sparing immunosuppressive agent in terms of control of inflammation and corticosteroid-sparing benefits, but required several months to achieve treatment goals; it seems especially useful for patients with intermediate uveitis." | 3.75 | Azathioprine for ocular inflammatory diseases. ( Foster, CS; Jabs, DA; Kempen, JH; Levy-Clarke, GA; Liesegang, TL; Newcomb, CW; Nussenblatt, RB; Pasadhika, S; Pujari, SS; Rosenbaum, JT; Suhler, EB; Thorne, JE, 2009) |
"Ocular cicatricial pemphigoid (OCP) is a rare autoimmune disease with heterogenous clinical manifestations." | 1.51 | Ocular Cicatricial Pemphigoid: Camouflaged as Persistent Conjunctivitis. ( Erum, U; Mughal, JU; Muhammad, AJ, 2019) |
"Dapsone was useful in mild cases, with frequent adverse effects." | 1.38 | [Systemic treatment of ocular cicatricial pemphigoid]. ( Devoto, MH; Fernández Romero, DS; Georgiett, D; Juri, MC; Malbrán, A; Zárate, JO, 2012) |
"Dapsone was the most commonly used drug (51 patients), followed by methotrexate (24 patients), azathioprine (23 patients), and cyclophosphamide (15 patients); prednisone, always given as adjunctive treatment, was used in 17 patients." | 1.31 | The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid. ( Ahmed, AR; Baltatzis, S; Foster, CS; Miserocchi, E; Roque, MR, 2002) |
"Nine patients (11 eyes) with ocular cicatricial pemphigoid were treated with systemic azathioprine and a syngeneic nasal mucosa transplant from the inferior turbinate." | 1.29 | [Syngeneic transplantation of nasal mucosa and azathioprine medication for therapy of cicatricial ocular mucous membrane pemphigoid. Study of 9 patients with 11 eyes]. ( Bialasiewicz, AA; Busse, H; Förster, W; Grewe, S; Hüttenbrink, KB; Radig, H, 1994) |
"The diagnosis of cicatricial pemphigoid requires characteristic lesions and histopathologic evidence of immunoglobulin deposition along the basement membrane, as well as a high index of suspicion." | 1.29 | Management of airway obstruction in cicatricial pemphigoid. ( Goodman, ML; Lazor, JB; Mackool, BT; Montgomery, WW; Varvares, MA, 1996) |
"Ocular cicatricial pemphigoid (OCP) is a chronic, progressive, autoimmune disease that scars mucus membranes and may lead to blindness." | 1.28 | Remission and recurrence after withdrawal of therapy for ocular cicatricial pemphigoid. ( Foster, CS; Neumann, R; Tauber, J, 1991) |
"We found that untreated ocular cicatricial pemphigoid has a variable course and does not necessarily progress." | 1.27 | Immunosuppressive therapy in ocular cicatricial pemphigoid. ( Brown, SI; Mondino, BJ, 1983) |
"1." | 1.26 | [Disseminated cicatricial pemphigoid]. ( Braun-Falco, O; Ponce, E; Wolff, HH, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (12.50) | 18.7374 |
1990's | 7 (29.17) | 18.2507 |
2000's | 7 (29.17) | 29.6817 |
2010's | 5 (20.83) | 24.3611 |
2020's | 2 (8.33) | 2.80 |
Authors | Studies |
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Yaïci, R | 1 |
Roth, M | 1 |
Juergens, L | 1 |
Nawaiseh, SA | 1 |
Burkhard, D | 1 |
Besgen, V | 1 |
Fuest, M | 1 |
Girbardt, C | 1 |
Hampel, U | 1 |
Heichel, J | 1 |
Heiligenhaus, A | 1 |
Herwig-Carl, MC | 1 |
Kakkassery, V | 1 |
Kontopoulou, K | 1 |
Löffler, KU | 1 |
Maier, PC | 1 |
Nölle, B | 1 |
Pach, J | 1 |
Paul, S | 1 |
Pleyer, U | 1 |
Pöllmann, M | 1 |
Saeger, M | 1 |
Schmidt, E | 1 |
Siebelmann, S | 1 |
Sokolenko, E | 1 |
Strudel, L | 1 |
Stübiger, N | 1 |
Tarhan, M | 1 |
Theuersbacher, J | 1 |
van Oterendorp, C | 1 |
Walker, M | 1 |
Wiecha, C | 1 |
Wykrota, AA | 1 |
Geerling, G | 1 |
Smichowski, AM | 1 |
Caputo, VD | 1 |
Romeo, C | 1 |
Rivero, E | 1 |
Morales, NS | 1 |
Casado, G | 1 |
Mughal, JU | 1 |
Muhammad, AJ | 1 |
Erum, U | 1 |
Gaudio, PA | 1 |
Sinard, J | 1 |
Shield, DR | 1 |
Huang, JJ | 1 |
King, BA | 1 |
Liu, A | 1 |
Yang, DJ | 1 |
Hsu, S | 1 |
Tauber, J | 3 |
Pasadhika, S | 1 |
Kempen, JH | 1 |
Newcomb, CW | 1 |
Liesegang, TL | 1 |
Pujari, SS | 1 |
Rosenbaum, JT | 1 |
Thorne, JE | 1 |
Foster, CS | 4 |
Jabs, DA | 1 |
Levy-Clarke, GA | 1 |
Nussenblatt, RB | 1 |
Suhler, EB | 1 |
Kennedy, JS | 1 |
Devillez, RL | 1 |
Henning, JS | 1 |
McGinness, JL | 1 |
Spicknall, KE | 1 |
Mutasim, DF | 1 |
Juri, MC | 1 |
Fernández Romero, DS | 1 |
Devoto, MH | 1 |
Georgiett, D | 1 |
Zárate, JO | 1 |
Malbrán, A | 1 |
Saw, VP | 1 |
Dart, JK | 1 |
Rauz, S | 1 |
Ramsay, A | 1 |
Bunce, C | 1 |
Xing, W | 1 |
Maddison, PG | 1 |
Phillips, M | 1 |
Mondino, BJ | 1 |
Brown, SI | 1 |
Braun-Falco, O | 1 |
Wolff, HH | 1 |
Ponce, E | 1 |
Bialasiewicz, AA | 1 |
Förster, W | 1 |
Radig, H | 1 |
Hüttenbrink, KB | 1 |
Grewe, S | 1 |
Busse, H | 1 |
Warren, SD | 1 |
Lesher, JL | 1 |
Lazor, JB | 1 |
Varvares, MA | 1 |
Montgomery, WW | 1 |
Goodman, ML | 1 |
Mackool, BT | 1 |
Singer, NG | 1 |
McCune, WJ | 1 |
Messmer, EM | 1 |
Hintschich, CR | 1 |
Partscht, K | 1 |
Messer, G | 1 |
Kampik, A | 1 |
Epstein, JB | 1 |
Gorsky, M | 1 |
Epstein, MS | 1 |
Nantel, S | 1 |
Miserocchi, E | 1 |
Baltatzis, S | 1 |
Roque, MR | 1 |
Ahmed, AR | 1 |
Lamey, PJ | 1 |
Rees, TD | 1 |
Binnie, WH | 1 |
Rankin, KV | 1 |
Neumann, R | 1 |
Sainz de la Maza, M | 1 |
Pawlofsky, C | 1 |
Simon, M | 1 |
Fartasch, M | 1 |
Keller, J | 1 |
1 review available for azathioprine and Pemphigoid, Benign Mucous Membrane
Article | Year |
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Update on immunosuppressive therapy.
Topics: Adult; Arthritis, Juvenile; Azathioprine; Behcet Syndrome; Child; Cladribine; Cyclophosphamide; Cycl | 1998 |
23 other studies available for azathioprine and Pemphigoid, Benign Mucous Membrane
Article | Year |
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On the Current Care Situation and Treatment of Ocular Mucous Membrane Pemphigoid in Germany.
Topics: Azathioprine; Humans; Immunosuppressive Agents; Mucous Membrane; Pemphigoid, Benign Mucous Membrane; | 2023 |
Ocular cicatricial pemphigoid: Methotrexate as an initial treatment?
Topics: Azathioprine; Cyclophosphamide; Humans; Immunosuppressive Agents; Methotrexate; Pemphigoid, Benign M | 2022 |
Ocular Cicatricial Pemphigoid: Camouflaged as Persistent Conjunctivitis.
Topics: Autoimmune Diseases; Azathioprine; Conjunctiva; Conjunctivitis; Cornea; Corneal Perforation; Cycloph | 2019 |
Repeat Conjunctival Biopsy after Immunomodulatory Therapy for Ocular Mucous Membrane Pemphigoid.
Topics: Aged; Aged, 80 and over; Azathioprine; Biopsy; Conjunctiva; Conjunctival Diseases; Cyclophosphamide; | 2018 |
A quick and simple serum test to differentiate bullous pemphigoid, epidermolysis bullosa acquisita, and anti-epiligrin cicatricial pemphigoid.
Topics: Aged; Azathioprine; Cell Adhesion Molecules; Complement C3; Diagnosis, Differential; Drug Therapy, C | 2008 |
Ocular cicatricial pemphigoid.
Topics: Azathioprine; Conjunctival Diseases; Cyclophosphamide; Dapsone; Drug Therapy, Combination; Humans; I | 2008 |
Azathioprine for ocular inflammatory diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Female; Follow-Up Studies; Humans; | 2009 |
Recalcitrant cicatricial pemphigoid treated with the anti-TNF-alpha agent etanercept.
Topics: Administration, Topical; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathiop | 2010 |
Azathioprine-induced EBV-positive mucocutaneous ulcer.
Topics: Aged; Antigens, CD20; Antimetabolites, Antineoplastic; Azathioprine; B-Lymphocytes; Epstein-Barr Vir | 2012 |
[Systemic treatment of ocular cicatricial pemphigoid].
Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Dapsone; Delayed Diagnosis; Femal | 2012 |
Immunosuppressive therapy for ocular mucous membrane pemphigoid strategies and outcomes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Conjunctival Diseases; Cyclophosphamide; D | 2008 |
Immunosuppressive therapy in ocular cicatricial pemphigoid.
Topics: Aged; Azathioprine; Cyclophosphamide; Eye Diseases; Female; Humans; Immunosuppressive Agents; Male; | 1983 |
[Disseminated cicatricial pemphigoid].
Topics: Aged; Azathioprine; Basement Membrane; Complement C3; Humans; Immunoglobulin M; Male; Pemphigoid, Be | 1981 |
[Syngeneic transplantation of nasal mucosa and azathioprine medication for therapy of cicatricial ocular mucous membrane pemphigoid. Study of 9 patients with 11 eyes].
Topics: Aged; Aged, 80 and over; Azathioprine; Combined Modality Therapy; Conjunctivitis; Female; Follow-Up | 1994 |
Cicatricial pemphigoid.
Topics: Aged; Azathioprine; Dapsone; Fluorescent Antibody Technique; Humans; Male; Mouth Mucosa; Pemphigoid, | 1993 |
Management of airway obstruction in cicatricial pemphigoid.
Topics: Adult; Airway Obstruction; Anti-Inflammatory Agents; Azathioprine; Chronic Disease; Diagnosis, Diffe | 1996 |
[Ocular cicatricial pemphigoid. Retrospective analysis of risk factors and complications].
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Azathiopr | 2000 |
Topical azathioprine in the treatment of immune-mediated chronic oral inflammatory conditions: a series of cases.
Topics: Adult; Autoimmune Diseases; Azathioprine; Chronic Disease; Erythema; Female; Gels; Graft vs Host Dis | 2001 |
The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Azathi | 2002 |
Mucous membrane pemphigoid. Treatment experience at two institutions.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Cyclophosp | 1992 |
Remission and recurrence after withdrawal of therapy for ocular cicatricial pemphigoid.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Cyclophosphamide; Dapsone; Female; Follow-Up Studies; | 1991 |
Systemic chemotherapy for ocular cicatricial pemphigoid.
Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Conjunctivitis; Cyclophosphamide; | 1991 |
Disseminated cicatricial pemphigoid.
Topics: Azathioprine; Drug Therapy, Combination; Humans; Male; Middle Aged; Pemphigoid, Benign Mucous Membra | 1985 |