azathioprine has been researched along with Parkinson Disease in 5 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with prednisone and azathioprine did not give any improvement of the neurological symptoms." | 1.29 | Hemiparkinsonism in a patient with primary Sjögren's syndrome. A case report and a review of the literature. ( Koudstaal, PJ; van de Merwe, JP; Visser, LH, 1993) |
| "Two patients presented with a subacute confusional state, two with dementia, and one with depression." | 1.28 | Neuropsychiatric systemic lupus erythematosus in elderly people: a case series. ( Bendall, P; Byrne, EJ; Dennis, MS; Hopkinson, N, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greenland, JC | 1 |
| Cutting, E | 1 |
| Kadyan, S | 1 |
| Bond, S | 1 |
| Chhabra, A | 1 |
| Williams-Gray, CH | 1 |
| Kannoth, S | 1 |
| Anandakkuttan, A | 1 |
| Mathai, A | 1 |
| Sasikumar, AN | 1 |
| Nambiar, V | 1 |
| Levin, N | 1 |
| Karussis, D | 1 |
| Abramsky, O | 1 |
| Visser, LH | 1 |
| Koudstaal, PJ | 1 |
| van de Merwe, JP | 1 |
| Dennis, MS | 1 |
| Byrne, EJ | 1 |
| Hopkinson, N | 1 |
| Bendall, P | 1 |
1 trial available for azathioprine and Parkinson Disease
| Article | Year |
|---|---|
Azathioprine immunosuppression and disease modification in Parkinson's disease (AZA-PD): a randomised double-blind placebo-controlled phase II trial protocol.
Topics: Azathioprine; Double-Blind Method; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Park | 2020 |
4 other studies available for azathioprine and Parkinson Disease
| Article | Year |
|---|---|
Autoimmune atypical parkinsonism - A group of treatable parkinsonism.
Topics: Aged; Autoimmune Diseases; Azathioprine; Female; Glutamate Decarboxylase; Humans; Immunosuppressive | 2016 |
Parkinson's disease associated with myasthenia gravis. A report of 4 cases.
Topics: Aged; Azathioprine; Cholinesterase Inhibitors; Drug Therapy, Combination; Female; Humans; Immunosupp | 2003 |
Hemiparkinsonism in a patient with primary Sjögren's syndrome. A case report and a review of the literature.
Topics: Azathioprine; Brain; Corpus Striatum; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglob | 1993 |
Neuropsychiatric systemic lupus erythematosus in elderly people: a case series.
Topics: Aged; Aged, 80 and over; Azathioprine; Confusion; Dementia; Diagnosis, Differential; Drug Therapy, C | 1992 |