Page last updated: 2024-10-23

azathioprine and Paraparesis, Tropical Spastic

azathioprine has been researched along with Paraparesis, Tropical Spastic in 2 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Paraparesis, Tropical Spastic: A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakagawa, M1
Nakahara, K1
Maruyama, Y1
Kawabata, M1
Higuchi, I1
Kubota, H1
Izumo, S1
Arimura, K1
Osame, M2

Trials

1 trial available for azathioprine and Paraparesis, Tropical Spastic

ArticleYear
Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.
    Journal of neurovirology, 1996, Volume: 2, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory A

1996

Other Studies

1 other study available for azathioprine and Paraparesis, Tropical Spastic

ArticleYear
[HTLV-I-associated myelopathy].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Mar-10, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Female; HTLV-I Antibodies; Humans;

1992