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azathioprine and Paraneoplastic Syndromes

azathioprine has been researched along with Paraneoplastic Syndromes in 17 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Paraneoplastic Syndromes: In patients with neoplastic diseases a wide variety of clinical pictures which are indirect and usually remote effects produced by tumor cell metabolites or other products.

Research Excerpts

ExcerptRelevanceReference
"Dermatomyositis is a known paraneoplastic syndrome that can complicate the course of a variety of different cancers, however, the association with HCC is extremely rare."5.35Remission of paraneoplastic dermatomyositis associated with hepatocellular carcinoma under prednisolone and azathiopin, and concommittant sorafenib. ( Apostolidis, L; Horstmann, S; Jäger, D; Kahlert, C; Lordick, F; Siegmund, A; Thom, R, 2009)
"Dermatomyositis is characterized by marked clinical heterogeneity."2.43[The clinical spectrum of dermatomyositis]. ( Genth, E; Hunzelmann, N; Kaufmann, J; Krieg, T, 2005)
"Dermatomyositis is a known paraneoplastic syndrome that can complicate the course of a variety of different cancers, however, the association with HCC is extremely rare."1.35Remission of paraneoplastic dermatomyositis associated with hepatocellular carcinoma under prednisolone and azathiopin, and concommittant sorafenib. ( Apostolidis, L; Horstmann, S; Jäger, D; Kahlert, C; Lordick, F; Siegmund, A; Thom, R, 2009)
"The case of a patient with fatigable diplopia and ptosis 3 years after removal of a large-cell lung carcinoma is presented."1.31Myasthenia gravis with a paraneoplastic marker. ( Leavitt, JA, 2000)
"The conjunctiva later became scarred with foreshortening of the fornices and development of symblepharon."1.28Paraneoplastic pemphigus, cicatricial conjunctivitis, and acanthosis nigricans with pachydermatoglyphy in a patient with bronchogenic squamous cell carcinoma. ( Folberg, R; Goeken, JA; Krachmer, JH; Lam, S; Massicotte, SJ; Smith, AC; Stone, MS, 1992)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (41.18)18.2507
2000's8 (47.06)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Apostolidis, L1
Kahlert, C1
Siegmund, A1
Thom, R1
Horstmann, S1
Jäger, D1
Lordick, F1
Ferreyra, HA1
Jayasundera, T1
Khan, NW1
He, S1
Lu, Y1
Heckenlively, JR1
Dankó, K1
Vincze, M1
Frew, JW1
Murrell, DF1
Verrini, A1
Cannata, G1
Cozzani, E1
Terracini, M1
Parodi, A1
Rebora, A1
von Rainer Günther, ZB1
Nasser, S1
Hinrichsen, H1
Fölsch, UR1
Botsios, C1
Ostuni, P1
Boscolo-Rizzo, P1
Da Mosto, MC1
Punzi, L1
Marchiori, C1
Rossum, MM1
Verhaegen, NT1
Jonkman, MF2
Mackenzie, MA1
Koster, A1
Van Der Valk, PG1
Span, LF1
Kaufmann, J1
Hunzelmann, N1
Genth, E1
Krieg, T1
Plumb, R1
Doolittle, GC1
Schaller, M1
Korting, HC1
Meurer, M1
Schirren, CG1
Krunic, AL1
Kokai, D1
Bacetic, B1
Kesic, V1
Nikolic, MM1
Petkovic, S1
Clark, RE1
van der Waal, RI1
Pas, HH1
Anhalt, GJ1
Schulten, EA1
Nieboer, C1
van den Berg, JS1
van Engelen, BG1
Boerman, RH1
de Baets, MH1
Leavitt, JA1
Sieb, JP1
Dengler, R1
Jerusalem, F1
Lam, S1
Stone, MS1
Goeken, JA1
Massicotte, SJ1
Smith, AC1
Folberg, R1
Krachmer, JH1

Reviews

3 reviews available for azathioprine and Paraneoplastic Syndromes

ArticleYear
[New therapeutic approaches for polymyositis and dermatomyositis].
    Orvosi hetilap, 2011, Sep-25, Volume: 152, Issue:39

    Topics: Adrenal Cortex Hormones; Algorithms; Antineoplastic Agents; Azathioprine; Biological Therapy; Cell M

2011
Current management strategies in paraneoplastic pemphigus (paraneoplastic autoimmune multiorgan syndrome).
    Dermatologic clinics, 2011, Volume: 29, Issue:4

    Topics: Adrenal Cortex Hormones; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Mur

2011
[The clinical spectrum of dermatomyositis].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2005, Volume: 3, Issue:3

    Topics: Adult; Age Factors; Azathioprine; Biopsy; Child; Clinical Trials as Topic; Cyclophosphamide; Cyclosp

2005

Other Studies

14 other studies available for azathioprine and Paraneoplastic Syndromes

ArticleYear
Remission of paraneoplastic dermatomyositis associated with hepatocellular carcinoma under prednisolone and azathiopin, and concommittant sorafenib.
    Onkologie, 2009, Volume: 32, Issue:1-2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Benzenesulfonates; Carcinoma, Hepatoce

2009
Management of autoimmune retinopathies with immunosuppression.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2009, Volume: 127, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Autoimmune Diseases; Azath

2009
A patient with immunological features of paraneoplastic pemphigus in the absence of a detectable malignancy.
    Acta dermato-venereologica, 2002, Volume: 82, Issue:5

    Topics: Aged; Autoantibodies; Autoantigens; Azathioprine; Cytoskeletal Proteins; Desmoplakins; Disease Progr

2002
[Erythema gyratum repens. Drug hypersensitivity after azathioprine in a patient with type 1 autoimmune hepatitis].
    Medizinische Klinik (Munich, Germany : 1983), 2002, Dec-15, Volume: 97, Issue:12

    Topics: Azathioprine; Diagnosis, Differential; Drug Eruptions; Female; Hepatitis, Autoimmune; Humans; Immuno

2002
Dermatomyositis and malignancy of the pharynx in Caucasian patients: report of two observations.
    Rheumatology international, 2003, Volume: 23, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Carcinoma, Squamous Cell; Combin

2003
Follicular non-Hodgkin's lymphoma with refractory paraneoplastic pemphigus: case report with review of novel treatment modalities.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:11

    Topics: Adrenal Cortex Hormones; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antig

2004
Paraneoplastic pemphigus in a patient with non-Hodgkin's lymphoma.
    American journal of hematology, 1996, Volume: 52, Issue:1

    Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined Modality Thera

1996
[Generalized Mycobacterium avium-intracellulare infection due to immunosuppressive therapy of paraneoplastic dermatomyositis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1997, Volume: 48, Issue:2

    Topics: Adenocarcinoma; Azathioprine; Biopsy; Breast Neoplasms; Dermatomyositis; Female; Fluocortolone; Huma

1997
Retroperitoneal round-cell liposarcoma associated with paraneoplastic pemphigus presenting as lichen planus pemphigoides-like eruption.
    International journal of dermatology, 1997, Volume: 36, Issue:7

    Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Azathioprine; Diagnosis, Differential; Fe

1997
Paraneoplastic pemphigus as the presenting symptom of a lymphoma of the tongue.
    Oral oncology, 1998, Volume: 34, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Cyclop

1998
Acquired neuromyotonia: superiority of plasma exchange over high-dose intravenous human immunoglobulin.
    Journal of neurology, 1999, Volume: 246, Issue:7

    Topics: Anti-Inflammatory Agents; Azathioprine; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agen

1999
Myasthenia gravis with a paraneoplastic marker.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2000, Volume: 20, Issue:2

    Topics: Autoantibodies; Azathioprine; Biomarkers; Blepharoptosis; Calcium Channels; Carcinoma, Large Cell; D

2000
[Non-neoplastic Lambert-Eaton syndrome. A frequently missed diagnosis?].
    Der Nervenarzt, 1992, Volume: 63, Issue:4

    Topics: Adult; Azathioprine; Diagnosis, Differential; Electric Stimulation; Female; Humans; Lambert-Eaton My

1992
Paraneoplastic pemphigus, cicatricial conjunctivitis, and acanthosis nigricans with pachydermatoglyphy in a patient with bronchogenic squamous cell carcinoma.
    Ophthalmology, 1992, Volume: 99, Issue:1

    Topics: Acanthosis Nigricans; Aged; Azathioprine; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Chronic

1992