Page last updated: 2024-10-23

azathioprine and Panuveitis

azathioprine has been researched along with Panuveitis in 8 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Panuveitis: Inflammation in which both the anterior and posterior segments of the uvea are involved and a specific focus is not apparent. It is often severe and extensive and a serious threat to vision. Causes include systemic diseases such as tuberculosis, sarcoidosis, and syphilis, as well as malignancies. The intermediate segment of the eye is not involved.

Research Excerpts

ExcerptRelevanceReference
" Methotrexate is probably slightly more efficacious than mycophenolate in achieving control of inflammation, including steroid-sparing control (moderate-certainty evidence), although there was insufficient evidence to prefer one medication over the other in the VKH subgroup (very low-certainty evidence)."5.22Non-biologic, steroid-sparing therapies for non-infectious intermediate, posterior, and panuveitis in adults. ( Edwards Mayhew, RG; Leslie, L; Li, T; McCann, P; Palestine, AG; Strong Caldwell, A, 2022)
"Adamantiades-Behcet's disease (ABD) is a chronic recurrent vasculitis whose aetiology is still unclear."2.43[Adamantiades-Behcet's disease]. ( Krause, L, 2005)
"A 23-year-old-male patient with Behcet Disease had clinically inactive uveitis with topical steroids, oral azathiopurine and cyclosporine until he developed a retinal infiltrate in the left eye which evolved into a full-thickness macular hole during the follow-up."1.40An exceptional case of full-thickness macular hole closure in a patient with Behçet disease. ( Atalay, E; Özkök, A; Özyazgan, Y; Uçar, D; Yıldırım, Y, 2014)
"Prednisone was tapered after 1 month."1.40Success with single-agent immunosuppression for multifocal choroidopathies. ( Godbold, J; Goldberg, NR; Jabs, DA; Lyu, T; Moshier, E, 2014)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Edwards Mayhew, RG1
Li, T1
McCann, P1
Leslie, L1
Strong Caldwell, A1
Palestine, AG1
Tiew, S1
Uçar, D1
Atalay, E1
Özyazgan, Y1
Özkök, A1
Yıldırım, Y1
Goldberg, NR1
Lyu, T1
Moshier, E1
Godbold, J1
Jabs, DA1
Ramaiya, KJ1
Rao, PK1
Krause, L1
Gion, N1
Stavrou, P1
Foster, CS2
Michel, SS1
Ekong, A1
Baltatzis, S1

Reviews

2 reviews available for azathioprine and Panuveitis

ArticleYear
Non-biologic, steroid-sparing therapies for non-infectious intermediate, posterior, and panuveitis in adults.
    The Cochrane database of systematic reviews, 2022, 10-31, Volume: 10

    Topics: Adult; Antirheumatic Agents; Azathioprine; Cyclosporine; Humans; Immunosuppressive Agents; Inflammat

2022
[Adamantiades-Behcet's disease].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2005, Volume: 102, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Behcet Synd

2005

Other Studies

6 other studies available for azathioprine and Panuveitis

ArticleYear
Tattoo-associated panuveitis: A 10-year follow-up.
    European journal of ophthalmology, 2019, Volume: 29, Issue:1_suppl

    Topics: Azathioprine; Biopsy; Cataract Extraction; Epiretinal Membrane; Follow-Up Studies; Glucocorticoids;

2019
An exceptional case of full-thickness macular hole closure in a patient with Behçet disease.
    Ocular immunology and inflammation, 2014, Volume: 22, Issue:1

    Topics: Administration, Oral; Administration, Topical; Azathioprine; Behcet Syndrome; Cyclosporine; Drug The

2014
Success with single-agent immunosuppression for multifocal choroidopathies.
    American journal of ophthalmology, 2014, Volume: 158, Issue:6

    Topics: Adolescent; Adult; Aged; Azathioprine; Chorioretinitis; Choroiditis; Drug Therapy, Combination; Elec

2014
Herpetic necrotizing retinitis following flucinolone acetonide intravitreal implant.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:1

    Topics: Acyclovir; Antiviral Agents; Azathioprine; Cataract; Drug Implants; Eye Infections, Viral; Herpes Si

2011
Immunomodulatory therapy for chronic tubulointerstitial nephritis-associated uveitis.
    American journal of ophthalmology, 2000, Volume: 129, Issue:6

    Topics: Adolescent; Adult; Azathioprine; Chronic Disease; Cyclosporine; Female; Follow-Up Studies; Humans; I

2000
Multifocal choroiditis and panuveitis: immunomodulatory therapy.
    Ophthalmology, 2002, Volume: 109, Issue:2

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory

2002