azathioprine has been researched along with Pain in 26 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the MAINTAIN Nephritis Trial, azathioprine (AZA) and mycophenolate mofetil (MMF) were compared as maintenance immunosuppressive treatment of proliferative lupus nephritis (LN) after a short-course of intravenous cyclophosphamide." | 9.16 | Repeat kidney biopsies fail to detect differences between azathioprine and mycophenolate mofetil maintenance therapy for lupus nephritis: data from the MAINTAIN Nephritis Trial. ( Aydin, S; Cervera, R; Cosyns, JP; D'Cruz, D; Delahousse, M; Depresseux, G; Fiehn, C; Gilboe, IM; Guillevin, L; Houssiau, FA; Jadoul, M; Karras, A; le Guern, V; Petera, P; Quémeneur, T; Ravelingien, I; Remy, P; Stoenoiu, MS; Tektonidou, M; Vasconcelos, C, 2012) |
| "Sixty-five patients, 33 receiving azathioprine and 32 receiving penicillamine, took part in a one-year, single-blind external-observer trial designed to compare the efficacy and toxicity of these two drugs in the treatment of rheumatoid arthritis." | 9.04 | Azathioprine and penicillamine in treatment of rheumatoid arthritis: a controlled trial. ( Barnes, CG; Berger, LA; Berry, H; Durance, RA; Evans, S; Liyanage, SP, 1976) |
| "Azathioprine was considered responsible for these two adverse reactions (shock) as an allergen." | 5.31 | [Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine]. ( Kawano, F; Kiyokawa, T; Sanada, I; Tsukamoto, A, 2000) |
| "In the MAINTAIN Nephritis Trial, azathioprine (AZA) and mycophenolate mofetil (MMF) were compared as maintenance immunosuppressive treatment of proliferative lupus nephritis (LN) after a short-course of intravenous cyclophosphamide." | 5.16 | Repeat kidney biopsies fail to detect differences between azathioprine and mycophenolate mofetil maintenance therapy for lupus nephritis: data from the MAINTAIN Nephritis Trial. ( Aydin, S; Cervera, R; Cosyns, JP; D'Cruz, D; Delahousse, M; Depresseux, G; Fiehn, C; Gilboe, IM; Guillevin, L; Houssiau, FA; Jadoul, M; Karras, A; le Guern, V; Petera, P; Quémeneur, T; Ravelingien, I; Remy, P; Stoenoiu, MS; Tektonidou, M; Vasconcelos, C, 2012) |
| "Sixty-five patients, 33 receiving azathioprine and 32 receiving penicillamine, took part in a one-year, single-blind external-observer trial designed to compare the efficacy and toxicity of these two drugs in the treatment of rheumatoid arthritis." | 5.04 | Azathioprine and penicillamine in treatment of rheumatoid arthritis: a controlled trial. ( Barnes, CG; Berger, LA; Berry, H; Durance, RA; Evans, S; Liyanage, SP, 1976) |
| "The use of MMF is associated with slight increases in gastrointestinal adverse effects, some hematologic adverse events, and CMV infections compared with Aza." | 2.42 | Safety of mycophenolate mofetil versus azathioprine in renal transplantation: a systematic review. ( Li, H; Li, Y; Lu, Y; Wang, K; Wei, Q; Yang, Y; Zhang, H, 2004) |
| "Management of ankylosing spondylitis (AS) is challenged by the progressive nature of the disease." | 2.41 | Conventional treatments for ankylosing spondylitis. ( Brandt, J; Dijkmans, B; Dougados, M; Khan, M; Maksymowych, W; van der Linden, S, 2002) |
| "Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors." | 1.31 | Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002) |
| "Azathioprine was considered responsible for these two adverse reactions (shock) as an allergen." | 1.31 | [Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine]. ( Kawano, F; Kiyokawa, T; Sanada, I; Tsukamoto, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (42.31) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antunes, H | 1 |
| Patraquim, C | 1 |
| Baptista, V | 1 |
| Silva Monteiro, L | 1 |
| Maroz, N | 1 |
| Field, H | 1 |
| MacIver, H | 1 |
| Hordon, L | 1 |
| Osborne, SF | 1 |
| Sims, JL | 1 |
| Rosser, PM | 1 |
| Stoenoiu, MS | 1 |
| Aydin, S | 1 |
| Tektonidou, M | 1 |
| Ravelingien, I | 1 |
| le Guern, V | 1 |
| Fiehn, C | 1 |
| Remy, P | 1 |
| Delahousse, M | 1 |
| Petera, P | 1 |
| Quémeneur, T | 1 |
| Vasconcelos, C | 1 |
| D'Cruz, D | 1 |
| Gilboe, IM | 1 |
| Jadoul, M | 1 |
| Karras, A | 1 |
| Depresseux, G | 1 |
| Guillevin, L | 1 |
| Cervera, R | 1 |
| Cosyns, JP | 1 |
| Houssiau, FA | 1 |
| Prasad, R | 1 |
| De Silva, M | 1 |
| Dougados, M | 1 |
| Dijkmans, B | 1 |
| Khan, M | 1 |
| Maksymowych, W | 1 |
| van der Linden, S | 1 |
| Brandt, J | 1 |
| Mayo, JM | 1 |
| Colmenarejo, MB | 1 |
| Vaquerizo, PJ | 1 |
| Gutierrez, MV | 1 |
| Wang, K | 1 |
| Zhang, H | 1 |
| Li, Y | 1 |
| Wei, Q | 1 |
| Li, H | 1 |
| Yang, Y | 1 |
| Lu, Y | 1 |
| van der Heijde, DM | 1 |
| van 't Hof, M | 1 |
| van Riel, PL | 1 |
| van de Putte, LB | 1 |
| Solinger, AM | 1 |
| Hess, EV | 1 |
| D'Haens, G | 1 |
| Suenaert, P | 1 |
| Westhovens, R | 1 |
| Rutgeerts, P | 1 |
| Sanada, I | 1 |
| Kawano, F | 1 |
| Tsukamoto, A | 1 |
| Kiyokawa, T | 1 |
| Craner, MJ | 1 |
| Zajicek, JP | 1 |
| Airò, P | 1 |
| Antonioli, CM | 1 |
| Vianelli, M | 1 |
| Toniati, P | 1 |
| Berry, H | 1 |
| Liyanage, SP | 1 |
| Durance, RA | 1 |
| Barnes, CG | 1 |
| Berger, LA | 1 |
| Evans, S | 1 |
| McLeod, JG | 1 |
| Hargrave, JC | 1 |
| Gye, RS | 1 |
| Pollard, JD | 1 |
| Walsh, JC | 1 |
| Little, JM | 1 |
| Booth, GC | 1 |
| Bosch, FH | 1 |
| Meinders, AE | 1 |
| Bailey, RR | 1 |
| Armour, P | 1 |
| Tumen, HJ | 1 |
| Melam, H | 1 |
| Patterson, R | 1 |
| Papp, JP | 1 |
| Watson, DW | 1 |
| Bull, FE | 1 |
| Goligher, JC | 1 |
| de Dombal, FT | 1 |
| Burton, I | 1 |
| Mezzadra, G | 1 |
| Randazzo, SD | 1 |
| Mirone, A | 1 |
| Fausa, O | 1 |
| Gjone, E | 1 |
| Kleine, FD | 1 |
| Keitel, W | 1 |
| Franke, A | 1 |
3 reviews available for azathioprine and Pain
| Article | Year |
|---|---|
Conventional treatments for ankylosing spondylitis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Azathioprine; Dipho | 2002 |
Safety of mycophenolate mofetil versus azathioprine in renal transplantation: a systematic review.
Topics: Azathioprine; Cytomegalovirus Infections; Follow-Up Studies; Humans; Immunosuppressive Agents; Incid | 2004 |
Crohn's disease, with special reference to surgical management.
Topics: Abdomen; Anus Diseases; Azathioprine; Barium Sulfate; Colitis, Ulcerative; Crohn Disease; Diagnosis, | 1972 |
5 trials available for azathioprine and Pain
| Article | Year |
|---|---|
Repeat kidney biopsies fail to detect differences between azathioprine and mycophenolate mofetil maintenance therapy for lupus nephritis: data from the MAINTAIN Nephritis Trial.
Topics: Adolescent; Adult; Azathioprine; Biopsy; Female; Follow-Up Studies; Humans; Immunosuppressive Agents | 2012 |
Validity of single variables and indices to measure disease activity in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; C-Reactive Protein; Disabled Persons; Hemo | 1993 |
Anti-tumour necrosis factor treatment with infliximab in a case of giant cell arteritis resistant to steroid and immunosuppressive drugs.
Topics: Aged; Antibodies, Monoclonal; Antirheumatic Agents; Azathioprine; Drug Resistance; Drug Therapy, Com | 2002 |
Azathioprine and penicillamine in treatment of rheumatoid arthritis: a controlled trial.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; Clinical Trials as Topic; Fem | 1976 |
Azathioprine treatment in Crohn's disease.
Topics: Adolescent; Adult; Azathioprine; Body Weight; Clinical Trials as Topic; Crohn Disease; Diarrhea; Fem | 1974 |
18 other studies available for azathioprine and Pain
| Article | Year |
|---|---|
Oral manifestations of Crohn's disease.
Topics: Azathioprine; Cheilitis; Crohn Disease; Glucocorticoids; Humans; Male; Oral Ulcer; Pain; Prednisolon | 2015 |
Necrotizing crescentic glomerulonephritis related to sarcoidosis: a case report.
Topics: Adult; Azathioprine; Black or African American; Creatinine; Female; Foot Diseases; Glomerulonephriti | 2015 |
An unusual case of testicular pain.
Topics: Administration, Oral; Adult; Azathioprine; Diagnosis, Differential; Diuretics; Drug Therapy, Combina | 2009 |
Short-term use of Infliximab in a case of recalcitrant idiopathic orbital inflammatory disease.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Blepharoptosis; Drug Therapy, Combin | 2009 |
Osteoporosis with underlying connective tissue disease: an unusual case.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant | 2002 |
Hypersensitivity reaction to azathioprine in a patient with ulcerative colitis. Infrequent manifestations.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Diagnosis, Differential; Drug Hypersensitivity; Fever; Hum | 2004 |
Rheumatic diseases and AIDS--is the association real?
Topics: Acquired Immunodeficiency Syndrome; Adult; Azathioprine; Female; Humans; Male; Muscular Diseases; Pa | 1993 |
Severe knee pain as the single symptom of CMV infection in acute ulcerative colitis treated with cyclosporine.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Azathioprine; Colitis, Ulcerative; Cyclosporine; Cyt | 1998 |
[Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine].
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Hepatitis, Autoimmune; Humans; Immunosuppressive | 2000 |
Immunosuppressive treatments in MS--side effects from azathioprine.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Multiple Sclerosis; Nausea; P | 2001 |
Nerve grafting in leprosy.
Topics: Adolescent; Adult; Australia; Azathioprine; Child; Female; Humans; Immunosuppression Therapy; Lepros | 1975 |
[General malaise, high fever and arthralgia as a rare side effect of azathioprine].
Topics: Azathioprine; Drug Hypersensitivity; Fever; Glomerulonephritis; Humans; Joint Diseases; Male; Middle | 1985 |
Letter: Acute arthralgia after high-dose intravenous methylprednisolone.
Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Foreign-Body Reaction; Graft Rejection; Huma | 1974 |
The drug therapy of ulcerative colitis and of Crohn's disease.
Topics: Adrenocorticotropic Hormone; Atropine; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diarrhea; D | 1974 |
Periarteritis nodosa. A remission achieved with combined prednisone and azathioprine therapy.
Topics: Abdomen, Acute; Adolescent; Azathioprine; Eosinophilia; Humans; Male; Neuritis; Pain; Polyarteritis | 1971 |
[Therapeutic experience with azathioprine in psoriasis].
Topics: Adult; Aged; Azathioprine; Diarrhea; Female; Humans; Male; Middle Aged; Pain; Psoriasis | 1972 |
Azathioprine (Imurel) therapy in Crohn's disease.
Topics: Adrenal Cortex Hormones; Azathioprine; Crohn Disease; Diarrhea; Humans; Male; Pain | 1971 |
[Therapy with immunosuppressive agents in hepatology].
Topics: Azathioprine; Colitis; Headache; Hepatitis; Humans; Leukocytes; Liver Cirrhosis; Liver Diseases; Pai | 1969 |