azathioprine has been researched along with Osteonecrosis in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Osteonecrosis: Death of a bone or part of a bone, either atraumatic or posttraumatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have described a 60-year-old woman with polymyalgia rheumatica treated initially with prednisone but ultimately with azathioprine and cyclophosphamide." | 3.67 | Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation. ( Canter, HG; Manz, HJ; Melton, J, 1986) |
| " These studies provide a compelling case for a re-evaluation of the long-term use of glucocorticoids in SLE, focusing on minimizing glucocorticoid exposure as part of the strategy to improve long-term outcomes." | 2.55 | It hasn't gone away: the problem of glucocorticoid use in lupus remains. ( Apostolopoulos, D; Morand, EF, 2017) |
| "Osteoporosis, osteopenia, and osteonecrosis are common in renal transplant recipients." | 1.36 | Bone disease in renal transplantation and pleotropic effects of vitamin D therapy. ( Balal, M; Binokay, F; Demir, E; Erken, U; Kurt, C; Paydas, S; Sertdemir, Y; Sikgenc, MM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apostolopoulos, D | 1 |
| Morand, EF | 1 |
| Sikgenc, MM | 1 |
| Paydas, S | 1 |
| Balal, M | 1 |
| Demir, E | 1 |
| Kurt, C | 1 |
| Sertdemir, Y | 1 |
| Binokay, F | 1 |
| Erken, U | 1 |
| Dumler, F | 1 |
| Levin, NW | 1 |
| Szego, G | 1 |
| Vulpetti, AT | 1 |
| Preuss, LE | 1 |
| McGeown, MG | 1 |
| Douglas, JF | 1 |
| Brown, WA | 1 |
| Donaldson, RA | 1 |
| Kennedy, JA | 1 |
| Loughridge, WG | 1 |
| Mehta, S | 1 |
| Nelson, SD | 1 |
| Doherty, CC | 1 |
| Johnstone, R | 1 |
| Todd, G | 1 |
| Hill, CM | 1 |
| Goldberg, VM | 1 |
| Porter, BB | 1 |
| Lance, EM | 1 |
| Felchle, LM | 1 |
| McPhee, LA | 1 |
| Kerr, ME | 1 |
| Houston, DM | 1 |
| Tang, S | 1 |
| Chan, TM | 1 |
| Lui, SL | 1 |
| Li, FK | 1 |
| Lo, WK | 1 |
| Lai, KN | 1 |
| Manz, HJ | 1 |
| Canter, HG | 1 |
| Melton, J | 1 |
1 review available for azathioprine and Osteonecrosis
| Article | Year |
|---|---|
It hasn't gone away: the problem of glucocorticoid use in lupus remains.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Azathioprine; Cardiovascular Diseases; Cata | 2017 |
7 other studies available for azathioprine and Osteonecrosis
| Article | Year |
|---|---|
Bone disease in renal transplantation and pleotropic effects of vitamin D therapy.
Topics: Azathioprine; Bone Density; Bone Diseases; Bone Diseases, Metabolic; Creatinine; Female; Humans; Kid | 2010 |
Advantage of long-term alternate day steroid therapy in renal transplantation: a controlled study.
Topics: Adult; Azathioprine; Bacterial Infections; Cadaver; Graft Rejection; Humans; Kidney Failure, Chronic | 1980 |
Advantages of low dose steroid from the day after renal transplantation.
Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Cadaver; Child; Diabetes Mellitus; Gastrointe | 1980 |
Transplantation of the canine knee joint on a vascular pedicle. A preliminary study.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Cartilage, Articular; Disease Models, Animal; Dogs; Eva | 1980 |
Systemic lupus erythematosus and bone marrow necrosis in a dog.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis; Azathio | 1996 |
Risk factors for avascular bone necrosis after renal transplantation.
Topics: Adrenal Cortex Hormones; Adult; Age of Onset; Asian People; Azathioprine; China; Cyclosporine; Drug | 2000 |
Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation.
Topics: Azathioprine; Cranial Nerve Diseases; Cyclophosphamide; Drug Therapy, Combination; Female; Herpes Zo | 1986 |