azathioprine has been researched along with Optic Nerve Diseases in 5 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Optic neuropathy is a well-known ocular manifestation occurring in patients with systemic lupus erythematosus (SLE), and it remains one of the major causes of blindness in these patients." | 2.40 | Optic neuropathy in systemic lupus erythematosus and antiphospholipid syndrome (APS): clinical features, pathogenesis, review of the literature and proposed ophthalmological criteria for APS diagnosis. ( Balacco Gabrieli, C; Giorgi, D, 1999) |
| "Sarcoidosis is a multisystem disease of unknown aetiology with pulmonary involvement in most patients." | 1.48 | Atypical sarcoidosis-associated uveitis: diagnostic challenges. ( Cehajic Kapetanovic, J; Jones, NP; Steeples, LR, 2018) |
| "We report an unusual case of MCTD with recurrent optic neuropathy and transverse myelopathy suggestive of a relapsing-remitting demyelinating disorder." | 1.29 | Mixed connective tissue disease: recurrent episodes of optic neuropathy and transverse myelopathy. Successful treatment with plasmapheresis. ( Baum, K; Flechtner, KM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cehajic Kapetanovic, J | 1 |
| Jones, NP | 1 |
| Steeples, LR | 1 |
| Flechtner, KM | 1 |
| Baum, K | 1 |
| Giorgi, D | 1 |
| Balacco Gabrieli, C | 1 |
| Larner, AJ | 1 |
| Farmer, SF | 1 |
| Gelwan, MJ | 1 |
| Kellen, RI | 1 |
| Burde, RM | 1 |
| Kupersmith, MJ | 1 |
1 review available for azathioprine and Optic Nerve Diseases
| Article | Year |
|---|---|
Optic neuropathy in systemic lupus erythematosus and antiphospholipid syndrome (APS): clinical features, pathogenesis, review of the literature and proposed ophthalmological criteria for APS diagnosis.
Topics: Adult; Antibodies, Antinuclear; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Azathioprin | 1999 |
4 other studies available for azathioprine and Optic Nerve Diseases
| Article | Year |
|---|---|
Atypical sarcoidosis-associated uveitis: diagnostic challenges.
Topics: Adrenal Cortex Hormones; Azathioprine; Choroiditis; Diagnosis, Differential; Drug Administration Sch | 2018 |
Mixed connective tissue disease: recurrent episodes of optic neuropathy and transverse myelopathy. Successful treatment with plasmapheresis.
Topics: Adult; Azathioprine; Female; Humans; Magnetic Resonance Imaging; Mixed Connective Tissue Disease; My | 1994 |
Myelopathy following influenza vaccination in inflammatory CNS disorder treated with chronic immunosuppression.
Topics: Adult; Azathioprine; Brain; Brown-Sequard Syndrome; Cervical Vertebrae; Drug Interactions; Humans; I | 2000 |
Sarcoidosis of the anterior visual pathway: successes and failures.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Combined Modality Therapy; Craniotomy; Follow-Up Studi | 1988 |