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azathioprine and Nephritis, Interstitial

azathioprine has been researched along with Nephritis, Interstitial in 20 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Nephritis, Interstitial: Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.

Research Excerpts

ExcerptRelevanceReference
"We describe a patient with rheumatoid arthritis (RA) who developed hypersensitivity after 3 weeks of therapy with azathioprine with fever, jaundice and renal insufficiency."7.68Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity. ( Devogelaer, JP; Geubel, A; Meys, E; Nagant de Deuxchaisnes, C; Rahier, J, 1992)
"Her renal biopsy showed acute tubulointerstitial nephritis and no active glomerulonephritis."5.33Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis. ( Bir, K; Carette, S; Herzenberg, AM, 2006)
"We describe a patient with rheumatoid arthritis (RA) who developed hypersensitivity after 3 weeks of therapy with azathioprine with fever, jaundice and renal insufficiency."3.68Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity. ( Devogelaer, JP; Geubel, A; Meys, E; Nagant de Deuxchaisnes, C; Rahier, J, 1992)
"Sarcoidosis is rare in children."1.72Granulomatous nephritis: A rare presentation of juvenile-onset sarcoidosis. ( Chotalia, P; Pandya, S; Srivastava, P, 2022)
"Her renal biopsy showed acute tubulointerstitial nephritis and no active glomerulonephritis."1.33Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis. ( Bir, K; Carette, S; Herzenberg, AM, 2006)
"Ulcerative colitis is an inflammatory bowel disease with chronic diarrhea, rectal bleeding and characteristic histological findings."1.31Nephronophthisis and ulcerative colitis in siblings: a new association. ( Ala-Mello, S; Kääriäinen, H; Koskimies, O, 2001)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19909 (45.00)18.7374
1990's5 (25.00)18.2507
2000's4 (20.00)29.6817
2010's1 (5.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Chotalia, P1
Pandya, S1
Srivastava, P1
Ayoub, I1
Almaani, S1
Alvarado, A1
Parikh, SV1
Rovin, BH1
Bir, K1
Herzenberg, AM1
Carette, S1
Shin, JI1
Lee, JS1
Jeong, HJ1
Adams, DA1
Gordon, A1
Maxwell, MH1
McHenry, PM1
Allan, JG1
Rodger, RS1
Lever, RS1
Isoniemi, HM1
Ahonen, J1
Tikkanen, MJ1
von Willebrand, EO1
Krogerus, L1
Eklund, BH1
Höckerstedt, KV1
Salmela, KE1
Häyry, PJ1
Parnham, AP1
Dittmer, I1
Mathieson, PW1
McIver, A1
Dudley, C1
Gion, N1
Stavrou, P1
Foster, CS1
Ala-Mello, S1
Kääriäinen, H1
Koskimies, O1
Ludwig, H1
Schernthaner, G1
Maguad, RA1
Simporios, AS1
Meys, E1
Devogelaer, JP1
Geubel, A1
Rahier, J1
Nagant de Deuxchaisnes, C1
Thoenes, GH1
Umscheid, T1
Sitter, T1
Langer, KH1
Nichols, G1
Flanagan, B1
van der Sluys Veer, J1
Johnson, JW1
Hampers, CL1
Merrill, JP1
Lyons, H1
Pinn, VW1
Cortell, S1
Cohen, JJ1
Harrington, JT1
Scheitlin, W1
Brunner, F1
Rosenfeld, JB1
Levi, J1
de Vries, A1
Levy, M1
Alwall, N1
Halldorson, T1
Kjellstrand, CM1
Lindholm, T1
Ahlström, CG1
Hauschild, G1
Schöne, D1
Wässer, S1

Reviews

1 review available for azathioprine and Nephritis, Interstitial

ArticleYear
[The significance of immunologic mechanisms in the pathogenesis of renal diseases. 2. Immune complex nephritis, cell mediated reactions, pyelonephritis, therapeutic possibilities and conclusions].
    Medizinische Klinik, 1978, May-12, Volume: 73, Issue:19

    Topics: Adrenal Cortex Hormones; Anticoagulants; Antigen-Antibody Complex; Azathioprine; Complement System P

1978

Trials

1 trial available for azathioprine and Nephritis, Interstitial

ArticleYear
Long-term consequences of different immunosuppressive regimens for renal allografts.
    Transplantation, 1993, Volume: 55, Issue:3

    Topics: Adult; Azathioprine; Cyclosporine; Diabetes Mellitus; Drug Therapy, Combination; Female; Glomerular

1993

Other Studies

18 other studies available for azathioprine and Nephritis, Interstitial

ArticleYear
Granulomatous nephritis: A rare presentation of juvenile-onset sarcoidosis.
    Modern rheumatology case reports, 2022, Jan-07, Volume: 6, Issue:1

    Topics: Adolescent; Azathioprine; Child; Female; Humans; Mycophenolic Acid; Nephritis, Interstitial; Prednis

2022
Quiz Page February 2016: Acute Kidney Injury in a Patient With Granulomatosis With Polyangiitis Receiving Maintenance Immunosuppressive Therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 67, Issue:2

    Topics: Acute Kidney Injury; Azathioprine; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agent

2016
Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis.
    The Journal of rheumatology, 2006, Volume: 33, Issue:1

    Topics: Acute Disease; Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Female; Granulomatosis

2006
Azathioprine and tubulointerstitial nephritis in HSP.
    The Journal of rheumatology, 2006, Volume: 33, Issue:12

    Topics: Azathioprine; Child; Contraindications; Humans; IgA Vasculitis; Immunosuppressive Agents; Kidney; Ne

2006
Azathioprine treatment of immunological renal disease.
    JAMA, 1967, Feb-13, Volume: 199, Issue:7

    Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Cortisone; Female; Glomerulonephritis; Humans; Lupus

1967
Nephrotoxicity due to azathioprine.
    The British journal of dermatology, 1993, Volume: 128, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Azathioprine; Humans; Kidney; Male; Nephritis, Interstitial

1993
Acute allergic reactions associated with azathioprine.
    Lancet (London, England), 1996, Aug-24, Volume: 348, Issue:9026

    Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nephritis, Interstitia

1996
Immunomodulatory therapy for chronic tubulointerstitial nephritis-associated uveitis.
    American journal of ophthalmology, 2000, Volume: 129, Issue:6

    Topics: Adolescent; Adult; Azathioprine; Chronic Disease; Cyclosporine; Female; Follow-Up Studies; Humans; I

2000
Nephronophthisis and ulcerative colitis in siblings: a new association.
    Pediatric nephrology (Berlin, Germany), 2001, Volume: 16, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chronic Dise

2001
Kidney transplantation in Cebu.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Adult; Azathioprine; Cyclosporine; Family; Female; Follow-Up Studies; Glomerulonephritis; Humans; Ki

1992
Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity.
    The Journal of rheumatology, 1992, Volume: 19, Issue:5

    Topics: Acute Disease; Arthritis, Rheumatoid; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury;

1992
Cyclosporin A inhibits autoimmune experimental tubulointerstitial nephritis.
    Immunology letters, 1987, Volume: 15, Issue:4

    Topics: Animals; Autoantibodies; Autoimmune Diseases; Azathioprine; Basement Membrane; Cyclophosphamide; Cyc

1987
Metabolic studies of bone in uremia before and after treatment.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:4

    Topics: Adult; Azathioprine; Bone and Bones; Bone Resorption; Carbon Isotopes; Chronic Kidney Disease-Minera

1972
Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome.
    The New England journal of medicine, 1973, Jan-18, Volume: 288, Issue:3

    Topics: Acute Kidney Injury; Adult; Azathioprine; Chlorothiazide; Drug Hypersensitivity; Eosinophils; Female

1973
[Follow-up studies of Zurich clinical cases].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1967, Volume: 143, Issue:3

    Topics: Adult; Azathioprine; Cadaver; Chronic Disease; Follow-Up Studies; Glomerulonephritis; Hematologic Di

1967
Prolonged survival after kidney transplantation without the use of corticosteroids.
    Israel journal of medical sciences, 1971, Volume: 7, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Histocompatibility Testing; Humans; Immuno

1971
On corticosteroid and azathioprine treatment of glomerular renal diseases. A study of 90 cases, treated 1964-1969.
    Acta medica Scandinavica, 1972, Volume: 192, Issue:5

    Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Child; Collagen Diseases; Female; Glomerulonephritis;

1972
[Immunosuppressive therapy of glomerulotubular lesions in childhood].
    Zeitschrift fur Urologie und Nephrologie, 1970, Volume: 63, Issue:5

    Topics: Acute Disease; Azathioprine; Blood Cell Count; Blood Proteins; Blood Sedimentation; Child; Chronic D

1970