Page last updated: 2024-10-23

azathioprine and Necrosis

azathioprine has been researched along with Necrosis in 85 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Azathioprine is an immunosuppressant drug widely used."5.32Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine. ( Arriaza, E; Cara, C; Di Paola, M; Escribano, O; Fernández-Moreno, MD; Fueyo, JA; Guijarro, LG; Lorusso, M; Menor, C; Olleros, T; Román, ID, 2004)
" To avoid this potential interaction we treated recipients of primary cadaveric grafts initially with azathioprine (AZA), methylprednisolone (MP), and 5 daily doses of Minnesota antilymphoblast globulin (MAG) (postoperative days 3-7)."5.05Sequential use of Minnesota antilymphoblast globulin and cyclosporine in cadaveric renal transplantation. ( Dienst, S; Kupin, WL; Levin, NW; Oh, HK; Venkatachalam, KK, 1985)
" Despite intensive therapies including corticosteroids and azathioprine, marked progression of the ulcers was noted and large areas of necrosis appeared."3.78[Cutaneous polyarteritis nodosa--is it really benign?]. ( Berman, E; Halevy, S; Horev, A; Shavit, E, 2012)
"Therapeutic doses of methylprednisolone, azathioprine, cyclosporin A, and cyclophosphamide administered to mdx mice between 15 and 45 days of age failed to significantly influence the time course and prevalence of necrosis and regeneration or serum creatine kinase activity."3.68Glucocorticoids and immunosuppressants do not change the prevalence of necrosis and regeneration in mdx skeletal muscles. ( Carpenter, S; Karpati, G; Massa, R; Weller, B, 1991)
"A woman, aged 58, who had undergone prolonged treatment with corticosteroids for generalized necrotizing vasculitis, and had received azathioprine (Imurel) for 18 months, 4 years after discontinuing the latter treatment, developed peripheral neuropathy and a rapidly progressing cerebral disorder suggesting a basal meningeal process."3.66Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression. ( Jellinger, K; Kothbauer, P; Sunder-Plassmann, E; Weiss, R, 1979)
"In addition, Behcet's syndrome appears to be more common than previously assumed and is likely more common than a combination of ANCA-associated vasculitis (AAV) syndromes."2.45Necrotizing vasculitis--a 2009 update. ( Sharaf, PH; Yazici, Y, 2009)
"Idiopathic granulomatous mastitis is an inflammatory mass in the breast."1.37A case of granulomatous mastitis with erythema nodosum and arthritis. ( Karimifar, M; Mahzouni, P; Salesi, M; Salimi, F, 2011)
"Treatment with prednisone and azathioprine resulted in a dramatically improved outcome."1.36De novo autoimmune hepatitis with centrilobular necrosis following liver transplantation for primary biliary cirrhosis: a case report. ( Wang, B; Wang, T; Zhang, Y, 2010)
"Thoracic actinomycosis is a suppurative infection which can be difficult to diagnose as its presentation may mimic cancer or tuberculosis."1.35[Thoracic chest wall fistula formation]. ( Ayadi-Kaddour, A; Braham, E; El Mezni, F; Kilani, T; Marghli, A; Mlika, M, 2008)
"Azathioprine is an immunosuppressant drug widely used."1.32Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine. ( Arriaza, E; Cara, C; Di Paola, M; Escribano, O; Fernández-Moreno, MD; Fueyo, JA; Guijarro, LG; Lorusso, M; Menor, C; Olleros, T; Román, ID, 2004)
"Acute pancreatitis was induced in rats by using a combination of low-dose controlled intraductal glycodeoxycholic acid superimposed on intravenous cerulein hyperstimulation."1.30Effect of different immunosuppressive agents on acute pancreatitis: a comparative study in an improved animal model. ( Buhr, HJ; Foitzik, T; Forgacs, B; Gebhardt, MM; Hotz, H; Klar, E; Ryschich, E, 1998)
"We conclude that chronic ulcerative colitis can coexist with severe autoimmune hepatitis in the absence of primary sclerosing cholangitis or hepatitis C infection."1.28Frequency and significance of chronic ulcerative colitis in severe corticosteroid-treated autoimmune hepatitis. ( Carpenter, HA; Czaja, AJ; Perdigoto, R, 1992)
"Primary biliary cirrhosis is characterized by chronic inflammation and necrosis of the intrahepatic bile ducts and by chronic cholestasis."1.27NIH conference: Primary biliary cirrhosis: a model autoimmune disease. ( Hoofnagle, JH; James, SP; Jones, EA; Strober, W, 1983)
"The pancreatitis was first manifested by panniculitis of the lower extremities."1.27Childhood systemic lupus erythematosus. Association with pancreatitis, subcutaneous fat necrosis, and calcinosis cutis. ( Gorman, H; Penneys, N; Schachner, L; Simons-Ling, N; Strauss, J; Zillereulo, G, 1983)
"No patient showed recurrence of disease during treatment with cytotoxic agents."1.26Cyclophosphamide therapy of severe systemic necrotizing vasculitis. ( Fauci, AS; Haynes, BF; Katz, P; Wolff, SM, 1979)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199047 (55.29)18.7374
1990's21 (24.71)18.2507
2000's7 (8.24)29.6817
2010's8 (9.41)24.3611
2020's2 (2.35)2.80

Authors

AuthorsStudies
Biancardi, AL1
Costa, JB1
de Azevedo, LGB1
de Moraes, HV1
Barroso, PF1
Zaltman, C1
Dhanjal, S1
Saso, A1
Eleftheriou, D1
Laurent, S1
Taşkıran, EZ1
Sönmez, HE1
Ayvaz, DÇ1
Koşukcu, C1
Batu, ED1
Esenboğa, S1
Topaloğlu, R1
Orhan, D1
Bilginer, Y1
Alikaşifoğlu, M1
Özen, S1
Tezcan, İ1
Hasan, S1
Abushahin, A1
Prayson, R1
Kilani, A1
Ong, SG1
Ding, HJ1
Papadopoulou, D1
Valsamidis, K1
Kamargiannis, N1
Paricaud, K1
Pugnet, G1
Moulis, G1
Arlet, P1
Astudillo, L1
Sailler, L1
Otto, F1
Neuen-Jacob, E1
Arendt, G1
Stüve, O1
Hartung, HP1
Sharaf, PH1
Yazici, Y1
Salesi, M1
Karimifar, M1
Salimi, F1
Mahzouni, P1
Zhang, Y1
Wang, B1
Wang, T1
Shavit, E1
Horev, A1
Berman, E1
Halevy, S1
Tsanadis, GD1
Chouliara, ST1
Voulgari, PV1
Makrydimas, GV1
Drosos, AA1
BICKS, RO1
BROWN, G1
HICKEY, HD1
ROSENBERG, EW1
PORTER, KA2
MARCHIORO, TL1
STARZL, TE3
STRAFFON, RA1
NAKAMOTO, S1
KOLFF, WJ1
Houtman, PM1
Tapner, MJ1
Jones, BE1
Wu, WM1
Farrell, GC1
Menor, C1
Fernández-Moreno, MD1
Fueyo, JA1
Escribano, O1
Olleros, T1
Arriaza, E1
Cara, C1
Lorusso, M1
Di Paola, M1
Román, ID1
Guijarro, LG1
Ayadi-Kaddour, A1
Mlika, M1
Marghli, A1
Braham, E1
Kilani, T1
El Mezni, F1
James, SP1
Hoofnagle, JH1
Strober, W1
Jones, EA1
Häyry, P2
Ahonen, J1
von Willebrand, E2
Eklund, B1
Höckekstedt, K1
Kauste, A1
Taskinen, E3
Lautenschlager, I1
Lalla, M1
Sarelin, H1
Simons-Ling, N1
Schachner, L1
Penneys, N1
Gorman, H1
Zillereulo, G1
Strauss, J1
Lamberty, BG1
Goldberg, VM1
Porter, BB1
Lance, EM1
Bühler-Singer, S1
von Hintzenstern, J1
Fartasch, M1
Hornstein, OP1
Morozumi, K1
Takeda, A1
Uchida, K1
Oda, A1
Oikawa, T1
Sugito, K1
Kodera, K1
Fujinami, T1
Tominaga, Y1
Yoshida, A1
Bocchi, EA1
Bellotti, G1
Uip, D1
Kalil, J1
de Lourdes Higuchi, M1
Fiorelli, A1
Stolf, N1
Jatene, A1
Pilleggi, F1
Te, HS1
Koukoulis, G1
Ganger, DR1
Salminen, US2
Uusitalo, M1
Ikonen, T2
Morris, RE1
Harjula, AL2
Foitzik, T1
Forgacs, B1
Ryschich, E1
Hotz, H1
Gebhardt, MM1
Buhr, HJ1
Klar, E1
Alho, H1
Maasilta, P1
Fauci, AS1
Katz, P1
Haynes, BF1
Wolff, SM1
Zweiman, B1
Jellinger, K1
Kothbauer, P1
Weiss, R1
Sunder-Plassmann, E1
Demling, RH1
Salvatierra, O1
Belzer, FO2
Dewar, CL1
Bellamy, N1
Guerra, EE1
Didoné, EC1
Zanotelli, ML1
Vitola, SP1
Cantisani, GP1
Goldani, JC1
Keitel, E1
Garcia, VD1
Perdigoto, R1
Carpenter, HA1
Czaja, AJ1
Almirall, J1
Sole, M1
Campistol, JM1
Muntane, J1
Bru, C1
Oppenheimer, F1
Andreu, J1
Revert, L1
Reggiani, P1
Gatti, S1
Colledan, M1
Gridelli, B1
Maggi, U1
Rossi, G1
Caccamo, L1
Lucianetti, A1
Paone, G1
Piazzini Albani, A1
Ryba, M1
Iwańska, K1
Walski, M1
Pastuszko, M1
Cames, B1
Rahier, J1
Burtomboy, G1
de Ville de Goyet, J1
Reding, R1
Lamy, M1
Otte, JB2
Sokal, EM1
Podymova, SD1
Cotorruelo, JG1
De Francisco, AL1
Canga, E1
Amado, JA1
Riancho, JA1
De Bonis, E1
Zubimendi, JA1
Ruiz, JC1
Sanz de Castro, S1
Arias, M1
Weller, B1
Massa, R1
Karpati, G1
Carpenter, S1
Bohman, SO1
Wilczek, HE1
Reinholt, FP1
Brichard, B1
Sokal, E1
Gosseye, S1
Buts, JP1
Gadisseux, JF1
Cornu, G1
Diliz-Pérez, H1
Alvarez, L1
Zúñiga, V1
Estefan, J1
Mares, J1
Cerda, L1
Luque, E1
Carrera, B1
Volkow, P1
Martínez, R1
Brady, HR1
Kamel, KS1
Harding, ME1
Cook, GT1
deVeber, GA1
Cardella, CJ1
Bakran, A1
Johnson, RW1
Dyer, PA1
Mallick, NP1
Gokal, R1
Soper, WD1
Bergman, T1
Harward, T1
Huang, C1
Peterson, L1
Wolf, JS1
Ringe, B1
Oldhafer, K1
Bunzendahl, H1
Bechstein, WO1
Kotzerke, J1
Pichlmayr, R1
Shaunak, S1
Munro, JM1
Weinbren, K1
Walport, MJ1
Cox, TM1
Yagisawa, T1
Takahashi, K1
Teraoka, S1
Toma, H1
Agishi, T1
Ota, K1
Chavers, BM1
Nevins, TE1
Knaack, M1
Melvin, T1
Mauer, SM1
Paramasivan, ON1
Griffin, PJ1
Ross, WB1
Salaman, JR1
Triolo, G1
Segoloni, GP1
Ferrero, R1
Maritano, M1
Vercellone, A1
Cooper, C1
Cotton, DW1
Minihane, N1
Cawley, MI1
Kupin, WL1
Venkatachalam, KK1
Oh, HK1
Dienst, S1
Levin, NW1
Trivedi, P1
Cheeseman, P1
Portmann, B1
Hegarty, J1
Mowat, AP1
Troch, R1
Rombouts, JJ1
Vincent, A1
Alexandre, GP1
Friedman, A1
Kincaid-Smith, P1
Claman, HN1
Karr, RM1
Kohler, PF1
Mass, MF1
McIntosh, RM1
Sams, WM1
Small, P1
Stanford, RE1
Thorne, EG1
Brettschneider, L2
Penn, I2
Bell, P2
Putnam, CW2
McGuire, RL1
Gütgemann, A1
Schriefers, KH1
Esser, G1
Lee, TS1
Paquet, KJ1
Käufer, C1
Groth, CG1
Blanchard, H1
Kashiwagi, N1
Kaplan, D1
Ginzler, E1
Schweitzer, RT1
Holliday, M1
Kountz, SL1
Francon, F1
Diaz, R1
Lambotte, L1
Squifflet, JP1
Moriau, M1
Kestens, PJ1
Lesesne, HR1
Fallon, HJ1
Freiberger, Z1
Anuras, S1
Koff, RS1
Bonney, WW1
Carpenter, EW1
Lindenauer, SM1
Bergstein, JM1
Wiens, C1
Fish, AJ1
Vernier, RL1
Michael, A1
Leandri, J1
Lower, RR2
Kosek, JC2
Kemp, VE1
Graham, WH1
Sewell, DH2
Lim, F1
Beaudoin, JG1
Slapak, M1
Phillips, MJ1
Chandrasekaran, AK1
MacLean, LD1
Gondos, B1
White, P1
Benfield, JR1
Aichroth, P1
Branfoot, AC1
Huskisson, EC1
Loughridge, LW1
Leedham, PW1
Baum, M1
Cullum, PA1
Hurley, EJ1
Caravati, CM1
Hooker, TH1
Mistilis, SP1
Prince, HN1
Grunberg, E1

Reviews

4 reviews available for azathioprine and Necrosis

ArticleYear
Necrotizing vasculitis--a 2009 update.
    Bulletin of the NYU hospital for joint diseases, 2009, Volume: 67, Issue:3

    Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Azathioprine; Behcet Syndrome; Churg-Str

2009
[Problem of chronic hepatitis (classification, pathogenesis and treatment].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:6

    Topics: Autoimmune Diseases; Azathioprine; Chronic Disease; Hepatitis; Hepatitis B; Hepatitis B Antibodies;

1991
Cyclophosphamide-induced liver necrosis: a possible interaction with azathioprine.
    The Quarterly journal of medicine, 1988, Volume: 67, Issue:252

    Topics: Adult; Azathioprine; Cyclophosphamide; Drug Interactions; Female; Humans; Liver; Macrophages; Male;

1988
Treatment of liver disease with corticosteroids.
    The Medical clinics of North America, 1973, Volume: 57, Issue:5

    Topics: Adrenal Cortex Hormones; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Glucocort

1973

Trials

7 trials available for azathioprine and Necrosis

ArticleYear
Effect of cyclosporin A on the situ inflammatory response of human renal allograft rejection. A preliminary report.
    Scandinavian journal of immunology, 1982, Volume: 16, Issue:2

    Topics: Animals; Azathioprine; Clinical Trials as Topic; Creatinine; Cyclosporins; Eosinophilia; Follow-Up S

1982
Clinical usefulness of conventional fine needle aspiration cytology in kidney transplantation--influence of different immunosuppressive protocols.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Antilymphocyte Serum; Azathioprine; Cyclosporine; Humans; Immunosuppression Therapy; Kidney Transpla

1992
The influence of immunosuppression on the prevalence of aseptic bone necrosis after renal transplantation.
    Transplantation proceedings, 1991, Volume: 23, Issue:4

    Topics: Adult; Azathioprine; Bone and Bones; Cyclosporins; Female; Follow-Up Studies; Graft Rejection; Human

1991
Triple drug therapy in haploidentical living related and cadaveric kidney transplantation.
    Transplantation proceedings, 1991, Volume: 23, Issue:2

    Topics: Azathioprine; Cadaver; Cyclosporins; Drug Therapy, Combination; Family; Follow-Up Studies; Graft Rej

1991
Low dose ciclosporin from the early postoperative period yields potent immunosuppression after renal transplantation.
    Nephron, 1990, Volume: 55, Issue:4

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Cyclosporins; Dose-Response Rel

1990
Triple therapy improves the survival of cadaver renal allografts affected by acute tubular necrosis.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Adult; Azathioprine; Cadaver; Clinical Trials as Topic; Cyclosporins; Drug Therapy, Combination; Fem

1989
Sequential use of Minnesota antilymphoblast globulin and cyclosporine in cadaveric renal transplantation.
    Transplantation, 1985, Volume: 40, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Antilymphocyte Serum; Azathioprine; Cadaver; Clinical Trials

1985

Other Studies

74 other studies available for azathioprine and Necrosis

ArticleYear
Severe Necrotising Toxoplasmic Retinochoroiditis in a Patient With Crohn's Disease in Use of Adalimumab and Azathioprine.
    Inflammatory bowel diseases, 2020, 06-18, Volume: 26, Issue:7

    Topics: Adalimumab; Adult; Azathioprine; Chorioretinitis; Choroid; Crohn Disease; Female; Humans; Immunosupp

2020
Necrotic cutaneous vasculitic skin lesions: a case of atypical Henoch-Schönlein purpura in a child with heterozygosity for factor V Leiden.
    BMJ case reports, 2017, May-22, Volume: 2017

    Topics: Aspirin; Azathioprine; Biopsy; Child, Preschool; Factor V; Humans; IgA Vasculitis; Immunosuppressive

2017
Hypomorphic RAG1 defect in a child presented with pulmonary hemorrhage and digital necrosis.
    Clinical immunology (Orlando, Fla.), 2018, Volume: 187

    Topics: Anemia, Hemolytic; Azathioprine; Child, Preschool; Consanguinity; Cyclophosphamide; Diagnostic Error

2018
When Statins Cause an Autoimmune Response: A Report of a Severe Case of Rhabdomyolysis.
    The American journal of medicine, 2020, Volume: 133, Issue:1

    Topics: Aged; Atorvastatin; Autoantibodies; Autoimmune Diseases; Azathioprine; Creatine Kinase; Humans; Hydr

2020
Patient with statin-associated immune-mediated necrotizing myopathy presenting with subcutaneous edema, persistent bulbar weakness and absent anti-HMGCR.
    International journal of rheumatic diseases, 2017, Volume: 20, Issue:12

    Topics: Aged; Autoantibodies; Azathioprine; Biopsy; Bulbar Palsy, Progressive; Edema; Glucocorticoids; Human

2017
Endoscopy Dyspnea and Ulcerative Colitis.
    JAMA otolaryngology-- head & neck surgery, 2016, 12-01, Volume: 142, Issue:12

    Topics: Azathioprine; Colitis, Ulcerative; Dyspnea; Epiglottitis; Female; Humans; Immunocompromised Host; Im

2016
Digital necrosis revealing localized polyarteritis nodosa.
    Scandinavian journal of rheumatology, 2017, Volume: 46, Issue:6

    Topics: Aged; Angiography; Azathioprine; Cyclophosphamide; Female; Fingers; Humans; Immunosuppressive Agents

2017
A 69-year-old man with left hemispheric necrotizing mass lesion.
    Brain pathology (Zurich, Switzerland), 2009, Volume: 19, Issue:3

    Topics: Aged; Azathioprine; Brain; Brain Stem; Encephalitis, Viral; Epstein-Barr Virus Infections; Humans; I

2009
A case of granulomatous mastitis with erythema nodosum and arthritis.
    Rheumatology international, 2011, Volume: 31, Issue:8

    Topics: Antirheumatic Agents; Arthritis; Azathioprine; Colchicine; Drug Therapy, Combination; Erythema Nodos

2011
De novo autoimmune hepatitis with centrilobular necrosis following liver transplantation for primary biliary cirrhosis: a case report.
    Transplantation proceedings, 2010, Volume: 42, Issue:9

    Topics: Azathioprine; Biopsy; Drug Therapy, Combination; Female; Glucocorticoids; Hepatitis, Autoimmune; Hum

2010
[Cutaneous polyarteritis nodosa--is it really benign?].
    Harefuah, 2012, Volume: 151, Issue:10

    Topics: Amputation, Surgical; Arteries; Azathioprine; Biopsy; Disease Progression; Fatal Outcome; Female; Fl

2012
Outcome of pregnancy in a patient with relapsing polychondritis and pyoderma gangrenosum.
    Clinical rheumatology, 2002, Volume: 21, Issue:6

    Topics: Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Methylprednisolone; Necrosis; Polycho

2002
FURTHER OBSERVATIONS ON A DELAYED HYPERSENSITIVITY REACTION IN THE GUINEA PIG COLON.
    Gastroenterology, 1965, Volume: 48

    Topics: Allergens; Allergy and Immunology; Animals; Azathioprine; Colon; Guinea Pigs; Hypersensitivity; Hype

1965
PATHOLOGICAL CHANGES IN SIX TREATED BABOON-TO-MAN RENAL HETEROTRANSPLANTS.
    British journal of urology, 1965, Volume: 37

    Topics: Adolescent; Animals; Azathioprine; Haplorhini; Humans; Kidney; Kidney Transplantation; Male; Necrosi

1965
CLINICAL EXPERIENCE WITH RENAL TRANSPLANTATION.
    British journal of urology, 1965, Volume: 37

    Topics: Azathioprine; Cadaver; Dactinomycin; Drug Therapy; Hemorrhage; Humans; Hypertension; Immunosuppressi

1965
[Diagnostic image (176). A man with a black thumb. Necrosis of the thumb as a symptom of rheumatoid vasculitis].
    Nederlands tijdschrift voor geneeskunde, 2004, Feb-14, Volume: 148, Issue:7

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Humans; Male; Necrosis; Prednisone;

2004
Toxicity of low dose azathioprine and 6-mercaptopurine in rat hepatocytes. Roles of xanthine oxidase and mitochondrial injury.
    Journal of hepatology, 2004, Volume: 40, Issue:3

    Topics: Adenosine Triphosphate; Allopurinol; Animals; Antioxidants; Azathioprine; Cell Differentiation; Cell

2004
Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acetylcysteine; Animals; Apoptosis; Azathioprine; Caspase 3; Caspases; Cell Survival; Cytochromes c;

2004
[Thoracic chest wall fistula formation].
    Medecine et maladies infectieuses, 2008, Volume: 38, Issue:4

    Topics: Actinomycosis; Adult; Azathioprine; Cutaneous Fistula; Doxycycline; Humans; Lung Diseases, Fungal; M

2008
NIH conference: Primary biliary cirrhosis: a model autoimmune disease.
    Annals of internal medicine, 1983, Volume: 99, Issue:4

    Topics: Antibody Formation; Autoimmune Diseases; Azathioprine; Bile Ducts, Intrahepatic; Cholestasis; Humans

1983
Childhood systemic lupus erythematosus. Association with pancreatitis, subcutaneous fat necrosis, and calcinosis cutis.
    Archives of dermatology, 1983, Volume: 119, Issue:6

    Topics: Adipose Tissue; Azathioprine; Calcinosis; Child; Female; Humans; Hydrochlorothiazide; Lupus Erythema

1983
Pyoderma gangrenosum: report of an unusual case and a review of the literature.
    The Journal of dermatologic surgery and oncology, 1981, Volume: 7, Issue:1

    Topics: Azathioprine; Female; Humans; Leg Ulcer; Middle Aged; Necrosis; Prednisolone; Pyoderma; Skin; Staphy

1981
Transplantation of the canine knee joint on a vascular pedicle. A preliminary study.
    The Journal of bone and joint surgery. American volume, 1980, Volume: 62, Issue:3

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Cartilage, Articular; Disease Models, Animal; Dogs; Eva

1980
[Anticardiolipin syndrome with only skin involvement].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1994, Volume: 45, Issue:6

    Topics: Adult; Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Arm; Aspirin; Azathioprine; Combined

1994
Is a late graft biopsy at 3 years after transplantation effective for improving the long-term outcome of renal allografts using cyclosporine?
    Transplantation proceedings, 1994, Volume: 26, Issue:2

    Topics: Azathioprine; Biopsy; Cyclosporine; Drug Therapy, Combination; Endothelium, Vascular; Follow-Up Stud

1994
Long-term follow-up after heart transplantation in Chagas' disease.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Actuarial Analysis; Adrenal Cortex Hormones; Adult; Azathioprine; Chagas Cardiomyopathy; Chagas Dise

1993
Autoimmune hepatitis: a histological variant associated with prominent centrilobular necrosis.
    Gut, 1997, Volume: 41, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Autoimmune Diseases; Azathioprine; Chronic Disease; Drug Therapy, C

1997
Effect of immunosuppression on obliterative lesions in a heterotopic large-animal bronchial allograft model.
    Transplantation proceedings, 1997, Volume: 29, Issue:7

    Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Cartilage; Cyclosporine; Drug Therapy, Com

1997
Effect of different immunosuppressive agents on acute pancreatitis: a comparative study in an improved animal model.
    Transplantation, 1998, Apr-27, Volume: 65, Issue:8

    Topics: Acute Disease; Animals; Azathioprine; Cyclosporine; Immunosuppressive Agents; Male; Muromonab-CD3; N

1998
Effects of rapamycin analogue SDZ RAD on obliterative lesions in a porcine heterotopic bronchial allograft model.
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Cartilage; Cyclosporine; Epithelium; Evero

1998
Cyclophosphamide therapy of severe systemic necrotizing vasculitis.
    The New England journal of medicine, 1979, Aug-02, Volume: 301, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Cyclophosphamide; Female; Humans; Male; Mi

1979
A new therapeutic strategy in systemic vasculitis?
    The New England journal of medicine, 1979, Aug-02, Volume: 301, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Azathioprine; Cyclophosphamide; Humans; Necrosis; Po

1979
Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression.
    Journal of neurology, 1979, Jan-05, Volume: 220, Issue:4

    Topics: Azathioprine; Brain Neoplasms; Female; Humans; Immunosuppressive Agents; Lymphoma; Middle Aged; Necr

1979
Intestinal necrosis and perforation after renal transplantation.
    Archives of surgery (Chicago, Ill. : 1960), 1975, Volume: 110, Issue:3

    Topics: Adult; Azathioprine; Humans; Immunosuppression Therapy; Intestinal Diseases; Intestinal Perforation;

1975
Necrotizing mesenteric vasculitis after longstanding cutaneous polyarteritis nodosa.
    The Journal of rheumatology, 1992, Volume: 19, Issue:8

    Topics: Adult; Azathioprine; Cyclophosphamide; Dapsone; Female; Humans; Mesenteric Arteries; Methotrexate; N

1992
Renal transplants with multiple arteries.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Anastomosis, Surgical; Arteries; Azathioprine; Follow-Up Studies; Graft Survival; Humans; Kidney Tra

1992
Frequency and significance of chronic ulcerative colitis in severe corticosteroid-treated autoimmune hepatitis.
    Journal of hepatology, 1992, Volume: 14, Issue:2-3

    Topics: Adult; Autoimmune Diseases; Azathioprine; Cholangiography; Colitis, Ulcerative; Female; Follow-Up St

1992
Duodenal gross and microscopic findings after spleno-duodeno-pancreatic allotransplantation in the pig.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Azathioprine; Cyclosporine; Duodenum; Female; Graft Rejection; Intestinal Mucosa; Necrosis;

1992
Immunomodulators interfere with angiopathy but not vasospasm after subarachnoid haemorrhage in rabbits.
    Acta neurochirurgica, 1991, Volume: 108, Issue:1-2

    Topics: Animals; Azathioprine; Cerebral Arteries; Cyclosporins; Endothelium, Vascular; Inosine Pranobex; Isc

1991
Acute adenovirus hepatitis in liver transplant recipients.
    The Journal of pediatrics, 1992, Volume: 120, Issue:1

    Topics: Adenovirus Infections, Human; Adenoviruses, Human; Azathioprine; Biliary Atresia; Child, Preschool;

1992
Glucocorticoids and immunosuppressants do not change the prevalence of necrosis and regeneration in mdx skeletal muscles.
    Muscle & nerve, 1991, Volume: 14, Issue:8

    Topics: Animals; Azathioprine; Cyclophosphamide; Cyclosporins; Immunosuppressive Agents; Methylprednisolone;

1991
Immunopathological patterns in long-term renal allografts.
    Transplantation, 1991, Volume: 51, Issue:3

    Topics: Azathioprine; Biopsy, Needle; Cyclosporins; Drug Therapy, Combination; Follow-Up Studies; Graft Reje

1991
Coombs-positive giant cell hepatitis of infancy: effect of steroids and azathioprine therapy.
    European journal of pediatrics, 1991, Volume: 150, Issue:5

    Topics: Acute Disease; Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Azathioprine; Coombs Test; Dr

1991
Use of duplex ultrasound scanning in renal transplantation.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Adult; Aged; Azathioprine; Cyclosporins; Female; Graft Rejection; Humans; Kidney; Kidney Transplanta

1989
Analysis of biliary complications following orthotopic liver transplantation.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Child; Cyclosporins; Drug Therapy, Combination; Gallbladd

1989
Effects of cyclosporine on glucose metabolism in kidney transplant recipients and rats.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 2

    Topics: Animals; Azathioprine; Blood Glucose; Cyclosporins; Glucagon; Humans; Immunoenzyme Techniques; Insul

1987
Early acute tubular necrosis, late rejection in pediatric renal transplantation with donor-specific transfusions.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 2

    Topics: Azathioprine; Blood Transfusion; Child; Erythrocyte Transfusion; Female; Graft Rejection; Graft Surv

1987
The effect of acute tubular necrosis on cyclosporine-treated kidney transplants.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 3

    Topics: Azathioprine; Creatinine; Cyclosporins; Graft Survival; Humans; Kidney Transplantation; Kidney Tubul

1987
Reduction of the risk of acute tubular necrosis in ciclosporin-treated patients.
    Contributions to nephrology, 1986, Volume: 51

    Topics: Acute Kidney Injury; Adolescent; Adult; Azathioprine; Creatinine; Cyclosporins; Female; Graft Reject

1986
Azathioprine hypersensitivity manifesting as acute focal hepatocellular necrosis.
    Journal of the Royal Society of Medicine, 1986, Volume: 79, Issue:3

    Topics: Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity;

1986
Variation in serum type III procollagen peptide with age in healthy subjects and its comparative value in the assessment of disease activity in children and adults with chronic active hepatitis.
    European journal of clinical investigation, 1985, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Azathioprine; Child; Child, Preschool; Hepatitis, Chronic; Humans; I

1985
Epiphyseal osteonecrosis in transplanted patients: effect of surgical treatment.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1972, Volume: 9

    Topics: Adolescent; Adult; Age Factors; Antilymphocyte Serum; Arthroplasty; Azathioprine; Bone Diseases; Chi

1972
Arteritis with impaired renal function.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0

    Topics: Adult; Aged; Anticoagulants; Azathioprine; Biopsy; Cyclophosphamide; Dipyridamole; Drug Therapy, Com

1973
Systemic (allergic?) vasculitis.
    The Journal of allergy and clinical immunology, 1974, Volume: 54, Issue:1

    Topics: Antigen-Antibody Complex; Azathioprine; Complement System Proteins; Creatinine; Diphenhydramine; Ery

1974
Clinical and pathologic observations after orthotopic transplantation of the human liver.
    Surgery, gynecology & obstetrics, 1969, Volume: 128, Issue:2

    Topics: Adolescent; Adult; Alkaline Phosphatase; Azathioprine; Bilirubin; Blood Proteins; Carcinoma, Hepatoc

1969
[Report of experience with homologous liver transplantation].
    Deutsche medizinische Wochenschrift (1946), 1969, Aug-29, Volume: 94, Issue:35

    Topics: Adult; Alkaline Phosphatase; Antibodies, Anti-Idiotypic; Azathioprine; Bilirubin; Blood Proteins; Bo

1969
Orthotopic liver transplantation in man.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: Adrenal Gland Diseases; Adult; Anticoagulants; Antilymphocyte Serum; Azathioprine; Blood Coagulation

1969
Treatment of lupus nephritis.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1974, Issue:4

    Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Azathioprine; Cyclophosphamide; Hip; Humans

1974
Renal homotransplantation in children.
    American journal of surgery, 1972, Volume: 124, Issue:2

    Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Cataract; Child; Child, Preschool; Evaluation Studie

1972
[Aseptic osteonecrosis after preventive and curative treatment with immunodepressive agents. Phenomena of rejection after renal transplantation].
    Bruxelles medical, 1973, Volume: 53, Issue:10

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Bone Diseases; Female; Femur Head Necrosis; Graft Rejecti

1973
Successful orthotopic transplantation of the canine liver after prolonged preservation by initial perfusion and cold storage.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1973, Volume: 5, Issue:4

    Topics: Animals; Antifibrinolytic Agents; Azathioprine; Catheterization; Dogs; Graft Rejection; Hemorrhagic

1973
Chronic active hepatitis without hepatitis B antigenemia in renal transplant recipients. Report of three cases.
    Gastroenterology, 1974, Volume: 66, Issue:6

    Topics: Adult; Autopsy; Azathioprine; Biopsy; Chronic Disease; Cyclophosphamide; Esophageal and Gastric Vari

1974
Immunosuppression in arterial and venous allografts.
    Archives of surgery (Chicago, Ill. : 1960), 1973, Volume: 106, Issue:1

    Topics: Animals; Arteries; Azathioprine; Carotid Arteries; Dogs; Graft Rejection; Immunosuppression Therapy;

1973
Avascular necrosis of bone in systemic lupus erythematosus.
    The Journal of pediatrics, 1974, Volume: 85, Issue:1

    Topics: Adolescent; Adult; Azathioprine; Blood Vessels; Bone and Bones; Bone Diseases; Child; Female; Femur;

1974
Some histological features of canine cardiac transplants.
    Thorax, 1967, Volume: 22, Issue:5

    Topics: Animals; Azathioprine; Coronary Vessels; Dogs; Heart Transplantation; Heart Valves; Myocardium; Necr

1967
Rejection of the cardiac transplant.
    The American journal of cardiology, 1969, Volume: 24, Issue:4

    Topics: Acute Disease; Adult; Animals; Arteries; Azathioprine; Chronic Disease; Coronary Vessels; Dogs; Edem

1969
Function of auxiliary liver allografts.
    Surgery, gynecology & obstetrics, 1970, Volume: 130, Issue:4

    Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Azathioprine; Bile Ducts; Bilirubin; Dog

1970
Histologic changes associated with rejection of canine lung transplants.
    The Journal of thoracic and cardiovascular surgery, 1971, Volume: 62, Issue:2

    Topics: Animals; Azathioprine; Biopsy; Dogs; Edema; Graft Rejection; Hemorrhage; Immunosuppression Therapy;

1971
Destructive joint changes following kidney transplantation. Report of a case.
    The Journal of bone and joint surgery. British volume, 1971, Volume: 53, Issue:3

    Topics: Arthrodesis; Azathioprine; Humans; Kidney Transplantation; Knee; Knee Joint; Male; Middle Aged; Necr

1971
Acute and modified rejection of heterotopic canine cardiac allotransplants studied by serial needle biopsy.
    Thorax, 1971, Volume: 26, Issue:5

    Topics: Animals; Azathioprine; Biopsy; Dogs; Graft Rejection; Heart Transplantation; Hydrocortisone; Immunit

1971
Histopathology of orthotopic canine cardiac homografts and its clinical correlation.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Dogs; Electrocardiography; Epithelial Cells; Graft Reje

1969
Acute massive hepatic necrosis with fatal liver failure.
    The American journal of digestive diseases, 1971, Volume: 16, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Antitubercular Agents; Azathioprine; Blood

1971
Natural history of active chronic hepatitis. II. Pathology, pathogenesis and clinico-pathological correlation.
    Australasian annals of medicine, 1968, Volume: 17, Issue:4

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Biliary Tract Disease

1968
Leukemia L 1210 homograft in Swiss mice: immunologic, cellular and chemotherapeutic responses.
    Journal of immunology (Baltimore, Md. : 1950), 1969, Volume: 103, Issue:2

    Topics: Animals; Antibody Formation; Azathioprine; Complement System Proteins; Cortisone; Hemagglutination T

1969