Page last updated: 2024-10-23

azathioprine and Myositis

azathioprine has been researched along with Myositis in 95 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Myositis: Inflammation of a muscle or muscle tissue.

Research Excerpts

ExcerptRelevanceReference
"A controlled, prospective, double-blind, therapeutic trial of azathioprine was conducted in the initial therapy of polymyositis."9.05Azathioprine with prednisone for polymyositis. A controlled, clinical trial. ( Bunch, TW; Combs, JJ; Engel, AG; Ilstrup, DM; Worthington, JW, 1980)
" The objective of this study was to evaluate the effect of AZA and MMF on lung function and prednisone dose in myositis-related ILD (M-ILD)."7.91Long-Term Treatment With Azathioprine and Mycophenolate Mofetil for Myositis-Related Interstitial Lung Disease. ( Albayda, J; Casal-Dominguez, M; Christopher-Stine, L; Danoff, SK; Huapaya, JA; Johnson, C; Mammen, AL; Paik, JJ; Pinal-Fernandez, I; Sanyal, A; Silhan, L, 2019)
"An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations."7.75Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009)
"We describe an unusual hypersensitivity reaction to azathioprine occurring in a patient with dermatomyositis, in which the acute manifestations suggested an exacerbation of the patient's underlying disorder."7.65Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis. ( Goldenberg, DL; Stor, RA, 1975)
"Azathioprine treatment was commenced, and despite poor prepregnancy follow-up, her pregnancy remained uneventful until 39 weeks, when fetal ultrasonography showed oligohydramnios."5.72A 25-Year-Old Saudi Woman with a 2-Year History of Antisynthetase Syndrome with Interstitial Lung Disease Who Commenced Azathioprine Treatment in the Third Trimester of Pregnancy and Had a Successful Birth at Term. ( Alshwairikh, LA; Babay, Z, 2022)
"Thirty patients with refractory myositis, of whom 25 had an inadequate or no response to previous cytotoxic therapy, were randomized to begin either a combination of weekly oral methotrexate and daily azathioprine (MTX/AZA) or intravenous methotrexate with leucovorin rescue (I."5.08Treatment of refractory myositis: a randomized crossover study of two new cytotoxic regimens. ( Adams, EM; Burgess, SH; Gourley, MF; Hicks, JE; Leff, RL; Miller, FW; Plotz, PH; Sherman, JB; Thornton, BC; Villalba, L, 1998)
"A controlled, prospective, double-blind, therapeutic trial of azathioprine was conducted in the initial therapy of polymyositis."5.05Azathioprine with prednisone for polymyositis. A controlled, clinical trial. ( Bunch, TW; Combs, JJ; Engel, AG; Ilstrup, DM; Worthington, JW, 1980)
" The objective of this study was to evaluate the effect of AZA and MMF on lung function and prednisone dose in myositis-related ILD (M-ILD)."3.91Long-Term Treatment With Azathioprine and Mycophenolate Mofetil for Myositis-Related Interstitial Lung Disease. ( Albayda, J; Casal-Dominguez, M; Christopher-Stine, L; Danoff, SK; Huapaya, JA; Johnson, C; Mammen, AL; Paik, JJ; Pinal-Fernandez, I; Sanyal, A; Silhan, L, 2019)
"Our patient with SSC-myositis overlap and severe dysphagia requiring PEG feeding, improved with high dose corticosteroids, azathioprine, two courses of IVIG and rituximab, and remained in remission 20 months after hospital discharge."3.85Recovery from severe dysphagia in systemic sclerosis - myositis overlap: a case report. ( Chinniah, KJ; Mody, GM, 2017)
"An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations."3.75Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009)
"A 67-year-old patient, with primary polymyositis and without previous evidence of liver disease, developed clinical and biochemical features of severe cholestasis 3 months after initiation of azathioprine therapy."3.68Reversible cholestasis with bile duct injury following azathioprine therapy. A case report. ( Geubel, AP; Horsmans, Y; Rahier, J, 1991)
"The overall prognosis for polymyositis and dermatomyositis has improved with the judicious use of corticosteroids, while azathioprine and other cytotoxic agents are of value in improving functional ability and decreasing the total steroid requirement."3.67Management of polymyositis and dermatomyositis. ( Ansell, BM, 1984)
"A 29 year old woman with polymyositis treated with azathioprine presented with pneumonia."3.66Legionnaires' disease in a patient with polymyositis. ( Faoagali, JL; McDonald, KS; Moller, PW; Tait, GB, 1980)
"Azathioprine (150 mg daily) was given to 14 patients with polymyositis."3.65[Immunosuppressive treatment of polymyositis]. ( Lurati, M; Mertens, HG, 1975)
"We describe an unusual hypersensitivity reaction to azathioprine occurring in a patient with dermatomyositis, in which the acute manifestations suggested an exacerbation of the patient's underlying disorder."3.65Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis. ( Goldenberg, DL; Stor, RA, 1975)
"All met criteria for a definite idiopathic inflammatory myopathy and had biopsy-proven IBM."2.67The treatment of inclusion body myositis: a retrospective review and a randomized, prospective trial of immunosuppressive therapy. ( Fraser, DD; Hicks, J; Leff, RL; Miller, FW; Plotz, PH, 1993)
"To review advances in the management of idiopathic inflammatory myopathy-associated interstitial lung disease (IIM-associated ILD) in the past 5 years, with highlights in myositis-specific antibody (MSA) groups."2.58Management of Interstitial Lung Disease in Patients With Myositis Specific Autoantibodies. ( Christopher-Stine, L; Mecoli, CA, 2018)
"The management of patients with idiopathic inflammatory myopathy (IIM) remains a challenge given the systemic features beyond active myositis."2.53Update on the pharmacological treatment of adult myositis. ( Oddis, CV, 2016)
"Interstitial lung disease is commonly associated with the autoimmune inflammatory myopathies dermatomyositis and polymyositis and accounts for significant morbidity and mortality in these conditions."2.46Interstitial lung disease associated with the idiopathic inflammatory myopathies: what progress has been made in the past 35 years? ( Christopher-Stine, L; Connors, GR; Danoff, SK; Oddis, CV, 2010)
"Crohn's disease is a chronic relapsing inflammatory disorder primarily affecting the gastrointestinal system."2.39[Myositis--a rare complication of Crohn disease]. ( Druschky, A; Engelhardt, A; Heckmann, J, 1996)
"Almost all types of idiopathic inflammatory myopathy (IIM) are treated by immune-modulating therapies."1.91[Therapeutic Strategies for Idiopathic Inflammatory Myopathies]. ( Tomimitsu, H, 2023)
"Polymyositis is an immune-mediated inflammatory myopathy usually presenting with weakness of proximal muscles in a symmetric pattern."1.72Generalised oedema as a presenting manifestation of inflammatory myopathy. ( Chandra, A; Ghosh, SK; Karmakar, P; Karmakar, PS; Ray, AK, 2022)
"Azathioprine treatment was commenced, and despite poor prepregnancy follow-up, her pregnancy remained uneventful until 39 weeks, when fetal ultrasonography showed oligohydramnios."1.72A 25-Year-Old Saudi Woman with a 2-Year History of Antisynthetase Syndrome with Interstitial Lung Disease Who Commenced Azathioprine Treatment in the Third Trimester of Pregnancy and Had a Successful Birth at Term. ( Alshwairikh, LA; Babay, Z, 2022)
"A muscle biopsy was consistent with inflammatory myopathy."1.51Antisynthetase syndrome presenting as interstitial lung disease: a case report. ( Badshah, A; Haider, I; Humayun, M; Pervez, S, 2019)
"Extended diagnostic measures revealed interstitial lung disease (ILD), polyserositis, polyarthritis and myopathy."1.51[Progressive respiratory failure and weakness in a 61-year-old woman]. ( Mahmud, M; Schnoor, U; Steinmetz, OM, 2019)
"Eruptive melanocytic nevi (EMN) are rare multiple benign melanocytic nevi that develop within a few months."1.46Eruptive melanocytic nevi during azathioprine therapy for antisynthetase syndrome. ( Dronavalli, S; Halvorson, CR; Kao, GF; Steinweg, SA, 2017)
"Subgroup of idiopathic inflammatory myopathies, the antisynthetase syndrome is a rare chronic autoimmune disease, which is characterised by the presence of antibodies directed against aminoacyl-t-RNA-synthetases (family of intracytoplasmic enzymes with a vital role in the protein synthesis)."1.42Interstitial lung disease as first clinical manifestation within the antisynthetase syndrome--dermatomyositis. ( Mlădinescu, OF; Oancea, C; Trăilă, D; Tudorache, V, 2015)
"Macrophagic myofasciitis (MMF) is a rare inflammatory muscle disorder characterized by a characteristic infiltration of muscle tissue by PAS-positive macrophages, which is caused by pathological persistence of vaccine-derived aluminium hydroxide."1.32[Macrophagic myofasciitis: inflammatory, vaccination-associated muscular disease]. ( Fischer, D; Reimann, J; Schröder, R, 2003)
"Idiopathic focal myositis is a rare clinical entity and is mostly localized in the neck and thigh muscles presenting as a pseudotumor."1.30Myositis of small foot muscles. ( Kalden, P; Krause, T; Peter, HH; Volk, B; von Kempis, J, 1998)
"Extraocular polymyositis is a rare orbital disease in dogs and has to our knowledge never been described in other domestic animals."1.30[Eosinophilic myositis of the extraocular muscles. A case report]. ( Mitra, S, 1998)
"Inclusion body myositis is an increasingly recognised form of inflammatory myopathy with characteristic clinical and histopathological features which has seldom been reported in the United Kingdom."1.29Inclusion body myositis: an underdiagnosed condition? ( Hopkinson, ND; Hunt, C; Lowe, J; Powell, RJ, 1993)
"Inclusion body myositis is characterized by an insidious onset, progressive indolent course, and is generally felt to be refractory to standard therapy for myositis."1.28Inclusion body myositis: analysis of 32 cases. ( Calabrese, LH; Chou, SM; Sayers, ME, 1992)
"Inclusion body myositis has been described as an inflammatory myopathy with distinctive clinical and pathologic features that is refractory to treatment."1.28Clinical heterogeneity and treatment response in inclusion body myositis. ( Cohen, MR; Garancis, JC; Sulaiman, AR; Wortmann, RL, 1989)
" The mean dosage of azathioprin and prednisone in patients with SLE did not significantly differ from the non-SLE group."1.27[Reactivation of the alpha 1-fetoprotein synthesis in systemic lupus erythematosus]. ( Knopf, B; Schulze, M; Wollina, U, 1985)
"Polymyositis is a treatable and curable disease."1.26Polymyositis. ( Bradley, WG, 1977)

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-199046 (48.42)18.7374
1990's18 (18.95)18.2507
2000's7 (7.37)29.6817
2010's19 (20.00)24.3611
2020's5 (5.26)2.80

Authors

AuthorsStudies
Mehta, P1
Rathore, U1
Naveen, R1
Chatterjee, R1
Agarwal, V1
Aggarwal, R1
Gupta, L1
Ray, AK1
Karmakar, P1
Chandra, A1
Ghosh, SK1
Karmakar, PS1
Alshwairikh, LA1
Babay, Z1
Tomimitsu, H1
Yoshida, A1
Katsumata, Y1
Hirahara, S1
Hanaoka, M1
Ochiai, M1
Kobayashi, M1
Harigai, M1
Steinweg, SA1
Halvorson, CR1
Kao, GF1
Dronavalli, S1
Palamuthusingam, D1
Mantha, M1
Dheda, S1
Chinniah, KJ1
Mody, GM1
Gorospe, L1
de la Puente-Bujidos, C1
García-Gómez-Muriel, I1
Barbolla-Díaz, I1
Fernández-Méndez, MÁ1
Mecoli, CA1
Christopher-Stine, L3
Mahmud, M1
Schnoor, U1
Steinmetz, OM1
Huapaya, JA1
Silhan, L1
Pinal-Fernandez, I1
Casal-Dominguez, M1
Johnson, C1
Albayda, J1
Paik, JJ1
Sanyal, A1
Mammen, AL1
Danoff, SK2
Badshah, A1
Haider, I1
Pervez, S1
Humayun, M1
Bozkirli, DE1
Kozanoglu, I1
Bozkirli, E1
Yucel, E1
Marie, I1
Hatron, PY1
Cherin, P1
Hachulla, E1
Diot, E1
Vittecoq, O1
Menard, JF1
Jouen, F1
Dominique, S1
Morales, E1
Rabasco, C1
Panizo, N1
Gutierrez, E1
Martinez, MA1
Toldos, O1
Praga, M1
Trăilă, D1
Mlădinescu, OF1
Oancea, C1
Tudorache, V1
Ng, F1
Chiong, FJ1
Buchanan, R1
Burrell, LM1
Oddis, CV3
Oflazer, PS1
Gundesli, H1
Zorludemir, S1
Sabuncu, T1
Dincer, P1
Chakour, R1
Leimgruber, A1
Bart, PA1
Spertini, F1
Karadeli, E1
Ulu, EM1
Connors, GR1
Patel, HC1
Lauder, NN1
Spoon, KC1
Ramar, K1
Zenone, T1
Gibert, C1
Puget, M1
Aynaci, O1
Onder, C1
Kalaycioglu, A1
Fischer, D1
Reimann, J1
Schröder, R1
Kato, T1
Shiratori, K1
Kobashigawa, T1
Hidaka, Y1
Kastrup, A1
Gdynia, HJ1
Nägele, T1
Riecker, A1
Guillen, C1
Fortea, JM1
Serrano, G1
Martorell, MA1
Cogollos, E1
Alegre, V1
Aliaga, A1
Foidart, M1
Liem, HH1
Adornato, BT1
Engel, WK1
Muller-Eberhard, U1
Yang, YC1
Ansell, BM1
Rowen, AJ1
Reichel, J1
McDonald, KS1
Faoagali, JL1
Tait, GB1
Moller, PW1
Bunch, TW2
Worthington, JW1
Combs, JJ1
Ilstrup, DM1
Engel, AG1
Caspi, D1
Fishel, R1
Varon, M1
Yona, E1
Baratz, M1
Yaron, M1
McCune, WJ1
Vallance, DK1
Lynch, JP1
Hopkinson, ND1
Hunt, C1
Powell, RJ1
Lowe, J1
Joffe, MM1
Love, LA1
Leff, RL3
Fraser, DD2
Targoff, IN1
Hicks, JE2
Plotz, PH3
Miller, FW3
Hicks, J1
Druschky, A1
Heckmann, J1
Engelhardt, A1
Villalba, L1
Adams, EM1
Sherman, JB1
Gourley, MF1
Thornton, BC1
Burgess, SH1
Kalden, P1
Krause, T1
Volk, B1
Peter, HH1
von Kempis, J1
Mitra, S1
van Vonderen, MG1
ter Maaten, JC1
van der Valk, P1
Hoorntje, SJ1
Gans, RO1
Pirofsky, B1
Bardana, EJ1
Mathies, H1
Mertens, HG1
Lurati, M1
Riddoch, D1
Morgan-Hughes, JA1
Nemet, D1
Stambuk, D1
Brzović, Z1
Plasaj, M1
Jerusalem, F1
Gundlach, HJ1
Sauerwein, HP1
Bradley, WG1
Hodgkinson, DJ1
Williams, TJ1
Goldenberg, DL1
Stor, RA1
Sayers, ME1
Chou, SM1
Calabrese, LH1
Ehrenstein, MR1
Snaith, ML1
Isenberg, DA1
Lingenfelser, T1
Duerk, H1
Stevens, A1
Grossmann, T1
Knorr, M1
Saal, JG1
Miller, RG2
González-Gay, MA1
Fernández Camblor, B1
Agüero, JJ1
Villarino, MJ1
Eiriz, M1
Mata, I1
Maruyama, T1
Koh, CS1
Inoue, A1
Yanagisawa, N1
Shinoda, T1
Horsmans, Y1
Rahier, J1
Geubel, AP1
Walton, J1
Ramírez, G1
Asherson, RA1
Khamashta, MA1
Cervera, R1
D'Cruz, D1
Hughes, GR2
Wollina, U1
Schulze, M1
Knopf, B1
Cohen, MR1
Sulaiman, AR1
Garancis, JC1
Wortmann, RL1
Lössner, J1
Kühn, HJ1
Lehmann, J1
Ziegan, J1
Small, P1
Lichter, M1
Sabouraud, O1
Clements, PJ1
Davis, J1
Lane, RJ1
Fulthorpe, JJ1
Hudgson, P1
Gruhn, WB1
Diaz-Buxo, JA1
Kingston, WJ1
Moxley, RT1
Morgan, SH1
Bernstein, RM1
Coppen, J1
Halnan, KE1
Corbett, AJ1
Bell, WR1
Hochberg, MC1
Achurra Castillo, AF1
Bulgín, O1
López, RI1
Benítez, R1
Llerena, JM1
Villarreal, V1
Sandoval, E1
Kiprov, DD1
Bradley, JD1
Pinals, RS1
Gupta, RC1
San José, A1
Valdés, M1
Oristrell, J1
Knobel, H1
Bosch, JA1
Swanson, MA1
Schwartz, RS1
Cendrowski, W1
Riekkinen, PJ1
Rinne, UK1
Dawkins, RL1
Mastaglia, FL1
Haas, DC2
Benson, MD1
Aldo, MA1
Lewkonia, RM1
Buxton, PH1
Korz, R1
Volz-Boers, U1
Arnason, BG1
Saporta, L1
Godeau, P1
Delrieu, F1
Delbarre, F1
McFarlin, DE1
Griggs, RC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Placebo-Controlled Trial of Infliximab in Patients With Dermatomyositis and Polymyositis[NCT00033891]Phase 214 participants (Actual)Interventional2002-04-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for azathioprine and Myositis

ArticleYear
Management of Interstitial Lung Disease in Patients With Myositis Specific Autoantibodies.
    Current rheumatology reports, 2018, 04-10, Volume: 20, Issue:5

    Topics: Autoantibodies; Autoimmune Diseases; Azathioprine; Calcineurin Inhibitors; Humans; Immunosuppressive

2018
Update on the pharmacological treatment of adult myositis.
    Journal of internal medicine, 2016, Volume: 280, Issue:1

    Topics: Adrenocorticotropic Hormone; Adult; Azathioprine; Cyclophosphamide; Cyclosporine; Glucocorticoids; H

2016
Interstitial lung disease associated with the idiopathic inflammatory myopathies: what progress has been made in the past 35 years?
    Chest, 2010, Volume: 138, Issue:6

    Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Biomarkers; B

2010
Immunosuppressive drug therapy.
    Current opinion in rheumatology, 1994, Volume: 6, Issue:3

    Topics: Adrenal Cortex Hormones; Azathioprine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cyc

1994
[Myositis--a rare complication of Crohn disease].
    Fortschritte der Neurologie-Psychiatrie, 1996, Volume: 64, Issue:10

    Topics: Azathioprine; Biopsy; Crohn Disease; Drug Therapy, Combination; Humans; Male; Methylprednisolone; Mi

1996
Clinical trials review: idiopathic inflammatory myopathy.
    Current rheumatology reports, 2000, Volume: 2, Issue:3

    Topics: Azathioprine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Immunosuppressive Agents;

2000
Immunosuppressive therapy in rheumatic disease.
    The Medical clinics of North America, 1977, Volume: 61, Issue:2

    Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Dermatomyositis; Gr

1977
[Treatment of myopathies and spinal muscular atrophies (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, Jan-24, Volume: 67, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Azathioprine; Collagen Diseases; Dermatomyositis; Glycogen Storage Di

1978
Neuropathies and myopathies complicating HIV infection.
    Journal of clinical apheresis, 1991, Volume: 6, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Action Potentials; Adult; Antiviral Agents; Azathioprine; Combin

1991
The idiopathic inflammatory myopathies and their treatment.
    Journal of neurology, neurosurgery, and psychiatry, 1991, Volume: 54, Issue:4

    Topics: Adolescent; Adult; Azathioprine; Child; Drug Therapy, Combination; Humans; Muscles; Myositis; Predni

1991
Cytotoxic drugs: their clinical application to the rheumatic diseases.
    Seminars in arthritis and rheumatism, 1986, Volume: 15, Issue:4

    Topics: Arthritis; Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Cell Division; Chemica

1986
Cyclosporine treatment of steroid resistant interstitial pneumonitis associated with dermatomyositis/polymyositis.
    The Journal of rheumatology, 1987, Volume: 14, Issue:5

    Topics: Adult; Azathioprine; Cyclosporins; Dermatomyositis; Drug Resistance; Female; Humans; Myositis; Predn

1987
Treatment of muscular dystrophies and inflammatory myopathies.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:4

    Topics: Azathioprine; Clinical Trials as Topic; Dermatomyositis; Humans; Muscular Dystrophies; Myositis; Myo

1986
Immunosuppressive therapy in neurological diseases.
    Annals of clinical research, 1974, Volume: 6, Issue:6

    Topics: Adrenocorticotropic Hormone; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Cytara

1974

Trials

6 trials available for azathioprine and Myositis

ArticleYear
Azathioprine with prednisone for polymyositis. A controlled, clinical trial.
    Annals of internal medicine, 1980, Volume: 92, Issue:3

    Topics: Adult; Azathioprine; Biopsy; Clinical Trials as Topic; Creatine Kinase; Double-Blind Method; Drug Th

1980
Prednisone and azathioprine for polymyositis: long-term followup.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:1

    Topics: Azathioprine; Clinical Trials as Topic; Follow-Up Studies; Humans; Myositis; Prednisone

1981
The treatment of inclusion body myositis: a retrospective review and a randomized, prospective trial of immunosuppressive therapy.
    Medicine, 1993, Volume: 72, Issue:4

    Topics: Adult; Aged; Autoantibodies; Azathioprine; Drug Therapy, Combination; Female; Humans; Immunosuppress

1993
Treatment of refractory myositis: a randomized crossover study of two new cytotoxic regimens.
    Arthritis and rheumatism, 1998, Volume: 41, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antirheumatic Agents; Azathiopri

1998
Immunosuppressive therapy in rheumatic disease.
    The Medical clinics of North America, 1977, Volume: 61, Issue:2

    Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Dermatomyositis; Gr

1977
Treatment of muscular dystrophies and inflammatory myopathies.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:4

    Topics: Azathioprine; Clinical Trials as Topic; Dermatomyositis; Humans; Muscular Dystrophies; Myositis; Myo

1986

Other Studies

77 other studies available for azathioprine and Myositis

ArticleYear
Prevalent Drug Usage Practices in Adults and Children With Idiopathic Inflammatory Myopathies: Registry-Based Analysis From the MyoCite Cohort.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2022, 03-01, Volume: 28, Issue:2

    Topics: Adult; Azathioprine; Child; Female; Humans; Immunosuppressive Agents; Male; Mycophenolic Acid; Myosi

2022
Generalised oedema as a presenting manifestation of inflammatory myopathy.
    BMJ case reports, 2022, Mar-03, Volume: 15, Issue:3

    Topics: Azathioprine; Edema; Female; Humans; Muscle Weakness; Myositis; Polymyositis

2022
A 25-Year-Old Saudi Woman with a 2-Year History of Antisynthetase Syndrome with Interstitial Lung Disease Who Commenced Azathioprine Treatment in the Third Trimester of Pregnancy and Had a Successful Birth at Term.
    The American journal of case reports, 2022, Jul-07, Volume: 23

    Topics: Adult; Autoantibodies; Autoimmune Diseases; Azathioprine; Female; Humans; Lung Diseases, Interstitia

2022
[Therapeutic Strategies for Idiopathic Inflammatory Myopathies].
    Brain and nerve = Shinkei kenkyu no shinpo, 2023, Volume: 75, Issue:5

    Topics: Adrenal Cortex Hormones; Azathioprine; Humans; Immunosuppressive Agents; Methotrexate; Myositis

2023
Tumour necrosis factor inhibitor-induced myositis in a patient with ulcerative colitis.
    Modern rheumatology case reports, 2021, Volume: 5, Issue:1

    Topics: Azathioprine; Colitis, Ulcerative; Electromyography; Humans; Infliximab; Magnetic Resonance Imaging;

2021
Eruptive melanocytic nevi during azathioprine therapy for antisynthetase syndrome.
    Cutis, 2017, Volume: 99, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azathioprine; Diagnosis, Differential; Female; Foot; Hand; Humans;

2017
HMG CoA reductase inhibitor associated myositis and autoimmune hepatitis.
    Internal medicine journal, 2017, Volume: 47, Issue:10

    Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Diabetes Mellitus, Type 2; Fatal Outcome; Female; Hepa

2017
Recovery from severe dysphagia in systemic sclerosis - myositis overlap: a case report.
    African health sciences, 2017, Volume: 17, Issue:2

    Topics: Adrenal Cortex Hormones; Azathioprine; Cyclophosphamide; Deglutition Disorders; Drug Therapy, Combin

2017
Asymmetric Calcinosis in an Adult Patient With Antisynthetase Syndrome.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:4

    Topics: Amino Acyl-tRNA Synthetases; Autoantibodies; Azathioprine; Calcinosis; Female; Humans; Immunosuppres

2019
[Progressive respiratory failure and weakness in a 61-year-old woman].
    Der Internist, 2019, Volume: 60, Issue:2

    Topics: Amino Acyl-tRNA Synthetases; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Combined Modalit

2019
Long-Term Treatment With Azathioprine and Mycophenolate Mofetil for Myositis-Related Interstitial Lung Disease.
    Chest, 2019, Volume: 156, Issue:5

    Topics: Azathioprine; Enzyme Inhibitors; Female; Follow-Up Studies; Forced Expiratory Volume; Glucocorticoid

2019
Antisynthetase syndrome presenting as interstitial lung disease: a case report.
    Journal of medical case reports, 2019, Aug-04, Volume: 13, Issue:1

    Topics: Adult; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Creatine Kinase; Diagnosis, Differenti

2019
Antisynthetase syndrome with refractory lung involvement and myositis successfully treated with double filtration plasmapheresis.
    Journal of clinical apheresis, 2013, Volume: 28, Issue:6

    Topics: Aged; Autoantibodies; Azathioprine; Combined Modality Therapy; Creatine Kinase; Cyclophosphamide; Em

2013
Functional outcome and prognostic factors in anti-Jo1 patients with antisynthetase syndrome.
    Arthritis research & therapy, 2013, Oct-08, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Azathioprine; Female; Follow-Up

2013
Mesangial nephropathy and anti-synthetase syndrome: An odd association.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2015, Volume: 35, Issue:4

    Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Drug Therapy, Combination; Dyspnea; Edem

2015
Interstitial lung disease as first clinical manifestation within the antisynthetase syndrome--dermatomyositis.
    Pneumologia (Bucharest, Romania), 2015, Volume: 64, Issue:2

    Topics: Adult; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Biomarkers; Dermatomyositis; Disease P

2015
A rare case of Behçet disease with generalised myositis, cardiomyositis and necrotising fasciitis.
    BMJ case reports, 2016, Jan-06, Volume: 2016

    Topics: Adult; Azathioprine; Behcet Syndrome; Fasciitis, Necrotizing; Female; Glucocorticoids; Humans; Immun

2016
Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease?
    Neuromuscular disorders : NMD, 2009, Volume: 19, Issue:4

    Topics: Azathioprine; Calpain; Child; Creatine Kinase; Disease Progression; Dose-Response Relationship, Drug

2009
[Therapeutic strategies in idiopatic inflammatory myopathies].
    Revue medicale suisse, 2009, Apr-15, Volume: 5, Issue:199

    Topics: Adolescent; Age Factors; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Biopsy; Dermatomyos

2009
Acute sarcoid myositis with unusual radiologic findings.
    Diagnostic and interventional radiology (Ankara, Turkey), 2010, Volume: 16, Issue:3

    Topics: Anti-Inflammatory Agents; Azathioprine; Blood Sedimentation; C-Reactive Protein; Humans; Immunosuppr

2010
The antisynthetase syndrome.
    The American journal of medicine, 2011, Volume: 124, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Azathioprine; Cryptogenic Organizing Pneum

2011
Unexplained hypoxemia.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2011, Dec-15, Volume: 7, Issue:6

    Topics: Ascorbic Acid; Azathioprine; Blood Gas Analysis; Dapsone; Female; Follow-Up Studies; Humans; Hyperca

2011
Calcinosis and antisynthetase syndrome.
    Joint bone spine, 2012, Volume: 79, Issue:5

    Topics: Azathioprine; Calcinosis; Comorbidity; Drug Therapy, Combination; Electromyography; Female; Hand Joi

2012
Anterior tibial compartment syndrome due to the pyomyositis in a patient with rheumatoid arthritis. A case report.
    Joint bone spine, 2003, Volume: 70, Issue:1

    Topics: Adult; Anterior Compartment Syndrome; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal

2003
[Macrophagic myofasciitis: inflammatory, vaccination-associated muscular disease].
    Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44

    Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Biopsy; Electromyography; Fasciitis; Follow-Up Studies;

2003
Systemic lupus erythematosus with organic brain syndrome: serial electroencephalograms accurately evaluate therapeutic efficacy.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:2

    Topics: Azathioprine; Cerebrospinal Fluid; Cyclophosphamide; Disorders of Excessive Somnolence; Electroencep

2006
Dropped-head syndrome due to steroid responsive focal myositis: a case report and review of the literature.
    Journal of the neurological sciences, 2008, Apr-15, Volume: 267, Issue:1-2

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Biopsy; Di

2008
Multicentric reticulohistiocytosis.
    Dermatologica, 1984, Volume: 169, Issue:5

    Topics: Arthritis; Azathioprine; Humans; Lymphatic Diseases; Male; Middle Aged; Myositis; Skin Neoplasms

1984
Hemopexin metabolism in patients with altered serum levels.
    The Journal of laboratory and clinical medicine, 1983, Volume: 102, Issue:5

    Topics: Adolescent; Adult; Aged; Azathioprine; Creatine Kinase; Female; Hemopexin; Humans; Male; Middle Aged

1983
[Simple type of multiple myositis--report of 23 cases].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1983, Volume: 16, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Electromyography; Female; Humans; M

1983
Management of polymyositis and dermatomyositis.
    Clinics in rheumatic diseases, 1984, Volume: 10, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Calcinosis; Child; Child, Preschool;

1984
Dermatomyositis with lung involvement, successfully treated with azathioprine.
    Respiration; international review of thoracic diseases, 1983, Volume: 44, Issue:2

    Topics: Adult; Azathioprine; Dermatomyositis; Humans; Lung Diseases; Male; Myositis

1983
Legionnaires' disease in a patient with polymyositis.
    The New Zealand medical journal, 1980, Jun-25, Volume: 91, Issue:662

    Topics: Adult; Antibodies, Bacterial; Azathioprine; Drug Combinations; Female; Humans; Legionnaires' Disease

1980
Multisystem presentation of eosinophilic fasciitis.
    Rheumatology and rehabilitation, 1982, Volume: 21, Issue:4

    Topics: Adult; Ankle Joint; Azathioprine; Blood Sedimentation; Bone Marrow Examination; Elbow Joint; Eosinop

1982
Azathioprine and prednisone in polymyositis.
    Annals of internal medicine, 1980, Volume: 93, Issue:1

    Topics: Azathioprine; Drug Evaluation; Humans; Myositis; Prednisone

1980
Inclusion body myositis: an underdiagnosed condition?
    Annals of the rheumatic diseases, 1993, Volume: 52, Issue:2

    Topics: Aged; Aged, 80 and over; Azathioprine; Female; Humans; Inclusion Bodies; Male; Microscopy, Electron;

1993
Drug therapy of the idiopathic inflammatory myopathies: predictors of response to prednisone, azathioprine, and methotrexate and a comparison of their efficacy.
    The American journal of medicine, 1993, Volume: 94, Issue:4

    Topics: Adult; Autoantibodies; Azathioprine; Cohort Studies; Female; Humans; Inclusion Bodies; Logistic Mode

1993
Myositis of small foot muscles.
    Rheumatology international, 1998, Volume: 18, Issue:2

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Azathioprine; Biopsy; Female; Foot Diseases; Humans;

1998
[Eosinophilic myositis of the extraocular muscles. A case report].
    Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere, 1998, Volume: 26, Issue:5

    Topics: Animals; Azathioprine; Diagnosis, Differential; Dog Diseases; Dogs; Drug Therapy, Combination; Femal

1998
[Myositis in the presence of slightly elevated creatine kinase values].
    Nederlands tijdschrift voor geneeskunde, 1999, May-01, Volume: 143, Issue:18

    Topics: Adult; Azathioprine; Biopsy; Creatine Kinase; Diagnosis, Differential; Humans; Male; Middle Aged; Mu

1999
[Azathioprine in rheumatology].
    Fortschritte der Medizin, 1979, Dec-20, Volume: 97, Issue:48

    Topics: Arthritis, Rheumatoid; Azathioprine; Chromosome Aberrations; Humans; Immunosuppression Therapy; Lupu

1979
[Immunosuppressive treatment of polymyositis].
    Deutsche medizinische Wochenschrift (1946), 1975, Jan-10, Volume: 100, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Azathioprine; Child; Dactinomycin; Female; Huma

1975
Prognosis in adult polymyositis.
    Journal of the neurological sciences, 1975, Volume: 26, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Azathioprine; Clinical Enzyme Tests; Creatine

1975
[Corticosteroid therapy of polymyositis].
    Neurologija, 1979, Volume: 27, Issue:1-4

    Topics: Adult; Azathioprine; Dermatomyositis; Drug Administration Schedule; Drug Therapy, Combination; Femal

1979
[Immunosuppressive therapy of polymyositis].
    Psychiatrie, Neurologie und medizinische Psychologie. Beihefte, 1975, Volume: 20-21

    Topics: Adult; Animals; Autoimmune Diseases; Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Huma

1975
[A patient with muscle weakness].
    Nederlands tijdschrift voor geneeskunde, 1977, Apr-16, Volume: 121, Issue:16

    Topics: Aged; Arthritis, Rheumatoid; Autoantibodies; Azathioprine; Complement System Proteins; Cryoglobulins

1977
Polymyositis.
    British journal of hospital medicine, 1977, Volume: 17, Issue:4

    Topics: Azathioprine; Biopsy, Needle; Creatine Kinase; Myositis; Prednisone

1977
Endometrial carcinoma associated with azathioprine and cortisone therapy. A case report.
    Gynecologic oncology, 1977, Volume: 5, Issue:3

    Topics: Adenocarcinoma; Adult; Amenorrhea; Azathioprine; Female; Genital Neoplasms, Female; Humans; Immunity

1977
Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis.
    The Journal of rheumatology, 1975, Volume: 2, Issue:3

    Topics: Acute Disease; Azathioprine; Dermatomyositis; Diagnosis, Differential; Drug Hypersensitivity; Female

1975
Inclusion body myositis: analysis of 32 cases.
    The Journal of rheumatology, 1992, Volume: 19, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Biopsy; Cyclosporine; Demography; Dose-Response Relati

1992
Idiopathic myositis: a rheumatological view.
    Annals of the rheumatic diseases, 1992, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Creatine Kinase; Der

1992
Generalized myositis in Behçet disease: treatment with cyclosporine.
    Annals of internal medicine, 1992, Apr-15, Volume: 116, Issue:8

    Topics: Adult; Azathioprine; Behcet Syndrome; Cyclosporine; Drug Therapy, Combination; Humans; Male; Myositi

1992
[Lupus myopathy refractory to steroid treatment].
    Anales de medicina interna (Madrid, Spain : 1984), 1991, Volume: 8, Issue:10

    Topics: Azathioprine; Biopsy; Drug Resistance; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged; M

1991
[Successful treatment of "steroid-immunosuppressant resistant" polymyositis with immunoadsorption].
    Rinsho shinkeigaku = Clinical neurology, 1991, Volume: 31, Issue:11

    Topics: Antigen-Antibody Complex; Azathioprine; Drug Resistance; Humans; Immunosorbent Techniques; Immunosup

1991
Reversible cholestasis with bile duct injury following azathioprine therapy. A case report.
    Liver, 1991, Volume: 11, Issue:2

    Topics: Azathioprine; Bile Ducts, Intrahepatic; Biopsy; Cholestasis, Intrahepatic; Humans; Male; Middle Aged

1991
Adult-onset polymyositis-dermatomyositis: description of 25 patients with emphasis on treatment.
    Seminars in arthritis and rheumatism, 1990, Volume: 20, Issue:2

    Topics: Adult; Azathioprine; Cyclophosphamide; Dermatomyositis; Female; Follow-Up Studies; Humans; Male; Met

1990
[Reactivation of the alpha 1-fetoprotein synthesis in systemic lupus erythematosus].
    Zeitschrift fur Hautkrankheiten, 1985, Jun-01, Volume: 60, Issue:11

    Topics: Alanine Transaminase; alpha-Fetoproteins; Antibodies; Arthritis, Rheumatoid; Aspartate Aminotransfer

1985
Clinical heterogeneity and treatment response in inclusion body myositis.
    Arthritis and rheumatism, 1989, Volume: 32, Issue:6

    Topics: Adult; Aged; Azathioprine; Female; Humans; Inclusion Bodies; Male; Microscopy, Electron; Middle Aged

1989
[Secondary muscular carnitine deficiency following immunosuppressive treatment].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1989, Volume: 41, Issue:10

    Topics: Adult; Azathioprine; Carnitine; Humans; Lipid Metabolism; Male; Muscles; Muscular Diseases; Myositis

1989
Probable azathioprine hepatotoxicity: a case report.
    Annals of allergy, 1989, Volume: 62, Issue:6

    Topics: Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Mi

1989
[Immunodepressive agents in neurology].
    La Revue du praticien, 1986, Jan-21, Volume: 36, Issue:5

    Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Azathioprine; Cyclophosphamide; Dermatomyositis; Huma

1986
Inclusion body myositis: a case with associated collagen vascular disease responding to treatment.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:3

    Topics: Azathioprine; Cell Nucleus; Dermatomyositis; Drug Therapy, Combination; Humans; Inclusion Bodies; Ma

1985
Total body irradiation and the course of polymyositis.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:7

    Topics: Aged; Azathioprine; Biopsy; Combined Modality Therapy; Duodenal Ulcer; Female; Humans; Male; Methotr

1985
A circulating anticoagulant to factor VIII in a patient with polymyositis: successful treatment with azathioprine.
    The Journal of rheumatology, 1985, Volume: 12, Issue:5

    Topics: Adult; Azathioprine; Factor VIII; Female; Humans; Myositis

1985
[Polymyositis and dermatomyositis in the metropolitan hospital complex of the Panama Department of Social Security. 1973. Clinical review and effects of treatment].
    Revista medica de Panama, 1985, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Dermatomyositis; Female; Humans; Male; Methotrexate; M

1985
Paraproteinemia associated with demyelinating polyneuropathy or myositis: treatment with plasmapheresis and immunosuppressive drugs.
    Artificial organs, 1985, Volume: 9, Issue:1

    Topics: Azathioprine; Cyclophosphamide; Demyelinating Diseases; Female; Humans; Immunosuppressive Agents; Ma

1985
Chronic active hepatitis associated with polymyositis. Association with precipitating mitochondrial M-B antibody.
    The Journal of rheumatology, 1985, Volume: 12, Issue:2

    Topics: Adult; Azathioprine; Enzymes; Hepatitis, Chronic; Humans; Liver; Male; Membrane Proteins; Mitochondr

1985
[Polymyositis, immunosuppressive treatment and cardia neoplasms: casual or causal relation].
    Revista clinica espanola, 1985, Volume: 177, Issue:3

    Topics: Adenocarcinoma; Azathioprine; Cardia; Humans; Male; Middle Aged; Myositis; Stomach Neoplasms

1985
Immunosuppressive therapy. The relation between clinical response and immunologic competence.
    The New England journal of medicine, 1967, Jul-27, Volume: 277, Issue:4

    Topics: Adolescent; Adult; Anemia, Hemolytic, Autoimmune; Antibody Formation; Azathioprine; Chronic Disease;

1967
Cell-mediated cytotoxicity to muscle in polymyositis. Effect of immunosuppression.
    The New England journal of medicine, 1973, Mar-01, Volume: 288, Issue:9

    Topics: Adult; Aged; Animals; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Azathioprine; Chick

1973
Treatment of polymyositis with immunosuppressive drugs.
    Neurology, 1973, Volume: 23, Issue:1

    Topics: Adult; Aged; Aspartate Aminotransferases; Azathioprine; Child; Creatine Kinase; Cyclophosphamide; Dr

1973
Azathioprine therapy in polymyositis.
    Archives of internal medicine, 1973, Volume: 132, Issue:4

    Topics: Adult; Aspartate Aminotransferases; Azathioprine; Child; Creatine Kinase; Female; Follow-Up Studies;

1973
Myositis in father and daughter.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:5

    Topics: Adult; Alanine Transaminase; Azathioprine; Child; Creatine Kinase; Dermatomyositis; Female; Humans;

1973
[Acute renal failure after massive myolysis in pseudomyopathic polymyositis (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, May-17, Volume: 99, Issue:20

    Topics: Acute Kidney Injury; Adult; Azathioprine; Biopsy; Creatine Kinase; Electromyography; Female; Humans;

1974
Cell-mediated immunity in polymyositis. Creatine phosphokinase release from muscle cultures.
    Archives of neurology, 1974, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Azathioprine; Child; Creatine Kinase; Culture Techniqu

1974
[Generalized scleroderma. Treatment with immunosuppressive agents].
    La Nouvelle presse medicale, 1972, Jul-22, Volume: 1, Issue:29

    Topics: Adult; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Male;

1972
Treatment of inflammatory myopathies with azathioprine.
    Transactions of the American Neurological Association, 1968, Volume: 93

    Topics: Adolescent; Azathioprine; Dermatomyositis; Female; Humans; Middle Aged; Myositis

1968