azathioprine has been researched along with Myeloproliferative Disorders in 4 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Myeloproliferative Disorders: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No significant risk for other intestinal cancers was found, especially for small bowel carcinoma." | 1.43 | Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study. ( Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheddani, H | 1 |
| Dauchet, L | 1 |
| Fumery, M | 1 |
| Charpentier, C | 1 |
| Marie Bouvier, A | 1 |
| Dupas, JL | 1 |
| Pariente, B | 1 |
| Peyrin-Biroulet, L | 1 |
| Savoye, G | 1 |
| Gower-Rousseau, C | 1 |
| Burki, TK | 1 |
| Tavadia, SM | 1 |
| Mydlarski, PR | 1 |
| Reis, MD | 1 |
| Mittmann, N | 1 |
| Pinkerton, PH | 1 |
| Shear, N | 1 |
| Sauder, DN | 1 |
| Mey, U | 1 |
| Franke, A | 1 |
| Fuchs, R | 1 |
4 other studies available for azathioprine and Myeloproliferative Disorders
| Article | Year |
|---|---|
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroi | 2016 |
Azathioprine associated with myeloid neoplasm risk.
Topics: Autoimmune Diseases; Azathioprine; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Myelo | 2017 |
Screening for azathioprine toxicity: a pharmacoeconomic analysis based on a target case.
Topics: Adult; Azathioprine; Costs and Cost Analysis; Female; Genetic Testing; Homozygote; Humans; Immunosup | 2000 |
[Acute mature myelocytic leukemia as a form of the myeloproliferative syndrome].
Topics: Acute Disease; Adult; Azathioprine; Bone Marrow Examination; Fetal Hemoglobin; Hematopoietic Stem Ce | 1979 |