azathioprine has been researched along with Muscular Weakness in 22 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations." | 7.75 | Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009) |
| " These observations suggest that the development of muscular weakness in patients on azathioprine should be considered as an adverse effect of the drug." | 5.33 | Severe muscular weakness: an unusual adverse effect of azathioprine therapy. ( Arora, M; Dutta, SK; Karhadkar, AS; Schwartz, HJ, 2006) |
| "In patients with juvenile dermatomyositis, treatment with intravenous immunoglobulin and cyclosporine A were more frequent as compared to adult patients." | 3.81 | [Clinical features of patients with juvenile and adult dermatomyositis]. ( Dankó, K; Farkas, F; Nagy-Vince, M; Szalmás, O, 2015) |
| "An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations." | 3.75 | Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009) |
| " Three patients with long-standing polymyositis (PM) or dermatomyositis (DM) poorly responsive to prednisone combined with several immunosuppressants were given intravenous rituximab 1,000 mg on Days 0 and 14." | 3.73 | Rituximab as therapy for refractory polymyositis and dermatomyositis. ( Hausner-Sypek, DL; Noss, EH; Weinblatt, ME, 2006) |
| "Polymyositis is an immune-mediated inflammatory myopathy usually presenting with weakness of proximal muscles in a symmetric pattern." | 1.72 | Generalised oedema as a presenting manifestation of inflammatory myopathy. ( Chandra, A; Ghosh, SK; Karmakar, P; Karmakar, PS; Ray, AK, 2022) |
| "Its presentation with interstitial lung disease alters its prognosis." | 1.51 | Antisynthetase syndrome presenting as interstitial lung disease: a case report. ( Badshah, A; Haider, I; Humayun, M; Pervez, S, 2019) |
| "A 66-year-old woman with a history of interstitial lung disease presented with a 3-month history of dropped head syndrome (DHS), followed by camptocormia and extremity weakness." | 1.48 | Dropped Head Syndrome and the Presence of Rimmed Vacuoles in a Muscle Biopsy in Scleroderma-polymyositis Overlap Syndrome Associated with Anti-Ku Antibody. ( Higuchi, I; Jonosono, M; Mitsuyo, K; Yoshida, M; Yoshida, T, 2018) |
| "Polymyositis is an inflammatory myopathy which, like SCD, may present with myalgia but is usually associated with proximal muscle weakness." | 1.42 | Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease. ( Bali, S; D'Cruz, D; Inusa, BP; Lazaro, M, 2015) |
| "The sporadic inclusion body myositis weakness composite index, which correlated with grip strength (correlation coefficient: 0." | 1.37 | Long-term observational study of sporadic inclusion body myositis. ( Allenbach, Y; Benveniste, O; Brady, S; Dubourg, O; Eymard, B; Freebody, J; Guiguet, M; Herson, S; Hilton-Jones, D; Leite, MI; Maisonobe, T; Squier, W; Stojkovic, T, 2011) |
| " These observations suggest that the development of muscular weakness in patients on azathioprine should be considered as an adverse effect of the drug." | 1.33 | Severe muscular weakness: an unusual adverse effect of azathioprine therapy. ( Arora, M; Dutta, SK; Karhadkar, AS; Schwartz, HJ, 2006) |
| "Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors." | 1.31 | Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002) |
| "Although most patients with inclusion body myositis have characteristic muscle biopsy findings, some cannot be distinguished histologically early from polymyositis." | 1.29 | Inclusion body myositis: clinical and pathological boundaries. ( Amato, AA; Barohn, RJ; Bryan, WW; Gronseth, GS; Jackson, CE; Katz, JS; Wolfe, GI, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 12 (54.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Ray, AK | 1 |
| Karmakar, P | 1 |
| Chandra, A | 1 |
| Ghosh, SK | 1 |
| Karmakar, PS | 1 |
| Yoshida, T | 1 |
| Yoshida, M | 1 |
| Mitsuyo, K | 1 |
| Jonosono, M | 1 |
| Higuchi, I | 1 |
| Badshah, A | 1 |
| Haider, I | 1 |
| Pervez, S | 1 |
| Humayun, M | 1 |
| Bali, S | 1 |
| D'Cruz, D | 1 |
| Lazaro, M | 1 |
| Inusa, BP | 1 |
| Gao, F | 1 |
| Zhao, X | 1 |
| Zhang, J | 1 |
| Cui, X | 1 |
| Zhang, Y | 2 |
| Li, Q | 1 |
| Liu, P | 1 |
| Fang, H | 1 |
| Du, Y | 1 |
| Zhang, Q | 1 |
| Yang, J | 1 |
| Szalmás, O | 1 |
| Nagy-Vince, M | 1 |
| Dankó, K | 1 |
| Farkas, F | 1 |
| Ong, SG | 1 |
| Ding, HJ | 1 |
| Kostera-Pruszczyk, A | 1 |
| Ryniewicz, B | 1 |
| Rowinska-Marcinska, K | 1 |
| Dutkiewicz, M | 1 |
| Kamińska, A | 1 |
| Oflazer, PS | 1 |
| Gundesli, H | 1 |
| Zorludemir, S | 1 |
| Sabuncu, T | 1 |
| Dincer, P | 1 |
| Mijajlovic, M | 1 |
| Mirkovic, M | 1 |
| Dackovic, J | 1 |
| Zidverc-Trajkovic, J | 1 |
| Sternic, N | 1 |
| Nakamura, H | 1 |
| Fujikawa, K | 1 |
| Kawakami, A | 1 |
| Tamai, M | 1 |
| Yamasaki, S | 1 |
| Ida, H | 1 |
| Eguchi, K | 1 |
| Rigamonti, A | 1 |
| Lauria, G | 1 |
| Piamarta, F | 1 |
| Fiumani, A | 1 |
| Agostoni, E | 1 |
| Benveniste, O | 1 |
| Guiguet, M | 1 |
| Freebody, J | 1 |
| Dubourg, O | 1 |
| Squier, W | 1 |
| Maisonobe, T | 1 |
| Stojkovic, T | 1 |
| Leite, MI | 1 |
| Allenbach, Y | 1 |
| Herson, S | 1 |
| Brady, S | 1 |
| Eymard, B | 1 |
| Hilton-Jones, D | 1 |
| Jung, KD | 1 |
| Kim, PS | 1 |
| Park, HY | 1 |
| Kim, CR | 1 |
| Byun, JY | 1 |
| Lee, DY | 1 |
| Lee, JH | 1 |
| Yang, JM | 1 |
| Lee, ES | 1 |
| Prasad, R | 1 |
| De Silva, M | 1 |
| Noss, EH | 1 |
| Hausner-Sypek, DL | 1 |
| Weinblatt, ME | 1 |
| Karhadkar, AS | 1 |
| Schwartz, HJ | 1 |
| Arora, M | 1 |
| Dutta, SK | 1 |
| Pedersen, K | 1 |
| Pandolfo, M | 1 |
| Mavroudakis, N | 1 |
| Kastrup, A | 1 |
| Gdynia, HJ | 1 |
| Nägele, T | 1 |
| Riecker, A | 1 |
| Amato, AA | 1 |
| Gronseth, GS | 1 |
| Jackson, CE | 1 |
| Wolfe, GI | 1 |
| Katz, JS | 1 |
| Bryan, WW | 1 |
| Barohn, RJ | 1 |
| Rose, MR | 1 |
| Levin, KH | 1 |
| Griggs, RC | 1 |
| Grassia, R | 1 |
| Paolo Coppeta, G | 1 |
| Staiano, T | 1 |
22 other studies available for azathioprine and Muscular Weakness
| Article | Year |
|---|---|
Generalised oedema as a presenting manifestation of inflammatory myopathy.
Topics: Azathioprine; Edema; Female; Humans; Muscle Weakness; Myositis; Polymyositis | 2022 |
Dropped Head Syndrome and the Presence of Rimmed Vacuoles in a Muscle Biopsy in Scleroderma-polymyositis Overlap Syndrome Associated with Anti-Ku Antibody.
Topics: Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Female; Head Movements; Humans; Immuno | 2018 |
Antisynthetase syndrome presenting as interstitial lung disease: a case report.
Topics: Adult; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Creatine Kinase; Diagnosis, Differenti | 2019 |
Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease.
Topics: Adolescent; Adrenal Cortex Hormones; Anemia, Sickle Cell; Anti-Inflammatory Agents; Autoimmunity; Az | 2015 |
Clinical features of patients with Myasthenia gravis from the Henan province, China.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Distribution; Age of Onset; Aged; Aged, 80 and over; | 2016 |
[Clinical features of patients with juvenile and adult dermatomyositis].
Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Cyclosporine; Dermatomyositis; Female; Fol | 2015 |
Patient with statin-associated immune-mediated necrotizing myopathy presenting with subcutaneous edema, persistent bulbar weakness and absent anti-HMGCR.
Topics: Aged; Autoantibodies; Azathioprine; Biopsy; Bulbar Palsy, Progressive; Edema; Glucocorticoids; Human | 2017 |
Lambert-Eaton myasthenic syndrome in childhood.
Topics: Autoantibodies; Azathioprine; Calcium Channels, P-Type; Child; Humans; Immunosuppressive Agents; Lam | 2009 |
Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease?
Topics: Azathioprine; Calpain; Child; Creatine Kinase; Disease Progression; Dose-Response Relationship, Drug | 2009 |
Clinical manifestations, diagnostic criteria and therapy of Hashimoto's encephalopathy: report of two cases.
Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Diagnosis, Differential; Electroencephalography; Encep | 2010 |
Long-term efficacy of intravenously administered immunoglobulin in a case of polymyositis with limited application of steroid therapy.
Topics: Aged; Azathioprine; Creatine Kinase; Cyclosporine; Humans; Immunoglobulins, Intravenous; Immunosuppr | 2010 |
Thymoma-associated myasthenia gravis without acetylcholine receptor antibodies.
Topics: Action Potentials; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Electric Stimulation; Evo | 2011 |
Long-term observational study of sporadic inclusion body myositis.
Topics: Aged; Azathioprine; Cohort Studies; Disability Evaluation; Female; Humans; Immunoglobulins, Intraven | 2011 |
Dermatomyositis associated with generalized subcutaneous edema and Evans syndrome.
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Dermatomyositis; Edema; Female; Glucocorticoids; Humans | 2012 |
Osteoporosis with underlying connective tissue disease: an unusual case.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant | 2002 |
Rituximab as therapy for refractory polymyositis and dermatomyositis.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD19; Azathioprine; B-Lymp | 2006 |
Severe muscular weakness: an unusual adverse effect of azathioprine therapy.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Immunosuppre | 2006 |
Chronic inflammatory demyelinating polyneuropathy in a diabetic patient: deterioration after intravenous immunoglobulins treatment and favorable response to steroid treatment.
Topics: Azathioprine; Diabetic Neuropathies; Disease Progression; Female; Humans; Immunoglobulins, Intraveno | 2007 |
Dropped-head syndrome due to steroid responsive focal myositis: a case report and review of the literature.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Biopsy; Di | 2008 |
Inclusion body myositis: clinical and pathological boundaries.
Topics: Aged; Azathioprine; Biopsy; Creatine Kinase; Dermatomyositis; Diagnosis, Differential; Female; Human | 1996 |
The dropped head plus syndrome: quantitation of response to corticosteroids.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Body Mass Index; Drug Therapy, Combination; Head Movem | 1999 |
Severe muscular weakness as an isolated symptom of azathioprine hypersensitivity.
Topics: Anti-Inflammatory Agents; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Mercaptopurine; | 2011 |