azathioprine has been researched along with Muscular Diseases in 27 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty-five patients with Wegener's granulomatosis were studied for 21 years at the National Institutes of Health." | 3.75 | Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. ( Fauci, AS; Haynes, BF; Katz, P; Wolff, SM, 1983) |
| "We reported a patient with so-called "dropped head plus syndrome", a non-progressive myopathy characterized by striking neck extensor weakness followed by progressive limb weakness which is well controlled by azathioprine." | 3.72 | [Dropped head plus syndrome; a case report]. ( Kita, Y; Morino, K; Nishino, I; Nonaka, I; Tabuchi, M; Yoneda, Y, 2003) |
| " Patients with polyarteritis nodosa (two) or polymyositis (one) were treated with prednisone, which improved their wasting syndrome." | 3.69 | Skeletal muscle studies in patients with HIV-related wasting syndrome. ( Casademont, J; Cebrián, M; Grau, JM; Mallolas, J; Masanés, F; Miró, O; Pedrol, E, 1997) |
| "Febuxostat and AZA were then stopped." | 1.40 | Febuxostat as a novel option to optimize thiopurines' metabolism in patients with inadequate metabolite levels. ( Bégin, J; Doré, M; Frenette, AJ; Mansour, AM; Troyanov, Y, 2014) |
| " The calf pain and limited range of motion of ankle dorsiflexion subsided from day 1 on administration of oral corticosteroid at high dosage and were completely resolved by 4 months." | 1.38 | Muscular polyarteritis nodosa. ( Cho, NS; Choi, HS; Choi, SJ; Kim, DH; Yang, SN; Yoon, ES, 2012) |
| "Sirolimus is an immunosuppressive drug which has proved its effectivity to reduce the incidence of acute rejection in renal transplantation receptors." | 1.32 | [Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case]. ( Gentil, MA; González Roncero, FM; López, M; Martínez, M; Mateos, J; Pereira, P; Rodríguez Algarra, G; Toro, J; Valdivia, MA, 2004) |
| "All but one of 28 patients with mixed connective tissue disease (MCTD) who were studied prospectively had arthralgia, and 15 of them had noticed joint swelling." | 1.26 | Articular manifestations of mixed connective tissue disease. ( Alarcón-Segovia, D; Hernández-Ortíz, J; Ramos-Niembro, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (37.04) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Hunziker, L | 1 |
| Dracklé, J | 1 |
| Ducci, RD | 1 |
| Scola, RH | 1 |
| Lorenzoni, PJ | 1 |
| Kay, CSK | 1 |
| Blood, MRY | 1 |
| Leão, LG | 1 |
| Vainzof, M | 1 |
| Werneck, LC | 1 |
| Hasan, S | 1 |
| Abushahin, A | 1 |
| Prayson, R | 1 |
| Kilani, A | 1 |
| Doré, M | 1 |
| Frenette, AJ | 1 |
| Mansour, AM | 1 |
| Troyanov, Y | 1 |
| Bégin, J | 1 |
| Fernández-Torrón, R | 1 |
| López de Munain, A | 1 |
| Camaño, P | 1 |
| García-Bragado, F | 1 |
| Ong, SG | 1 |
| Ding, HJ | 1 |
| Schoser, B | 1 |
| Jacob, S | 1 |
| Hilton-Jones, D | 1 |
| Müller-Felber, W | 2 |
| Kubisch, C | 1 |
| Claus, D | 1 |
| Goebel, HH | 2 |
| Vita, G | 1 |
| Vincent, A | 1 |
| Toscano, A | 1 |
| Van den Bergh, P | 1 |
| Yang, SN | 1 |
| Cho, NS | 1 |
| Choi, HS | 1 |
| Choi, SJ | 1 |
| Yoon, ES | 1 |
| Kim, DH | 1 |
| Morino, K | 1 |
| Kita, Y | 1 |
| Yoneda, Y | 1 |
| Tabuchi, M | 1 |
| Nishino, I | 1 |
| Nonaka, I | 1 |
| Martínez, M | 1 |
| González Roncero, FM | 1 |
| López, M | 1 |
| Toro, J | 1 |
| Valdivia, MA | 1 |
| Pereira, P | 1 |
| Gentil, MA | 1 |
| Rodríguez Algarra, G | 1 |
| Mateos, J | 1 |
| Golding, RM | 1 |
| Giles, LG | 1 |
| Bachmeyer, C | 1 |
| Tillie-Leblond, I | 1 |
| Lacert, A | 1 |
| Cadranel, J | 1 |
| Aractingi, S | 1 |
| Newsom-Davis, J | 1 |
| Murray, NM | 1 |
| Fauci, AS | 1 |
| Haynes, BF | 1 |
| Katz, P | 1 |
| Wolff, SM | 1 |
| Dau, PC | 1 |
| Denys, EH | 1 |
| Spadaro, M | 1 |
| Tilia, G | 1 |
| Massara, MC | 1 |
| Damiani, A | 1 |
| Parisi, L | 1 |
| Tomelleri, G | 1 |
| D'Offizi, G | 1 |
| Morocutti, C | 1 |
| Solinger, AM | 1 |
| Hess, EV | 1 |
| Miró, O | 1 |
| Pedrol, E | 1 |
| Cebrián, M | 1 |
| Masanés, F | 1 |
| Casademont, J | 1 |
| Mallolas, J | 1 |
| Grau, JM | 1 |
| Ansevin, CF | 1 |
| Ricker, K | 1 |
| Müller-Jenssen, A | 1 |
| Töpfer, M | 1 |
| Pongratz, DE | 1 |
| Jerusalem, F | 1 |
| Ramos-Niembro, F | 1 |
| Alarcón-Segovia, D | 1 |
| Hernández-Ortíz, J | 1 |
| Miller, RG | 1 |
| Lössner, J | 1 |
| Kühn, HJ | 1 |
| Lehmann, J | 1 |
| Ziegan, J | 1 |
| Csuka, M | 1 |
| McCarty, DJ | 1 |
| Clayton, R | 1 |
| Safdar, SH | 1 |
| Krantz, SB | 1 |
| Brown, EB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901] | Phase 2 | 60 participants | Interventional | 1999-02-28 | Completed | ||
| Effectiveness of a Simple Designed Programme of Home Based Exercise in Preventing Fall and Improving Balance and Strength in Older People With Mild to Moderate Balance Dysfunction: A Randomized Controlled Trials[NCT02089815] | 439 participants (Actual) | Interventional | 2013-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for azathioprine and Muscular Diseases
| Article | Year |
|---|---|
"Mechanic's hands": a misleading cutaneous sign of the antisynthetase syndrome.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Antinuclear; Azathioprine; Cyclophosphamide; Diag | 2007 |
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
[Treatment of myopathies and spinal muscular atrophies (author's transl)].
Topics: Amyotrophic Lateral Sclerosis; Azathioprine; Collagen Diseases; Dermatomyositis; Glycogen Storage Di | 1978 |
Neuropathies and myopathies complicating HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Action Potentials; Adult; Antiviral Agents; Azathioprine; Combin | 1991 |
2 trials available for azathioprine and Muscular Diseases
| Article | Year |
|---|---|
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
Myopathy in long-term AZT therapy: clinical, electrophysiological and biopsy study in 67 HIV+ subjects.
Topics: Adult; Azathioprine; Biopsy; Creatine Kinase; Electromyography; Female; HIV Seropositivity; Humans; | 1993 |
22 other studies available for azathioprine and Muscular Diseases
| Article | Year |
|---|---|
[Subacute Flaccid Tetraparesis].
Topics: Autoantibodies; Autoimmune Diseases; Azathioprine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhib | 2022 |
Immune-mediated rippling muscle disease in a patient with treated hypothyroidism.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Female; Humans; Hypothyroidism; Immunologic Facto | 2017 |
When Statins Cause an Autoimmune Response: A Report of a Severe Case of Rhabdomyolysis.
Topics: Aged; Atorvastatin; Autoantibodies; Autoimmune Diseases; Azathioprine; Creatine Kinase; Humans; Hydr | 2020 |
Febuxostat as a novel option to optimize thiopurines' metabolism in patients with inadequate metabolite levels.
Topics: Adult; Azathioprine; Drug Interactions; Enzyme Inhibitors; Febuxostat; Female; Guanine Nucleotides; | 2014 |
Rapidly Reversible Winging Scapula.
Topics: Autoantibodies; Autoimmune Diseases; Azathioprine; Deltoid Muscle; Female; Humans; Immunoglobulins, | 2015 |
Patient with statin-associated immune-mediated necrotizing myopathy presenting with subcutaneous edema, persistent bulbar weakness and absent anti-HMGCR.
Topics: Aged; Autoantibodies; Azathioprine; Biopsy; Bulbar Palsy, Progressive; Edema; Glucocorticoids; Human | 2017 |
Immune-mediated rippling muscle disease with myasthenia gravis: a report of seven patients with long-term follow-up in two.
Topics: Adult; Aged; Autoantibodies; Azathioprine; Caveolae; Caveolin 3; Cholinesterase Inhibitors; Electrom | 2009 |
Muscular polyarteritis nodosa.
Topics: Adult; Azathioprine; Biopsy; Drug Therapy, Combination; Electromyography; Follow-Up Studies; Gait; G | 2012 |
[Dropped head plus syndrome; a case report].
Topics: Aged; Azathioprine; Electromyography; Humans; Immunosuppressive Agents; Male; Muscular Diseases; Nec | 2003 |
[Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case].
Topics: Aged; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diagnosis, Differential; Diuretics; Doxazosi | 2004 |
A method for extracting muscle information from serum creatine kinase measurements--its potential value in the monitoring and management of inflammatory muscle disease.
Topics: Animals; Azathioprine; Clinical Enzyme Tests; Creatine Kinase; Drug Interactions; Humans; Indoles; I | 2006 |
Plasma exchange and immunosuppressive drug treatment in the Lambert-Eaton myasthenic syndrome.
Topics: Action Potentials; Adult; Azathioprine; Carcinoma, Small Cell; Combined Modality Therapy; Electric S | 1984 |
Plasmapheresis and immunosuppressive drug therapy in the Eaton-Lambert syndrome.
Topics: Action Potentials; Aged; Azathioprine; Electric Stimulation; Electromyography; Female; Humans; Male; | 1982 |
Rheumatic diseases and AIDS--is the association real?
Topics: Acquired Immunodeficiency Syndrome; Adult; Azathioprine; Female; Humans; Male; Muscular Diseases; Pa | 1993 |
Skeletal muscle studies in patients with HIV-related wasting syndrome.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Female; HIV Wasting Syndrome; Humans; Immunos | 1997 |
Immunosuppressive treatment of rippling muscles in patients with myasthenia gravis.
Topics: Adult; Azathioprine; Humans; Immunosuppressive Agents; Male; Middle Aged; Muscle Contraction; Muscul | 1999 |
Articular manifestations of mixed connective tissue disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Azathioprine; Child; Female; Huma | 1979 |
[Secondary muscular carnitine deficiency following immunosuppressive treatment].
Topics: Adult; Azathioprine; Carnitine; Humans; Lipid Metabolism; Male; Muscles; Muscular Diseases; Myositis | 1989 |
Simple method for measurement of lower extremity muscle strength.
Topics: Adult; Age Factors; Aged; Azathioprine; Creatine Kinase; Female; Humans; Leg; Male; Middle Aged; Mus | 1985 |
Treatment of myasthenia--I.
Topics: Adrenocorticotropic Hormone; Azathioprine; Bronchial Neoplasms; Carcinoma; Cholinesterase Inhibitors | 1971 |
Letter: Azathioprine in psoriasis.
Topics: Azathioprine; Humans; Male; Middle Aged; Muscle Contraction; Muscular Diseases; Psoriasis | 1974 |
Successful immunosuppressive treatment of erythroid aplasia appearing after thymectomy.
Topics: Anemia, Aplastic; Antibodies, Antinuclear; Azathioprine; Bone Marrow; Cyclophosphamide; Erythropoies | 1970 |