azathioprine has been researched along with Muscle Disorders in 27 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty-five patients with Wegener's granulomatosis were studied for 21 years at the National Institutes of Health." | 3.75 | Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. ( Fauci, AS; Haynes, BF; Katz, P; Wolff, SM, 1983) |
| "We reported a patient with so-called "dropped head plus syndrome", a non-progressive myopathy characterized by striking neck extensor weakness followed by progressive limb weakness which is well controlled by azathioprine." | 3.72 | [Dropped head plus syndrome; a case report]. ( Kita, Y; Morino, K; Nishino, I; Nonaka, I; Tabuchi, M; Yoneda, Y, 2003) |
| " Patients with polyarteritis nodosa (two) or polymyositis (one) were treated with prednisone, which improved their wasting syndrome." | 3.69 | Skeletal muscle studies in patients with HIV-related wasting syndrome. ( Casademont, J; Cebrián, M; Grau, JM; Mallolas, J; Masanés, F; Miró, O; Pedrol, E, 1997) |
| "Febuxostat and AZA were then stopped." | 1.40 | Febuxostat as a novel option to optimize thiopurines' metabolism in patients with inadequate metabolite levels. ( Bégin, J; Doré, M; Frenette, AJ; Mansour, AM; Troyanov, Y, 2014) |
| " The calf pain and limited range of motion of ankle dorsiflexion subsided from day 1 on administration of oral corticosteroid at high dosage and were completely resolved by 4 months." | 1.38 | Muscular polyarteritis nodosa. ( Cho, NS; Choi, HS; Choi, SJ; Kim, DH; Yang, SN; Yoon, ES, 2012) |
| "Sirolimus is an immunosuppressive drug which has proved its effectivity to reduce the incidence of acute rejection in renal transplantation receptors." | 1.32 | [Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case]. ( Gentil, MA; González Roncero, FM; López, M; Martínez, M; Mateos, J; Pereira, P; Rodríguez Algarra, G; Toro, J; Valdivia, MA, 2004) |
| "All but one of 28 patients with mixed connective tissue disease (MCTD) who were studied prospectively had arthralgia, and 15 of them had noticed joint swelling." | 1.26 | Articular manifestations of mixed connective tissue disease. ( Alarcón-Segovia, D; Hernández-Ortíz, J; Ramos-Niembro, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (37.04) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Hunziker, L | 1 |
| Dracklé, J | 1 |
| Ducci, RD | 1 |
| Scola, RH | 1 |
| Lorenzoni, PJ | 1 |
| Kay, CSK | 1 |
| Blood, MRY | 1 |
| Leão, LG | 1 |
| Vainzof, M | 1 |
| Werneck, LC | 1 |
| Hasan, S | 1 |
| Abushahin, A | 1 |
| Prayson, R | 1 |
| Kilani, A | 1 |
| Doré, M | 1 |
| Frenette, AJ | 1 |
| Mansour, AM | 1 |
| Troyanov, Y | 1 |
| Bégin, J | 1 |
| Fernández-Torrón, R | 1 |
| López de Munain, A | 1 |
| Camaño, P | 1 |
| García-Bragado, F | 1 |
| Ong, SG | 1 |
| Ding, HJ | 1 |
| Schoser, B | 1 |
| Jacob, S | 1 |
| Hilton-Jones, D | 1 |
| Müller-Felber, W | 2 |
| Kubisch, C | 1 |
| Claus, D | 1 |
| Goebel, HH | 2 |
| Vita, G | 1 |
| Vincent, A | 1 |
| Toscano, A | 1 |
| Van den Bergh, P | 1 |
| Yang, SN | 1 |
| Cho, NS | 1 |
| Choi, HS | 1 |
| Choi, SJ | 1 |
| Yoon, ES | 1 |
| Kim, DH | 1 |
| Morino, K | 1 |
| Kita, Y | 1 |
| Yoneda, Y | 1 |
| Tabuchi, M | 1 |
| Nishino, I | 1 |
| Nonaka, I | 1 |
| Martínez, M | 1 |
| González Roncero, FM | 1 |
| López, M | 1 |
| Toro, J | 1 |
| Valdivia, MA | 1 |
| Pereira, P | 1 |
| Gentil, MA | 1 |
| Rodríguez Algarra, G | 1 |
| Mateos, J | 1 |
| Golding, RM | 1 |
| Giles, LG | 1 |
| Bachmeyer, C | 1 |
| Tillie-Leblond, I | 1 |
| Lacert, A | 1 |
| Cadranel, J | 1 |
| Aractingi, S | 1 |
| Newsom-Davis, J | 1 |
| Murray, NM | 1 |
| Fauci, AS | 1 |
| Haynes, BF | 1 |
| Katz, P | 1 |
| Wolff, SM | 1 |
| Dau, PC | 1 |
| Denys, EH | 1 |
| Spadaro, M | 1 |
| Tilia, G | 1 |
| Massara, MC | 1 |
| Damiani, A | 1 |
| Parisi, L | 1 |
| Tomelleri, G | 1 |
| D'Offizi, G | 1 |
| Morocutti, C | 1 |
| Solinger, AM | 1 |
| Hess, EV | 1 |
| Miró, O | 1 |
| Pedrol, E | 1 |
| Cebrián, M | 1 |
| Masanés, F | 1 |
| Casademont, J | 1 |
| Mallolas, J | 1 |
| Grau, JM | 1 |
| Ansevin, CF | 1 |
| Ricker, K | 1 |
| Müller-Jenssen, A | 1 |
| Töpfer, M | 1 |
| Pongratz, DE | 1 |
| Jerusalem, F | 1 |
| Ramos-Niembro, F | 1 |
| Alarcón-Segovia, D | 1 |
| Hernández-Ortíz, J | 1 |
| Miller, RG | 1 |
| Lössner, J | 1 |
| Kühn, HJ | 1 |
| Lehmann, J | 1 |
| Ziegan, J | 1 |
| Csuka, M | 1 |
| McCarty, DJ | 1 |
| Clayton, R | 1 |
| Safdar, SH | 1 |
| Krantz, SB | 1 |
| Brown, EB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901] | Phase 2 | 60 participants | Interventional | 1999-02-28 | Completed | ||
| Effectiveness of a Simple Designed Programme of Home Based Exercise in Preventing Fall and Improving Balance and Strength in Older People With Mild to Moderate Balance Dysfunction: A Randomized Controlled Trials[NCT02089815] | 439 participants (Actual) | Interventional | 2013-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for azathioprine and Muscle Disorders
| Article | Year |
|---|---|
"Mechanic's hands": a misleading cutaneous sign of the antisynthetase syndrome.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Antinuclear; Azathioprine; Cyclophosphamide; Diag | 2007 |
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
[Treatment of myopathies and spinal muscular atrophies (author's transl)].
Topics: Amyotrophic Lateral Sclerosis; Azathioprine; Collagen Diseases; Dermatomyositis; Glycogen Storage Di | 1978 |
Neuropathies and myopathies complicating HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Action Potentials; Adult; Antiviral Agents; Azathioprine; Combin | 1991 |
2 trials available for azathioprine and Muscle Disorders
| Article | Year |
|---|---|
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati | 1983 |
Myopathy in long-term AZT therapy: clinical, electrophysiological and biopsy study in 67 HIV+ subjects.
Topics: Adult; Azathioprine; Biopsy; Creatine Kinase; Electromyography; Female; HIV Seropositivity; Humans; | 1993 |
22 other studies available for azathioprine and Muscle Disorders
| Article | Year |
|---|---|
[Subacute Flaccid Tetraparesis].
Topics: Autoantibodies; Autoimmune Diseases; Azathioprine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhib | 2022 |
Immune-mediated rippling muscle disease in a patient with treated hypothyroidism.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Female; Humans; Hypothyroidism; Immunologic Facto | 2017 |
When Statins Cause an Autoimmune Response: A Report of a Severe Case of Rhabdomyolysis.
Topics: Aged; Atorvastatin; Autoantibodies; Autoimmune Diseases; Azathioprine; Creatine Kinase; Humans; Hydr | 2020 |
Febuxostat as a novel option to optimize thiopurines' metabolism in patients with inadequate metabolite levels.
Topics: Adult; Azathioprine; Drug Interactions; Enzyme Inhibitors; Febuxostat; Female; Guanine Nucleotides; | 2014 |
Rapidly Reversible Winging Scapula.
Topics: Autoantibodies; Autoimmune Diseases; Azathioprine; Deltoid Muscle; Female; Humans; Immunoglobulins, | 2015 |
Patient with statin-associated immune-mediated necrotizing myopathy presenting with subcutaneous edema, persistent bulbar weakness and absent anti-HMGCR.
Topics: Aged; Autoantibodies; Azathioprine; Biopsy; Bulbar Palsy, Progressive; Edema; Glucocorticoids; Human | 2017 |
Immune-mediated rippling muscle disease with myasthenia gravis: a report of seven patients with long-term follow-up in two.
Topics: Adult; Aged; Autoantibodies; Azathioprine; Caveolae; Caveolin 3; Cholinesterase Inhibitors; Electrom | 2009 |
Muscular polyarteritis nodosa.
Topics: Adult; Azathioprine; Biopsy; Drug Therapy, Combination; Electromyography; Follow-Up Studies; Gait; G | 2012 |
[Dropped head plus syndrome; a case report].
Topics: Aged; Azathioprine; Electromyography; Humans; Immunosuppressive Agents; Male; Muscular Diseases; Nec | 2003 |
[Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case].
Topics: Aged; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diagnosis, Differential; Diuretics; Doxazosi | 2004 |
A method for extracting muscle information from serum creatine kinase measurements--its potential value in the monitoring and management of inflammatory muscle disease.
Topics: Animals; Azathioprine; Clinical Enzyme Tests; Creatine Kinase; Drug Interactions; Humans; Indoles; I | 2006 |
Plasma exchange and immunosuppressive drug treatment in the Lambert-Eaton myasthenic syndrome.
Topics: Action Potentials; Adult; Azathioprine; Carcinoma, Small Cell; Combined Modality Therapy; Electric S | 1984 |
Plasmapheresis and immunosuppressive drug therapy in the Eaton-Lambert syndrome.
Topics: Action Potentials; Aged; Azathioprine; Electric Stimulation; Electromyography; Female; Humans; Male; | 1982 |
Rheumatic diseases and AIDS--is the association real?
Topics: Acquired Immunodeficiency Syndrome; Adult; Azathioprine; Female; Humans; Male; Muscular Diseases; Pa | 1993 |
Skeletal muscle studies in patients with HIV-related wasting syndrome.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Female; HIV Wasting Syndrome; Humans; Immunos | 1997 |
Immunosuppressive treatment of rippling muscles in patients with myasthenia gravis.
Topics: Adult; Azathioprine; Humans; Immunosuppressive Agents; Male; Middle Aged; Muscle Contraction; Muscul | 1999 |
Articular manifestations of mixed connective tissue disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Azathioprine; Child; Female; Huma | 1979 |
[Secondary muscular carnitine deficiency following immunosuppressive treatment].
Topics: Adult; Azathioprine; Carnitine; Humans; Lipid Metabolism; Male; Muscles; Muscular Diseases; Myositis | 1989 |
Simple method for measurement of lower extremity muscle strength.
Topics: Adult; Age Factors; Aged; Azathioprine; Creatine Kinase; Female; Humans; Leg; Male; Middle Aged; Mus | 1985 |
Treatment of myasthenia--I.
Topics: Adrenocorticotropic Hormone; Azathioprine; Bronchial Neoplasms; Carcinoma; Cholinesterase Inhibitors | 1971 |
Letter: Azathioprine in psoriasis.
Topics: Azathioprine; Humans; Male; Middle Aged; Muscle Contraction; Muscular Diseases; Psoriasis | 1974 |
Successful immunosuppressive treatment of erythroid aplasia appearing after thymectomy.
Topics: Anemia, Aplastic; Antibodies, Antinuclear; Azathioprine; Bone Marrow; Cyclophosphamide; Erythropoies | 1970 |