azathioprine has been researched along with Multiple Primary Neoplasms in 18 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 7.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 3.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| "Left breast cancer was diagnosed 9 years after the renal transplantation, then colon cancers and meningeal epidermal meningioma were diagnosed, 10 years and 12 years post-transplant, respectively." | 2.42 | Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case. ( Asahara, T; Dohi, K; Fukuda, Y; Hayamizu, K; Ikeda, S; Kataoka, T; Kitayama, T; Marubayashi, S; Ohdan, H; Okajima, M; Okimoto, T; Sugino, K; Tashiro, H, 2004) |
| "In 7 transplant recipients with skin cancer, the mean SCE frequency was 14." | 1.27 | Sister chromatid exchange in lymphocytes from renal transplant recipients with and without cancer. ( Kelly, GE; Sheil, AG, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imko-Walczuk, B | 1 |
| Kryś, A | 1 |
| Lizakowski, S | 1 |
| Dębska-Ślizień, A | 1 |
| Rutkowski, B | 1 |
| Biernat, W | 1 |
| Wojnarowska, F | 1 |
| Guenova, E | 1 |
| Lichte, V | 1 |
| Hoetzenecker, W | 1 |
| Woelbing, F | 1 |
| Moehrle, M | 1 |
| Roecken, M | 1 |
| Schaller, M | 1 |
| Fogo, AJ | 1 |
| Hunt, JB | 1 |
| Clement, M | 1 |
| Kitayama, T | 1 |
| Marubayashi, S | 1 |
| Hayamizu, K | 1 |
| Tashiro, H | 1 |
| Ohdan, H | 1 |
| Ikeda, S | 1 |
| Okimoto, T | 1 |
| Okajima, M | 1 |
| Kataoka, T | 1 |
| Sugino, K | 1 |
| Asahara, T | 1 |
| Fukuda, Y | 1 |
| Dohi, K | 1 |
| Kelly, GE | 1 |
| Sheil, AG | 1 |
| Johnson, F | 1 |
| Hunt, S | 1 |
| Volgger, B | 1 |
| Marth, C | 1 |
| Zeimet, A | 1 |
| Müller-Holzner, E | 1 |
| Ruth, N | 1 |
| Dapunt, O | 1 |
| Aebischer, MC | 1 |
| Zala, LB | 1 |
| Braathen, LR | 1 |
| Veness, MJ | 1 |
| Hall, RL | 1 |
| Leahy, MF | 1 |
| Bowen-Simpkins, P | 1 |
| Hull, MG | 1 |
| Cohen, LM | 1 |
| Tyring, SK | 1 |
| Rády, P | 1 |
| Callen, JP | 1 |
| Choy, DS | 1 |
| Gearhart, RP | 1 |
| Gould, WJ | 1 |
| Sauer, J | 1 |
| Jacobson, L | 1 |
| Rosenthal, B | 1 |
| Xerri, L | 1 |
| Payan, MJ | 1 |
| Choux, R | 1 |
| Gros, N | 1 |
| Hassoun, J | 1 |
| Chamlian, A | 1 |
| Blin, D | 1 |
| Monties, JR | 1 |
| Krickeberg, H | 1 |
| Dahlem, K | 1 |
| Osterwald, L | 1 |
| Jalota, R | 1 |
| Eichwald, EJ | 1 |
| Newman, DM | 1 |
| Walter, JB | 1 |
2 reviews available for azathioprine and Multiple Primary Neoplasms
| Article | Year |
|---|---|
Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case.
Topics: Azathioprine; Breast Neoplasms; Carcinoma, Ductal, Breast; Colonic Neoplasms; Colonic Polyps; Drug T | 2004 |
Development of multiple carcinomas in a long term survivor of Wegener's granulomatosis treated with immunosuppressive drugs.
Topics: Adult; Azathioprine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Gran | 1989 |
16 other studies available for azathioprine and Multiple Primary Neoplasms
| Article | Year |
|---|---|
Sebaceous carcinoma in patients receiving long-term immunosuppresive treatment: case report and literature review.
Topics: Aged, 80 and over; Azathioprine; Carcinoma, Squamous Cell; Cyclosporine; Fatal Outcome; Female; Huma | 2014 |
Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Topics: Aged; Antineoplastic Agents, Alkylating; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Ce | 2009 |
Multiple cutaneous malignancies arising in a patient with Crohn disease treated with concomitant azathioprine and antitumour necrosis factor-alpha.
Topics: Adult; Azathioprine; Crohn Disease; Drug Therapy, Combination; Female; Humans; Immunosuppressive Age | 2010 |
Sister chromatid exchange in lymphocytes from renal transplant recipients with and without cancer.
Topics: Azathioprine; Crossing Over, Genetic; Humans; Immunosuppression Therapy; Kidney Transplantation; Lym | 1983 |
Recurrent lymphoma in a cardiac allograft recipient.
Topics: Azathioprine; Cyclosporine; Follow-Up Studies; Graft Rejection; Heart Transplantation; Humans; Lung | 1994 |
Fulminant course of a microinvasive vulvar carcinoma in an immunosuppressed woman.
Topics: Adult; Azathioprine; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Condylomata Acuminata | 1997 |
Kaposi's sarcoma as manifestation of immunosuppression in organ transplant recipients.
Topics: Anti-Inflammatory Agents; Azathioprine; Combined Modality Therapy; Cyclosporine; Graft Rejection; He | 1997 |
Cardiac transplant-related cutaneous malignancies in an Australian recipient: immunosuppression, friend or foe?
Topics: Adult; Australia; Azathioprine; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cy | 1998 |
Acquired Factor VIII autoantibody: four cases demonstrating the heterogenous nature of this condition and problems involved in diagnosis and treatment.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Azathiop | 2001 |
Intraepithelial vaginal neoplasia following immunosuppressive therapy treated with topical 5-Fu.
Topics: Administration, Topical; Adult; Azathioprine; Biopsy; Carcinoma, Squamous Cell; Cervix Uteri; Female | 1975 |
Human papillomavirus type 11 in multiple squamous cell carcinomas in a patient with subacute cutaneous lupus erythematosus.
Topics: Acute Disease; Azathioprine; Carcinoma, Squamous Cell; Cocarcinogenesis; Humans; Lupus Erythematosus | 1992 |
An exceptional 18-year follow-up after cardiac transplantation. How can malignancies occur during immunosuppressive therapy?
Topics: Adenocarcinoma, Papillary; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up | 1989 |
[Development of multiple precancerous conditions and malignant skin tumors in immunosuppressive therapy].
Topics: Azathioprine; Fluocortolone; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Trans | 1988 |
[Examples for possible tumor induction by immunosuppressive and cytostatic drugs (case studies)].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined | 1986 |
Chronic immunosuppression and occult lymphoma: a case report.
Topics: Adult; Azathioprine; Bone Neoplasms; Cadaver; Carcinoma, Squamous Cell; Cytomegalovirus Infections; | 1972 |
Multiple dermatofibromas in patients with systemic lupus erythematosus on immunosuppressive therapy.
Topics: Adult; Azathioprine; Female; Fibroma; Humans; Lupus Erythematosus, Systemic; Neoplasms, Multiple Pri | 1973 |