azathioprine has been researched along with Mouth Diseases in 23 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Mouth Diseases: Diseases involving the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " low dose oral prednisone on alternate days plus azathioprine every day (Lever's mini treatment: LMT) in oral pemphigus." | 7.77 | High dose oral prednisone vs. prednisone plus azathioprine for the treatment of oral pemphigus: a retrospective, bi-centre, comparative study. ( Apalla, Z; Chaidemenos, G; Ioannides, D; Koussidou, T; Papagarifallou, I, 2011) |
| "This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)." | 7.70 | Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000) |
| "Sixteen patients affected by oral pemphigus vulgaris were retrospectively examined to illustrate the natural course of the disease and to describe the efficacy of the treatment we utilised." | 6.41 | Oral pemphigus: long term behaviour and clinical response to treatment with deflazacort in sixteen cases. ( Bucci, E; Carbone, R; Lo Muzio, L; Mignogna, MD; Mignogna, RE; Ruoppo, E, 2000) |
| " low dose oral prednisone on alternate days plus azathioprine every day (Lever's mini treatment: LMT) in oral pemphigus." | 3.77 | High dose oral prednisone vs. prednisone plus azathioprine for the treatment of oral pemphigus: a retrospective, bi-centre, comparative study. ( Apalla, Z; Chaidemenos, G; Ioannides, D; Koussidou, T; Papagarifallou, I, 2011) |
| "This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)." | 3.70 | Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000) |
| "The etiology of pemphigus vulgaris is still unknown, although the disease has attracted considerable interest." | 2.44 | Oral pemphigus vulgaris: a case report with review of the literature. ( Cakur, B; Dagistan, S; Goregen, M; Miloglu, O, 2008) |
| "Pemphigus is a group of potentially life-threatening autoimmune diseases characterized by cutaneous and/or mucosal blistering." | 2.43 | Number II. Pemphigus vulgaris. ( Black, M; Mignogna, MD; Scully, C, 2005) |
| "Sixteen patients affected by oral pemphigus vulgaris were retrospectively examined to illustrate the natural course of the disease and to describe the efficacy of the treatment we utilised." | 2.41 | Oral pemphigus: long term behaviour and clinical response to treatment with deflazacort in sixteen cases. ( Bucci, E; Carbone, R; Lo Muzio, L; Mignogna, MD; Mignogna, RE; Ruoppo, E, 2000) |
| "Treatment with prednisolone and azathioprine caused rapid and complete healing." | 1.33 | [Desmoglein 1-negative, desmoglein 3-positive pemphigus herpetiformis with involvement of oral mucous membranes]. ( Brod, C; Fierlbeck, G; Metzler, G; Röcken, M; Schaller, M; Sönnichsen, K, 2005) |
| "Oral lichen planus was found mainly in women and most commonly on the buccal mucosa." | 1.28 | A prospective study of findings and management in 214 patients with oral lichen planus. ( Giannotti, K; Gorsky, M; Lozada-Nur, F; Silverman, S, 1991) |
| "Two cases of pemphigus vulgaris in which oral lesions were the first signs of the disease are reported." | 1.28 | Pemphigus vulgaris of the oral mucosa: report of two cases. ( Brouwer, TJ; Raghoebar, GM; Schoots, CJ, 1991) |
| "There were no deaths due to infection during the 10-month study period." | 1.26 | Oral infection in immunosuppressed renal transplant patients. ( Cohen, G; Greenberg, MS, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (26.09) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, S | 1 |
| De, D | 1 |
| Handa, S | 1 |
| Ratho, RK | 1 |
| Bhandari, S | 1 |
| Pal, A | 1 |
| Kamboj, P | 1 |
| Sarkar, S | 1 |
| Hullah, EA | 1 |
| Blaker, PA | 1 |
| Marinaki, AM | 1 |
| Escudier, MP | 1 |
| Sanderson, JD | 1 |
| Gissi, DB | 1 |
| Tarsitano, A | 1 |
| Baldovini, C | 1 |
| Gabusi, A | 1 |
| Dagistan, S | 1 |
| Goregen, M | 1 |
| Miloglu, O | 1 |
| Cakur, B | 1 |
| Chaidemenos, G | 1 |
| Apalla, Z | 1 |
| Koussidou, T | 1 |
| Papagarifallou, I | 1 |
| Ioannides, D | 1 |
| Fernández, S | 1 |
| España, A | 1 |
| Navedo, M | 1 |
| Barona, L | 1 |
| Black, M | 1 |
| Mignogna, MD | 2 |
| Scully, C | 1 |
| Brod, C | 1 |
| Fierlbeck, G | 1 |
| Metzler, G | 1 |
| Sönnichsen, K | 1 |
| Röcken, M | 1 |
| Schaller, M | 1 |
| Lozada, F | 1 |
| Farthing, PM | 1 |
| Maragou, P | 1 |
| Coates, M | 1 |
| Tatnall, F | 1 |
| Leigh, IM | 1 |
| Williams, DM | 1 |
| Epstein, JB | 1 |
| Nantel, S | 1 |
| Sheoltch, SM | 1 |
| Lo Muzio, L | 1 |
| Mignogna, RE | 1 |
| Carbone, R | 1 |
| Ruoppo, E | 1 |
| Bucci, E | 1 |
| Sirois, D | 1 |
| Leigh, JE | 1 |
| Sollecito, TP | 1 |
| Greenberg, MS | 1 |
| Cohen, G | 1 |
| Westbrook, SD | 1 |
| Lamey, PJ | 2 |
| Rees, TD | 2 |
| Binnie, WH | 2 |
| Rankin, KV | 2 |
| Wright, JM | 1 |
| Simpson, NB | 1 |
| Silverman, S | 1 |
| Gorsky, M | 1 |
| Lozada-Nur, F | 1 |
| Giannotti, K | 1 |
| Firth, N | 1 |
| Rich, A | 1 |
| Varigos, G | 1 |
| Reade, PC | 1 |
| Raghoebar, GM | 1 |
| Brouwer, TJ | 1 |
| Schoots, CJ | 1 |
| Tan, KN | 1 |
| Medak, H | 1 |
| Cohen, L | 1 |
| Burlakow, P | 1 |
| Macmillan, AL | 1 |
| Roberts, SO | 1 |
| Dave, VK | 1 |
| Vickers, CF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-Label Pilot Study to Evaluate the Safety and Efficacy of Apremilast (CC-10004) in the Treatment of Moderate to Severe Lichen Planus[NCT01041625] | Phase 2 | 10 participants (Anticipated) | Interventional | 2010-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for azathioprine and Mouth Diseases
| Article | Year |
|---|---|
A practical guide to the use of thiopurines in oral medicine.
Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Immunosuppressive Agents; | 2015 |
Oral pemphigus vulgaris: a case report with review of the literature.
Topics: Adult; Azathioprine; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Mouth Diseases; Pemp | 2008 |
Number II. Pemphigus vulgaris.
Topics: Adrenal Cortex Hormones; Azathioprine; Blister; Cadherins; Cytoskeletal Proteins; Desmoglein 1; Desm | 2005 |
Oral pemphigus: long term behaviour and clinical response to treatment with deflazacort in sixteen cases.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Cyclophosphamide; Drug Co | 2000 |
19 other studies available for azathioprine and Mouth Diseases
| Article | Year |
|---|---|
Identification of factors associated with treatment refractoriness of oral lesions in pemphigus vulgaris.
Topics: Adult; Antibodies; Azathioprine; Cyclophosphamide; Dermatologic Agents; Desmoglein 1; Desmoglein 3; | 2017 |
Unusual Histological Evidence of Dysplasia in a Case of Oral Pemphigus Vulgaris: A Potential Diagnostic Challenge.
Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Drug Therapy, Combination; Humans; Immunosuppressive A | 2016 |
High dose oral prednisone vs. prednisone plus azathioprine for the treatment of oral pemphigus: a retrospective, bi-centre, comparative study.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Dose-Response Relationshi | 2011 |
Study of oral, ear, nose and throat involvement in pemphigus vulgaris by endoscopic examination.
Topics: Azathioprine; Drug Therapy, Combination; Ear Diseases; Endoscopy; Glucocorticoids; Humans; Immunosup | 2012 |
[Desmoglein 1-negative, desmoglein 3-positive pemphigus herpetiformis with involvement of oral mucous membranes].
Topics: Azathioprine; Desmoglein 1; Desmoglein 3; Female; Humans; Middle Aged; Mouth Diseases; Mouth Mucosa; | 2005 |
Prednisone and azathioprine in the treatment of patient with vesiculoerosive oral diseases.
Topics: Adult; Aged; Azathioprine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle A | 1981 |
Characteristics of the oral lesions in patients with cutaneous recurrent erythema multiforme.
Topics: Adolescent; Adult; Aged; Azathioprine; Erythema Multiforme; Female; Humans; Male; Middle Aged; Mouth | 1995 |
Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease.
Topics: Administration, Topical; Adult; Anemia, Aplastic; Azathioprine; Bone Marrow Transplantation; Candidi | 2000 |
Oral pemphigus vulgaris preceding cutaneous lesions: recognition and diagnosis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Corneal Ulcer; Cyclophosphamide | 2000 |
Oral infection in immunosuppressed renal transplant patients.
Topics: Adult; Azathioprine; Bacteria; Fungi; Humans; Immunosuppression Therapy; Infections; Kidney Transpla | 1977 |
Dental management of patients receiving hemodialysis and kidney transplants.
Topics: Anti-Bacterial Agents; Azathioprine; Dental Calculus; Dental Care; Humans; Jaw Diseases; Kidney Dise | 1978 |
Mucous membrane pemphigoid. Treatment experience at two institutions.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Cyclophosp | 1992 |
Oral presentation of pemphigus vulgaris and its response to systemic steroid therapy.
Topics: Adult; Aged; Azathioprine; Cyclophosphamide; Female; Humans; Male; Middle Aged; Mouth Diseases; Pemp | 1992 |
A prospective study of findings and management in 214 patients with oral lichen planus.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Azathioprine; Carboxymethylcellulose Sodium; F | 1991 |
Oral pemphigus vulgaris in young adults.
Topics: Adult; Autoimmune Diseases; Azathioprine; Candidiasis, Oral; Female; Humans; Male; Mouth Diseases; P | 1991 |
Pemphigus vulgaris of the oral mucosa: report of two cases.
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Azathioprine; Female; Humans; Mouth Diseases; Mouth Muc | 1991 |
Focal epithelial hyperplasia in a Mexican Indian.
Topics: Azathioprine; Child; Cyclophosphamide; Epithelium; Estrogens, Conjugated (USP); Glomerulonephritis; | 1969 |
Porokeratosis of Mibelli after renal transplantation.
Topics: Adult; Antigens; Azathioprine; Female; Humans; Keratosis; Kidney Transplantation; Mouth Diseases; Po | 1974 |
Azathioprine in the treatment of muco-cutaneous pemphigoid.
Topics: Azathioprine; Blister; Conjunctivitis; Female; Humans; Iritis; Male; Middle Aged; Mouth Diseases; Pr | 1974 |