azathioprine has been researched along with Motor Neuron Disease in 3 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barber, CE | 1 |
| Lee, P | 1 |
| Steinhart, AH | 1 |
| Lazarou, J | 1 |
| Ryan, A | 1 |
| Nor, AM | 1 |
| Costigan, D | 1 |
| Foley-Nolan, D | 1 |
| El-Rafie, A | 1 |
| Farrell, MA | 1 |
| Hardiman, O | 1 |
| Baba, M | 1 |
| Matsunaga, M | 1 |
1 review available for azathioprine and Motor Neuron Disease
| Article | Year |
|---|---|
[Chronic inflammatory demyelinating polyneuropathy: multifocal demyelinating neuropathy].
Topics: Adolescent; Adult; Aged; Azathioprine; Child; Chronic Disease; Demyelinating Diseases; Female; Human | 1992 |
2 other studies available for azathioprine and Motor Neuron Disease
| Article | Year |
|---|---|
Multifocal motor neuropathy with conduction block following treatment with infliximab.
Topics: Adult; Antibodies, Monoclonal; Antirheumatic Agents; Azathioprine; Crohn Disease; Electromyography; | 2010 |
Polymyositis masquerading as motor neuron disease.
Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Biopsy; Cervical Vertebrae; Deglutition Disorders; Diag | 2003 |